产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
Pax6
目录 :
PAX6
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
PAX6
反应物种 :
dime-store turtle, Spanish newt, Gallot's lizard, lepidosaurs, 人类, 小鼠, 大鼠, , 斑马鱼
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片, 免疫印迹基因敲除验证, 免疫细胞化学基因敲除验证
文章摘录数: 266
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:500; 图 2s1c
Mondal B, Jin H, Kallappagoudar S, Sedkov Y, Martinez T, Sentmanat M, et al. The histone deacetylase complex MiDAC regulates a neurodevelopmental gene expression program to control neurite outgrowth. elife. 2020;9: pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 1:200; 图 s1a
Trevino A, Sinnott Armstrong N, Andersen J, Yoon S, Huber N, Pritchard J, et al. Chromatin accessibility dynamics in a model of human forebrain development. Science. 2020;367: pubmed 出版商
  • 免疫组化; 小鼠; 2 ug/ml; 图 1f"
Webster M, Barnett B, Stanchfield M, Paris J, Webster S, Cooley Themm C, et al. Stimulation of Retinal Pigment Epithelium With an α7 nAChR Agonist Leads to Müller Glia Dependent Neurogenesis in the Adult Mammalian Retina. Invest Ophthalmol Vis Sci. 2019;60:570-579 pubmed 出版商
  • 免疫细胞化学基因敲除验证; 人类; 1:37; 图 1b
  • 免疫印迹基因敲除验证; 人类; 1:37; 图 1a
Hegge B, Sjøttem E, Mikkola I. Generation of a PAX6 knockout glioblastoma cell line with changes in cell cycle distribution and sensitivity to oxidative stress. BMC Cancer. 2018;18:496 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 1h
Gao Y, Wilson G, Bozaoglu K, Elefanty A, Stanley E, Dottori M, et al. Generation of RAB39B knockout isogenic human embryonic stem cell lines to model RAB39B-mediated Parkinson's disease. Stem Cell Res. 2018;28:161-164 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 图 1a
Jang S, Choubey S, Furchtgott L, Zou L, Doyle A, Menon V, et al. Dynamics of embryonic stem cell differentiation inferred from single-cell transcriptomics show a series of transitions through discrete cell states. elife. 2017;6: pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 s2b
Cruz Molina S, Respuela P, Tebartz C, Kolovos P, Nikolic M, Fueyo R, et al. PRC2 Facilitates the Regulatory Topology Required for Poised Enhancer Function during Pluripotent Stem Cell Differentiation. Cell Stem Cell. 2017;20:689-705.e9 pubmed 出版商
  • 免疫组化; 人类; 1:25; 图 2A
Geng Z, Walsh P, Truong V, Hill C, Ebeling M, Kapphahn R, et al. Generation of retinal pigmented epithelium from iPSCs derived from the conjunctiva of donors with and without age related macular degeneration. PLoS ONE. 2017;12:e0173575 pubmed 出版商
  • 免疫细胞化学; 人类; 表 1
Zhu J, Cifuentes H, Reynolds J, Lamba D. Immunosuppression via Loss of IL2rγ Enhances Long-Term Functional Integration of hESC-Derived Photoreceptors in the Mouse Retina. Cell Stem Cell. 2017;20:374-384.e5 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 6e
Fujimura K, Mitsuhashi T, Shibata S, Shimozato S, Takahashi T. In Utero Exposure to Valproic Acid Induces Neocortical Dysgenesis via Dysregulation of Neural Progenitor Cell Proliferation/Differentiation. J Neurosci. 2016;36:10908-10919 pubmed
  • 免疫细胞化学; 人类; 1:1000; 图 1
Borgs L, Peyre E, Alix P, Hanon K, Grobarczyk B, Godin J, et al. Dopaminergic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects. Sci Rep. 2016;6:33377 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1e
Zhang L, Hua Q, Tang K, Shi C, Xie X, Zhang R. CXCR4 activation promotes differentiation of human embryonic stem cells to neural stem cells. Neuroscience. 2016;337:88-97 pubmed 出版商
  • 免疫组化; 小鼠; 1:5; 图 3
Gygli P, Chang J, Gokozan H, Catacutan F, Schmidt T, Kaya B, et al. Cyclin A2 promotes DNA repair in the brain during both development and aging. Aging (Albany NY). 2016;8:1540-70 pubmed 出版商
