整合素乙1(CD29), 人类 | Developmental Studies Hybridoma Bank P5D2 产品信息

产品简要

公司名称 :

Developmental Studies Hybridoma Bank

产品类型 :

抗体

产品名称 :

整合素乙1(CD29), 人类

P5D2

克隆性 :

单克隆

宿主 :

小鼠

共轭标签 :

未共轭

克隆名称 :

P5D2

反应物种 :

人类, 小鼠

应用 :

免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 流式细胞仪, 抑制或激活实验, 免疫印迹基因敲除验证

文章摘录数: 28

出版应用/物种/样本/稀释	参考文献
免疫细胞化学; 人类; 1:200; 图 4h	Sahgal P, Alanko J, Icha J, Paatero I, Hamidi H, Arjonen A, et al. GGA2 and RAB13 promote activity-dependent β1-integrin recycling. J Cell Sci. 2019;132: pubmed 出版商
免疫印迹基因敲除验证; 小鼠; 1:17; 图 2c	Huet Calderwood C, Rivera Molina F, Iwamoto D, Kromann E, Toomre D, Calderwood D. Novel ecto-tagged integrins reveal their trafficking in live cells. Nat Commun. 2017;8:570 pubmed 出版商
免疫细胞化学; 人类; 1:100; 图 s4	Qi L, Jafari N, Li X, Chen Z, Li L, Hytönen V, et al. Talin2-mediated traction force drives matrix degradation and cell invasion. J Cell Sci. 2016;129:3661-3674 pubmed
流式细胞仪; 人类	Iwai L, Payne L, Luczynski M, Chang F, Xu H, Clinton R, et al. Phosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation downstream of wild-type DDR2 and its lung cancer mutants. Biochem J. 2013;454:501-13 pubmed 出版商
抑制或激活实验; 人类; 10 ug/ml 免疫细胞化学; 人类; 10 ug/ml; 图 s9f	Xu H, Bihan D, Chang F, Huang P, Farndale R, Leitinger B. Discoidin domain receptors promote Î±1Î²1- and Î±2Î²1-integrin mediated cell adhesion to collagen by enhancing integrin activation. PLoS ONE. 2012;7:e52209 pubmed 出版商
	Bekier M, Wang L, Li J, Huang H, Tang D, Zhang X, et al. Knockout of the Golgi stacking proteins GRASP55 and GRASP65 impairs Golgi structure and function. Mol Biol Cell. 2017;28:2833-2842 pubmed 出版商
	Hou S, Isaji T, Hang Q, Im S, Fukuda T, Gu J. Distinct effects of Î²1 integrin on cell proliferation and cellular signaling in MDA-MB-231 breast cancer cells. Sci Rep. 2016;6:18430 pubmed 出版商
	Isaji T, Im S, Gu W, Wang Y, Hang Q, Lu J, et al. An oncogenic protein Golgi phosphoprotein 3 up-regulates cell migration via sialylation. J Biol Chem. 2014;289:20694-705 pubmed
	Flannagan R, Canton J, Furuya W, Glogauer M, Grinstein S. The phosphatidylserine receptor TIM4 utilizes integrins as coreceptors to effect phagocytosis. Mol Biol Cell. 2014;25:1511-22 pubmed 出版商
	Hämälistö S, Pouwels J, De Franceschi N, Saari M, Ivarsson Y, Zimmermann P, et al. A ZO-1/?5?1-integrin complex regulates cytokinesis downstream of PKC? in NCI-H460 cells plated on fibronectin. PLoS ONE. 2013;8:e70696 pubmed 出版商
	Xiang Y, Zhang X, Nix D, Katoh T, Aoki K, Tiemeyer M, et al. Regulation of protein glycosylation and sorting by the Golgi matrix proteins GRASP55/65. Nat Commun. 2013;4:1659 pubmed 出版商
	Lee J, Ballikaya S, Schonig K, Ball C, Glimm H, Kopitz J, et al. Transforming growth factor beta receptor 2 (TGFBR2) changes sialylation in the microsatellite unstable (MSI) Colorectal cancer cell line HCT116. PLoS ONE. 2013;8:e57074 pubmed 出版商
	Taubenberger A, Quent V, Thibaudeau L, Clements J, Hutmacher D. Delineating breast cancer cell interactions with engineered bone microenvironments. J Bone Miner Res. 2013;28:1399-411 pubmed 出版商
	Gautrot J, Wang C, Liu X, Goldie S, Trappmann B, Huck W, et al. Mimicking normal tissue architecture and perturbation in cancer with engineered micro-epidermis. Biomaterials. 2012;33:5221-9 pubmed 出版商
	Mai A, Veltel S, Pellinen T, Padzik A, Coffey E, Marjomaki V, et al. Competitive binding of Rab21 and p120RasGAP to integrins regulates receptor traffic and migration. J Cell Biol. 2011;194:291-306 pubmed 出版商
	Xia B, Joubert A, Groves B, Vo K, Ashraf D, Djavaherian D, et al. Modulation of cell adhesion and migration by the histone methyltransferase subunit mDpy-30 and its interacting proteins. PLoS ONE. 2010;5:e11771 pubmed 出版商
	Rowland T, Miller L, Blaschke A, Doss E, Bonham A, Hikita S, et al. Roles of integrins in human induced pluripotent stem cell growth on Matrigel and vitronectin. Stem Cells Dev. 2010;19:1231-40 pubmed 出版商
	Vascotto S, Griffith M. Localization of candidate stem and progenitor cell markers within the human cornea, limbus, and bulbar conjunctiva in vivo and in cell culture. Anat Rec A Discov Mol Cell Evol Biol. 2006;288:921-31 pubmed
	Muenzner P, Rohde M, Kneitz S, Hauck C. CEACAM engagement by human pathogens enhances cell adhesion and counteracts bacteria-induced detachment of epithelial cells. J Cell Biol. 2005;170:825-36 pubmed
	Levesque J, Takada Y, Puzon McLaughlin W, Simmons P. A novel monoclonal antibody recognizing a cation-dependent epitope within the regulatory loop of human beta(1) integrin (CD29). Hybrid Hybridomics. 2002;21:253-60 pubmed
	Setty S, Kim Y, Fields G, Clegg D, Wayner E, Tsilibary E. Interactions of type IV collagen and its domains with human mesangial cells. J Biol Chem. 1998;273:12244-9 pubmed
	Skubitz A, Bast R, Wayner E, Letourneau P, Wilke M. Expression of alpha 6 and beta 4 integrins in serous ovarian carcinoma correlates with expression of the basement membrane protein laminin. Am J Pathol. 1996;148:1445-61 pubmed
	Skubitz A, Grossman M, McCarthy J, Wayner E, Cameron J. The decreased adhesion of Y79 retinoblastoma cells to extracellular matrix proteins is due to a deficit of integrin receptors. Invest Ophthalmol Vis Sci. 1994;35:2820-33 pubmed
	Dittel B, McCarthy J, Wayner E, LeBien T. Regulation of human B-cell precursor adhesion to bone marrow stromal cells by cytokines that exert opposing effects on the expression of vascular cell adhesion molecule-1 (VCAM-1). Blood. 1993;81:2272-82 pubmed
	Wyrick P, Davis C, Wayner E. Chlamydia trachomatis does not bind to alpha beta 1 integrins to colonize a human endometrial epithelial cell line cultured in vitro. Microb Pathog. 1994;17:159-66 pubmed
	Seltzer J, Lee A, Akers K, Sudbeck B, Southon E, Wayner E, et al. Activation of 72-kDa type IV collagenase/gelatinase by normal fibroblasts in collagen lattices is mediated by integrin receptors but is not related to lattice contraction. Exp Cell Res. 1994;213:365-74 pubmed
	Bhatia R, Wayner E, McGlave P, Verfaillie C. Interferon-alpha restores normal adhesion of chronic myelogenous leukemia hematopoietic progenitors to bone marrow stroma by correcting impaired beta 1 integrin receptor function. J Clin Invest. 1994;94:384-91 pubmed
	Joneckis C, Ackley R, Orringer E, Wayner E, Parise L. Integrin alpha 4 beta 1 and glycoprotein IV (CD36) are expressed on circulating reticulocytes in sickle cell anemia. Blood. 1993;82:3548-55 pubmed

