产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
cysteine string protein (CSP), Drosophila common
目录 :
DCSP-2(6D6)
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
DCSP-2(6D6)
反应物种 :
果蝇
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
文章摘录数: 20
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 果蝇
Babic M, Russo G, Wellington A, Sangston R, Gonzalez M, Zinsmaier K. Miro's N-terminal GTPase domain is required for transport of mitochondria into axons and dendrites. J Neurosci. 2015;35:5754-71 pubmed 出版商
Huang Y, Huang S, Lam S, Liu Z, Shui G, Zhang Y. Acsl, the Drosophila ortholog of intellectual-disability-related ACSL4, inhibits synaptic growth by altered lipids. J Cell Sci. 2016;129:4034-4045 pubmed
Winding M, Kelliher M, Lu W, Wildonger J, Gelfand V. Role of kinesin-1-based microtubule sliding in Drosophila nervous system development. Proc Natl Acad Sci U S A. 2016;113:E4985-94 pubmed 出版商
Li W, Yao A, Zhi H, Kaur K, Zhu Y, Jia M, et al. Angelman Syndrome Protein Ube3a Regulates Synaptic Growth and Endocytosis by Inhibiting BMP Signaling in Drosophila. PLoS Genet. 2016;12:e1006062 pubmed 出版商
Liu Z, Huang Y, Hu W, Huang S, Wang Q, Han J, et al. dAcsl, the Drosophila ortholog of acyl-CoA synthetase long-chain family member 3 and 4, inhibits synapse growth by attenuating bone morphogenetic protein signaling via endocytic recycling. J Neurosci. 2014;34:2785-96 pubmed 出版商
Dason J, Smith A, Marin L, Charlton M. Cholesterol and F-actin are required for clustering of recycling synaptic vesicle proteins in the presynaptic plasma membrane. J Physiol. 2014;592:621-33 pubmed 出版商
Duncan J, Lytle N, Zuniga A, Goldstein L. The Microtubule Regulatory Protein Stathmin Is Required to Maintain the Integrity of Axonal Microtubules in Drosophila. PLoS ONE. 2013;8:e68324 pubmed 出版商
Beck E, Gasque G, Imlach W, Jiao W, Jiwon Choi B, Wu P, et al. Regulation of Fasciclin II and synaptic terminal development by the splicing factor beag. J Neurosci. 2012;32:7058-73 pubmed 出版商
O Sullivan N, Jahn T, Reid E, O Kane C. Reticulon-like-1, the Drosophila orthologue of the hereditary spastic paraplegia gene reticulon 2, is required for organization of endoplasmic reticulum and of distal motor axons. Hum Mol Genet. 2012;21:3356-65 pubmed 出版商
Bhogal B, Jepson J, Savva Y, Pepper A, Reenan R, Jongens T. Modulation of dADAR-dependent RNA editing by the Drosophila fragile X mental retardation protein. Nat Neurosci. 2011;14:1517-24 pubmed 出版商
Wang J, Brent J, Tomlinson A, Shneider N, McCabe B. The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span. J Clin Invest. 2011;121:4118-26 pubmed 出版商
Wang S, Yang J, Tsai A, Kuca T, Sanny J, Lee J, et al. Drosophila adducin regulates Dlg phosphorylation and targeting of Dlg to the synapse and epithelial membrane. Dev Biol. 2011;357:392-403 pubmed 出版商
Yao A, Jin S, Li X, Liu Z, Ma X, Tang J, et al. Drosophila FMRP regulates microtubule network formation and axonal transport of mitochondria. Hum Mol Genet. 2011;20:51-63 pubmed 出版商
LORENZO D, Li M, Mische S, Armbrust K, Ranum L, Hays T. Spectrin mutations that cause spinocerebellar ataxia type 5 impair axonal transport and induce neurodegeneration in Drosophila. J Cell Biol. 2010;189:143-58 pubmed 出版商
