产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
LAMP-1(人类)
目录 :
H4A3
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
H4A3
反应物种 :
fission yeast, 人类, 小鼠, 大鼠,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 其他
文章摘录数: 162
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 图 1c
Prabhu A, Kang I, De Pace R, Wassif C, Fujiwara H, Kell P, et al. A human iPSC-derived inducible neuronal model of Niemann-Pick disease, type C1. BMC Biol. 2021;19:218 pubmed 出版商
  • 免疫细胞化学; 人类; 1:400; 图 s3a
Mathieu M, Nevo N, Jouve M, Valenzuela J, Maurin M, Verweij F, et al. Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9. Nat Commun. 2021;12:4389 pubmed 出版商
  • 免疫细胞化学; 人类; 图 5c
Takahashi K, Kanerva K, Vanharanta L, Almeida Souza L, Lietha D, Olkkonen V, et al. ORP2 couples LDL-cholesterol transport to FAK activation by endosomal cholesterol/PI(4,5)P2 exchange. EMBO J. 2021;40:e106871 pubmed 出版商
  • 其他; 人类; 1:10; 图 s1h
Hess M, Krainer I, Filipek P, Witting B, Gutleben K, Vietor I, et al. Advanced Microscopy for Liver and Gut Ultrastructural Pathology in Patients with MVID and PFIC Caused by MYO5B Mutations. J Clin Med. 2021;10: pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 s5b
Caballero B, Bourdenx M, Luengo E, Díaz A, Sohn P, Chen X, et al. Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice. Nat Commun. 2021;12:2238 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 4g
Ben Sasson A, Watson J, Sheffler W, Johnson M, Bittleston A, Somasundaram L, et al. Design of biologically active binary protein 2D materials. Nature. 2021;589:468-473 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2c
Liao Y, Fernandopulle M, Wang G, Choi H, Hao L, Drerup C, et al. RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether. Cell. 2019;179:147-164.e20 pubmed 出版商
  • 免疫印迹; 人类; 图 1h
Xiao J, Luo J, Hu A, Xiao T, Li M, Kong Z, et al. Cholesterol transport through the peroxisome-ER membrane contacts tethered by PI(4,5)P2 and extended synaptotagmins. Sci China Life Sci. 2019;: pubmed 出版商
  • 免疫细胞化学; 人类; 图 s1f
Quinney K, Frankel E, Shankar R, Kasberg W, Luong P, Audhya A. Growth factor stimulation promotes multivesicular endosome biogenesis by prolonging recruitment of the late-acting ESCRT machinery. Proc Natl Acad Sci U S A. 2019;116:6858-6867 pubmed 出版商
  • 免疫细胞化学; 人类; 2 ug/ml; 图 s1d
Bae D, Moore K, Mella J, Hayashi S, Hollien J. Degradation of Blos1 mRNA by IRE1 repositions lysosomes and protects cells from stress. J Cell Biol. 2019;218:1118-1127 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000; 图 1e
Skowyra M, Schlesinger P, Naismith T, Hanson P. Triggered recruitment of ESCRT machinery promotes endolysosomal repair. Science. 2018;360: pubmed 出版商
  • 免疫细胞化学; 人类; 图 s1e
Takada N, Naito T, Inoue T, Nakayama K, Takatsu H, Shin H. Phospholipid-flipping activity of P4-ATPase drives membrane curvature. EMBO J. 2018;37: pubmed 出版商
  • 免疫印迹; 人类; 图 5d
Marrone L, Bus C, Schöndorf D, Fitzgerald J, Kübler M, Schmid B, et al. Generation of iPSCs carrying a common LRRK2 risk allele for in vitro modeling of idiopathic Parkinson's disease. PLoS ONE. 2018;13:e0192497 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:250; 图 9d
Krey J, Dumont R, Wilmarth P, David L, Johnson K, Barr Gillespie P. ELMOD1 Stimulates ARF6-GTP Hydrolysis to Stabilize Apical Structures in Developing Vestibular Hair Cells. J Neurosci. 2018;38:843-857 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 s4d