  • 免疫组化-冰冻切片; 鸡; 1:50; 图 2
Peretz Y, Eren N, Kohl A, Hen G, Yaniv K, Weisinger K, et al. A new role of hindbrain boundaries as pools of neural stem/progenitor cells regulated by Sox2. BMC Biol. 2016;14:57 pubmed 出版商
  • 免疫细胞化学; 人类; 1:2000; 图 2
Francis K, Ton A, Xin Y, O Halloran P, Wassif C, Malik N, et al. Modeling Smith-Lemli-Opitz syndrome with induced pluripotent stem cells reveals a causal role for Wnt/β-catenin defects in neuronal cholesterol synthesis phenotypes. Nat Med. 2016;22:388-96 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:100; 图 4b
Kovacs G, Szabo V, Pirity M. Absence of Rybp Compromises Neural Differentiation of Embryonic Stem Cells. Stem Cells Int. 2016;2016:4034620 pubmed 出版商
  • 免疫组化-石蜡切片; 鸡; 1:100; 图 3
  • 免疫组化; 鸡; 1:100; 图 3
  • 免疫印迹; 鸡; 1:1000; 图 5
Zhang S, Li Y, Tan R, Tsoi B, Huang W, Huang Y, et al. A new gestational diabetes mellitus model: hyperglycemia-induced eye malformation via inhibition of Pax6 in the chick embryo. Dis Model Mech. 2016;9:177-86 pubmed 出版商
  • 免疫细胞化学; 人类; 图 4
Choi J, Lee S, Mallard W, Clement K, Tagliazucchi G, Lim H, et al. A comparison of genetically matched cell lines reveals the equivalence of human iPSCs and ESCs. Nat Biotechnol. 2015;33:1173-81 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1
Werner A, Iwasaki S, McGourty C, Medina Ruiz S, Teerikorpi N, Fedrigo I, et al. Cell-fate determination by ubiquitin-dependent regulation of translation. Nature. 2015;525:523-7 pubmed 出版商
  • 免疫细胞化学; 人类; 1:5000
Ahn S, Kim T, Kim K, Chung S. Differentiation of human pluripotent stem cells into Medial Ganglionic Eminence vs. Caudal Ganglionic Eminence cells. Methods. 2016;101:103-12 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 s7e
Imai Y, Kobayashi Y, Inoshita T, Meng H, Arano T, Uemura K, et al. The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway. PLoS Genet. 2015;11:e1005503 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 s4
Parchem R, Moore N, Fish J, Parchem J, Braga T, Shenoy A, et al. miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability. Cell Rep. 2015;12:760-73 pubmed 出版商
  • 免疫细胞化学; 人类; 1:50
Ohlemacher S, Iglesias C, Sridhar A, Gamm D, Meyer J. Generation of highly enriched populations of optic vesicle-like retinal cells from human pluripotent stem cells. Curr Protoc Stem Cell Biol. 2015;32:1H.8.1-20 pubmed 出版商
  • 免疫细胞化学; 人类
Radonjić N, Memi F, Ortega J, Glidden N, Zhan H, Zecevic N. The Role of Sonic Hedgehog in the Specification of Human Cortical Progenitors In Vitro. Cereb Cortex. 2016;26:131-43 pubmed 出版商
  • 免疫组化; 鸡; 1:50
Fischer A, Zelinka C, Gallina D, Scott M, Todd L. Reactive microglia and macrophage facilitate the formation of Müller glia-derived retinal progenitors. Glia. 2014;62:1608-28 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:100
Akeju O, Davis Dusenbery B, Cassel S, Ichida J, Eggan K. Ketamine exposure in early development impairs specification of the primary germ cell layers. Neurotoxicol Teratol. 2014;43:59-68 pubmed 出版商
  • 免疫组化-冰冻切片; 鸡; 1:20
Lee K, Seo J, Shin J, Ji E, Roh J, Kim J, et al. Positive feedback loop between Sox2 and Sox6 inhibits neuronal differentiation in the developing central nervous system. Proc Natl Acad Sci U S A. 2014;111:2794-9 pubmed 出版商
  • 免疫组化-自由浮动切片; Spanish newt; 1:250
Joven A, Morona R, González A, Moreno N. Spatiotemporal patterns of Pax3, Pax6, and Pax7 expression in the developing brain of a urodele amphibian, Pleurodeles waltl. J Comp Neurol. 2013;521:3913-53 pubmed 出版商
  • 免疫组化; 鸡
