产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
LMP-1
目录 :
LMP1
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
LMP1
反应物种 :
秀丽隐杆线虫
应用 :
免疫印迹, 免疫细胞化学
文章摘录数: 5
参考文献
Huynh J, Dang H, Munoz Tucker I, O Ketch M, Liu I, Perno S, et al. ESCRT-Dependent Cell Death in a Caenorhabditis elegans Model of the Lysosomal Storage Disorder Mucolipidosis Type IV. Genetics. 2016;202:619-38 pubmed 出版商
Djeddi A, Al Rawi S, Deuve J, Perrois C, Liu Y, Russeau M, et al. Sperm-inherited organelle clearance in C. elegans relies on LC3-dependent autophagosome targeting to the pericentrosomal area. Development. 2015;142:1705-16 pubmed 出版商
Tanji T, Nishikori K, Shiraishi H, Maeda M, Ohashi Kobayashi A. Co-operative function and mutual stabilization of the half ATP-binding cassette transporters HAF-4 and HAF-9 in Caenorhabditis elegans. Biochem J. 2013;452:467-75 pubmed 出版商
Cheng L, Li B, Wang Z. Level-Set Minimization of Potential Controlled Hadwiger Valuations for Molecular Solvation. J Comput Phys. 2010;229:8497-8510 pubmed
Hadwiger G, Dour S, Arur S, Fox P, Nonet M. A monoclonal antibody toolkit for C. elegans. PLoS ONE. 2010;5:e10161 pubmed 出版商
产品信息
内部号码 :
6498
名称 :
LMP1
Depositor Name :
Nonet, M.L. / Hadwiger, G. / Dour, S.
Depositor Institution :
华盛顿大学医科学校
Date Deposited :
2/16/10
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
抗原 :
LMP-1
抗原物种 :
C. elegans
宿主物种 :
小鼠
抗体亚型 :
MIgG2b
Isotype for catalog (legacy) :
IgG2b
Positive Tested Species Reactivity :
C. elegans
Species Tested (legacy) :
C. elegans
Initial Publication Pubmed ID :
20405020
Depositor Notes (Special Instructions) :
Works on C. elegans whole mounts. Stains lysosomes. Specific by western blot: the 37 kDa band observed in wild type is absent from the lmp-1 mutant (nr2045). On whole mount immunostaining, most of the wild type staining is lost in the lmp-1 mutant (nr2045) except that the immunostaining of the nervous system remained in the mutant and became more pronounced, suggesting some cross reaction with another LAMP protein (see initial publication).
Collections :
C. elegans
搜索关键词 :
Nonet, M.L. / Hadwiger, G. / Dour, S., LMP-1, C. elegans, MIgG2b, C. elegans, LMP-1, , AB_2161795, monoclonal, C. elegans, Immunofluorescence/Western Blot
抗原分子量 :
Predicted: 24 kDa; Apparent: 37 kDa
基因 :
LMP-1
UniProt数据库编号 :
Q11117
抗体登记处号码 :
AB_2161795
Synonyms (Alternate Clone Names) :
2E2
免疫原 :
Recombinant His6-tagged LMP-1 (N-terminal aa 1-143 of mature LMP-1) fusion protein
免疫原序列 :
Partial protein
克隆性 :
单克隆
Myeloma Strain :
P3X63Ag8.653
表位定位 :
Yes
Epitope Location or Sequence :
N-terminal aa 1-143 of mature LMP-1
表位定位Pubmed登录号 :
20405020
Recommended Applications :
免疫荧光, 免疫印迹
Immunoblotting (legacy) :
good
免疫荧光PubMed IDs :
20405020 25922527
免疫印迹PubMed IDs :
20405020 23458156 26596346
其他信息 :
The LAMP family protein lmp-1 is a homolog of the lysosome associated membrane protein family (LAMPs) and is highly expressed and localized to lysosomal-like granules in the C. elegans intestine which can be detected in wild type animals.
DSHB增长培养基 :
Iscove's
References (legacy) :
Hadwiger, G., Dour, S., Arur, S., Fox, P., and Nonet, M.L. (2010) A monoclonal antibody toolkit for C. elegans. PLoS One. 5(4):e10161-10115.
公司信息
Developmental Studies Hybridoma Bank
University of Iowa
dshb@uiowa.edu
http://dshb.biology.uiowa.edu
公司总部: 美国
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构,为生命科学研究领域及诊断领域,提供高质量的抗体等产品。