Stowers R, Isacoff E. Drosophila huntingtin-interacting protein 14 is a presynaptic protein required for photoreceptor synaptic transmission and expression of the palmitoylated proteins synaptosome-associated protein 25 and cysteine string protein. J Neurosci. 2007;27:12874-83 pubmed
Zeng X, Sun M, Liu L, Chen F, Wei L, Xie W. Neurexin-1 is required for synapse formation and larvae associative learning in Drosophila. FEBS Lett. 2007;581:2509-16 pubmed
Serpe M, O Connor M. The metalloprotease tolloid-related and its TGF-beta-like substrate Dawdle regulate Drosophila motoneuron axon guidance. Development. 2006;133:4969-79 pubmed
Arnold C, Reisch N, Leibold C, Becker S, Prüfert K, Sautter K, et al. Structure-function analysis of the cysteine string protein in Drosophila: cysteine string, linker and C terminus. J Exp Biol. 2004;207:1323-34 pubmed
Eberle K, Zinsmaier K, Buchner S, Gruhn M, Jenni M, Arnold C, et al. Wide distribution of the cysteine string proteins in Drosophila tissues revealed by targeted mutagenesis. Cell Tissue Res. 1998;294:203-17 pubmed
Zinsmaier K, Eberle K, Buchner E, Walter N, Benzer S. Paralysis and early death in cysteine string protein mutants of Drosophila. Science. 1994;263:977-80 pubmed
产品信息
内部号码 :
903
名称 :
DCSP-2(6D6)
Depositor Name :
Benzer, S.
Depositor Institution :
California Institute of Technology
Date Deposited :
4/27/05
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
抗原 :
cysteine string protein (CSP), Drosophila common
抗原物种 :
果蝇
宿主物种 :
小鼠
抗体亚型 :
MIgG2b
Isotype for catalog (legacy) :
IgG2b
Positive Tested Species Reactivity :
果蝇
Species Tested (legacy) :
果蝇
Initial Publication Pubmed ID :
8310297
Collections :
Cell markers,Drosophila antigens,Neurodevelopment
搜索关键词 :
Benzer, S., cysteine string protein (CSP), Drosophila common, Drosophila, MIgG2b, Drosophila, Csp, CG6395, AB_528183, monoclonal, Drosophila antigens/Neurodevelopment/Cell markers, Immunohistochemistry/Immunofluorescence/Western Blot/Immunoprecipitation
抗原分子量 :
Predicted: multiple isoforms at 24 and 27 kDa. Observed with mAb DCSP-2: 32, 33, 34, and 36 kDa.
基因 :
Csp
Alternate Gene Name(s) :
CG6395
UniProt数据库编号 :
Q03751
抗体登记处号码 :
AB_528183
免疫原 :
重组CSP/谷胱甘肽S-转移酶融合蛋白
免疫原序列 :
全长蛋白
克隆性 :
单克隆
表位定位 :
Yes
Epitope Location or Sequence :
REQAGGQP, aa 218-222 of isoform 1 (Uniprot ID: Q03751-1).
表位定位Pubmed登录号 :
15010483
Recommended Applications :
免疫荧光, 免疫组化, 免疫沉淀, 免疫印迹
Immunoblotting (legacy) :
Yes
免疫组化PubMed IDs :
8310297 9799436 21791202
免疫荧光PubMed IDs :
24297851 17119021 18032660 24553921 22037499 20368622 22543973 21881207 20935173 27512046 27232889 27656110 22593074 23840848 25855186 30610177
免疫印迹PubMed IDs :
8310297 9799436 15010483 17498701 24553921
其他信息 :
This antibody recognizes all known CSP isoforms and labels all synapses. See [PMID: 9799436 and 8310297] for a comparison between DCSP-1, DCSP-2 and DCSP3 mAbs. DCSP-2 is often used as a synaptic vesicle marker. CSP is also known as DnaJ homolog subfamily C member 5 homolog.
DSHB增长培养基 :
HL-1
References (legacy) :
Science 263, 977-980.; J. Neurosci. 32(20), 7058-7073.; PLoS ONE 8(6), e68324. Doi:10.1371/journal.pone.0068324.
公司信息
Developmental Studies Hybridoma Bank
University of Iowa
dshb@uiowa.edu
http://dshb.biology.uiowa.edu
公司总部: 美国
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构,为生命科学研究领域及诊断领域,提供高质量的抗体等产品。