Boije H, Ring H, Shirazi Fard S, Grundberg I, Nilsson M, Hallböök F. Alternative splicing of the chromodomain protein Morf4l1 pre-mRNA has implications on cell differentiation in the developing chicken retina. J Mol Neurosci. 2013;51:615-28 pubmed 出版商
  • 免疫组化; 鸡; 1:100
Liu C, Wang I, Wei F, Chien C. Neuronal intermediate filament ?-internexin is expressed by neuronal lineages in the developing chicken retina. Exp Eye Res. 2013;110:18-25 pubmed 出版商
  • 免疫组化-自由浮动切片; Spanish newt; 1:250
  • 免疫印迹; Spanish newt
  • 免疫印迹; 大鼠
Joven A, Morona R, González A, Moreno N. Expression patterns of Pax6 and Pax7 in the adult brain of a urodele amphibian, Pleurodeles waltl. J Comp Neurol. 2013;521:2088-124 pubmed 出版商
  • 免疫组化-石蜡切片; Gallot's lizard; 1:100
Romero Alemán M, Monzon Mayor M, Santos E, Lang D, Yanes C. Neuronal and glial differentiation during lizard (Gallotia galloti) visual system ontogeny. J Comp Neurol. 2012;520:2163-84 pubmed 出版商
  • 免疫组化; dime-store turtle; 1:500
Moreno N, Dominguez L, Morona R, González A. Subdivisions of the turtle Pseudemys scripta hypothalamus based on the expression of regulatory genes and neuronal markers. J Comp Neurol. 2012;520:453-78 pubmed 出版商
  • 免疫组化; 小鼠; 1:200
Bupesh M, Abellan A, Medina L. Genetic and experimental evidence supports the continuum of the central extended amygdala and a mutiple embryonic origin of its principal neurons. J Comp Neurol. 2011;519:3507-31 pubmed 出版商
  • 免疫组化-冰冻切片; dime-store turtle; 1:500
Moreno N, Morona R, Lopez J, González A. Subdivisions of the turtle Pseudemys scripta subpallium based on the expression of regulatory genes and neuronal markers. J Comp Neurol. 2010;518:4877-902 pubmed 出版商
  • 免疫组化-石蜡切片; lepidosaurs; 1:100
  • 免疫印迹; lepidosaurs; 1:100
Romero Alemán M, Monzon Mayor M, Santos E, Yanes C. Expression of neuronal markers, synaptic proteins, and glutamine synthetase in the control and regenerating lizard visual system. J Comp Neurol. 2010;518:4067-87 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:200
Tseng Y, Gruzdeva N, Li A, Chuang J, Sung C. Identification of the Tctex-1 regulatory element that directs expression to neural stem/progenitor cells in developing and adult brain. J Comp Neurol. 2010;518:3327-42 pubmed 出版商
  • 免疫细胞化学; 鸡; 1:100
Yan R, Liang L, Ma W, Li X, Xie W, Wang S. Neurogenin1 effectively reprograms cultured chick retinal pigment epithelial cells to differentiate toward photoreceptors. J Comp Neurol. 2010;518:526-46 pubmed 出版商
  • 免疫组化; 小鼠
Ivaniutsin U, Chen Y, Mason J, Price D, Pratt T. Adenomatous polyposis coli is required for early events in the normal growth and differentiation of the developing cerebral cortex. Neural Dev. 2009;4:3 pubmed 出版商
  • 免疫组化; 小鼠; 1:200
Elshatory Y, Deng M, Xie X, Gan L. Expression of the LIM-homeodomain protein Isl1 in the developing and mature mouse retina. J Comp Neurol. 2007;503:182-97 pubmed
  • 免疫组化-冰冻切片; 鸡; 1:50
Fischer A, Stanke J, Aloisio G, Hoy H, Stell W. Heterogeneity of horizontal cells in the chicken retina. J Comp Neurol. 2007;500:1154-71 pubmed
Campbell S, McDonald C, Krentz N, Lynn F, Hoffman B. TrxG Complex Catalytic and Non-catalytic Activity Play Distinct Roles in Pancreas Progenitor Specification and Differentiation. Cell Rep. 2019;28:1830-1844.e6 pubmed 出版商
He D, Guo R, Zheng D, Li P, Dong X, Gan L. Expression of Lhx6 in the adult and developing mouse retina. Gene Expr Patterns. 2019;34:119065 pubmed 出版商
Chacon J, Rogers C. Early expression of Tubulin Beta-III in avian cranial neural crest cells. Gene Expr Patterns. 2019;34:119067 pubmed 出版商
Lalioti M, Kaplani K, Lokka G, Georgomanolis T, Kyrousi C, Dong W, et al. GemC1 is a critical switch for neural stem cell generation in the postnatal brain. Glia. 2019;67:2360-2373 pubmed 出版商
