抗肌萎缩蛋白, 外显子21 | Developmental Studies Hybridoma Bank MANDYS19(8F6) 产品信息

产品简要

公司名称 :

Developmental Studies Hybridoma Bank

产品类型 :

抗体

产品名称 :

抗肌萎缩蛋白, 外显子21

MANDYS19(8F6)

克隆性 :

单克隆

宿主 :

小鼠

共轭标签 :

未共轭

克隆名称 :

MANDYS19(8F6)

反应物种 :

人类, 小鼠, 狗, 鸡

应用 :

免疫印迹, 酶联免疫吸附测定, 免疫细胞化学

文章摘录数: 11

出版应用/物种/样本/稀释	参考文献
免疫印迹; 鸡; 1:5	Wahlin K, Moreira E, Huang H, Yu N, Adler R. Molecular dynamics of photoreceptor synapse formation in the developing chick retina. J Comp Neurol. 2008;506:822-37 pubmed
	MassouridÃ¨s E, Polentes J, Mangeot P, Mournetas V, Nectoux J, Deburgrave N, et al. Dp412e: a novel human embryonic dystrophin isoform induced by BMP4 in early differentiated cells. Skelet Muscle. 2015;5:40 pubmed 出版商
	Kodippili K, Vince L, Shin J, Yue Y, Morris G, McIntosh M, et al. Characterization of 65 epitope-specific dystrophin monoclonal antibodies in canine and murine models of duchenne muscular dystrophy by immunostaining and western blot. PLoS ONE. 2014;9:e88280 pubmed 出版商
	Le T, Nguyen T, Morris G. Monoclonal antibodies for clinical trials of Duchenne muscular dystrophy therapy. Neuromuscul Disord. 2014;24:195-200 pubmed 出版商
	Morris G, Man N, Sewry C. Monitoring duchenne muscular dystrophy gene therapy with epitope-specific monoclonal antibodies. Methods Mol Biol. 2011;709:39-61 pubmed 出版商
	Lu Q, Morris G, Wilton S, Ly T, Artem yeva O, Strong P, et al. Massive idiosyncratic exon skipping corrects the nonsense mutation in dystrophic mouse muscle and produces functional revertant fibers by clonal expansion. J Cell Biol. 2000;148:985-96 pubmed
	Hori S, Ohtani S, Nguyen T, Morris G. The N-terminal half of dystrophin is protected from proteolysis in situ. Biochem Biophys Res Commun. 1995;209:1062-7 pubmed
	Nguyen T, Morris G. Use of epitope libraries to identify exon-specific monoclonal antibodies for characterization of altered dystrophins in muscular dystrophy. Am J Hum Genet. 1993;52:1057-66 pubmed
	Sedgwick S, Nguyen T, Ellis J, Crowne H, Morris G. Rapid mapping by transposon mutagenesis of epitopes on the muscular dystrophy protein, dystrophin. Nucleic Acids Res. 1991;19:5889-94 pubmed
	Nguyen thi Man -, Cartwright A, Morris G, Love D, Bloomfield J, Davies K. Monoclonal antibodies against defined regions of the muscular dystrophy protein, dystrophin. FEBS Lett. 1990;262:237-40 pubmed
	Nguyen T, Ginjaar I, van Ommen G, Morris G. Monoclonal antibodies for dystrophin analysis. Epitope mapping and improved binding to SDS-treated muscle sections. Biochem J. 1992;288 ( Pt 2):663-8 pubmed

产品信息

内部号码 :

3795

名称 :

MANDYS19(8F6)

Depositor Name :

Morris, G.E.

Depositor Institution :

Wolfson Centre for Inherited Neuromuscular Disease, RJAH Orthopaedic Hospital, Oswestry, UK

Date Deposited :

7/13/06

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

抗原 :

抗肌萎缩蛋白, 外显子21

抗原物种 :

人类

宿主物种 :

小鼠

抗体亚型 :

MIgG1

Isotype for catalog (legacy) :

IgG1

Positive Tested Species Reactivity :

狗, 人类, 小鼠

Species Tested (legacy) :

human and mouse (not chick, torpedo)

Initial Publication Pubmed ID :

1692289

Depositor Notes (Special Instructions) :

This antibody does not work with chicken or torpedo

Collections :

人类, 肌营养不良, 骨骼肌

搜索关键词 :

Morris, dystrophin, , exon 21, MANDYS19, DMD, BMD, CMD3B, MRX85, monoclonal, human, AB_2618169, IgG1, Canine,Human,Mouse, ELISA,Immunofluorescence,Western Blot

抗原分子量 :

Predicted: 427 kDa; Apparent: 427 kDa

基因 :

DMD

Alternate Gene Name(s) :

BMD, CMD3B, MRX85

UniProt数据库编号 :

P11532

抗体登记处号码 :

AB_2618169

免疫原 :

Recombinant LacZ/dystrophin (aa 816-1749, rod domain of isoform 4 (Uniprot ID P11532-1)) fusion protein

免疫原序列 :

Partial protein

克隆性 :

单克隆

Myeloma Strain :

NS0或Sp2/0

表位定位 :

Yes

Epitope Location or Sequence :

exon 21. aa 901-904 (GQGP) of isoform 4 (Uniprot ID P11532-1)

表位定位Pubmed登录号 :

7684887 24361045

Recommended Applications :

酶联免疫吸附测定, 免疫荧光, 免疫印迹

Immunoblotting (legacy) :

Yes

免疫荧光PubMed IDs :

1692289 24516626 21194020 10704448

免疫印迹PubMed IDs :

1692289 24516626 21194020 1719482 26568816

酶联免疫吸附测定PubMed IDs :

1692289

PubMed IDs :

7684887 1281410 7733959

Additional Characterization :

http://www.glennmorris.org.uk/datasheets/MANDYS19(8F6).doc

DSHB增长培养基 :

Iscove's

References (legacy) :

FEBS Lett. 262, 237-240.; Am. J. Hum. Genet. 52, 1057-1066.

公司信息

Developmental Studies Hybridoma Bank

University of Iowa

dshb@uiowa.edu

http://dshb.biology.uiowa.edu

公司总部: 美国

Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构，为生命科学研究领域及诊断领域，提供高质量的抗体等产品。

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