产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
雌激素受体β(ER 2)
目录 :
CWK-F12
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
CWK-F12
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 免疫印迹基因敲除验证
文章摘录数: 19
出版应用/物种/样本/稀释参考文献
  • 免疫印迹基因敲除验证; 小鼠; 图 1c
  • 免疫沉淀; 小鼠; 图 3b
Yuan B, Yang J, Dubeau L, Hu Y, Li R. A Phosphotyrosine Switch in Estrogen Receptor β Is Required for Mouse Ovarian Function. Front Cell Dev Biol. 2021;9:649087 pubmed 出版商
Nelson A, Groen A, Miller J, Warren A, Holmes K, Tarulli G, et al. Comprehensive assessment of estrogen receptor beta antibodies in cancer cell line models and tissue reveals critical limitations in reagent specificity. Mol Cell Endocrinol. 2017;440:138-150 pubmed 出版商
Monsivais D, Dyson M, Yin P, Navarro A, Coon J, Pavone M, et al. Estrogen receptor β regulates endometriotic cell survival through serum and glucocorticoid-regulated kinase activation. Fertil Steril. 2016;105:1266-1273 pubmed 出版商
Monsivais D, Dyson M, Yin P, Coon J, Navarro A, Feng G, et al. ER?- and prostaglandin E2-regulated pathways integrate cell proliferation via Ras-like and estrogen-regulated growth inhibitor in endometriosis. Mol Endocrinol. 2014;28:1304-15 pubmed 出版商
Jiang Y, Gong P, Madak Erdogan Z, Martin T, Jeyakumar M, Carlson K, et al. Mechanisms enforcing the estrogen receptor ? selectivity of botanical estrogens. FASEB J. 2013;27:4406-18 pubmed 出版商
Chang E, Frasor J, Komm B, Katzenellenbogen B. Impact of estrogen receptor beta on gene networks regulated by estrogen receptor alpha in breast cancer cells. Endocrinology. 2006;147:4831-42 pubmed
Duong V, Licznar A, Margueron R, Boulle N, Busson M, Lacroix M, et al. ERalpha and ERbeta expression and transcriptional activity are differentially regulated by HDAC inhibitors. Oncogene. 2006;25:1799-806 pubmed
Aghmesheh M, Edwards L, Clarke C, Byth K, Katzenellenbogen B, Russell P, et al. Expression of steroid hormone receptors in BRCA1-associated ovarian carcinomas. Gynecol Oncol. 2005;97:16-25 pubmed
Chen J, Delannoy M, Cooke C, Yager J. Mitochondrial localization of ERalpha and ERbeta in human MCF7 cells. Am J Physiol Endocrinol Metab. 2004;286:E1011-22 pubmed
Tonetti D, Rubenstein R, DeLeon M, Zhao H, Pappas S, Bentrem D, et al. Stable transfection of an estrogen receptor beta cDNA isoform into MDA-MB-231 breast cancer cells. J Steroid Biochem Mol Biol. 2003;87:47-55 pubmed
Watanabe T, Akishita M, He H, Miyahara Y, Nagano K, Nakaoka T, et al. 17 beta-estradiol inhibits cardiac fibroblast growth through both subtypes of estrogen receptor. Biochem Biophys Res Commun. 2003;311:454-9 pubmed
Watanabe T, Akishita M, Nakaoka T, Kozaki K, Miyahara Y, He H, et al. Estrogen receptor beta mediates the inhibitory effect of estradiol on vascular smooth muscle cell proliferation. Cardiovasc Res. 2003;59:734-44 pubmed
Bukovsky A, Caudle M, Cekanova M, Fernando R, Wimalasena J, Foster J, et al. Placental expression of estrogen receptor beta and its hormone binding variant--comparison with estrogen receptor alpha and a role for estrogen receptors in asymmetric division and differentiation of estrogen-dependent cells. Reprod Biol Endocrinol. 2003;1:36 pubmed
