产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
原肌球蛋白, hTPM3
目录 :
LC1
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
LC1
反应物种 :
人类
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀
文章摘录数: 15
| 参考文献 |
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Schevzov G, Whittaker S, Fath T, Lin J, Gunning P. Tropomyosin isoforms and reagents. Bioarchitecture. 2011;1:135-164 pubmed
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Martin C, Gunning P. Isoform sorting of tropomyosins. Adv Exp Med Biol. 2008;644:187-200 pubmed
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Eppinga R, Li Y, Lin J, Lin J. Tropomyosin and caldesmon regulate cytokinesis speed and membrane stability during cell division. Arch Biochem Biophys. 2006;456:161-74 pubmed
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Vera C, Lao J, Hamelberg D, Sung L. Mapping the tropomyosin isoform 5 binding site on human erythrocyte tropomodulin: further insights into E-Tmod/TM5 interaction. Arch Biochem Biophys. 2005;444:130-8 pubmed
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Schevzov G, Bryce N, Almonte Baldonado R, Joya J, Lin J, Hardeman E, et al. Specific features of neuronal size and shape are regulated by tropomyosin isoforms. Mol Biol Cell. 2005;16:3425-37 pubmed
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Lin J, Geng X, Bhattacharya S, Yu J, Reiter R, Sastri B, et al. Isolation and sequencing of a novel tropomyosin isoform preferentially associated with colon cancer. Gastroenterology. 2002;123:152-62 pubmed
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Vera C, Sood A, Gao K, Yee L, Lin J, Sung L. Tropomodulin-binding site mapped to residues 7-14 at the N-terminal heptad repeats of tropomyosin isoform 5. Arch Biochem Biophys. 2000;378:16-24 pubmed
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Sung L, Gao K, Yee L, Temm Grove C, Helfman D, Lin J, et al. Tropomyosin isoform 5b is expressed in human erythrocytes: implications of tropomodulin-TM5 or tropomodulin-TM5b complexes in the protofilament and hexagonal organization of membrane skeletons. Blood. 2000;95:1473-80 pubmed
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Kesari K, Yoshizaki N, Geng X, Lin J, Das K. Externalization of tropomyosin isoform 5 in colon epithelial cells. Clin Exp Immunol. 1999;118:219-27 pubmed
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Geng X, Biancone L, Dai H, Lin J, Yoshizaki N, Dasgupta A, et al. Tropomyosin isoforms in intestinal mucosa: production of autoantibodies to tropomyosin isoforms in ulcerative colitis. Gastroenterology. 1998;114:912-22 pubmed
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Lin J, Warren K, Wamboldt D, Wang T, Lin J. Tropomyosin isoforms in nonmuscle cells. Int Rev Cytol. 1997;170:1-38 pubmed
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Warren K, Lin J, McDermott J, Lin J. Forced expression of chimeric human fibroblast tropomyosin mutants affects cytokinesis. J Cell Biol. 1995;129:697-708 pubmed
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产品信息
内部号码 :
6137
名称 :
LC1
Depositor Name :
Lin, J.J.-C.
Depositor Institution :
University of Iowa
Date Deposited :
7/17/09
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
抗原 :
原肌球蛋白, hTPM3
抗原物种 :
人类
宿主物种 :
小鼠
抗体亚型 :
MIgG1
Isotype for catalog (legacy) :
IgG1
Positive Tested Species Reactivity :
仓鼠, 人类
Species Tested (legacy) :
human non-muscle, hamster (CHO) but not mouse
Initial Publication Pubmed ID :
7730405
Depositor Notes (Special Instructions) :
Recognizes Human non-muscle tropomyosin (hTM5), hamster (CHO) but not mouse.
Collections :
细胞骨架, 人类, 骨骼肌
搜索关键词 :
Lin, J.J.-C., tropomyosin, hTPM3, Human, MIgG1, human/hamster, TPM3, , AB_10572389, monoclonal, Cytoskeletal elements/skeletal muscle/Human, Immunofluorescence/Immunoprecipitation/Western Blot/Immunoprecipitation
抗原分子量 :
Apparent: 32 kDa
基因 :
TPM3
UniProt数据库编号 :
P06753
抗体登记处号码 :
AB_10572389
免疫原 :
Recombinant human tropomyosin isoform 5 and 4 fusion (hTM5/4) protein (N-terminal half of hTM5 and C-terminal half of hTM4).
免疫原序列 :
Partial protein
克隆性 :
单克隆
Myeloma Strain :
NS1
表位定位 :
Yes
Epitope Location or Sequence :
First ten aa of the human TPM3 exon 1b product
表位定位Pubmed登录号 :
22069507 10871039
Recommended Applications :
免疫荧光, 免疫沉淀, 免疫印迹
Immunoblotting (legacy) :
yes
免疫荧光PubMed IDs :
19209823 19690525 16854366
免疫印迹PubMed IDs :
22069507 9558279 10540182 10871039 7730405 10871039 12105844 10666227 23303457 21289288
免疫沉淀PubMed IDs :
16297372
PubMed IDs :
9002235
其他信息 :
Doesn't cross-react with rat or mouse tropomyosin.
DSHB增长培养基 :
Iscove's
References (legacy) :
J. Cell Biol. 129, 697-708.; Int. Rev. Cytol. 170, 1-38.; Gastroenterology 114, 912-922.; Clin. Exp. Immunol. 118, 219-227.; Blood 95, 1473-1480.; Arch. Biochem. Biophys. 378, 16-24.; Gastroenterology 123, 152-162.; Mol Biol. Cell 16, 3425-3437.; Arch. Biochem. Biophys. 456, 161-174.
公司信息
Developmental Studies Hybridoma Bank
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构，为生命科学研究领域及诊断领域，提供高质量的抗体等产品。