产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
抗肌萎缩蛋白, 外显子31/32
目录 :
MANDYS1(3B7)
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
MANDYS1(3B7)
反应物种 :
人类, 小鼠, ,
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 免疫沉淀
文章摘录数: 20
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 3
Toral Ojeda I, Aldanondo G, Lasa Elgarresta J, Lasa Fernández H, Fernandez Torron R, Lopez de Munain A, et al. Calpain 3 deficiency affects SERCA expression and function in the skeletal muscle. Expert Rev Mol Med. 2016;18:e7 pubmed 出版商
  • 免疫印迹; 小鼠; 1:200; 图 5
Parvatiyar M, Marshall J, Nguyen R, Jordan M, Richardson V, Roos K, et al. Sarcospan Regulates Cardiac Isoproterenol Response and Prevents Duchenne Muscular Dystrophy-Associated Cardiomyopathy. J Am Heart Assoc. 2015;4: pubmed 出版商
  • 免疫细胞化学; 小鼠
Fajardo V, Bombardier E, McMillan E, TRAN K, Wadsworth B, Gamu D, et al. Phospholamban overexpression in mice causes a centronuclear myopathy-like phenotype. Dis Model Mech. 2015;8:999-1009 pubmed 出版商
  • 免疫印迹; 小鼠; 1:200; 图 4
Marshall J, Oh J, Chou E, Lee J, Holmberg J, Burkin D, et al. Sarcospan integration into laminin-binding adhesion complexes that ameliorate muscular dystrophy requires utrophin and α7 integrin. Hum Mol Genet. 2015;24:2011-22 pubmed 出版商
  • 免疫印迹; 鸡; 1:5
Wahlin K, Moreira E, Huang H, Yu N, Adler R. Molecular dynamics of photoreceptor synapse formation in the developing chick retina. J Comp Neurol. 2008;506:822-37 pubmed
Hutton K, Vaughn M, Litta G, Turner B, Starkey J. Effect of vitamin D status improvement with 25-hydroxycholecalciferol on skeletal muscle growth characteristics and satellite cell activity in broiler chickens. J Anim Sci. 2014;92:3291-9 pubmed 出版商
Kodippili K, Vince L, Shin J, Yue Y, Morris G, McIntosh M, et al. Characterization of 65 epitope-specific dystrophin monoclonal antibodies in canine and murine models of duchenne muscular dystrophy by immunostaining and western blot. PLoS ONE. 2014;9:e88280 pubmed 出版商
Le T, Nguyen T, Morris G. Monoclonal antibodies for clinical trials of Duchenne muscular dystrophy therapy. Neuromuscul Disord. 2014;24:195-200 pubmed 出版商
Hines E, Coffey J, Starkey C, Chung T, Starkey J. Improvement of maternal vitamin D status with 25-hydroxycholecalciferol positively impacts porcine fetal skeletal muscle development and myoblast activity. J Anim Sci. 2013;91:4116-22 pubmed 出版商
Morris G, Man N, Sewry C. Monitoring duchenne muscular dystrophy gene therapy with epitope-specific monoclonal antibodies. Methods Mol Biol. 2011;709:39-61 pubmed 出版商
Coovert D, Le T, Morris G, Man N, Kralewski M, Sendtner M, et al. Does the survival motor neuron protein (SMN) interact with Bcl-2?. J Med Genet. 2000;37:536-9 pubmed
Hori S, Ohtani S, Nguyen T, Morris G. The N-terminal half of dystrophin is protected from proteolysis in situ. Biochem Biophys Res Commun. 1995;209:1062-7 pubmed
Nguyen T, Morris G. Use of epitope libraries to identify exon-specific monoclonal antibodies for characterization of altered dystrophins in muscular dystrophy. Am J Hum Genet. 1993;52:1057-66 pubmed
Mendell J, Kissel J, Amato A, King W, Signore L, Prior T, et al. Myoblast transfer in the treatment of Duchenne's muscular dystrophy. N Engl J Med. 1995;333:832-8 pubmed
