产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
Podoplanin
目录 :
8.1.1
克隆性 :
单克隆
宿主 :
Syrian golden hamster
共轭标签 :
未共轭
克隆名称 :
8.1.1
反应物种 :
小鼠, fruit fly
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
文章摘录数: 67
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 3s2b
Zhang K, Yao E, Chen B, Chuang E, Wong J, Seed R, et al. Acquisition of cellular properties during alveolar formation requires differential activity and distribution of mitochondria. elife. 2022;11: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:500; 图 s2c
Wutschka J, Kast B, Sator Schmitt M, Appak Baskoy S, Hess J, Sinn H, et al. JUNB suppresses distant metastasis by influencing the initial metastatic stage. Clin Exp Metastasis. 2021;38:411-423 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 3f
Liberti D, Kremp M, Liberti W, Penkala I, Li S, Zhou S, et al. Alveolar epithelial cell fate is maintained in a spatially restricted manner to promote lung regeneration after acute injury. Cell Rep. 2021;35:109092 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 1s4b
Zhang K, Yao E, Lin C, Chou Y, Wong J, Li J, et al. A mammalian Wnt5a-Ror2-Vangl2 axis controls the cytoskeleton and confers cellular properties required for alveologenesis. elife. 2020;9: pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 1f
Ikonomou L, Herriges M, Lewandowski S, Marsland R, Villacorta Martin C, Caballero I, et al. The in vivo genetic program of murine primordial lung epithelial progenitors. Nat Commun. 2020;11:635 pubmed 出版商
  • 免疫组化; fruit fly ; 1:50; 图 2a
Zmojdzian M, de Joussineau S, Da Ponte J, Jagla K. Distinct subsets of Eve-positive pericardial cells stabilise cardiac outflow and contribute to Hox gene-triggered heart morphogenesis in Drosophila. Development. 2018;145: pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:20; 图 2a
Guo H, Kazadaeva Y, Ortega F, Manjunath N, Desai T. Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung. Dev Biol. 2017;430:214-223 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 2d
Lin C, Yao E, Zhang K, Jiang X, Croll S, Thompson Peer K, et al. YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis. elife. 2017;6: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 4b
Weeden C, Chen Y, Ma S, Hu Y, Ramm G, Sutherland K, et al. Lung Basal Stem Cells Rapidly Repair DNA Damage Using the Error-Prone Nonhomologous End-Joining Pathway. PLoS Biol. 2017;15:e2000731 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 1h
Kechele D, Blue R, Zwarycz B, Espenschied S, Mah A, Siegel M, et al. Orphan Gpr182 suppresses ERK-mediated intestinal proliferation during regeneration and adenoma formation. J Clin Invest. 2017;127:593-607 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:50; 图 e1d
Nonomura K, Woo S, Chang R, Gillich A, Qiu Z, Francisco A, et al. Piezo2 senses airway stretch and mediates lung inflation-induced apnoea. Nature. 2017;541:176-181 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 4
Laresgoiti U, Nikolić M, Rao C, Brady J, Richardson R, Batchen E, et al. Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate. Development. 2016;143:3686-3699 pubmed
  • 免疫组化-冰冻切片; 小鼠; 图 1d
Karaman S, Hollmén M, Yoon S, Alkan H, Alitalo K, Wolfrum C, et al. Transgenic overexpression of VEGF-C induces weight gain and insulin resistance in mice. Sci Rep. 2016;6:31566 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 s7c
Crosswhite P, Podsiadlowska J, Curtis C, Gao S, Xia L, Srinivasan R, et al. CHD4-regulated plasmin activation impacts lymphovenous hemostasis and hepatic vascular integrity. J Clin Invest. 2016;126:2254-66 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 3aa