Jean Charles N, Buenaventura D, Emerson M. Identification and characterization of early photoreceptor cis-regulatory elements and their relation to Onecut1. Neural Dev. 2018;13:26 pubmed 出版商
Luisier R, Tyzack G, Hall C, Mitchell J, Devine H, Taha D, et al. Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS. Nat Commun. 2018;9:2010 pubmed 出版商
Thawani A, Sirohi D, Kuhn R, Fekete D. Zika Virus Can Strongly Infect and Disrupt Secondary Organizers in the Ventricular Zone of the Embryonic Chicken Brain. Cell Rep. 2018;23:692-700 pubmed 出版商
Hsu F, Spannl S, Ferguson C, Hyman A, Parton R, Zerial M. Rab5 and Alsin regulate stress-activated cytoprotective signaling on mitochondria. elife. 2018;7: pubmed 出版商
Echeverri Ruiz N, Haynes T, Landers J, Woods J, Gemma M, Hughes M, et al. A biochemical basis for induction of retina regeneration by antioxidants. Dev Biol. 2018;433:394-403 pubmed 出版商
Gladwyn Ng I, Cordón Barris L, Alfano C, Creppe C, Couderc T, Morelli G, et al. Stress-induced unfolded protein response contributes to Zika virus-associated microcephaly. Nat Neurosci. 2018;21:63-71 pubmed 出版商
Marei H, Althani A, Lashen S, Cenciarelli C, Hasan A. Genetically unmatched human iPSC and ESC exhibit equivalent gene expression and neuronal differentiation potential. Sci Rep. 2017;7:17504 pubmed 出版商
Urbanska M, Winzi M, Neumann K, Abuhattum S, Rosendahl P, Müller P, et al. Single-cell mechanical phenotype is an intrinsic marker of reprogramming and differentiation along the mouse neural lineage. Development. 2017;144:4313-4321 pubmed 出版商
Lin B, Coleman J, Peterson J, Zunitch M, Jang W, Herrick D, et al. Injury Induces Endogenous Reprogramming and Dedifferentiation of Neuronal Progenitors to Multipotency. Cell Stem Cell. 2017;21:761-774.e5 pubmed 出版商
Nakagawa N, Li J, Yabuno Nakagawa K, Eom T, Cowles M, Mapp T, et al. APC sets the Wnt tone necessary for cerebral cortical progenitor development. Genes Dev. 2017;31:1679-1692 pubmed 出版商
Wang C, Li J, Meng Q, Wang B. Three Tctn proteins are functionally conserved in the regulation of neural tube patterning and Gli3 processing but not ciliogenesis and Hedgehog signaling in the mouse. Dev Biol. 2017;430:156-165 pubmed 出版商
Jossin Y, Lee M, Klezovitch O, Kon E, Cossard A, Lien W, et al. Llgl1 Connects Cell Polarity with Cell-Cell Adhesion in Embryonic Neural Stem Cells. Dev Cell. 2017;41:481-495.e5 pubmed 出版商
Moreno N, González A. Pattern of Neurogenesis and Identification of Neuronal Progenitor Subtypes during Pallial Development in Xenopus laevis. Front Neuroanat. 2017;11:24 pubmed 出版商
Terzenidou M, Segklia A, Kano T, Papastefanaki F, Karakostas A, Charalambous M, et al. Novel insights into SLC25A46-related pathologies in a genetic mouse model. PLoS Genet. 2017;13:e1006656 pubmed 出版商
Zhang Q, Zagozewski J, Cheng S, Dixit R, Zhang S, de Melo J, et al. Regulation of Brn3b by DLX1 and DLX2 is required for retinal ganglion cell differentiation in the vertebrate retina. Development. 2017;144:1698-1711 pubmed 出版商
Moshiri A, Humpal D, Leonard B, Imai D, Tham A, Bower L, et al. Arap1 Deficiency Causes Photoreceptor Degeneration in Mice. Invest Ophthalmol Vis Sci. 2017;58:1709-1718 pubmed 出版商
Hägglund A, Jones I, Carlsson L. A novel mouse model of anterior segment dysgenesis (ASD): conditional deletion of Tsc1 disrupts ciliary body and iris development. Dis Model Mech. 2017;10:245-257 pubmed 出版商
Boswell B, Korol A, West Mays J, Musil L. Dual function of TGF? in lens epithelial cell fate: implications for secondary cataract. Mol Biol Cell. 2017;28:907-921 pubmed 出版商
