产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
Mmp1催化域
目录 :
3B8D12
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
3B8D12
反应物种 :
黑腹果蝇
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀
文章摘录数: 30
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 黑腹果蝇; 1:10; 图 7s2
Parvy J, Yu Y, Dostálová A, Kondo S, Kurjan A, Bulet P, et al. The antimicrobial peptide defensin cooperates with tumour necrosis factor to drive tumour cell death in Drosophila. elife. 2019;8: pubmed 出版商
  • 免疫组化; 黑腹果蝇; 1:30; 图 f7s2e
Cosolo A, Jaiswal J, Csordás G, Grass I, Uhlirova M, Classen A. JNK-dependent cell cycle stalling in G2 promotes survival and senescence-like phenotypes in tissue stress. elife. 2019;8: pubmed 出版商
  • 免疫组化; 黑腹果蝇; 1:10; 图 S1A
Raza Q, Vanderploeg J, Jacobs J. Matrix Metalloproteinases are required for membrane motility and lumenogenesis during Drosophila heart development. PLoS ONE. 2017;12:e0171905 pubmed 出版商
  • 免疫组化; 黑腹果蝇; 1:100; 图 3a
Bangi E, Murgia C, Teague A, Sansom O, Cagan R. Functional exploration of colorectal cancer genomes using Drosophila. Nat Commun. 2016;7:13615 pubmed 出版商
  • 免疫组化; 黑腹果蝇; 图 3
Levine B, Cagan R. Drosophila Lung Cancer Models Identify Trametinib plus Statin as Candidate Therapeutic. Cell Rep. 2016;14:1477-1487 pubmed 出版商
Pinal N, Martin M, Medina I, Morata G. Short-term activation of the Jun N-terminal kinase pathway in apoptosis-deficient cells of Drosophila induces tumorigenesis. Nat Commun. 2018;9:1541 pubmed 出版商
Aggarwal P, Gera J, Ghosh S, Mandal L, Mandal S. Noncanonical Decapentaplegic Signaling Activates Matrix Metalloproteinase 1 To Restrict Hedgehog Activity and Limit Ectopic Eye Differentiation in Drosophila. Genetics. 2017;207:197-213 pubmed 出版商
Taylor E, Alqadri N, Dodgson L, Mason D, Lyulcheva E, Messina G, et al. MRL proteins cooperate with activated Ras in glia to drive distinct oncogenic outcomes. Oncogene. 2017;36:4311-4322 pubmed 出版商
Toggweiler J, Willecke M, Basler K. The transcription factor Ets21C drives tumor growth by cooperating with AP-1. Sci Rep. 2016;6:34725 pubmed 出版商
Takino K, Ohsawa S, Igaki T. Loss of Rab5 drives non-autonomous cell proliferation through TNF and Ras signaling in Drosophila. Dev Biol. 2014;395:19-28 pubmed 出版商
de Vreede G, Schoenfeld J, Windler S, Morrison H, Lu H, Bilder D. The Scribble module regulates retromer-dependent endocytic trafficking during epithelial polarization. Development. 2014;141:2796-802 pubmed 出版商
Herranz H, Weng R, Cohen S. Crosstalk between epithelial and mesenchymal tissues in tumorigenesis and imaginal disc development. Curr Biol. 2014;24:1476-84 pubmed 出版商
Manhire Heath R, Golenkina S, Saint R, Murray M. Netrin-dependent downregulation of Frazzled/DCC is required for the dissociation of the peripodial epithelium in Drosophila. Nat Commun. 2013;4:2790 pubmed 出版商
Nakajima Y, Meyer E, Kroesen A, McKinney S, Gibson M. Epithelial junctions maintain tissue architecture by directing planar spindle orientation. Nature. 2013;500:359-62 pubmed 出版商
Fernandez B, Jezowska B, Janody F. Drosophila actin-Capping Protein limits JNK activation by the Src proto-oncogene. Oncogene. 2014;33:2027-39 pubmed 出版商
Khoo P, Allan K, Willoughby L, Brumby A, Richardson H. In Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1-Rok-Myosin-II and JNK signalling. Dis Model Mech. 2013;6:661-78 pubmed 出版商
Chountala M, Vakaloglou K, Zervas C. Parvin overexpression uncovers tissue-specific genetic pathways and disrupts F-actin to induce apoptosis in the developing epithelia in Drosophila. PLoS ONE. 2012;7:e47355 pubmed 出版商
Lee S, Park J, Kim Y, Chung H, Yoo M. Requirement of matrix metalloproteinase-1 for intestinal homeostasis in the adult Drosophila midgut. Exp Cell Res. 2012;318:670-81 pubmed 出版商
Stevens L, Page McCaw A. A secreted MMP is required for reepithelialization during wound healing. Mol Biol Cell. 2012;23:1068-79 pubmed 出版商
