产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
myosin-VIIa, unconventional
目录 :
MYO7A 138-1
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
MYO7A 138-1
反应物种 :
gerbils, zebra finch, Trachemys scripta elegans, 人类, 小鼠, 大鼠, , 斑马鱼, 果蝇
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-冰冻切片
文章摘录数: 15
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; 果蝇; 1:100; 图 5
  • 免疫印迹; 果蝇; 1:10; 图 5
Li T, Giagtzoglou N, Eberl D, Jaiswal S, Cai T, Godt D, et al. The E3 ligase Ubr3 regulates Usher syndrome and MYH9 disorder proteins in the auditory organs of Drosophila and mammals. elife. 2016;5: pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:2000
Scheffer D, Shen J, Corey D, Chen Z. Gene Expression by Mouse Inner Ear Hair Cells during Development. J Neurosci. 2015;35:6366-80 pubmed 出版商
  • 免疫组化; 小鼠; 1:100
  • 免疫组化; Trachemys scripta elegans; 1:100
  • 免疫印迹; Trachemys scripta elegans
  • 免疫组化; zebra finch; 1:100
Jordan P, Fettis M, Holt J. Efferent innervation of turtle semicircular canal cristae: comparisons with bird and mouse. J Comp Neurol. 2015;523:1258-80 pubmed 出版商
  • 免疫组化; gerbils; 1:20
  • 免疫组化; 大鼠; 1:20
Pujol R, Pickett S, Nguyen T, Stone J. Large basolateral processes on type II hair cells are novel processing units in mammalian vestibular organs. J Comp Neurol. 2014;522:3141-59 pubmed 出版商
Sirko P, Gale J, Ashmore J. Intercellular Ca2+ signalling in the adult mouse cochlea. J Physiol. 2019;597:303-317 pubmed 出版商
Pei W, Xu L, Huang S, Pettie K, Idol J, Rissone A, et al. Guided genetic screen to identify genes essential in the regeneration of hair cells and other tissues. NPJ Regen Med. 2018;3:11 pubmed 出版商
Breglio A, Rusheen A, Shide E, Fernandez K, Spielbauer K, McLachlin K, et al. Cisplatin is retained in the cochlea indefinitely following chemotherapy. Nat Commun. 2017;8:1654 pubmed 出版商
Pei W, Xu L, Varshney G, Carrington B, Bishop K, Jones M, et al. Additive reductions in zebrafish PRPS1 activity result in a spectrum of deficiencies modeling several human PRPS1-associated diseases. Sci Rep. 2016;6:29946 pubmed 出版商
Shin J, Krey J, Hassan A, Metlagel Z, Tauscher A, Pagana J, et al. Molecular architecture of the chick vestibular hair bundle. Nat Neurosci. 2013;16:365-74 pubmed 出版商
Yariz K, Duman D, Zazo Seco C, Dallman J, Huang M, Peters T, et al. Mutations in OTOGL, encoding the inner ear protein otogelin-like, cause moderate sensorineural hearing loss. Am J Hum Genet. 2012;91:872-82 pubmed 出版商
Burns J, Yoo J, Atala A, Jackson J. MYC gene delivery to adult mouse utricles stimulates proliferation of postmitotic supporting cells in vitro. PLoS ONE. 2012;7:e48704 pubmed 出版商
Freyer L, Aggarwal V, Morrow B. Dual embryonic origin of the mammalian otic vesicle forming the inner ear. Development. 2011;138:5403-14 pubmed 出版商
Francis S, Kramarenko I, Brandon C, Lee F, Baker T, Cunningham L. Celastrol inhibits aminoglycoside-induced ototoxicity via heat shock protein 32. Cell Death Dis. 2011;2:e195 pubmed 出版商
Demontis F, Dahmann C. Characterization of the Drosophila ortholog of the human Usher Syndrome type 1G protein sans. PLoS ONE. 2009;4:e4753 pubmed 出版商
Soni L, Warren C, Bucci C, Orten D, Hasson T. The unconventional myosin-VIIa associates with lysosomes. Cell Motil Cytoskeleton. 2005;62:13-26 pubmed
产品信息
内部号码 :
3933
名称 :
MYO7A 138-1
Depositor Name :
Orten, D.J.
Depositor Institution :
Boys Town National Research Hospital
Date Deposited :
11/1/07
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
抗原 :
myosin-VIIa, unconventional
抗原物种 :
人类
宿主物种 :
小鼠
抗体亚型 :
MIgG1, kappa light chain
Isotype for catalog (legacy) :
IgG1, kappa light chain
Positive Tested Species Reactivity :
鸡, 人类, 小鼠, 大鼠, 斑马鱼
Species Tested (legacy) :
reacts with all animals tested: human, mouse, rat, and chicken
Initial Publication Pubmed ID :
16001398
Depositor Notes (Special Instructions) :
Mutations in this antigen lead to the human condition Usher syndrome 1B.
Collections :
细胞骨架, 人类, 骨骼肌
搜索关键词 :
Dana Jo Orten, myosin-VIIa, unconventional, Human, MIgG1, kappa light chain, human/mouse/rat/chicken, MYO7A , DFNA11, DFNB2, NSRD2, USH1B, AB_2282417, Monoclonal, Human/Cytoskeletal elements, Immunohistochemistry/Immunofluorescence/Western blot
抗原分子量 :
240 kDa
基因 :
MYO7A
Alternate Gene Name(s) :
DFNA11, DFNB2, NSRD2, USH1B
UniProt数据库编号 :
Q13402
抗体登记处号码 :
AB_2282417
免疫原 :
合成肽
免疫原序列 :
a.a。 927-1203
克隆性 :
单克隆
Myeloma Strain :
MOPC-21 NS-1
表位定位 :
Yes
Epitope Location or Sequence :
a.a。 927-1203
表位定位Pubmed登录号 :
16001398
Recommended Applications :
免疫荧光, 免疫组化, 免疫印迹
Immunoblotting (legacy) :
Yes
免疫组化PubMed IDs :
23119091 22110056 29162831
免疫荧光PubMed IDs :
16001398 27425195 25560461 27425195 26809054
免疫印迹PubMed IDs :
16001398
免疫沉淀PubMed IDs :
16001398
其他信息 :
RRID:AB_2282417
DSHB增长培养基 :
RPMI
References (legacy) :
Cell Motil. Cytoskeleton 62(1), 13-26.
公司信息
Developmental Studies Hybridoma Bank
University of Iowa
dshb@uiowa.edu
http://dshb.biology.uiowa.edu
公司总部: 美国
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构,为生命科学研究领域及诊断领域,提供高质量的抗体等产品。