产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
肌球蛋白重链, 禁食, 2X
目录 :
6H1
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
6H1
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-冰冻切片
文章摘录数: 39
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; 小鼠; 0.5 ug/ml; 图 2a
Bartoli F, Debant M, Chuntharpursat Bon E, Evans E, Musialowski K, Parsonage G, et al. Endothelial Piezo1 sustains muscle capillary density and contributes to physical activity. J Clin Invest. 2022;132: pubmed 出版商
  • 免疫组化; 小鼠
Steinert N, Potts G, Wilson G, Klamen A, Lin K, Hermanson J, et al. Mapping of the contraction-induced phosphoproteome identifies TRIM28 as a significant regulator of skeletal muscle size and function. Cell Rep. 2021;34:108796 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 图 6e
Seo J, Kang J, Kim Y, Jo Y, Kim J, Hann S, et al. Maintenance of type 2 glycolytic myofibers with age by Mib1-Actn3 axis. Nat Commun. 2021;12:1294 pubmed 出版商
  • 免疫组化; 大鼠; 1:1000; 图 2e
Perrin A, Metay C, Villanova M, Carlier R, Pegoraro E, Juntas Morales R, et al. A new congenital multicore titinopathy associated with fast myosin heavy chain deficiency. Ann Clin Transl Neurol. 2020;7:846-854 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3c
Koh J, Hancock C, Terada S, Higashida K, Holloszy J, Han D. PPARβ Is Essential for Maintaining Normal Levels of PGC-1α and Mitochondria and for the Increase in Muscle Mitochondria Induced by Exercise. Cell Metab. 2017;25:1176-1185.e5 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 1f
Cortez Toledo O, Schnair C, Sangngern P, Metzger D, Chao L. Nur77 deletion impairs muscle growth during developmental myogenesis and muscle regeneration in mice. PLoS ONE. 2017;12:e0171268 pubmed 出版商
  • 免疫组化; 人类; 1:25
St Jean Pelletier F, Pion C, Leduc Gaudet J, Sgarioto N, Zovilé I, Barbat Artigas S, et al. The impact of ageing, physical activity, and pre-frailty on skeletal muscle phenotype, mitochondrial content, and intramyocellular lipids in men. J Cachexia Sarcopenia Muscle. 2017;8:213-228 pubmed 出版商
  • 免疫组化; 小鼠; 1:2
Southard S, Kim J, Low S, Tsika R, Lepper C. Myofiber-specific TEAD1 overexpression drives satellite cell hyperplasia and counters pathological effects of dystrophin deficiency. elife. 2016;5: pubmed 出版商
  • 免疫组化; 人类; 图 1a
White S, McDermott M, Sufit R, Kosmac K, Bugg A, Gonzalez Freire M, et al. Walking performance is positively correlated to calf muscle fiber size in peripheral artery disease subjects, but fibers show aberrant mitophagy: an observational study. J Transl Med. 2016;14:284 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 1:25; 图 4a
Spendiff S, Vuda M, Gouspillou G, Aare S, Pérez A, Morais J, et al. Denervation drives mitochondrial dysfunction in skeletal muscle of octogenarians. J Physiol. 2016;594:7361-7379 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:25; 图 1
Aare S, Spendiff S, Vuda M, Elkrief D, Pérez A, Wu Q, et al. Failed reinnervation in aging skeletal muscle. Skelet Muscle. 2016;6:29 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:5; 图 5
Riaz M, Raz Y, van Putten M, Paniagua Soriano G, Krom Y, Florea B, et al. PABPN1-Dependent mRNA Processing Induces Muscle Wasting. PLoS Genet. 2016;12:e1006031 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 1:25; 图 1b
Power G, Minozzo F, Spendiff S, Filion M, Konokhova Y, Purves Smith M, et al. Reduction in single muscle fiber rate of force development with aging is not attenuated in world class older masters athletes. Am J Physiol Cell Physiol. 2016;310:C318-27 pubmed 出版商
  • 免疫组化; 小鼠; 图 1
Ebert S, Dyle M, Bullard S, Dierdorff J, Murry D, Fox D, et al. Identification and Small Molecule Inhibition of an Activating Transcription Factor 4 (ATF4)-dependent Pathway to Age-related Skeletal Muscle Weakness and Atrophy. J Biol Chem. 2015;290:25497-511 pubmed 出版商
  • 免疫组化; 人类