Robinson B, Moberg K. Drosophila endocytic neoplastic tumor suppressor genes regulate Sav/Wts/Hpo signaling and the c-Jun N-terminal kinase pathway. Cell Cycle. 2011;10:4110-8 pubmed 出版商
Jezowska B, Fernández B, Amândio A, Duarte P, Mendes C, Bras Pereira C, et al. A dual function of Drosophila capping protein on DE-cadherin maintains epithelial integrity and prevents JNK-mediated apoptosis. Dev Biol. 2011;360:143-59 pubmed 出版商
VanZomeren Dohm A, Sarro J, Flannery E, Duman Scheel M. The Drosophila Netrin receptor frazzled/DCC functions as an invasive tumor suppressor. BMC Dev Biol. 2011;11:41 pubmed 出版商
Huang H, Du G, Chen H, Liang X, Li C, Zhu N, et al. Drosophila Smt3 negatively regulates JNK signaling through sequestering Hipk in the nucleus. Development. 2011;138:2477-85 pubmed 出版商
Glasheen B, Robbins R, Piette C, Beitel G, Page McCaw A. A matrix metalloproteinase mediates airway remodeling in Drosophila. Dev Biol. 2010;344:772-83 pubmed 出版商
Neisch A, Speck O, Stronach B, Fehon R. Rho1 regulates apoptosis via activation of the JNK signaling pathway at the plasma membrane. J Cell Biol. 2010;189:311-23 pubmed 出版商
Glasheen B, Kabra A, Page McCaw A. Distinct functions for the catalytic and hemopexin domains of a Drosophila matrix metalloproteinase. Proc Natl Acad Sci U S A. 2009;106:2659-64 pubmed 出版商
Rodahl L, Haglund K, Sem Jacobsen C, Wendler F, Vincent J, Lindmo K, et al. Disruption of Vps4 and JNK function in Drosophila causes tumour growth. PLoS ONE. 2009;4:e4354 pubmed 出版商
Miller C, Page McCaw A, Broihier H. Matrix metalloproteinases promote motor axon fasciculation in the Drosophila embryo. Development. 2008;135:95-109 pubmed
Zhang S, Dailey G, Kwan E, Glasheen B, Sroga G, Page McCaw A. An MMP liberates the Ninjurin A ectodomain to signal a loss of cell adhesion. Genes Dev. 2006;20:1899-910 pubmed 出版商
Page McCaw A, Serano J, Sante J, Rubin G. Drosophila matrix metalloproteinases are required for tissue remodeling, but not embryonic development. Dev Cell. 2003;4:95-106 pubmed
产品信息
内部号码 :
1570
名称 :
3B8D12
Depositor Name :
Rubin, G.M.
Depositor Institution :
HHMI / Janelia Farm Research
Date Deposited :
8/2/06
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
抗原 :
Mmp1催化域
抗原物种 :
果蝇
宿主物种 :
小鼠
抗体亚型 :
MIgG1, kappa light chain
Isotype for catalog (legacy) :
IgG1, kappa light chain
Positive Tested Species Reactivity :
果蝇
Species Tested (legacy) :
果蝇
Initial Publication Pubmed ID :
12530966
Depositor Notes (Special Instructions) :
This mAb is often used as a 1:1:1 cocktail when combined with 3A6B4 and 5H7B1.
Collections :
果蝇抗原, 酶, 细胞外基质蛋白
搜索关键词 :
Rubin, Gerald M., Mmp1 catalytic domain, Drosophila, MIgG1, kappa light chain, Drosophila, MMP1, dm1-MMP; Dm1-MMP; Dmel CG4859; dmmp1; dMMP1; , AB_579781, monoclonal
抗原分子量 :
Predicted: 64.7kDa; Apparent: multiple bands at 46, 52, 64 and 74kDa
基因 :
MMP1
Alternate Gene Name(s) :
dm1-MMP; Dm1-MMP; Dmel CG4859; dmmp1; dMMP1;
UniProt数据库编号 :
Q9W122
抗体登记处号码 :
AB_579781
免疫原 :
GST fused to recombinant Mmp1 catalytic domain (amino acids 137-299 of Mmp1)
免疫原序列 :
Recombinant Mmp1 catalytic domain (amino acids 137-299 of Mmp1)
克隆性 :
单克隆
Myeloma Strain :
P3XAg8.653
表位定位 :
Yes
表位定位Pubmed登录号 :
12530966
Recommended Applications :
免疫荧光, 免疫组化, 免疫沉淀, 免疫印迹
Immunoblotting (legacy) :
yes
免疫组化PubMed IDs :
18045838
免疫荧光PubMed IDs :
16815999 12530966 23644660 20513443 23077599 24225841 22101275 23324326 21963538 19194501 21561986 23873041 22262460 25224221 22265916 21672235 20404112 24980505 29670104
免疫印迹PubMed IDs :
16815999 19196956 22262460
免疫沉淀PubMed IDs :
16815999
PubMed IDs :
25005475
其他信息 :
This antibody has been used for immunostaining as a monoclonal antibody cocktail with 3A6B4 and 5H7B11.
DSHB增长培养基 :
Iscove's
References (legacy) :
Genes Dev. 20(14), 1899-1910.; Dev. Cell 4, 95-106.
公司信息
Developmental Studies Hybridoma Bank
University of Iowa
dshb@uiowa.edu
http://dshb.biology.uiowa.edu
公司总部: 美国
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构,为生命科学研究领域及诊断领域,提供高质量的抗体等产品。