产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
异染色质蛋白1
目录 :
C1A9
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
C1A9
反应物种 :
果蝇
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , proximity ligation assay
文章摘录数: 43
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 果蝇; 1:500; 图 5-s1
Swenson J, Colmenares S, Strom A, Costes S, Karpen G. The composition and organization of Drosophila heterochromatin are heterogeneous and dynamic. elife. 2016;5: pubmed 出版商
  • proximity ligation assay; 果蝇; 图 4
  • 免疫沉淀; 果蝇; 图 2
  • 免疫细胞化学; 果蝇; 图 1
  • 免疫印迹; 果蝇; 图 6
Eberle A, Jordán Pla A, Gañez Zapater A, Hessle V, Silberberg G, von Euler A, et al. An Interaction between RRP6 and SU(VAR)3-9 Targets RRP6 to Heterochromatin and Contributes to Heterochromatin Maintenance in Drosophila melanogaster. PLoS Genet. 2015;11:e1005523 pubmed 出版商
  • 免疫细胞化学; 果蝇; 1:10; 图 7
Cenci G, Ciapponi L, Marzullo M, Raffa G, Morciano P, Raimondo D, et al. The Analysis of Pendolino (peo) Mutants Reveals Differences in the Fusigenic Potential among Drosophila Telomeres. PLoS Genet. 2015;11:e1005260 pubmed 出版商
Brueckner L, van Arensbergen J, Akhtar W, Pagie L, van Steensel B. High-throughput assessment of context-dependent effects of chromatin proteins. Epigenetics Chromatin. 2016;9:43 pubmed
Hong S, Choi K. Antagonistic roles of Drosophila Tctp and Brahma in chromatin remodelling and stabilizing repeated sequences. Nat Commun. 2016;7:12988 pubmed 出版商
Wang C, Sun H, Zou R, Zhou T, Wang S, Sun S, et al. MDC1 functionally identified as an androgen receptor co-activator participates in suppression of prostate cancer. Nucleic Acids Res. 2015;43:4893-908 pubmed 出版商
López Falcón B, Meyer Nava S, Hernández Rodríguez B, Campos A, Montero D, Rudiño E, et al. Characterization of the Drosophila group ortholog to the amino-terminus of the alpha-thalassemia and mental retardation X-Linked (ATRX) vertebrate protein. PLoS ONE. 2014;9:e113182 pubmed 出版商
Xu N, Emelyanov A, Fyodorov D, Skoultchi A. Drosophila linker histone H1 coordinates STAT-dependent organization of heterochromatin and suppresses tumorigenesis caused by hyperactive JAK-STAT signaling. Epigenetics Chromatin. 2014;7:16 pubmed 出版商
Marr S, Lis J, Treisman J, Marr M. The metazoan-specific mediator subunit 26 (Med26) is essential for viability and is found at both active genes and pericentric heterochromatin in Drosophila melanogaster. Mol Cell Biol. 2014;34:2710-20 pubmed
Basquin D, Spierer A, Begeot F, Koryakov D, Todeschini A, Ronsseray S, et al. The Drosophila Su(var)3-7 gene is required for oogenesis and female fertility, genetically interacts with piwi and aubergine, but impacts only weakly transposon silencing. PLoS ONE. 2014;9:e96802 pubmed 出版商
Dufourt J, Dennis C, Boivin A, Gueguen N, Théron E, Goriaux C, et al. Spatio-temporal requirements for transposable element piRNA-mediated silencing during Drosophila oogenesis. Nucleic Acids Res. 2014;42:2512-24 pubmed 出版商
Jiang N, Du G, Tobias E, Wood J, Whitaker R, Neretti N, et al. Dietary and genetic effects on age-related loss of gene silencing reveal epigenetic plasticity of chromatin repression during aging. Aging (Albany NY). 2013;5:813-24 pubmed
Schoborg T, Rickels R, Barrios J, Labrador M. Chromatin insulator bodies are nuclear structures that form in response to osmotic stress and cell death. J Cell Biol. 2013;202:261-76 pubmed 出版商
Herzog S, Nagarkar Jaiswal S, Urban E, Riemer A, Fischer S, Heidmann S. Functional dissection of the Drosophila melanogaster condensin subunit Cap-G reveals its exclusive association with condensin I. PLoS Genet. 2013;9:e1003463 pubmed 出版商