Walton R, Finlin B, Mula J, Long D, Zhu B, Fry C, et al. Insulin-resistant subjects have normal angiogenic response to aerobic exercise training in skeletal muscle, but not in adipose tissue. Physiol Rep. 2015;3: pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:600; 图 9
Seaberg B, Henslee G, Wang S, Paez Colasante X, Landreth G, Rimer M. Muscle-derived extracellular signal-regulated kinases 1 and 2 are required for the maintenance of adult myofibers and their neuromuscular junctions. Mol Cell Biol. 2015;35:1238-53 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 1
Tontonoz P, Cortez Toledo O, Wroblewski K, Hong C, Lim L, Carranza R, et al. The orphan nuclear receptor Nur77 is a determinant of myofiber size and muscle mass in mice. Mol Cell Biol. 2015;35:1125-38 pubmed 出版商
  • 免疫组化; 人类; 1:25
  • 免疫组化; 大鼠; 1:25
  • 免疫组化; 小鼠; 1:25
Gouspillou G, Sgarioto N, Norris B, Barbat Artigas S, Aubertin Leheudre M, Morais J, et al. The relationship between muscle fiber type-specific PGC-1α content and mitochondrial content varies between rodent models and humans. PLoS ONE. 2014;9:e103044 pubmed 出版商
  • 免疫组化; 人类
Fry C, Noehren B, Mula J, Ubele M, Westgate P, Kern P, et al. Fibre type-specific satellite cell response to aerobic training in sedentary adults. J Physiol. 2014;592:2625-35 pubmed 出版商
Carroll K, Bazyler C, Bernards J, Taber C, Stuart C, DeWeese B, et al. Skeletal Muscle Fiber Adaptations Following Resistance Training Using Repetition Maximums or Relative Intensity. Sports (Basel). 2019;7: pubmed 出版商
Sonjak V, Jacob K, Morais J, Rivera Zengotita M, Spendiff S, Spake C, et al. Fidelity of muscle fibre reinnervation modulates ageing muscle impact in elderly women. J Physiol. 2019;597:5009-5023 pubmed 出版商
Yao X, Yu T, Xi F, Xu Y, Ma L, Pan X, et al. BAMBI shuttling between cytosol and membrane is required for skeletal muscle development and regeneration. Biochem Biophys Res Commun. 2018;: pubmed 出版商
Sellers R, Mahmood S, Perumal G, Macaluso F, Kurland I. Phenotypic Modulation of Skeletal Muscle Fibers in LPIN1-Deficient Lipodystrophic ( fld) Mice. Vet Pathol. 2019;56:322-331 pubmed 出版商
Cullins M, Krekeler B, Connor N. Differential impact of tongue exercise on intrinsic lingual muscles. Laryngoscope. 2018;128:2245-2251 pubmed 出版商
Greschik H, Duteil D, Messaddeq N, Willmann D, Arrigoni L, Sum M, et al. The histone code reader Spin1 controls skeletal muscle development. Cell Death Dis. 2017;8:e3173 pubmed 出版商
Murgia M, Toniolo L, Nagaraj N, Ciciliot S, Vindigni V, Schiaffino S, et al. Single Muscle Fiber Proteomics Reveals Fiber-Type-Specific Features of Human Muscle Aging. Cell Rep. 2017;19:2396-2409 pubmed 出版商
Jarosch I, Gehlert S, Jacko D, Koczulla R, Wencker M, Welte T, et al. Different Training-Induced Skeletal Muscle Adaptations in COPD Patients with and without Alpha-1 Antitrypsin Deficiency. Respiration. 2016;92:339-347 pubmed
Morton R, Oikawa S, Wavell C, Mazara N, McGlory C, Quadrilatero J, et al. Neither load nor systemic hormones determine resistance training-mediated hypertrophy or strength gains in resistance-trained young men. J Appl Physiol (1985). 2016;121:129-38 pubmed 出版商
Khogali S, Lucas B, Ammar T, DeJong D, Barbalinardo M, Hayward L, et al. Physiological basis for muscle stiffness and weakness in a knock-in M1592V mouse model of hyperkalemic periodic paralysis. Physiol Rep. 2015;3: pubmed 出版商
Scribbans T, Ma J, Edgett B, Vorobej K, Mitchell A, Zelt J, et al. Resveratrol supplementation does not augment performance adaptations or fibre-type-specific responses to high-intensity interval training in humans. Appl Physiol Nutr Metab. 2014;39:1305-13 pubmed 出版商
Mouisel E, Relizani K, Mille Hamard L, Denis R, Hourd C, Agbulut O, et al. Myostatin is a key mediator between energy metabolism and endurance capacity of skeletal muscle. Am J Physiol Regul Integr Comp Physiol. 2014;307:R444-54 pubmed 出版商
