产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
Engrailed/invected gene products
目录 :
4D9 anti-engrailed/invected
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
4D9 anti-engrailed/invected
反应物种 :
果蝇
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀
文章摘录数: 51
出版应用/物种/样本/稀释 | 参考文献 |
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Baratte S, Andouche A, Bonnaud L. Engrailed in cephalopods: a key gene related to the emergence of morphological novelties. Dev Genes Evol. 2007;217:353-62 pubmed
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Waldrop S, Chan C, Cagatay T, Zhang S, Rousset R, Mack J, et al. An unconventional nuclear localization motif is crucial for function of the Drosophila Wnt/wingless antagonist Naked cuticle. Genetics. 2006;174:331-48 pubmed
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Kent D, Bush E, Hooper J. Roadkill attenuates Hedgehog responses through degradation of Cubitus interruptus. Development. 2006;133:2001-10 pubmed
| |
Stehr C, Linbo T, Incardona J, Scholz N. The developmental neurotoxicity of fipronil: notochord degeneration and locomotor defects in zebrafish embryos and larvae. Toxicol Sci. 2006;92:270-8 pubmed
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Harzsch S. Evolution of identified arthropod neurons: the serotonergic system in relation to engrailed-expressing cells in the embryonic ventral nerve cord of the american lobster homarus americanus milne edwards, 1873 (malacostraca, pleocyemata, homarida). Dev Biol. 2003;258:44-56 pubmed
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Nakamura Y, Haines N, Chen J, Okajima T, Furukawa K, Urano T, et al. Identification of a Drosophila gene encoding xylosylprotein beta4-galactosyltransferase that is essential for the synthesis of glycosaminoglycans and for morphogenesis. J Biol Chem. 2002;277:46280-8 pubmed
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Belenkaya T, Han C, Standley H, Lin X, Houston D, Heasman J, et al. pygopus Encodes a nuclear protein essential for wingless/Wnt signaling. Development. 2002;129:4089-101 pubmed
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Nagaso H, Murata T, Day N, Yokoyama K. Simultaneous detection of RNA and protein by in situ hybridization and immunological staining. J Histochem Cytochem. 2001;49:1177-82 pubmed
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Stauber M, Taubert H, Schmidt Ott U. Function of bicoid and hunchback homologs in the basal cyclorrhaphan fly Megaselia (Phoridae). Proc Natl Acad Sci U S A. 2000;97:10844-9 pubmed
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Yu X, Waltzer L, Bienz M. A new Drosophila APC homologue associated with adhesive zones of epithelial cells. Nat Cell Biol. 1999;1:144-51 pubmed
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Muller H, Samanta R, Wieschaus E. Wingless signaling in the Drosophila embryo: zygotic requirements and the role of the frizzled genes. Development. 1999;126:577-86 pubmed
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White P, Aberle H, Vincent J. Signaling and adhesion activities of mammalian beta-catenin and plakoglobin in Drosophila. J Cell Biol. 1998;140:183-95 pubmed
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Serrano N, Brock H, Demeret C, Dura J, Randsholt N, Kornberg T, et al. polyhomeotic appears to be a target of engrailed regulation in Drosophila. Development. 1995;121:1691-703 pubmed
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Baird A, Cuthbert A, MacVinish L. Type 1 hypersensitivity reactions in reconstructed tissues using syngeneic cell types. Br J Pharmacol. 1987;91:857-69 pubmed
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Patel N, Martin Blanco E, Coleman K, Poole S, Ellis M, Kornberg T, et al. Expression of engrailed proteins in arthropods, annelids, and chordates. Cell. 1989;58:955-68 pubmed
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产品信息
内部号码 :
3562
名称 :
4D9 anti-engrailed/invected
Depositor Name :
Goodman, C.
Depositor Institution :
University of California, Berkeley
Date Deposited :
2/1/94
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
抗原 :
Engrailed/invected gene products
抗原物种 :
果蝇
宿主物种 :
小鼠
抗体亚型 :
MIgG1
Isotype for catalog (legacy) :
IgG1, kappa light chain
Positive Tested Species Reactivity :
Beetle,Chicken,Crayfish,Drosophila,Fish,Grasshopper,Lobster,Molluscs,Worm,Xenopus,Zebrafish
Species Tested (legacy) :
Drosophila, grasshopper, crayfish, lobster, zebrafish, chicken, Xenopus; not mouse and moth
Initial Publication Pubmed ID :
2570637
Depositor Notes (Special Instructions) :
This antibody recognizes both the engrailed and invected gene products of Drosophila. The antibody is useful for examining the patterning of segmentation from the cellular blastoderm stage onward. Staining is also seen in a large number of CNS neurons including most of the median neuroblast progeny as well as a small number of PNS neurons. The antibody doesn't recognize engrailed in mouse, human, sea urchin and Manduca sexta (moth).
Collections :
果蝇抗原, 转录因子, 蛙
搜索关键词 :
Goodman, Corey, Engrailed/invected gene products, Drosophila, MIgG1, Drosophila/Grasshopper/CrayFish/Lobster/Zebrafish/Chicken/Xenopus/Worm/Molluscs , En1, En-1, Mo-en.1, AB_528224, monoclonal
抗原分子量 :
Predicted: 59 kDa for en; 61 kDa for in
基因 :
en & in
UniProt数据库编号 :
P02836 P05527
抗体登记处号码 :
AB_528224
Synonyms (Alternate Clone Names) :
4D9
免疫原 :
Invected (C-terminal two-thirds of the invected protein); recombinant.
克隆性 :
单克隆
Myeloma Strain :
NS-1
表位定位 :
Yes
Epitope Location or Sequence :
aa 38-48 of the engrailed homeobox (C-terminal aa 490-500 of engrailed: ELGLNEAQIKI; aa 507-517 of invected)
表位定位Pubmed登录号 :
2570637
Recommended Applications :
Chromatin Immunoprecipitation,Function Blocking,Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot
免疫组化PubMed IDs :
2570637 2570637 9425166 10559900 10995461 11511686 12215432 12781681 17394016 20398650 21477650 27296678 30995487
免疫荧光PubMed IDs :
9876186 10995461 11511686 12781681 20398650 22537495 23154412 19270173 19914184 7600986 27296678 26937007 27640326 27174470 24917506 23459760 29530880 27095493
免疫印迹PubMed IDs :
2570637
免疫沉淀PubMed IDs :
19270173
Function Blocking Pubmed IDs :
2570637 19914184
Gel Supershift Pubmed IDs :
.
DSHB增长培养基 :
Iscove's
References (legacy) :
Cell 58, 955-968.; Nature 367, 429-434.; J. Cell Biol. 140(1), 183-195.; Nature Cell Biol. 1(3), 144-151.; Development 126, 577-586.; Proc. Natl. Acad. Sci. 97(20), 10844-10849.; J. Histochem. Cytochem. 49(9), 1177-1182.; J. Biol. Chem. 277(48), 46280-46288.; Dev. Biol. 258, 44-56.; Dev. Genes Evol. 217, 353-362.; Matrix Biol. 30, 258-266.; Dev. Biol. 366, 382-392.; Development 140(1), 82-92.
公司信息
Developmental Studies Hybridoma Bank
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构,为生命科学研究领域及诊断领域,提供高质量的抗体等产品。
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