San Agustin J, Klena N, Granath K, Panigrahy A, Stewart E, Devine W, et al. Genetic link between renal birth defects and congenital heart disease. Nat Commun. 2016;7:11103 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 3
Gao L, Jiang Y, Mu L, Liu Y, Wang F, Wang P, et al. Efficient Generation of Mice with Consistent Transgene Expression by FEEST. Sci Rep. 2015;5:16284 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1g
Sun L, Sun C, Liang Z, Li H, Chen L, Luo H, et al. FSP1(+) fibroblast subpopulation is essential for the maintenance and regeneration of medullary thymic epithelial cells. Sci Rep. 2015;5:14871 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:500
Rouhani S, Eccles J, Riccardi P, Peske J, Tewalt E, Cohen J, et al. Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance induction. Nat Commun. 2015;6:6771 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 5 ug/ml; 图 s7
Ngo J, Matsuyama M, Kim C, Poventud Fuentes I, Bates A, Siedlak S, et al. Bax deficiency extends the survival of Ku70 knockout mice that develop lung and heart diseases. Cell Death Dis. 2015;6:e1706 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:250; 图 6
Plosa E, Young L, Gulleman P, Polosukhin V, Zaynagetdinov R, Benjamin J, et al. Epithelial β1 integrin is required for lung branching morphogenesis and alveolarization. Development. 2014;141:4751-62 pubmed 出版商
Katsura H, Kobayashi Y, Tata P, Hogan B. IL-1 and TNFα Contribute to the Inflammatory Niche to Enhance Alveolar Regeneration. Stem Cell Reports. 2019;12:657-666 pubmed 出版商
Frye M, Taddei A, Dierkes C, Martínez Corral I, Fielden M, Ortsäter H, et al. Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program. Nat Commun. 2018;9:1511 pubmed 出版商
Turner V, Mabbott N. Structural and functional changes to lymph nodes in ageing mice. Immunology. 2017;151:239-247 pubmed 出版商
Liang J, Zhang Y, Xie T, Liu N, Chen H, Geng Y, et al. Hyaluronan and TLR4 promote surfactant-protein-C-positive alveolar progenitor cell renewal and prevent severe pulmonary fibrosis in mice. Nat Med. 2016;22:1285-1293 pubmed 出版商
Clark J, O keefe A, Mastracci T, Sussel L, Matise M, Kucenas S. Mammalian Nkx2.2+ perineurial glia are essential for motor nerve development. Dev Dyn. 2014;243:1116-29 pubmed 出版商
Guo Y, Mishra A, Weng T, Chintagari N, Wang Y, Zhao C, et al. Wnt3a mitigates acute lung injury by reducing P2X7 receptor-mediated alveolar epithelial type I cell death. Cell Death Dis. 2014;5:e1286 pubmed 出版商
Alanis D, Chang D, Akiyama H, Krasnow M, Chen J. Two nested developmental waves demarcate a compartment boundary in the mouse lung. Nat Commun. 2014;5:3923 pubmed 出版商
Blum K, Karaman S, Proulx S, Ochsenbein A, Luciani P, Leroux J, et al. Chronic high-fat diet impairs collecting lymphatic vessel function in mice. PLoS ONE. 2014;9:e94713 pubmed 出版商
Zgraggen S, Huggenberger R, Kerl K, Detmar M. An important role of the SDF-1/CXCR4 axis in chronic skin inflammation. PLoS ONE. 2014;9:e93665 pubmed 出版商
Turcatel G, Rubin N, Menke D, Martin G, Shi W, Warburton D. Lung mesenchymal expression of Sox9 plays a critical role in tracheal development. BMC Biol. 2013;11:117 pubmed 出版商
Johnson L, Jackson D. The chemokine CX3CL1 promotes trafficking of dendritic cells through inflamed lymphatics. J Cell Sci. 2013;126:5259-70 pubmed 出版商
Herzog B, Fu J, Wilson S, Hess P, Sen A, McDaniel J, et al. Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2. Nature. 2013;502:105-9 pubmed 出版商
