产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
NCAM (sialylated form); PSA-NCAM
目录 :
5A5
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
5A5
反应物种 :
人类, 小鼠, brown rat, bantam
应用 :
免疫印迹, 免疫组化, 免疫细胞化学
文章摘录数: 12
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 1:700; 图 2f
Carceller H, Guirado R, Nacher J. Dark exposure affects plasticity-related molecules and interneurons throughout the visual system during adulthood. J Comp Neurol. 2019;: pubmed 出版商
Dieriks B, Dean J, Aronica E, Waldvogel H, Faull R, Curtis M. Differential Fatty Acid-Binding Protein Expression in Persistent Radial Glia in the Human and Sheep Subventricular Zone. Dev Neurosci. 2018;40:145-161 pubmed 出版商
Murray H, Swanson M, Dieriks B, Turner C, Faull R, Curtis M. Neurochemical Characterization of PSA-NCAM+ Cells in the Human Brain and Phenotypic Quantification in Alzheimer's Disease Entorhinal Cortex. Neuroscience. 2018;372:289-303 pubmed 出版商
Xue Y, Qian H, Hu J, Zhou B, Zhou Y, Hu X, et al. Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells. Nat Neurosci. 2016;19:807-15 pubmed 出版商
Niu W, Zang T, Smith D, Vue T, Zou Y, Bachoo R, et al. SOX2 reprograms resident astrocytes into neural progenitors in the adult brain. Stem Cell Reports. 2015;4:780-94 pubmed 出版商
Mich J, Signer R, Nakada D, Pineda A, Burgess R, Vue T, et al. Prospective identification of functionally distinct stem cells and neurosphere-initiating cells in adult mouse forebrain. elife. 2014;3:e02669 pubmed 出版商
Darbinyan A, Kaminski R, White M, Darbinian N, Khalili K. Isolation and propagation of primary human and rodent embryonic neural progenitor cells and cortical neurons. Methods Mol Biol. 2013;1078:45-54 pubmed 出版商
Huang Z, Yu Y, Shimoda Y, Watanabe K, Liu Y. Loss of neural recognition molecule NB-3 delays the normal projection and terminal branching of developing corticospinal tract axons in the mouse. J Comp Neurol. 2012;520:1227-45 pubmed 出版商
Messina D, Alder L, Tresco P. Comparison of pure and mixed populations of human fetal-derived neural progenitors transplanted into intact adult rat brain. Exp Neurol. 2003;184:816-29 pubmed
Joosten E. Developmental expression of N-CAM epitopes in the rat spinal cord during corticospinal tract axon outgrowth and target innervation. Brain Res Dev Brain Res. 1994;78:226-36 pubmed
Dodd J, Morton S, Karagogeos D, Yamamoto M, Jessell T. Spatial regulation of axonal glycoprotein expression on subsets of embryonic spinal neurons. Neuron. 1988;1:105-16 pubmed
Acheson A, Sunshine J, Rutishauser U. NCAM polysialic acid can regulate both cell-cell and cell-substrate interactions. J Cell Biol. 1991;114:143-53 pubmed
产品信息
内部号码 :
2617
名称 :
5A5
Depositor Name :
Jessell, T.M. / Dodd, J. / Brenner-Morton, S.
Depositor Institution :
HHMI/Columbia University
Date Deposited :
3/15/89
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
抗原 :
NCAM (sialylated form); PSA-NCAM
抗原物种 :
大鼠
宿主物种 :
小鼠
抗体亚型 :
MIgM
Isotype for catalog (legacy) :
IgM
Positive Tested Species Reactivity :
鸡, 人类, 小鼠, 大鼠
Species Tested (legacy) :
大鼠, 小鼠, 鸡, 人类
Initial Publication Pubmed ID :
3272160
Depositor Notes (Special Instructions) :
The 5A5 antibody has successfully been used as a panning substrate for human neural stem cells attachment (PMID: 27680492).
Collections :
Cell adhesion,Cell signaling,Cytoskeleton,Human,Neurodevelopment,Stem cell
搜索关键词 :
Jessell, Thomas M / Dodd, Jane, Brenner-Morton, Susan, NCAM (sialylated form); PSA-NCAM, Rat, MIgM, Rat/Mouse/Chicken/Human, Ncam1, Cd56/N-CAM/N-CAM-1/NCAM-1/NCAM-C/NCAMC/Ncam, AB_2314873, monoclonal
抗原分子量 :
Apparent: 300kD
基因 :
神经细胞粘附分子1
Alternate Gene Name(s) :
Cd56/N-CAM/N-CAM-1/NCAM-1/NCAM-C/NCAMC/Ncam
UniProt数据库编号 :
P13596
抗体登记处号码 :
AB_2314873
Synonyms (Alternate Clone Names) :
CD56
免疫原 :
Embryonic spinal cord membranes (rat)
克隆性 :
单克隆
Myeloma Strain :
NS-1
表位定位 :
Yes
Epitope Location or Sequence :
polysialic acid
表位定位Pubmed登录号 :
2050739
Recommended Applications :
免疫荧光, 免疫组化, 免疫印迹
Immunoblotting (legacy) :
Yes
免疫组化PubMed IDs :
21935948 29429526
免疫荧光PubMed IDs :
14769374 7517802 29680832
免疫印迹PubMed IDs :
23975820 3272160
其他信息 :
This is a very fragile IgM antibody. For optimum activity, we recommend these antibody products be kept at -20C or -80C either frozen in aliquots or with the addition of an equal volume of a cryoprotectant such as glycerol.
DSHB增长培养基 :
Iscove's
References (legacy) :
Neuron 1, 105-116.; Dev. Neurosci. 22, 154-166.; J. Comp. Neurol. 439, 368-383.; Cerebral Cortex 12, 617-624.; Science 297(5586), 1525-1531.; J. Biol. Chem. 288(4), 2623-2631.
公司信息
Developmental Studies Hybridoma Bank
University of Iowa
dshb@uiowa.edu
http://dshb.biology.uiowa.edu
公司总部: 美国
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构,为生命科学研究领域及诊断领域,提供高质量的抗体等产品。