产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
异染色质蛋白1
目录 :
C1A9
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
C1A9
反应物种 :
果蝇
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀
, proximity ligation assay
文章摘录数: 43
出版应用/物种/样本/稀释 | 参考文献 |
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Brueckner L, van Arensbergen J, Akhtar W, Pagie L, van Steensel B. High-throughput assessment of context-dependent effects of chromatin proteins. Epigenetics Chromatin. 2016;9:43 pubmed
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Marr S, Lis J, Treisman J, Marr M. The metazoan-specific mediator subunit 26 (Med26) is essential for viability and is found at both active genes and pericentric heterochromatin in Drosophila melanogaster. Mol Cell Biol. 2014;34:2710-20 pubmed
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Jiang N, Du G, Tobias E, Wood J, Whitaker R, Neretti N, et al. Dietary and genetic effects on age-related loss of gene silencing reveal epigenetic plasticity of chromatin repression during aging. Aging (Albany NY). 2013;5:813-24 pubmed
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Smith E, Lee M, Winter B, Droz N, Eissenberg J, Shiekhattar R, et al. Drosophila UTX is a histone H3 Lys27 demethylase that colocalizes with the elongating form of RNA polymerase II. Mol Cell Biol. 2008;28:1041-6 pubmed
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Bongiorni S, Pasqualini B, Taranta M, Singh P, Prantera G. Epigenetic regulation of facultative heterochromatinisation in Planococcus citri via the Me(3)K9H3-HP1-Me(3)K20H4 pathway. J Cell Sci. 2007;120:1072-80 pubmed
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Shi S, Calhoun H, Xia F, Li J, Le L, Li W. JAK signaling globally counteracts heterochromatic gene silencing. Nat Genet. 2006;38:1071-6 pubmed
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Liu L, Ni J, Shi Y, Oakeley E, Sun F. Sex-specific role of Drosophila melanogaster HP1 in regulating chromatin structure and gene transcription. Nat Genet. 2005;37:1361-6 pubmed
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De Lucia F, Ni J, Vaillant C, Sun F. HP1 modulates the transcription of cell-cycle regulators in Drosophila melanogaster. Nucleic Acids Res. 2005;33:2852-8 pubmed
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Cryderman D, Grade S, Li Y, Fanti L, Pimpinelli S, Wallrath L. Role of Drosophila HP1 in euchromatic gene expression. Dev Dyn. 2005;232:767-74 pubmed
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Perrini B, Piacentini L, Fanti L, Altieri F, Chichiarelli S, Berloco M, et al. HP1 controls telomere capping, telomere elongation, and telomere silencing by two different mechanisms in Drosophila. Mol Cell. 2004;15:467-76 pubmed
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Piacentini L, Fanti L, Berloco M, Perrini B, Pimpinelli S. Heterochromatin protein 1 (HP1) is associated with induced gene expression in Drosophila euchromatin. J Cell Biol. 2003;161:707-14 pubmed
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Fanti L, Berloco M, Piacentini L, Pimpinelli S. Chromosomal distribution of heterochromatin protein 1 (HP1) in Drosophila: a cytological map of euchromatic HP1 binding sites. Genetica. 2003;117:135-47 pubmed
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Cenci G, Siriaco G, Raffa G, Kellum R, Gatti M. The Drosophila HOAP protein is required for telomere capping. Nat Cell Biol. 2003;5:82-4 pubmed
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Fanti L, Giovinazzo G, Berloco M, Pimpinelli S. The heterochromatin protein 1 prevents telomere fusions in Drosophila. Mol Cell. 1998;2:527-38 pubmed
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Cléard F, Delattre M, Spierer P. SU(VAR)3-7, a Drosophila heterochromatin-associated protein and companion of HP1 in the genomic silencing of position-effect variegation. EMBO J. 1997;16:5280-8 pubmed
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Platero J, Hartnett T, Eissenberg J. Functional analysis of the chromo domain of HP1. EMBO J. 1995;14:3977-86 pubmed
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James T, Elgin S. Identification of a nonhistone chromosomal protein associated with heterochromatin in Drosophila melanogaster and its gene. Mol Cell Biol. 1986;6:3862-72 pubmed
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产品信息
内部号码 :
909
名称 :
C1A9
Depositor Name :
Wallrath, L.L.
Depositor Institution :
University of Iowa
Date Deposited :
1/4/02
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
抗原 :
异染色质蛋白1
抗原物种 :
黑腹果蝇
宿主物种 :
小鼠
抗体亚型 :
MIgG1, kappa light chain
Isotype for catalog (legacy) :
IgG1, kappa light chain
Positive Tested Species Reactivity :
Drosophila,Planococcus citri
Species Tested (legacy) :
果蝇
Initial Publication Pubmed ID :
3099166
Depositor Notes (Special Instructions) :
detects HP1, a structural component of heterochromatin, on fixed squashed and whole mount Drosophila melanogaster salivary gland polytene chromosomes
Collections :
Drosophila antigens,Nucleus
搜索关键词 :
Wallrath, L.L., Heterochromatin Protein 1, Drosophila melanogaster, MIgG1, kappa light chain, Drosophila/Planococcus citri, Su(var)205, HP1, CG8409, AB_528276, Monoclonal, Drosophila antigens/Nucleus, Immunofluorescence/Western Blot/Immunoprecipitation/Chromatin Immunoprecipitation
抗原分子量 :
Predicted: 23 kDa; Apparent 24 kDa
基因 :
Su(var)205
Alternate Gene Name(s) :
HP1, CG8409
UniProt数据库编号 :
P05205
抗体登记处号码 :
AB_528276
免疫原 :
Nuclear proteins extracted in 2.0 M potassium thiocyanate
免疫原序列 :
总数蛋白
克隆性 :
单克隆
Myeloma Strain :
Sp2/0 Ag14
表位定位 :
No
Recommended Applications :
染色质免疫沉淀
, 免疫荧光, 免疫沉淀, 免疫印迹
Immunoblotting (legacy) :
Yes
免疫组化PubMed IDs :
27687497
免疫荧光PubMed IDs :
3099166 9311988 9844626 12723693 16258543 7664737 16892059 12756231 15304225 15704177 17327272 18344984 24820420 19584931 20961390 22291607 18039863 30389853
免疫印迹PubMed IDs :
3099166 27687497 9311988 12510197 16258543 16892059 12756231 15304225 18344984 15905474 24820420 22291607
免疫沉淀PubMed IDs :
19798443 19584931
染色质免疫沉淀
PubMed IDs :
12756231 18344984 20961390 22291607
DSHB增长培养基 :
RPMI
References (legacy) :
Mol. Cell. Biol. 6, 3862-3872.; Proc. Natl. Acad. Sci. USA 87, 9923-9927.
公司信息
Developmental Studies Hybridoma Bank
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构,为生命科学研究领域及诊断领域,提供高质量的抗体等产品。