Iolyeva M, Aebischer D, Proulx S, Willrodt A, Ecoiffier T, Häner S, et al. Interleukin-7 is produced by afferent lymphatic vessels and supports lymphatic drainage. Blood. 2013;122:2271-81 pubmed 出版商
Majima T, Takeuchi K, Sano K, Hirashima M, Zankov D, Tanaka Okamoto M, et al. An Adaptor Molecule Afadin Regulates Lymphangiogenesis by Modulating RhoA Activity in the Developing Mouse Embryo. PLoS ONE. 2013;8:e68134 pubmed 出版商
Figueira R, Watson K, Holden D, Helaine S. Identification of salmonella pathogenicity island-2 type III secretion system effectors involved in intramacrophage replication of S. enterica serovar typhimurium: implications for rational vaccine design. MBio. 2013;4:e00065 pubmed 出版商
Takekoshi T, Fang L, Paragh G, Hwang S. CCR7-expressing B16 melanoma cells downregulate interferon-?-mediated inflammation and increase lymphangiogenesis in the tumor microenvironment. Oncogenesis. 2012;1:e9 pubmed 出版商
Krishnan H, Ochoa Alvarez J, Shen Y, Nevel E, Lakshminarayanan M, Williams M, et al. Serines in the intracellular tail of podoplanin (PDPN) regulate cell motility. J Biol Chem. 2013;288:12215-21 pubmed 出版商
Nechiporuk T, Klezovitch O, Nguyen L, Vasioukhin V. Dlg5 maintains apical aPKC and regulates progenitor differentiation during lung morphogenesis. Dev Biol. 2013;377:375-84 pubmed 出版商
Iolyeva M, Karaman S, Willrodt A, Weingartner S, Vigl B, Halin C. Novel role for ALCAM in lymphatic network formation and function. FASEB J. 2013;27:978-90 pubmed 出版商
Betterman K, Paquet Fifield S, Asselin Labat M, Visvader J, Butler L, Stacker S, et al. Remodeling of the lymphatic vasculature during mouse mammary gland morphogenesis is mediated via epithelial-derived lymphangiogenic stimuli. Am J Pathol. 2012;181:2225-38 pubmed 出版商
Arora R, Metzger R, Papaioannou V. Multiple roles and interactions of Tbx4 and Tbx5 in development of the respiratory system. PLoS Genet. 2012;8:e1002866 pubmed 出版商
Ochoa Alvarez J, Krishnan H, Shen Y, Acharya N, Han M, McNulty D, et al. Plant lectin can target receptors containing sialic acid, exemplified by podoplanin, to inhibit transformed cell growth and migration. PLoS ONE. 2012;7:e41845 pubmed 出版商
Larrieu Lahargue F, Welm A, Bouchecareilh M, Alitalo K, Li D, Bikfalvi A, et al. Blocking Fibroblast Growth Factor receptor signaling inhibits tumor growth, lymphangiogenesis, and metastasis. PLoS ONE. 2012;7:e39540 pubmed 出版商
Fletcher A, Malhotra D, Acton S, Lukacs Kornek V, Bellemare Pelletier A, Curry M, et al. Reproducible isolation of lymph node stromal cells reveals site-dependent differences in fibroblastic reticular cells. Front Immunol. 2011;2:35 pubmed 出版商
Tan K, Yeo K, Wong F, Lim H, Khoo K, Abastado J, et al. Expansion of cortical and medullary sinuses restrains lymph node hypertrophy during prolonged inflammation. J Immunol. 2012;188:4065-80 pubmed 出版商
Hashimoto S, Chen H, Que J, Brockway B, Drake J, Snyder J, et al. ?-Catenin-SOX2 signaling regulates the fate of developing airway epithelium. J Cell Sci. 2012;125:932-42 pubmed 出版商
Rosser J, Bonewald L. Studying osteocyte function using the cell lines MLO-Y4 and MLO-A5. Methods Mol Biol. 2012;816:67-81 pubmed 出版商
Rygiel T, Karnam G, Goverse G, van der Marel A, Greuter M, van Schaarenburg R, et al. CD200-CD200R signaling suppresses anti-tumor responses independently of CD200 expression on the tumor. Oncogene. 2012;31:2979-88 pubmed 出版商
Porter J, Bukey B, Geyer A, Willnauer C, Reynolds P. Immunohistochemical detection and regulation of ?5 nicotinic acetylcholine receptor (nAChR) subunits by FoxA2 during mouse lung organogenesis. Respir Res. 2011;12:82 pubmed 出版商