Jimenez Orgaz A, Kvainickas A, Nägele H, Denner J, Eimer S, Dengjel J, et al. Control of RAB7 activity and localization through the retromer-TBC1D5 complex enables RAB7-dependent mitophagy. EMBO J. 2018;37:235-254 pubmed 出版商
  • 免疫细胞化学; 人类; 1:5; 图 7c
Shiba Fukushima K, Ishikawa K, Inoshita T, Izawa N, Takanashi M, Sato S, et al. Evidence that phosphorylated ubiquitin signaling is involved in the etiology of Parkinson's disease. Hum Mol Genet. 2017;26:3172-3185 pubmed 出版商
  • 免疫细胞化学; 人类; 图 7a
Wilhelm L, Wendling C, Vedie B, Kobayashi T, Chenard M, Tomasetto C, et al. STARD3 mediates endoplasmic reticulum-to-endosome cholesterol transport at membrane contact sites. EMBO J. 2017;36:1412-1433 pubmed 出版商
  • 免疫印迹; 人类; 图 10c
Jung J, Nayak A, Schaeffer V, Starzetz T, Kirsch A, Muller S, et al. Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator. elife. 2017;6: pubmed 出版商
  • 免疫印迹; 人类; 1:400; 图 5b
Borgia D, Malena A, Spinazzi M, Desbats M, Salviati L, Russell A, et al. Increased mitophagy in the skeletal muscle of spinal and bulbar muscular atrophy patients. Hum Mol Genet. 2017;26:1087-1103 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1c
Cianciola N, Chung S, Manor D, Carlin C. Adenovirus Modulates Toll-Like Receptor 4 Signaling by Reprogramming ORP1L-VAP Protein Contacts for Cholesterol Transport from Endosomes to the Endoplasmic Reticulum. J Virol. 2017;91: pubmed 出版商
  • 免疫印迹; 人类; 图 6e
Shi B, Huang Q, Birkett R, Doyle R, Dorfleutner A, Stehlik C, et al. SNAPIN is critical for lysosomal acidification and autophagosome maturation in macrophages. Autophagy. 2017;13:285-301 pubmed 出版商
  • 流式细胞仪; 人类; 图 s6d
Galindo Albarrán A, López Portales O, Gutiérrez Reyna D, Rodríguez Jorge O, Sánchez Villanueva J, Ramirez Pliego O, et al. CD8+ T Cells from Human Neonates Are Biased toward an Innate Immune Response. Cell Rep. 2016;17:2151-2160 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:300; 图 3
Jaber N, Mohd Naim N, Wang Z, Deleon J, Kim S, Zhong H, et al. Vps34 regulates Rab7 and late endocytic trafficking through recruitment of the GTPase-activating protein Armus. J Cell Sci. 2016;129:4424-4435 pubmed
  • 免疫细胞化学; 人类; 图 2a
Rofe A, Davis L, Whittingham J, Latimer Bowman E, Wilkinson A, Pryor P. The Rhodococcus equi virulence protein VapA disrupts endolysosome function and stimulates lysosome biogenesis. Microbiologyopen. 2017;6: pubmed 出版商
  • 免疫细胞化学; 人类; 图 6a
Roberts B, Svoboda R, Overmiller A, Lewis J, Kowalczyk A, Mahoney M, et al. Palmitoylation of Desmoglein 2 Is a Regulator of Assembly Dynamics and Protein Turnover. J Biol Chem. 2016;291:24857-24865 pubmed
  • 免疫细胞化学; 小鼠; 1:200; 图 2b
Rahman N, Ramos Espiritu L, Milner T, Buck J, Levin L. Soluble adenylyl cyclase is essential for proper lysosomal acidification. J Gen Physiol. 2016;148:325-39 pubmed 出版商
  • 免疫细胞化学; 犬; 图 4a
Dolat L, Spiliotis E. Septins promote macropinosome maturation and traffic to the lysosome by facilitating membrane fusion. J Cell Biol. 2016;214:517-27 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2d
McMillan K, Gallon M, Jellett A, Clairfeuille T, Tilley F, McGough I, et al. Atypical parkinsonism-associated retromer mutant alters endosomal sorting of specific cargo proteins. J Cell Biol. 2016;214:389-99 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6a
Zhang X, Cheng X, Yu L, Yang J, Calvo R, Patnaik S, et al. MCOLN1 is a ROS sensor in lysosomes that regulates autophagy. Nat Commun. 2016;7:12109 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2a
