产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
TRP protein (transient receptor potential)
目录 :
MAb83F6
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
MAb83F6
反应物种 :
黑腹果蝇
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀
更多信息或购买 :
Developmental Studies Hybridoma Bank 产品网页
文章摘录数: 13
参考文献
Fritsch C, Bernardo Garcia F, Humberg T, Mishra A, Miellet S, Almeida S, et al. Multilevel regulation of the glass locus during Drosophila eye development. PLoS Genet. 2019;15:e1008269 pubmed 出版商
Voolstra O, Rhodes Mordov E, Katz B, Bartels J, Oberegelsbacher C, Schotthöfer S, et al. The Phosphorylation State of the Drosophila TRP Channel Modulates the Frequency Response to Oscillating Light In Vivo. J Neurosci. 2017;37:4213-4224 pubmed 出版商
Cerny A, Altendorfer A, Schopf K, Baltner K, Maag N, Sehn E, et al. The GTP- and Phospholipid-Binding Protein TTD14 Regulates Trafficking of the TRPL Ion Channel in Drosophila Photoreceptor Cells. PLoS Genet. 2015;11:e1005578 pubmed 出版商
Voolstra O, Bartels J, Oberegelsbacher C, Pfannstiel J, Huber A. Phosphorylation of the Drosophila transient receptor potential ion channel is regulated by the phototransduction cascade and involves several protein kinases and phosphatases. PLoS ONE. 2013;8:e73787 pubmed 出版商
Katz B, Oberacker T, Richter D, Tzadok H, Peters M, Minke B, et al. Drosophila TRP and TRPL are assembled as homomultimeric channels in vivo. J Cell Sci. 2013;126:3121-33 pubmed 出版商
Richter D, Katz B, Oberacker T, Tzarfaty V, Belusic G, Minke B, et al. Translocation of the Drosophila transient receptor potential-like (TRPL) channel requires both the N- and C-terminal regions together with sustained Ca2+ entry. J Biol Chem. 2011;286:34234-43 pubmed 出版商
Sanxaridis P, Tsunoda S. A forward genetic screen in Drosophila melanogaster to identify mutations affecting INAD localization in photoreceptor cells. Fly (Austin). 2010;4:95-103 pubmed
Voolstra O, Beck K, Oberegelsbacher C, Pfannstiel J, Huber A. Light-dependent phosphorylation of the drosophila transient receptor potential ion channel. J Biol Chem. 2010;285:14275-84 pubmed 出版商
Parnas M, Katz B, Lev S, Tzarfaty V, Dadon D, Gordon Shaag A, et al. Membrane lipid modulations remove divalent open channel block from TRP-like and NMDA channels. J Neurosci. 2009;29:2371-83 pubmed 出版商
Meyer N, Oberegelsbacher C, Dürr T, Schäfer A, Huber A. An eGFP-based genetic screen for defects in light-triggered subcelluar translocation of the Drosophila photoreceptor channel TRPL. Fly (Austin). 2008;2:36-46 pubmed
Cheng Y, Nash H. Drosophila TRP channels require a protein with a distinctive motif encoded by the inaF locus. Proc Natl Acad Sci U S A. 2007;104:17730-4 pubmed
Gillo B, Chorna I, Cohen H, Cook B, Manistersky I, Chorev M, et al. Coexpression of Drosophila TRP and TRP-like proteins in Xenopus oocytes reconstitutes capacitative Ca2+ entry. Proc Natl Acad Sci U S A. 1996;93:14146-51 pubmed
Pollock J, Assaf A, Peretz A, Nichols C, Mojet M, Hardie R, et al. TRP, a protein essential for inositide-mediated Ca2+ influx is localized adjacent to the calcium stores in Drosophila photoreceptors. J Neurosci. 1995;15:3747-60 pubmed
产品信息
内部号码 :
921
名称 :
MAb83F6
Depositor Name :
Benzer, S.
Depositor Institution :
California Institute of Technology
Date Deposited :
7/27/05
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
抗原 :
TRP protein (transient receptor potential)
抗原物种 :
果蝇
宿主物种 :
小鼠
抗体亚型 :
MIgG1, kappa light chain
Isotype for catalog (legacy) :
IgG1, kappa light chain
Positive Tested Species Reactivity :
果蝇
Species Tested (legacy) :
果蝇
Initial Publication Pubmed ID :
7751943
Depositor Notes (Special Instructions) :
Overfixation reduces the efficacy of MAb83F6
Collections :
Cell signaling,Drosophila antigens,Neurodevelopment,Skeletal muscle
搜索关键词 :
Benzer, S., TRP protein (transient receptor potential), Drosophila, MIgG1, kappa light chain, Drosophila, trp, CG7875, 559, AB_528496, monoclonal, Cell signaling/Drosophila antigens/Skeletal muscle/Neurodevelopment, Immunofluorescence/Western Blot/Immunoprecipitation
抗原分子量 :
Predicted: 143 kDa; Apparent: 143 kDa
基因 :
trp
Alternate Gene Name(s) :
CG7875, 559
UniProt数据库编号 :
P19334
抗体登记处号码 :
AB_528496
免疫原 :
Purified rhabdomeres from Drosophila eyes.
免疫原序列 :
全长蛋白
克隆性 :
单克隆
表位定位 :
Yes
Epitope Location or Sequence :
Intracellular C-terminal (aa 675-1275)
表位定位Pubmed登录号 :
23687378
Recommended Applications :
免疫荧光, 免疫沉淀, 免疫印迹
Immunoblotting (legacy) :
Yes
免疫荧光PubMed IDs :
7751943 20215118 17968007 23687378 24040070 26509977
免疫印迹PubMed IDs :
7751943 8943075 19244513 20215118 17968007 23687378 21816824 18820462 20404479 26509977
免疫沉淀PubMed IDs :
20215118 23687378
其他信息 :
Doesn't stain null trp fly mutants. trp is a transmembrane light-sensitive calcium channel required for phototransduction.
DSHB增长培养基 :
RPMI
References (legacy) :
J. Neurosci. 15(5), 3747-3760.; Proc. Natl. Acad. Sci. USA 93(24), 14146-14151.; J. Neurosci. 29(8), 2371-2383.
更多信息或购买 :
Developmental Studies Hybridoma Bank 产品网页
公司信息
Developmental Studies Hybridoma Bank
University of Iowa
dshb@uiowa.edu
http://dshb.biology.uiowa.edu
公司总部: 美国
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构，为生命科学研究领域及诊断领域，提供高质量的抗体等产品。