Subashini C, Dhanesh S, Chen C, Riya P, Meera V, Divya T, et al. Wnt5a is a crucial regulator of neurogenesis during cerebellum development. Sci Rep. 2017;7:42523 pubmed 出版商
Park K, Randazzo G, Jones K, Brzezinski J. Gsg1, Trnp1, and Tmem215 Mark Subpopulations of Bipolar Interneurons in the Mouse Retina. Invest Ophthalmol Vis Sci. 2017;58:1137-1150 pubmed 出版商
Yamashita T, Miyamoto Y, Bando Y, Ono T, Kobayashi S, Doi A, et al. Differentiation of oligodendrocyte progenitor cells from dissociated monolayer and feeder-free cultured pluripotent stem cells. PLoS ONE. 2017;12:e0171947 pubmed 出版商
Holmes D, Heine V. Simplified 3D protocol capable of generating early cortical neuroepithelium. Biol Open. 2017;6:402-406 pubmed 出版商
Dyson J, Conduit S, Feeney S, Hakim S, DiTommaso T, Fulcher A, et al. INPP5E regulates phosphoinositide-dependent cilia transition zone function. J Cell Biol. 2017;216:247-263 pubmed 出版商
Wefers A, Lindner S, Schulte J, Schüller U. Overexpression of Lin28b in Neural Stem Cells is Insufficient for Brain Tumor Formation, but Induces Pathological Lobulation of the Developing Cerebellum. Cerebellum. 2017;16:122-131 pubmed 出版商
Francius C, Hidalgo Figueroa M, Debrulle S, Pelosi B, Rucchin V, Ronellenfitch K, et al. Vsx1 Transiently Defines an Early Intermediate V2 Interneuron Precursor Compartment in the Mouse Developing Spinal Cord. Front Mol Neurosci. 2016;9:145 pubmed 出版商
Luchetti G, Sircar R, Kong J, Nachtergaele S, Sagner A, Byrne E, et al. Cholesterol activates the G-protein coupled receptor Smoothened to promote Hedgehog signaling. elife. 2016;5: pubmed 出版商
Pei S, Liu L, Zhong Z, Wang H, Lin S, Shang J. Risk of prenatal depression and stress treatment: alteration on serotonin system of offspring through exposure to Fluoxetine. Sci Rep. 2016;6:33822 pubmed 出版商
de Melo J, Clark B, Blackshaw S. Multiple intrinsic factors act in concert with Lhx2 to direct retinal gliogenesis. Sci Rep. 2016;6:32757 pubmed 出版商
Abdullah A, Zhang H, Nie Y, Tang W, Sun T. CDK7 and miR-210 Co-regulate Cell-Cycle Progression of Neural Progenitors in the Developing Neocortex. Stem Cell Reports. 2016;7:69-79 pubmed 出版商
Tonchev A, Tuoc T, Rosenthal E, Studer M, Stoykova A. Zbtb20 modulates the sequential generation of neuronal layers in developing cortex. Mol Brain. 2016;9:65 pubmed 出版商
Demers C, Soundararajan P, Chennampally P, Cox G, Briscoe J, Collins S, et al. Development-on-chip: in vitro neural tube patterning with a microfluidic device. Development. 2016;143:1884-92 pubmed 出版商
Dorà N, Crookshanks A, Leung K, Simpson T, Mason J, Price D, et al. Analysis of compound heterozygotes reveals that the mouse floxed Pax6 (tm1Ued) allele produces abnormal eye phenotypes. Transgenic Res. 2016;25:679-92 pubmed 出版商
Suiko T, Kobayashi K, Aono K, Kawashima T, Inoue K, Ku L, et al. Expression of Quaking RNA-Binding Protein in the Adult and Developing Mouse Retina. PLoS ONE. 2016;11:e0156033 pubmed 出版商
PACKARD A, Lin B, Schwob J. Sox2 and Pax6 Play Counteracting Roles in Regulating Neurogenesis within the Murine Olfactory Epithelium. PLoS ONE. 2016;11:e0155167 pubmed 出版商
Feng J, Xian Q, Guan T, Hu J, Wang M, Huang Y, et al. Celsr3 and Fzd3 Organize a Pioneer Neuron Scaffold to Steer Growing Thalamocortical Axons. Cereb Cortex. 2016;26:3323-34 pubmed 出版商
De Filippis L, Halikere A, McGowan H, Moore J, Tischfield J, Hart R, et al. Ethanol-mediated activation of the NLRP3 inflammasome in iPS cells and iPS cells-derived neural progenitor cells. Mol Brain. 2016;9:51 pubmed 出版商
Cai X, Kardon A, Snyder L, Kuzirian M, Minestro S, de Souza L, et al. Bhlhb5::flpo allele uncovers a requirement for Bhlhb5 for the development of the dorsal cochlear nucleus. Dev Biol. 2016;414:149-60 pubmed 出版商