  • 免疫印迹; 人类; 图 2b
Wu X, Zhao L, Chen Z, Ji X, Qiao X, Jin Y, et al. FLCN Maintains the Leucine Level in Lysosome to Stimulate mTORC1. PLoS ONE. 2016;11:e0157100 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1a
Starling G, Yip Y, Sanger A, Morton P, Eden E, Dodding M. Folliculin directs the formation of a Rab34-RILP complex to control the nutrient-dependent dynamic distribution of lysosomes. EMBO Rep. 2016;17:823-41 pubmed 出版商
  • 免疫细胞化学; 人类; 图 7g
Li Z, Ji X, Wang W, Liu J, Liang X, Wu H, et al. Ammonia Induces Autophagy through Dopamine Receptor D3 and MTOR. PLoS ONE. 2016;11:e0153526 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:1000; 表 1
Ito M, Nakamura K, Mori F, Miki Y, Tanji K, Wakabayashi K. Novel eosinophilic neuronal cytoplasmic inclusions in the external cuneate nucleus of humans. Neuropathology. 2016;36:441-447 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s2
Hatori Y, Yan Y, Schmidt K, Furukawa E, Hasan N, Yang N, et al. Neuronal differentiation is associated with a redox-regulated increase of copper flow to the secretory pathway. Nat Commun. 2016;7:10640 pubmed 出版商
  • 免疫印迹; 人类; 图 6a
Pérez L, McLetchie S, Gardiner G, Deffit S, Zhou D, Blum J. LAMP-2C Inhibits MHC Class II Presentation of Cytoplasmic Antigens by Disrupting Chaperone-Mediated Autophagy. J Immunol. 2016;196:2457-65 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 2
Circu M, Dykes S, Carroll J, Kelly K, Galiano F, Greer A, et al. A Novel High Content Imaging-Based Screen Identifies the Anti-Helminthic Niclosamide as an Inhibitor of Lysosome Anterograde Trafficking and Prostate Cancer Cell Invasion. PLoS ONE. 2016;11:e0146931 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1a
Zhang S, Schneider L, Vick B, Grunert M, Jeremias I, Menche D, et al. Anti-leukemic effects of the V-ATPase inhibitor Archazolid A. Oncotarget. 2015;6:43508-28 pubmed 出版商
  • 免疫组化; 人类; 1:100
Scifo E, Szwajda A, Soliymani R, Pezzini F, Bianchi M, Dapkunas A, et al. Quantitative analysis of PPT1 interactome in human neuroblastoma cells. Data Brief. 2015;4:207-16 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s4a
Hobbs R, DePianto D, Jacob J, Han M, Chung B, Batazzi A, et al. Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes. Nat Genet. 2015;47:933-8 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 6
Costantini L, Baloban M, Markwardt M, Rizzo M, Guo F, Verkhusha V, et al. A palette of fluorescent proteins optimized for diverse cellular environments. Nat Commun. 2015;6:7670 pubmed 出版商
  • 免疫细胞化学; 人类; 1:250; 图 4
Cao Q, Zhong X, Zou Y, Murrell Lagnado R, Zhu M, Dong X. Calcium release through P2X4 activates calmodulin to promote endolysosomal membrane fusion. J Cell Biol. 2015;209:879-94 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 s6
  • 免疫印迹; 人类; 1:500; 图 s7
Akizu N, Cantagrel V, Zaki M, Al Gazali L, Wang X, Rosti R, et al. Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction. Nat Genet. 2015;47:528-34 pubmed 出版商
  • 免疫细胞化学; 人类; 图 5
  • 免疫印迹; 人类; 图 5
Brandstaetter H, Kishi Itakura C, Tumbarello D, Manstein D, Buss F. Loss of functional MYO1C/myosin 1c, a motor protein involved in lipid raft trafficking, disrupts autophagosome-lysosome fusion. Autophagy. 2014;10:2310-23 pubmed 出版商
  • 免疫细胞化学; 人类; 图 4, 5
Ram S, Kim D, Ober R, Ward E. The level of HER2 expression is a predictor of antibody-HER2 trafficking behavior in cancer cells. MAbs. 2014;6:1211-9 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s9f