Ellefsen S, Vikmoen O, Zacharoff E, Rauk I, Slettaløkken G, Hammarström D, et al. Reliable determination of training-induced alterations in muscle fiber composition in human skeletal muscle using quantitative polymerase chain reaction. Scand J Med Sci Sports. 2014;24:e332-42 pubmed 出版商
Scribbans T, Edgett B, Vorobej K, Mitchell A, Joanisse S, Matusiak J, et al. Fibre-specific responses to endurance and low volume high intensity interval training: striking similarities in acute and chronic adaptation. PLoS ONE. 2014;9:e98119 pubmed 出版商
Malfatti E, Lehtokari V, Böhm J, De Winter J, Schäffer U, Estournet B, et al. Muscle histopathology in nebulin-related nemaline myopathy: ultrastrastructural findings correlated to disease severity and genotype. Acta Neuropathol Commun. 2014;2:44 pubmed 出版商
Lucas B, Ammar T, Khogali S, DeJong D, Barbalinardo M, Nishi C, et al. Contractile abnormalities of mouse muscles expressing hyperkalemic periodic paralysis mutant NaV1.4 channels do not correlate with Na+ influx or channel content. Physiol Genomics. 2014;46:385-97 pubmed 出版商
Matthews C, Lovering R, Bowen T, Fishman P. Tetanus toxin preserves skeletal muscle contractile force and size during limb immobilization. Muscle Nerve. 2014;50:759-66 pubmed 出版商
Joanne P, Hourde C, Ochala J, Caudéran Y, Medja F, Vignaud A, et al. Impaired adaptive response to mechanical overloading in dystrophic skeletal muscle. PLoS ONE. 2012;7:e35346 pubmed 出版商
Rhee H, Steel C, Derksen F, Robinson N, Hoh J. Immunohistochemical analysis of laryngeal muscles in normal horses and horses with subclinical recurrent laryngeal neuropathy. J Histochem Cytochem. 2009;57:787-800 pubmed 出版商
Lucas C, Kang L, Hoh J. Monospecific antibodies against the three mammalian fast limb myosin heavy chains. Biochem Biophys Res Commun. 2000;272:303-8 pubmed
产品信息
内部号码 :
3315
名称 :
6H1
Depositor Name :
Lucas, C.
Depositor Institution :
University of Sydney
Date Deposited :
9/26/07
Allow Hybridoma Distribution :
No
Cells Available (legacy) :
No
抗原 :
肌球蛋白重链, 禁食, 2X
抗原物种 :
宿主物种 :
小鼠
抗体亚型 :
MIgM
Isotype for catalog (legacy) :
IgM, kappa light chain
Positive Tested Species Reactivity :
猫, 豚鼠, 人类, 小鼠, 兔, 大鼠
Species Tested (legacy) :
豚鼠, 大鼠, 小鼠, 兔, 猫, 人类骨骼肌, 马
Initial Publication Pubmed ID :
10872844
Depositor Notes (Special Instructions) :
This is a very fragile IgM antibody. For optimum activity, we recommend these antibody products be kept at -20C or -80C either frozen in aliquots or with the addition of an equal volume of a cryoprotectant such as glycerol.
Collections :
细胞骨架
搜索关键词 :
Lucas, Christine, Myosin heavy chain, fast, 2X, Rabbit, MIgM, Guinea Pig/Rat/Mouse/Rabbit/Feline/Human, MYH1, , AB_2314830, monoclonal
抗原分子量 :
~200 kDa
基因 :
MYH1
UniProt数据库编号 :
Q9TSE5
抗体登记处号码 :
AB_2314830
免疫原 :
Retractor bulbi (adult rabbit) crude muscle extract muscle co-absorbed with adjuvant peptide to gold particles as immunogen carrier.
克隆性 :
单克隆
Myeloma Strain :
NS-1
表位定位 :
No
Recommended Applications :
FFPE, 免疫荧光, 免疫组化, 免疫印迹
Immunoblotting (legacy) :
Yes
免疫组化PubMed IDs :
10872844 24714718 25121500 27686000 27687713 30381013 31368533
免疫荧光PubMed IDs :
24687582 24901767 25211703 24965795 24725366 24590678 29168801 29243257 30580997 28614723 31373325
免疫印迹PubMed IDs :
10872844 31373325
FFPE PubMed IDs :
24924099
PubMed IDs :
19398607
其他信息 :
6H1 has been successfully used to stain skeletal muscle paraffin sections. Low pH antigen retrieval and pre-treatment with Proteinase K is required. See PUBMED ID: 24924099.
DSHB增长培养基 :
Iscove's
References (legacy) :
Biochem. Biophys. Res. Commun. 272, 303-308.; Eur. J. Histochem. 52(3), 179-190.; J. Histochem & Cytochem. 57(8), 787-800.
公司信息
Developmental Studies Hybridoma Bank
University of Iowa
dshb@uiowa.edu
http://dshb.biology.uiowa.edu
公司总部: 美国
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构,为生命科学研究领域及诊断领域,提供高质量的抗体等产品。