Bugga L, McDaniel I, Engie L, Armstrong J. The Drosophila melanogaster CHD1 chromatin remodeling factor modulates global chromosome structure and counteracts HP1a and H3K9me2. PLoS ONE. 2013;8:e59496 pubmed 出版商
Sienski G, Donertas D, Brennecke J. Transcriptional silencing of transposons by Piwi and maelstrom and its impact on chromatin state and gene expression. Cell. 2012;151:964-80 pubmed 出版商
Maheshwari S, Barbash D. Cis-by-Trans regulatory divergence causes the asymmetric lethal effects of an ancestral hybrid incompatibility gene. PLoS Genet. 2012;8:e1002597 pubmed 出版商
Larson K, Yan S, Tsurumi A, Liu J, Zhou J, Gaur K, et al. Heterochromatin formation promotes longevity and represses ribosomal RNA synthesis. PLoS Genet. 2012;8:e1002473 pubmed 出版商
Dronamraju R, Mason J. MU2 and HP1a regulate the recognition of double strand breaks in Drosophila melanogaster. PLoS ONE. 2011;6:e25439 pubmed 出版商
Dufourt J, Brasset E, Desset S, Pouchin P, Vaury C. Polycomb group-dependent, heterochromatin protein 1-independent, chromatin structures silence retrotransposons in somatic tissues outside ovaries. DNA Res. 2011;18:451-61 pubmed 出版商
Wood J, Hillenmeyer S, Lawrence C, Chang C, Hosier S, Lightfoot W, et al. Chromatin remodeling in the aging genome of Drosophila. Aging Cell. 2010;9:971-8 pubmed 出版商
Sharakhova M, George P, Brusentsova I, Leman S, Bailey J, Smith C, et al. Genome mapping and characterization of the Anopheles gambiae heterochromatin. BMC Genomics. 2010;11:459 pubmed 出版商
Moshkovich N, Lei E. HP1 recruitment in the absence of argonaute proteins in Drosophila. PLoS Genet. 2010;6:e1000880 pubmed 出版商
Salzler H, Davidson J, Montgomery N, Duronio R. Loss of the histone pre-mRNA processing factor stem-loop binding protein in Drosophila causes genomic instability and impaired cellular proliferation. PLoS ONE. 2009;4:e8168 pubmed 出版商
Piacentini L, Fanti L, Negri R, Del Vescovo V, Fatica A, Altieri F, et al. Heterochromatin protein 1 (HP1a) positively regulates euchromatic gene expression through RNA transcript association and interaction with hnRNPs in Drosophila. PLoS Genet. 2009;5:e1000670 pubmed 出版商
Koch C, Honemann Capito M, Egger Adam D, Wodarz A. Windei, the Drosophila homolog of mAM/MCAF1, is an essential cofactor of the H3K9 methyl transferase dSETDB1/Eggless in germ line development. PLoS Genet. 2009;5:e1000644 pubmed 出版商
Gracheva E, Dus M, Elgin S. Drosophila RISC component VIG and its homolog Vig2 impact heterochromatin formation. PLoS ONE. 2009;4:e6182 pubmed 出版商
Cakouros D, Mills K, Denton D, Paterson A, Daish T, Kumar S. dLKR/SDH regulates hormone-mediated histone arginine methylation and transcription of cell death genes. J Cell Biol. 2008;182:481-95 pubmed 出版商
Shi S, Larson K, Guo D, Lim S, Dutta P, Yan S, et al. Drosophila STAT is required for directly maintaining HP1 localization and heterochromatin stability. Nat Cell Biol. 2008;10:489-96 pubmed 出版商
Smith E, Lee M, Winter B, Droz N, Eissenberg J, Shiekhattar R, et al. Drosophila UTX is a histone H3 Lys27 demethylase that colocalizes with the elongating form of RNA polymerase II. Mol Cell Biol. 2008;28:1041-6 pubmed
Bongiorni S, Pasqualini B, Taranta M, Singh P, Prantera G. Epigenetic regulation of facultative heterochromatinisation in Planococcus citri via the Me(3)K9H3-HP1-Me(3)K20H4 pathway. J Cell Sci. 2007;120:1072-80 pubmed
Shi S, Calhoun H, Xia F, Li J, Le L, Li W. JAK signaling globally counteracts heterochromatic gene silencing. Nat Genet. 2006;38:1071-6 pubmed
Liu L, Ni J, Shi Y, Oakeley E, Sun F. Sex-specific role of Drosophila melanogaster HP1 in regulating chromatin structure and gene transcription. Nat Genet. 2005;37:1361-6 pubmed
De Lucia F, Ni J, Vaillant C, Sun F. HP1 modulates the transcription of cell-cycle regulators in Drosophila melanogaster. Nucleic Acids Res. 2005;33:2852-8 pubmed