产品信息

内部号码 :

1057

名称 :

P5D2

Depositor Name :

Wayner, E.A.

Depositor Institution :

Fred Hutchison Cancer Research Center

Date Deposited :

8/4/93

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

抗原 :

整合素乙1(CD29), 人类

抗原物种 :

人类

宿主物种 :

小鼠

抗体亚型 :

MIgG1

Isotype for catalog (legacy) :

IgG1

Positive Tested Species Reactivity :

人类

Species Tested (legacy) :

人类

Initial Publication Pubmed ID :

7683214

Depositor Notes (Special Instructions) :

Inhibits binding of beta1 integrins. This antibody doesn't appear to work for western blotting.

Collections :

CD antigens,Cell adhesion,Cell signaling,Extracellular matrix proteins,Human,Neurodevelopment

搜索关键词 :

Wayner, E.A., integrin beta-1 (CD29), human, Human, MIgG1, Human, ITGB1, CD29, GPIIA, FNRB, MDF2, MSK12, VLA-4beta, AB_528308, monoclonal, Cell adhesion/Cluster Determinant antigens/Human/Cell signaling/Extracellular matrix proteins/Neurodevelopment, Immunohistochemistry/Immunofluorescence/Immunoprecipitation/Function Blocking/FACS

抗原分子量 :

Multiple isoforms; Predicted: 87 to 92 kDa; Apparent: 120 kDa

基因 :

ITGB1

Alternate Gene Name(s) :

CD29, GPIIA, FNRB, MDF2, MSK12, VLA-4beta

UniProt数据库编号 :

P05556

抗体登记处号码 :

AB_528308

Synonyms (Alternate Clone Names) :

CD29

免疫原 :

Human epidermal keratinocytes

免疫原序列 :

全长蛋白

克隆性 :

单克隆

Myeloma Strain :

狐狸NY

表位定位 :

Yes

Epitope Location or Sequence :

NKGEVFNELVGK(a.a。 207-218)

表位定位Pubmed登录号 :

12193278

Recommended Applications :

FACS,Function Blocking,Immunofluorescence,Immunohistochemistry,Immunoprecipitation

Immunoblotting (legacy) :

免疫组化PubMed IDs :

8623916

免疫荧光PubMed IDs :

16779811 23967087

免疫沉淀PubMed IDs :

7505118 9575174 23552074 23468914

Function Blocking Pubmed IDs :

7535373 7683214 7519563 9575174 7518835 8188477 16115956 23362043 24895123

流式细胞仪PubMed IDs :

7505118 8623916 7518835 8188477 16115956 24895123

PubMed IDs :

19811096

DSHB增长培养基 :

RPMI

References (legacy) :

J. Cell Biol. 121, 1141-1152.; PLos ONE 8(2): e57074. doi:10.1371/journal.pone.0057074.

公司信息

Developmental Studies Hybridoma Bank

University of Iowa

dshb@uiowa.edu

http://dshb.biology.uiowa.edu

公司总部: 美国

Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构，为生命科学研究领域及诊断领域，提供高质量的抗体等产品。

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综述

β1整合素

产品类型