Boucrot E, Ferreira A, Almeida Souza L, Debard S, Vallis Y, Howard G, et al. Endophilin marks and controls a clathrin-independent endocytic pathway. Nature. 2015;517:460-5 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 5
Bohnsack R, Warejcka D, Wang L, Gillespie S, Bernstein A, Twining S, et al. Expression of insulin-like growth factor 2 receptor in corneal keratocytes during differentiation and in response to wound healing. Invest Ophthalmol Vis Sci. 2014;55:7697-708 pubmed 出版商
  • 免疫细胞化学; 人类
Ye S, Huang Y, Joshi S, Zhang J, Yang F, Zhang G, et al. Platelet secretion and hemostasis require syntaxin-binding protein STXBP5. J Clin Invest. 2014;124:4517-28 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2, 3, 4
Menhofer M, Bartel D, Liebl J, Kubisch R, Busse J, Wagner E, et al. In vitro and in vivo characterization of the actin polymerizing compound chondramide as an angiogenic inhibitor. Cardiovasc Res. 2014;104:303-14 pubmed 出版商
  • 流式细胞仪; 人类; 图 2
Madhavi V, Ana Sosa Batiz F, Jegaskanda S, Center R, Winnall W, Parsons M, et al. Antibody-dependent effector functions against HIV decline in subjects receiving antiretroviral therapy. J Infect Dis. 2015;211:529-38 pubmed 出版商
  • 免疫细胞化学; fission yeast; 图 s4
Cheng J, Fujita A, Yamamoto H, Tatematsu T, Kakuta S, Obara K, et al. Yeast and mammalian autophagosomes exhibit distinct phosphatidylinositol 3-phosphate asymmetries. Nat Commun. 2014;5:3207 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:1000
Kon T, Mori F, Tanji K, Miki Y, Kimura T, Wakabayashi K. Giant cell polymyositis and myocarditis associated with myasthenia gravis and thymoma. Neuropathology. 2013;33:281-7 pubmed 出版商
  • 免疫细胞化学; 人类
Wild P, Farhan H, McEwan D, Wagner S, Rogov V, Brady N, et al. Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth. Science. 2011;333:228-33 pubmed 出版商
  • 免疫细胞化学; 人类
Yu X, McGourty K, Liu M, Unsworth K, Holden D. pH sensing by intracellular Salmonella induces effector translocation. Science. 2010;328:1040-3 pubmed 出版商
  • 免疫印迹; 人类
Howe D, Heinzen R. Fractionation of the Coxiella burnetii parasitophorous vacuole. Methods Mol Biol. 2008;445:389-406 pubmed 出版商
Chong A, Starr T, Finn C, Steele Mortimer O. A role for the Salmonella Type III Secretion System 1 in bacterial adaptation to the cytosol of epithelial cells. Mol Microbiol. 2019;112:1270-1283 pubmed 出版商
Piccolo P, Sabatino V, Mithbaokar P, Polishchuk E, Hicks J, Polishchuk R, et al. Skin fibroblasts of patients with geleophysic dysplasia due to FBN1 mutations have lysosomal inclusions and losartan improves their microfibril deposition defect. Mol Genet Genomic Med. 2019;7:e844 pubmed 出版商
Byndloss M, Tsai A, Walker G, Miller C, Young B, English B, et al. Brucella abortus Infection of Placental Trophoblasts Triggers Endoplasmic Reticulum Stress-Mediated Cell Death and Fetal Loss via Type IV Secretion System-Dependent Activation of CHOP. MBio. 2019;10: pubmed 出版商
Stathakos P, Jiménez Moreno N, Crompton L, Nistor P, Caldwell M, Lane J. Imaging Autophagy in hiPSC-Derived Midbrain Dopaminergic Neuronal Cultures for Parkinson's Disease Research. Methods Mol Biol. 2019;1880:257-280 pubmed 出版商
Murakami K, Etlinger J. Role of SMURF1 ubiquitin ligase in BMP receptor trafficking and signaling. Cell Signal. 2019;54:139-149 pubmed 出版商
Augustin H, McGourty K, Allen M, Madem S, Adcott J, Kerr F, et al. Reduced insulin signaling maintains electrical transmission in a neural circuit in aging flies. PLoS Biol. 2017;15:e2001655 pubmed 出版商