Cryderman D, Grade S, Li Y, Fanti L, Pimpinelli S, Wallrath L. Role of Drosophila HP1 in euchromatic gene expression. Dev Dyn. 2005;232:767-74 pubmed
Perrini B, Piacentini L, Fanti L, Altieri F, Chichiarelli S, Berloco M, et al. HP1 controls telomere capping, telomere elongation, and telomere silencing by two different mechanisms in Drosophila. Mol Cell. 2004;15:467-76 pubmed
Piacentini L, Fanti L, Berloco M, Perrini B, Pimpinelli S. Heterochromatin protein 1 (HP1) is associated with induced gene expression in Drosophila euchromatin. J Cell Biol. 2003;161:707-14 pubmed
Fanti L, Berloco M, Piacentini L, Pimpinelli S. Chromosomal distribution of heterochromatin protein 1 (HP1) in Drosophila: a cytological map of euchromatic HP1 binding sites. Genetica. 2003;117:135-47 pubmed
Cenci G, Siriaco G, Raffa G, Kellum R, Gatti M. The Drosophila HOAP protein is required for telomere capping. Nat Cell Biol. 2003;5:82-4 pubmed
Fanti L, Giovinazzo G, Berloco M, Pimpinelli S. The heterochromatin protein 1 prevents telomere fusions in Drosophila. Mol Cell. 1998;2:527-38 pubmed
Cléard F, Delattre M, Spierer P. SU(VAR)3-7, a Drosophila heterochromatin-associated protein and companion of HP1 in the genomic silencing of position-effect variegation. EMBO J. 1997;16:5280-8 pubmed
Platero J, Hartnett T, Eissenberg J. Functional analysis of the chromo domain of HP1. EMBO J. 1995;14:3977-86 pubmed
James T, Elgin S. Identification of a nonhistone chromosomal protein associated with heterochromatin in Drosophila melanogaster and its gene. Mol Cell Biol. 1986;6:3862-72 pubmed
产品信息
内部号码 :
909
名称 :
C1A9
Depositor Name :
Wallrath, L.L.
Depositor Institution :
University of Iowa
Date Deposited :
1/4/02
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
抗原 :
异染色质蛋白1
抗原物种 :
黑腹果蝇
宿主物种 :
小鼠
抗体亚型 :
MIgG1, kappa light chain
Isotype for catalog (legacy) :
IgG1, kappa light chain
Positive Tested Species Reactivity :
Drosophila,Planococcus citri
Species Tested (legacy) :
果蝇
Initial Publication Pubmed ID :
3099166
Depositor Notes (Special Instructions) :
detects HP1, a structural component of heterochromatin, on fixed squashed and whole mount Drosophila melanogaster salivary gland polytene chromosomes
Collections :
Drosophila antigens,Nucleus
搜索关键词 :
Wallrath, L.L., Heterochromatin Protein 1, Drosophila melanogaster, MIgG1, kappa light chain, Drosophila/Planococcus citri, Su(var)205, HP1, CG8409, AB_528276, Monoclonal, Drosophila antigens/Nucleus, Immunofluorescence/Western Blot/Immunoprecipitation/Chromatin Immunoprecipitation
抗原分子量 :
Predicted: 23 kDa; Apparent 24 kDa
基因 :
Su(var)205
Alternate Gene Name(s) :
HP1, CG8409
UniProt数据库编号 :
P05205
抗体登记处号码 :
AB_528276
免疫原 :
Nuclear proteins extracted in 2.0 M potassium thiocyanate
免疫原序列 :
总数蛋白
克隆性 :
单克隆
Myeloma Strain :
Sp2/0 Ag14
表位定位 :
No
Recommended Applications :
染色质免疫沉淀 , 免疫荧光, 免疫沉淀, 免疫印迹
Immunoblotting (legacy) :
Yes
免疫组化PubMed IDs :
27687497
免疫荧光PubMed IDs :
3099166 9311988 9844626 12723693 16258543 7664737 16892059 12756231 15304225 15704177 17327272 18344984 24820420 19584931 20961390 22291607 18039863 30389853
免疫印迹PubMed IDs :
3099166 27687497 9311988 12510197 16258543 16892059 12756231 15304225 18344984 15905474 24820420 22291607
免疫沉淀PubMed IDs :
19798443 19584931
染色质免疫沉淀 PubMed IDs :
12756231 18344984 20961390 22291607
DSHB增长培养基 :
RPMI
References (legacy) :
Mol. Cell. Biol. 6, 3862-3872.; Proc. Natl. Acad. Sci. USA 87, 9923-9927.
公司信息
Developmental Studies Hybridoma Bank
University of Iowa
dshb@uiowa.edu
http://dshb.biology.uiowa.edu
公司总部: 美国
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构,为生命科学研究领域及诊断领域,提供高质量的抗体等产品。