Kulakosky P, Klinge C. Maximizing production of estrogen receptor beta with the baculovirus expression system. Biotechniques. 2003;34:334-8, 340-3 pubmed
Kowalski A, Graddy L, Vale Cruz D, Choi I, Katzenellenbogen B, Simmen F, et al. Molecular cloning of porcine estrogen receptor-beta complementary DNAs and developmental expression in periimplantation embryos. Biol Reprod. 2002;66:760-9 pubmed
Loven M, Likhite V, Choi I, Nardulli A. Estrogen response elements alter coactivator recruitment through allosteric modulation of estrogen receptor beta conformation. J Biol Chem. 2001;276:45282-8 pubmed
Lazennec G, Bresson D, Lucas A, Chauveau C, Vignon F. ER beta inhibits proliferation and invasion of breast cancer cells. Endocrinology. 2001;142:4120-30 pubmed
Loven M, Wood J, Nardulli A. Interaction of estrogen receptors alpha and beta with estrogen response elements. Mol Cell Endocrinol. 2001;181:151-63 pubmed
Choi I, Ko C, Park Sarge O, Nie R, Hess R, Graves C, et al. Human estrogen receptor beta-specific monoclonal antibodies: characterization and use in studies of estrogen receptor beta protein expression in reproductive tissues. Mol Cell Endocrinol. 2001;181:139-50 pubmed
产品信息
内部号码 :
27204
名称 :
CWK-F12
Depositor Name :
Katzenellenbogen, B.S.
Depositor Institution :
University of Illinois
Date Deposited :
3/30/17
Allow Hybridoma Distribution :
No
Cells Available (legacy) :
No
抗原 :
雌激素受体β(ER 2)
抗原物种 :
人类
宿主物种 :
小鼠
抗体亚型 :
MIgG2b
Positive Tested Species Reactivity :
人类, 小鼠, 猪, 大鼠
Initial Publication Pubmed ID :
11476948 (Choi et al 2001)
Depositor Notes (Special Instructions) :
This monoclonal antibody has recently be shown to be specific for ER beta unlike other commonly used anti-ER beta antibodies (see Nelson et al 2017 PMID 27889472).
Collections :
Human,Nucleus,Transcription factors
搜索关键词 :
Katzenellenbogen, B.S., Estrogen receptor beta (ER 2), Human, MIgG2b, Human/Rat/Mouse/Porcine, ESR2, Erb, NR3A2, , Monoclonal, Human/Nucleus/Transcription factors, Western blot/ELISA/Immunoprecipitation/Immunohistochemistry/FFPE/Function blocking/Chromatin immunoprecipitation/Immunofluorescence, AB_2722105
抗原分子量 :
59 kDa
基因 :
ESR2
Alternate Gene Name(s) :
Erb, NR3A2
UniProt数据库编号 :
Q92731
抗体登记处号码 :
AB_2722105
免疫原 :
E2配体结合区域
免疫原序列 :
a.a。 256-505
克隆性 :
单克隆
Myeloma Strain :
SP 2/0
表位定位 :
No
表位定位Pubmed登录号 :
11476948
Recommended Applications :
Chromatin Immunoprecipitation,ELISA,FFPE,Function Blocking,Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot
免疫组化PubMed IDs :
11476948 27889472 11517191 11870084 12740031 15790432
免疫荧光PubMed IDs :
14736707
免疫印迹PubMed IDs :
11476948 27889472 11517191 11476949 11870084 14736707 23882126 14630090 16158045 12613256 16809442 12740031 14592435 14499875 24992181
免疫沉淀PubMed IDs :
11476948
染色质免疫沉淀 PubMed IDs :
23882126 26827666 24992181
酶联免疫吸附测定PubMed IDs :
11476948
FFPE PubMed IDs :
11476948 27889472 11870084 15790432
Function Blocking Pubmed IDs :
11517191 11574541
其他信息 :
RRID: AB_2722105
DSHB增长培养基 :
Iscove's
公司信息
Developmental Studies Hybridoma Bank
University of Iowa
dshb@uiowa.edu
http://dshb.biology.uiowa.edu
公司总部: 美国
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构,为生命科学研究领域及诊断领域,提供高质量的抗体等产品。