Kadoya K, Lu P, Nguyen K, Lee Kubli C, Kumamaru H, Yao L, et al. Spinal cord reconstitution with homologous neural grafts enables robust corticospinal regeneration. Nat Med. 2016;22:479-87 pubmed 出版商
Gabriel E, Wason A, Ramani A, Gooi L, Keller P, Pozniakovsky A, et al. CPAP promotes timely cilium disassembly to maintain neural progenitor pool. EMBO J. 2016;35:803-19 pubmed 出版商
de Melo J, Zibetti C, Clark B, Hwang W, Miranda Angulo A, Qian J, et al. Lhx2 Is an Essential Factor for Retinal Gliogenesis and Notch Signaling. J Neurosci. 2016;36:2391-405 pubmed 出版商
Bhattacharyya S, Rainey M, Arya P, Mohapatra B, Mushtaq I, Dutta S, et al. Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development. Sci Rep. 2016;6:20727 pubmed 出版商
Wang Y, Wu Q, Yang P, Wang C, Liu J, Ding W, et al. LSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brain. Nat Commun. 2016;7:10481 pubmed 出版商
Rahimi Balaei M, Jiao X, Ashtari N, Afsharinezhad P, Ghavami S, Marzban H. Cerebellar Expression of the Neurotrophin Receptor p75 in Naked-Ataxia Mutant Mouse. Int J Mol Sci. 2016;17: pubmed 出版商
Wymeersch F, Huang Y, Blin G, Cambray N, Wilkie R, Wong F, et al. Position-dependent plasticity of distinct progenitor types in the primitive streak. elife. 2016;5:e10042 pubmed 出版商
Nomura T, Ohtaka Maruyama C, Yamashita W, Wakamatsu Y, Murakami Y, Calegari F, et al. The evolution of basal progenitors in the developing non-mammalian brain. Development. 2016;143:66-74 pubmed 出版商
Zemke M, Draganova K, Klug A, Schöler A, Zurkirchen L, Gay M, et al. Loss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulation. BMC Biol. 2015;13:103 pubmed 出版商
Clegg J, Li Z, Molinek M, Caballero I, Manuel M, Price D. Pax6 is required intrinsically by thalamic progenitors for the normal molecular patterning of thalamic neurons but not the growth and guidance of their axons. Neural Dev. 2015;10:26 pubmed 出版商
Jones I, Hägglund A, Törnqvist G, Nord C, Ahlgren U, Carlsson L. A novel mouse model of tuberous sclerosis complex (TSC): eye-specific Tsc1-ablation disrupts visual-pathway development. Dis Model Mech. 2015;8:1517-29 pubmed 出版商
Straccia M, Garcia Díaz Barriga G, Sanders P, Bombau G, Carrere J, Mairal P, et al. Quantitative high-throughput gene expression profiling of human striatal development to screen stem cell-derived medium spiny neurons. Mol Ther Methods Clin Dev. 2015;2:15030 pubmed 出版商
Yao H, Gao M, Ma J, Zhang M, Li S, Wu B, et al. Transdifferentiation-Induced Neural Stem Cells Promote Recovery of Middle Cerebral Artery Stroke Rats. PLoS ONE. 2015;10:e0137211 pubmed 出版商
Oh S, Kato M, Zhang C, Guo Y, Beachy P. A Comparison of Ci/Gli Activity as Regulated by Sufu in Drosophila and Mammalian Hedgehog Response. PLoS ONE. 2015;10:e0135804 pubmed 出版商
Todd L, Suarez L, Squires N, Zelinka C, Gribbins K, Fischer A. Comparative analysis of glucagonergic cells, glia, and the circumferential marginal zone in the reptilian retina. J Comp Neurol. 2016;524:74-89 pubmed 出版商
Nomura T, Yamashita W, Gotoh H, Ono K. Genetic manipulation of reptilian embryos: toward an understanding of cortical development and evolution. Front Neurosci. 2015;9:45 pubmed 出版商
Martinez Lopez J, Moreno Bravo J, Madrigal M, Martinez S, Puelles E. Mesencephalic basolateral domain specification is dependent on Sonic Hedgehog. Front Neuroanat. 2015;9:12 pubmed 出版商
Yan R, He L, Zhan W, Wang S. Induction of ectopic retina-like tissue by transgenic expression of neurogenin. PLoS ONE. 2015;10:e0116171 pubmed 出版商
López Escobar B, Cano D, Rojas A, De Felipe B, Palma F, Sánchez Alcázar J, et al. The effect of maternal diabetes on the Wnt-PCP pathway during embryogenesis as reflected in the developing mouse eye. Dis Model Mech. 2015;8:157-68 pubmed 出版商