Habermehl D, Parkitna J, Kaden S, Brugger B, Wieland F, Grone H, et al. Glucocorticoid activity during lung maturation is essential in mesenchymal and less in alveolar epithelial cells. Mol Endocrinol. 2011;25:1280-8 pubmed 出版商
Rock J, Gao X, Xue Y, Randell S, Kong Y, Hogan B. Notch-dependent differentiation of adult airway basal stem cells. Cell Stem Cell. 2011;8:639-48 pubmed 出版商
Vigl B, Aebischer D, Nitschké M, Iolyeva M, Röthlin T, Antsiferova O, et al. Tissue inflammation modulates gene expression of lymphatic endothelial cells and dendritic cell migration in a stimulus-dependent manner. Blood. 2011;118:205-15 pubmed 出版商
Lv H, Havari E, Pinto S, Gottumukkala R, Cornivelli L, Raddassi K, et al. Impaired thymic tolerance to ?-myosin directs autoimmunity to the heart in mice and humans. J Clin Invest. 2011;121:1561-73 pubmed 出版商
Link A, Hardie D, Favre S, Britschgi M, Adams D, Sixt M, et al. Association of T-zone reticular networks and conduits with ectopic lymphoid tissues in mice and humans. Am J Pathol. 2011;178:1662-75 pubmed 出版商
De Paepe M, Mao Q, Ghanta S, Hovanesian V, Padbury J. Alveolar epithelial cell therapy with human cord blood-derived hematopoietic progenitor cells. Am J Pathol. 2011;178:1329-39 pubmed 出版商
Tompkins D, Besnard V, Lange A, Keiser A, Wert S, Bruno M, et al. Sox2 activates cell proliferation and differentiation in the respiratory epithelium. Am J Respir Cell Mol Biol. 2011;45:101-10 pubmed 出版商
Shalapour S, Deiser K, Sercan O, Tuckermann J, Minnich K, Willimsky G, et al. Commensal microflora and interferon-gamma promote steady-state interleukin-7 production in vivo. Eur J Immunol. 2010;40:2391-400 pubmed 出版商
Jurisic G, Iolyeva M, Proulx S, Halin C, Detmar M. Thymus cell antigen 1 (Thy1, CD90) is expressed by lymphatic vessels and mediates cell adhesion to lymphatic endothelium. Exp Cell Res. 2010;316:2982-92 pubmed 出版商
Pedrioli D, Karpanen T, Dabouras V, Jurisic G, van de Hoek G, Shin J, et al. miR-31 functions as a negative regulator of lymphatic vascular lineage-specific differentiation in vitro and vascular development in vivo. Mol Cell Biol. 2010;30:3620-34 pubmed 出版商
Larrieu Lahargue F, Welm A, Thomas K, Li D. Netrin-4 induces lymphangiogenesis in vivo. Blood. 2010;115:5418-26 pubmed 出版商
Cohen J, Guidi C, Tewalt E, Qiao H, Rouhani S, Ruddell A, et al. Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation. J Exp Med. 2010;207:681-8 pubmed 出版商
Fletcher A, Lukacs Kornek V, Reynoso E, Pinner S, Bellemare Pelletier A, Curry M, et al. Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions. J Exp Med. 2010;207:689-97 pubmed 出版商
Tzeng T, Chyou S, Tian S, Webster B, Carpenter A, Guaiquil V, et al. CD11c(hi) dendritic cells regulate the re-establishment of vascular quiescence and stabilization after immune stimulation of lymph nodes. J Immunol. 2010;184:4247-57 pubmed 出版商
Koo B, Coe D, Dixon L, Somerville R, Nelson C, Wang L, et al. ADAMTS9 is a cell-autonomously acting, anti-angiogenic metalloprotease expressed by microvascular endothelial cells. Am J Pathol. 2010;176:1494-504 pubmed 出版商
Johnson L, Clasper S, Holt A, Lalor P, Baban D, Jackson D. An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium. J Exp Med. 2006;203:2763-77 pubmed
Farr A, Berry M, Kim A, Nelson A, Welch M, Aruffo A. Characterization and cloning of a novel glycoprotein expressed by stromal cells in T-dependent areas of peripheral lymphoid tissues. J Exp Med. 1992;176:1477-82 pubmed
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产品信息
内部号码 :
3025
名称 :
8.1.1
Depositor Name :
Farr, A.G .