Bekier M, Wang L, Li J, Huang H, Tang D, Zhang X, et al. Knockout of the Golgi stacking proteins GRASP55 and GRASP65 impairs Golgi structure and function. Mol Biol Cell. 2017;28:2833-2842 pubmed 出版商
Totland M, Bergsland C, Fykerud T, Knudsen L, Rasmussen N, Eide P, et al. The E3 ubiquitin ligase NEDD4 induces endocytosis and lysosomal sorting of connexin 43 to promote loss of gap junctions. J Cell Sci. 2017;130:2867-2882 pubmed 出版商
Tournu H, Carroll J, Latimer B, Dragoi A, Dykes S, Cardelli J, et al. Identification of small molecules that disrupt vacuolar function in the pathogen Candida albicans. PLoS ONE. 2017;12:e0171145 pubmed 出版商
Zhou M, Wiener H, Su W, Zhou Y, Liot C, Ahearn I, et al. VPS35 binds farnesylated N-Ras in the cytosol to regulate N-Ras trafficking. J Cell Biol. 2016;214:445-58 pubmed 出版商
Kohler L, Reed S, Sarraf S, Arteaga D, Newton H, Roy C. Effector Protein Cig2 Decreases Host Tolerance of Infection by Directing Constitutive Fusion of Autophagosomes with the Coxiella-Containing Vacuole. MBio. 2016;7: pubmed 出版商
Bento C, Ashkenazi A, Jimenez Sanchez M, Rubinsztein D. The Parkinson's disease-associated genes ATP13A2 and SYT11 regulate autophagy via a common pathway. Nat Commun. 2016;7:11803 pubmed 出版商
Marin Zapata P, Beese C, Jünger A, Dalmasso G, Brady N, Hamacher Brady A. Time course decomposition of cell heterogeneity in TFEB signaling states reveals homeostatic mechanisms restricting the magnitude and duration of TFEB responses to mTOR activity modulation. BMC Cancer. 2016;16:355 pubmed 出版商
Mell J, Viadas C, Moleres J, Sinha S, Fernández Calvet A, Porsch E, et al. Transformed Recombinant Enrichment Profiling Rapidly Identifies HMW1 as an Intracellular Invasion Locus in Haemophilus influenza. PLoS Pathog. 2016;12:e1005576 pubmed 出版商
O Brien M, Manches O, WILEN C, Gopal R, Huq R, Wu V, et al. CD4 Receptor is a Key Determinant of Divergent HIV-1 Sensing by Plasmacytoid Dendritic Cells. PLoS Pathog. 2016;12:e1005553 pubmed 出版商
Johnson D, Ostrowski P, Jaumouillé V, Grinstein S. The position of lysosomes within the cell determines their luminal pH. J Cell Biol. 2016;212:677-92 pubmed 出版商
Rodríguez Escudero M, Cid V, Molina M, Schulze Luehrmann J, Lührmann A, Rodríguez Escudero I. Studying Coxiella burnetii Type IV Substrates in the Yeast Saccharomyces cerevisiae: Focus on Subcellular Localization and Protein Aggregation. PLoS ONE. 2016;11:e0148032 pubmed 出版商
Kilpatrick B, Magalhães J, Beavan M, McNeill A, Gegg M, Cleeter M, et al. Endoplasmic reticulum and lysosomal Ca²⁺ stores are remodelled in GBA1-linked Parkinson disease patient fibroblasts. Cell Calcium. 2016;59:12-20 pubmed 出版商
Dou Z, Xu C, Donahue G, Shimi T, Pan J, Zhu J, et al. Autophagy mediates degradation of nuclear lamina. Nature. 2015;527:105-9 pubmed 出版商
Evans G, Caller L, Foster V, Crump C. Anion homeostasis is important for non-lytic release of BK polyomavirus from infected cells. Open Biol. 2015;5: pubmed 出版商
Prado M, Eickel N, De Niz M, Heitmann A, Agop Nersesian C, Wacker R, et al. Long-term live imaging reveals cytosolic immune responses of host hepatocytes against Plasmodium infection and parasite escape mechanisms. Autophagy. 2015;11:1561-79 pubmed 出版商
Wan M, Zhang W, Tian Y, Xu C, Xu T, Liu J, et al. Unraveling a molecular determinant for clathrin-independent internalization of the M2 muscarinic acetylcholine receptor. Sci Rep. 2015;5:11408 pubmed 出版商