Patterson V, Zullo A, Koenig C, Stoessel S, Jo H, Liu X, et al. Neural-specific deletion of Htra2 causes cerebellar neurodegeneration and defective processing of mitochondrial OPA1. PLoS ONE. 2014;9:e115789 pubmed 出版商
Kindberg A, Bendriem R, Spivak C, Chen J, Handreck A, Lupica C, et al. An in vitro model of human neocortical development using pluripotent stem cells: cocaine-induced cytoarchitectural alterations. Dis Model Mech. 2014;7:1397-405 pubmed 出版商
Insolera R, Bazzi H, Shao W, Anderson K, Shi S. Cortical neurogenesis in the absence of centrioles. Nat Neurosci. 2014;17:1528-35 pubmed 出版商
Dorà N, Collinson J, Hill R, West J. Hemizygous Le-Cre transgenic mice have severe eye abnormalities on some genetic backgrounds in the absence of LoxP sites. PLoS ONE. 2014;9:e109193 pubmed 出版商
He X, Zhang L, Chen Y, Remke M, Shih D, Lu F, et al. The G protein α subunit Gαs is a tumor suppressor in Sonic hedgehog-driven medulloblastoma. Nat Med. 2014;20:1035-42 pubmed 出版商
Moreno N, Joven A, Morona R, Bandín S, López J, González A. Conserved localization of Pax6 and Pax7 transcripts in the brain of representatives of sarcopterygian vertebrates during development supports homologous brain regionalization. Front Neuroanat. 2014;8:75 pubmed 出版商
Cardozo M, Sánchez Arrones L, Sandonìs A, Sánchez Camacho C, Gestri G, Wilson S, et al. Cdon acts as a Hedgehog decoy receptor during proximal-distal patterning of the optic vesicle. Nat Commun. 2014;5:4272 pubmed 出版商
Meier F, Giesert F, Delic S, Faus Kessler T, Matheus F, Simeone A, et al. FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum. PLoS ONE. 2014;9:e101124 pubmed 出版商
Bandín S, Morona R, Lopez J, Moreno N, González A. Immunohistochemical analysis of Pax6 and Pax7 expression in the CNS of adult Xenopus laevis. J Chem Neuroanat. 2014;57-58:24-41 pubmed 出版商
Bazzi H, Anderson K. Acentriolar mitosis activates a p53-dependent apoptosis pathway in the mouse embryo. Proc Natl Acad Sci U S A. 2014;111:E1491-500 pubmed 出版商
Ma Z, Wang G, Cheng X, Chuai M, Kurihara H, Lee K, et al. Excess caffeine exposure impairs eye development during chick embryogenesis. J Cell Mol Med. 2014;18:1134-43 pubmed 出版商
Sarode B, Nowell C, Ihm J, Kostic C, Arsenijevic Y, Moulin A, et al. Notch signaling in the pigmented epithelium of the anterior eye segment promotes ciliary body development at the expense of iris formation. Pigment Cell Melanoma Res. 2014;27:580-9 pubmed 出版商
Toriyama A, Mori T, Sekine S, Yoshida A, Hino O, Tsuta K. Utility of PAX8 mouse monoclonal antibody in the diagnosis of thyroid, thymic, pleural and lung tumours: a comparison with polyclonal PAX8 antibody. Histopathology. 2014;65:465-72 pubmed 出版商
Chatterjee M, Guo Q, Weber S, Scholpp S, LI J. Pax6 regulates the formation of the habenular nuclei by controlling the temporospatial expression of Shh in the diencephalon in vertebrates. BMC Biol. 2014;12:13 pubmed 出版商
Mikhailova A, Ilmarinen T, Uusitalo H, Skottman H. Small-molecule induction promotes corneal epithelial cell differentiation from human induced pluripotent stem cells. Stem Cell Reports. 2014;2:219-31 pubmed 出版商
Kim B, Scott D. Mouse model reveals the role of RERE in cerebellar foliation and the migration and maturation of Purkinje cells. PLoS ONE. 2014;9:e87518 pubmed 出版商
Hui S, Sengupta D, Lee S, Sen T, Kundu S, Mathavan S, et al. Genome wide expression profiling during spinal cord regeneration identifies comprehensive cellular responses in zebrafish. PLoS ONE. 2014;9:e84212 pubmed 出版商