Depositor Institution :
University of Washington
Date Deposited :
6/7/01
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
抗原 :
Podoplanin
抗原物种 :
小鼠
宿主物种 :
Syrian hamster
抗体亚型 :
Syrian Hamster IgG
Isotype for catalog (legacy) :
IgG
Positive Tested Species Reactivity :
小鼠
Species Tested (legacy) :
mouse-other species not tested
Initial Publication Pubmed ID :
1402691
Depositor Notes (Special Instructions) :
Reacts with T1 alpha in the lung, podoplanin in the kidney, and lymphatic endothelium; Recognizes aggrus/podoplanin expressed by platelets; Stains formalin-fixed paraffin embedded samples.
Collections :
CD抗原, 细胞标记
搜索关键词 :
Farr, Andrew G, Podoplanin, Mouse, Syrian Hamster IgG, Mouse, Pdpn, Gp38; OTS-8; T1alpha; RANDAM-2; T1-alpha, AB_531893, monoclonal
抗原分子量 :
38 kDa (36-40 kDa)
基因 :
Pdpn
Alternate Gene Name(s) :
Gp38;OTS-8;T1alpha;RANDAM-2;T1甲
UniProt数据库编号 :
Q62011
抗体登记处号码 :
AB_531893
Synonyms (Alternate Clone Names) :
glycoprotein, 38 kDa, mucin-like
免疫原 :
Thymic stromal cell line E-71 (murine).
克隆性 :
单克隆
Myeloma Strain :
P3x
表位定位 :
No
Epitope Location or Sequence :
细胞外区域
Recommended Applications :
流式细胞仪, 免疫荧光, 免疫组化, 免疫印迹
Immunoblotting (legacy) :
Yes
免疫组化PubMed IDs :
1374092 24979729 24714646 20599951 21624809 22430738 22761819 22844530 23552640 21659474 20093484 21682884 22421361 20231692 24274029 22876201
免疫荧光PubMed IDs :
24979729 24714646 24695674 25395457 24879355 20599951 21624809 23466739 23995678 21356383 22430738 20855650 24006262 22761819 20407033 22020332 20690180 22421361 23840823 24274029 21435450 22566825 23063660 27694932 29666442 27002738
免疫印迹PubMed IDs :
1374092 24922070 22130923 23466739 23995678 23530051 22844530
流式细胞仪PubMed IDs :
1374092 20599951 21596851 20308365 20308362 22430738 23592259 20479124 21436590 23963040 23169771 22566825
DSHB增长培养基 :
Iscove's
References (legacy) :
J. Exp. Med. 176, 1477-1482.; J. Histochem. Cytochem. 40(5), 651-664.; Dev. Biol. 167(1), 294-306.; Development 128, 5181-5188.: EMBO J. 22(14), 3546-3556.; Am. J. Physiol. Lung Cell. Mol. Physiol. 290, 32-40.; Cancer Cell 9, 261-272. doi:10.1016/j.ccr.2006.03.10
公司信息
Developmental Studies Hybridoma Bank
University of Iowa
dshb@uiowa.edu
http://dshb.biology.uiowa.edu
公司总部: 美国
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构,为生命科学研究领域及诊断领域,提供高质量的抗体等产品。