Sedgwick S, Nguyen T, Ellis J, Crowne H, Morris G. Rapid mapping by transposon mutagenesis of epitopes on the muscular dystrophy protein, dystrophin. Nucleic Acids Res. 1991;19:5889-94 pubmed
Nguyen thi Man -, Cartwright A, Morris G, Love D, Bloomfield J, Davies K. Monoclonal antibodies against defined regions of the muscular dystrophy protein, dystrophin. FEBS Lett. 1990;262:237-40 pubmed
Yarom R, Morris G, Froede R, Schaper J. Myocardial dystrophin immunolocalization at sarcolemma and transverse tubules. Experientia. 1992;48:614-6 pubmed
Lederfein D, Levy Z, Augier N, Mornet D, Morris G, Fuchs O, et al. A 71-kilodalton protein is a major product of the Duchenne muscular dystrophy gene in brain and other nonmuscle tissues. Proc Natl Acad Sci U S A. 1992;89:5346-50 pubmed
Dickson G, Azad A, Morris G, Simon H, Noursadeghi M, Walsh F. Co-localization and molecular association of dystrophin with laminin at the surface of mouse and human myotubes. J Cell Sci. 1992;103 ( Pt 4):1223-33 pubmed
Nguyen T, Ginjaar I, van Ommen G, Morris G. Monoclonal antibodies for dystrophin analysis. Epitope mapping and improved binding to SDS-treated muscle sections. Biochem J. 1992;288 ( Pt 2):663-8 pubmed
产品信息
内部号码 :
3724
名称 :
MANDYS1(3B7)
Depositor Name :
Morris, G.E.
Depositor Institution :
Wolfson Centre for Inherited Neuromuscular Disease, RJAH Orthopaedic Hospital, Oswestry, UK
Date Deposited :
10/26/05
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
抗原 :
抗肌萎缩蛋白, 外显子31/32
抗原物种 :
人类
宿主物种 :
小鼠
抗体亚型 :
MIgG2a
Isotype for catalog (legacy) :
IgG2a
Positive Tested Species Reactivity :
狗, 人类, 小鼠, 猪, 兔
Species Tested (legacy) :
人类, 小鼠, 狗, 猪和兔
Initial Publication Pubmed ID :
1692289
Depositor Notes (Special Instructions) :
This antibody does not work with Xenopus
搜索关键词 :
Morris, dystrophin, exons 31/32, DMD, BMD, CMD3B, MRX85, monoclonal, AB_528206 AB_2314003 AB_2618153, IgG2a, Canine,Human,Mouse,Pig,Rabbit, ELISA,Immunofluorescence,Immunoprecipitation,Western Blot
抗原分子量 :
Predicted: 427 kDa; Apparent: 427 kDa
基因 :
DMD
Alternate Gene Name(s) :
BMD, CMD3B, MRX85
UniProt数据库编号 :
P11532
抗体登记处号码 :
AB_528206 AB_2314003 AB_2618153
免疫原 :
Recombinant LacZ/dystrophin (aa 816-1749, rod domain of isoform 4 (Uniprot ID P11532-1)) fusion protein
免疫原序列 :
Partial protein
克隆性 :
单克隆
Myeloma Strain :
NS0或Sp2/0
表位定位 :
Yes
Epitope Location or Sequence :
exons 31/32, aa 1431-1505 (repeats 10 and 11 of the central rod domain)
表位定位Pubmed登录号 :
7684887
Recommended Applications :
酶联免疫吸附测定, 免疫荧光, 免疫沉淀, 免疫印迹
Immunoblotting (legacy) :
27444300
免疫荧光PubMed IDs :
1692289 23893976 7684887 24361045 24516626 21194020 7651473 1612140 1283164
免疫印迹PubMed IDs :
1692289 24516626 21194020 1719482 1283164 1319059
免疫沉淀PubMed IDs :
21194020 1283164 1319059 10970187
酶联免疫吸附测定PubMed IDs :
1692289
PubMed IDs :
7684887 1281410 7733959
Additional Characterization :
http://www.glennmorris.org.uk/datasheets/MANDYS1(3B7).doc
DSHB增长培养基 :
Iscove's
References (legacy) :
FEBS Lett. 262, 237-240.; Am. J. Hum. Genet. 52, 1057-1066.; J. Anim. Sci. 91, 4116-4122.; J. Anim. Sci 92(8), 3291-3299.
公司信息
Developmental Studies Hybridoma Bank
University of Iowa
dshb@uiowa.edu
http://dshb.biology.uiowa.edu
公司总部: 美国
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构,为生命科学研究领域及诊断领域,提供高质量的抗体等产品。