Rasmussen J, Fletcher J, Long M, Allen L, Jones B. Characterization of Francisella tularensis Schu S4 mutants identified from a transposon library screened for O-antigen and capsule deficiencies. Front Microbiol. 2015;6:338 pubmed 出版商
Venè R, Tosetti F, Minghelli S, Poggi A, Ferrari N, Benelli R. Celecoxib increases EGF signaling in colon tumor associated fibroblasts, modulating EGFR expression and degradation. Oncotarget. 2015;6:12310-25 pubmed
Santiago Tirado F, Peng T, Yang M, Hang H, Doering T. A Single Protein S-acyl Transferase Acts through Diverse Substrates to Determine Cryptococcal Morphology, Stress Tolerance, and Pathogenic Outcome. PLoS Pathog. 2015;11:e1004908 pubmed 出版商
Dirk B, Jacob R, Johnson A, Pawlak E, Cavanagh P, Van Nynatten L, et al. Viral bimolecular fluorescence complementation: a novel tool to study intracellular vesicular trafficking pathways. PLoS ONE. 2015;10:e0125619 pubmed 出版商
Nakatsu F, Messa M, Nández R, Czapla H, Zou Y, Strittmatter S, et al. Sac2/INPP5F is an inositol 4-phosphatase that functions in the endocytic pathway. J Cell Biol. 2015;209:85-95 pubmed 出版商
Roboti P, Sato K, Lowe M. The golgin GMAP-210 is required for efficient membrane trafficking in the early secretory pathway. J Cell Sci. 2015;128:1595-606 pubmed 出版商
Cortes Canteli M, Mattei L, Richards A, Norris E, Strickland S. Fibrin deposited in the Alzheimer's disease brain promotes neuronal degeneration. Neurobiol Aging. 2015;36:608-17 pubmed 出版商
Hockey L, Kilpatrick B, Eden E, Lin Moshier Y, Brailoiu G, Brailoiu E, et al. Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition. J Cell Sci. 2015;128:232-8 pubmed 出版商
Canton J, Khezri R, Glogauer M, Grinstein S. Contrasting phagosome pH regulation and maturation in human M1 and M2 macrophages. Mol Biol Cell. 2014;25:3330-41 pubmed 出版商
Newton H, Kohler L, McDonough J, Temoche Diaz M, Crabill E, Hartland E, et al. A screen of Coxiella burnetii mutants reveals important roles for Dot/Icm effectors and host autophagy in vacuole biogenesis. PLoS Pathog. 2014;10:e1004286 pubmed 出版商
Mangieri L, Mader B, Thomas C, Taylor C, Luker A, Tse T, et al. ATP6V0C knockdown in neuroblastoma cells alters autophagy-lysosome pathway function and metabolism of proteins that accumulate in neurodegenerative disease. PLoS ONE. 2014;9:e93257 pubmed 出版商
Palibrk V, Lång E, Lang A, Schink K, Rowe A, Bøe S. Promyelocytic leukemia bodies tether to early endosomes during mitosis. Cell Cycle. 2014;13:1749-55 pubmed 出版商
Steffan J, Dykes S, Coleman D, Adams L, Rogers D, Carroll J, et al. Supporting a role for the GTPase Rab7 in prostate cancer progression. PLoS ONE. 2014;9:e87882 pubmed 出版商
Valapala M, Wilson C, Hose S, Bhutto I, Grebe R, Dong A, et al. Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/?A3/A1-crystallin via V-ATPase-MTORC1 signaling. Autophagy. 2014;10:480-96 pubmed 出版商
Hannemann S, Gao B, Galan J. Salmonella modulation of host cell gene expression promotes its intracellular growth. PLoS Pathog. 2013;9:e1003668 pubmed 出版商
Schowalter R, Buck C. The Merkel cell polyomavirus minor capsid protein. PLoS Pathog. 2013;9:e1003558 pubmed 出版商
Jensen S, Aaberg Jessen C, Christensen K, Kristensen B. Expression of the lysosomal-associated membrane protein-1 (LAMP-1) in astrocytomas. Int J Clin Exp Pathol. 2013;6:1294-305 pubmed
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产品信息
内部号码 :
503
名称 :
H4A3
Depositor Name :
August, J.T. / Hildreth, J.E.K.
Depositor Institution :
The Johns Hopkins University School of Medicine
Date Deposited :
4/12/93
Allow Hybridoma Distribution :
No
Cells Available (legacy) :
No
抗原 :
LAMP-1(人类)
抗原物种 :
人类
宿主物种 :
小鼠
抗体亚型 :
MIgG1
Isotype for catalog (legacy) :
IgG1
Positive Tested Species Reactivity :
仓鼠, 人类, 灵长类动物, 大鼠
Species Tested (legacy) :
human, hamster, monkey, rat
Initial Publication Pubmed ID :
2409098
Depositor Notes (Special Instructions) :
This antibody recognizes a membrane glycoprotein which interacts with selectins.
Collections :
CD antigens,Cell signaling,Human
搜索关键词 :
August, J.T. / Hildreth, J.E.K., Lysosomal-associated membrane protein 1; Lamp-1 ; CD107a, MIgG1, Hamster/Human/Primate/Rat, LAMP1, , AB_2296838, Monoclonal, LAMP1, LGP120, LAMPA, Immunofluorescence,Immunohistochemistry,Western Blot
抗原分子量 :
Predicted: 42 kDa; Apparent: 120 kDa
基因 :
溶酶体相关膜蛋白质1
Alternate Gene Name(s) :
CD107a, LGP120, LAMPA
UniProt数据库编号 :
P11279
抗体登记处号码 :
AB_2296838
Synonyms (Alternate Clone Names) :
CD107a
免疫原 :
Adherent spleen cells
克隆性 :
单克隆
Myeloma Strain :
P3X653-Ag8
表位定位 :
Yes
Epitope Location or Sequence :
苯巴比妥地区
表位定位Pubmed登录号 :
11511344
Recommended Applications :
免疫荧光, 免疫组化, 免疫印迹
Immunoblotting (legacy) :
yes
免疫组化PubMed IDs :
23826410 15944902 31350823
免疫荧光PubMed IDs :
25080348 23748470 23716606 23241026 23436907 23319555 23230297 23681233 23362322 22505584 27435465 30395943 30610703 31337727 31370104
免疫印迹PubMed IDs :
28814501 22070883 20173215 19910472 19286132 18817525 16565504 12021262 11342594 11441007
PubMed IDs :
25475538
其他信息 :
For experiments involving live cells and tissue, H4A3 supernatant is available without the antimicrobial ProClin. Contact us at 319-335-3826 or dshb@uiowa.edu for special ordering instructions.
DSHB增长培养基 :
Iscove's
References (legacy) :
J. Cell Biol. 101, 85-95.; Biochem. Soc. Symp. 51, 97-112.; J. Biol. Chem. 263, 8754-8758.; Arch. Biochem. Biophys. 268, 360-378.; J. Biol. Chem. 265, 5008-5013.; J. Biol. Chem. 265, 7419-7423.; J. Biol. Chem. 275(12), 8672-8679.; EMBO J. 23, 4560-4570.; Acta. Neuropathol. 108, 287-294.; Mol. Biol. Cell 15, 5420-5430.; Autophagy, 1(1), 23-36.; J. Cell. Sci. 119, 2003-2014.; Am. J. Pathol. 168 (4), 1309-1320.; Am. J. Hum. Genet. 81, 136-146.; BMC Cell Biology 10:84 doi:10.1186/1471-2121-10-84.; J. Biol. Chem. 286(33), 29166-29174.; J. Neurochem. 123, 298-309.; J. Cell Sci. 126(1), 60-66.; Neurobiol. Aging, In press. http://dx.doi.org/10.1016/j.neurobiolaging.2014.10.030.
公司信息
Developmental Studies Hybridoma Bank
University of Iowa
dshb@uiowa.edu
http://dshb.biology.uiowa.edu
公司总部: 美国
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构,为生命科学研究领域及诊断领域,提供高质量的抗体等产品。