Li Y, Hao H, Tzatzalos E, Lin R, Doh S, Liu L, et al. Topoisomerase IIbeta is required for proper retinal development and survival of postmitotic cells. Biol Open. 2014;3:172-84 pubmed 出版商
Huang K, Liu P, Li X, Chen S, Wang L, Qin L, et al. Neural progenitor cells from human induced pluripotent stem cells generated less autogenous immune response. Sci China Life Sci. 2014;57:162-70 pubmed 出版商
Yan X, Lin J, Talabattula V, Mußmann C, Yang F, Wree A, et al. ADAM10 negatively regulates neuronal differentiation during spinal cord development. PLoS ONE. 2014;9:e84617 pubmed 出版商
Alves C, Bossers K, Vos R, Essing A, Swagemakers S, van der Spek P, et al. Microarray and morphological analysis of early postnatal CRB2 mutant retinas on a pure C57BL/6J genetic background. PLoS ONE. 2013;8:e82532 pubmed 出版商
Wang J, Park J, Drissi H, Wang X, Xu R. Epigenetic regulation of miR-302 by JMJD1C inhibits neural differentiation of human embryonic stem cells. J Biol Chem. 2014;289:2384-95 pubmed 出版商
Cui C, Chatterjee B, Lozito T, Zhang Z, Francis R, Yagi H, et al. Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton. PLoS Biol. 2013;11:e1001720 pubmed 出版商
Bhatia S, Bengani H, Fish M, Brown A, Divizia M, De Marco R, et al. Disruption of autoregulatory feedback by a mutation in a remote, ultraconserved PAX6 enhancer causes aniridia. Am J Hum Genet. 2013;93:1126-34 pubmed 出版商
Nguyen H, Ostendorf A, Satz J, Westra S, Ross Barta S, Campbell K, et al. Glial scaffold required for cerebellar granule cell migration is dependent on dystroglycan function as a receptor for basement membrane proteins. Acta Neuropathol Commun. 2013;1:58 pubmed 出版商
Tabrizi G, Böse K, Reimann Y, Kessel M. Geminin is required for the maintenance of pluripotency. PLoS ONE. 2013;8:e73826 pubmed 出版商
Knauss J, Bian S, Sun T. Plasmid-based target protectors allow specific blockade of miRNA silencing activity in mammalian developmental systems. Front Cell Neurosci. 2013;7:163 pubmed 出版商
Colasante G, Simonet J, Calogero R, Crispi S, Sessa A, Cho G, et al. ARX regulates cortical intermediate progenitor cell expansion and upper layer neuron formation through repression of Cdkn1c. Cereb Cortex. 2015;25:322-35 pubmed 出版商
Francius C, Harris A, Rucchin V, Hendricks T, Stam F, Barber M, et al. Identification of multiple subsets of ventral interneurons and differential distribution along the rostrocaudal axis of the developing spinal cord. PLoS ONE. 2013;8:e70325 pubmed 出版商
Li C, Ito H, Fujita K, Shiwaku H, Qi Y, Tagawa K, et al. Sox2 transcriptionally regulates PQBP1, an intellectual disability-microcephaly causative gene, in neural stem progenitor cells. PLoS ONE. 2013;8:e68627 pubmed 出版商
Pilz G, Shitamukai A, Reillo I, Pacary E, Schwausch J, Stahl R, et al. Amplification of progenitors in the mammalian telencephalon includes a new radial glial cell type. Nat Commun. 2013;4:2125 pubmed 出版商
Zhang L, Wahlin K, Li Y, Masuda T, Yang Z, Zack D, et al. RIT2, a neuron-specific small guanosine triphosphatase, is expressed in retinal neuronal cells and its promoter is modulated by the POU4 transcription factors. Mol Vis. 2013;19:1371-86 pubmed
Hou P, Chuang C, Kao C, Chou S, Stone L, Ho H, et al. LHX2 regulates the neural differentiation of human embryonic stem cells via transcriptional modulation of PAX6 and CER1. Nucleic Acids Res. 2013;41:7753-70 pubmed 出版商
Taylor Weiner H, Schwarzbauer J, Engler A. Defined extracellular matrix components are necessary for definitive endoderm induction. Stem Cells. 2013;31:2084-94 pubmed 出版商
Jha R, Chrenek R, Magnotti L, Cardozo D. The isolation, differentiation, and survival in vivo of multipotent cells from the postnatal rat filum terminale. PLoS ONE. 2013;8:e65974 pubmed 出版商
Cunningham C, Martinez Cerdeno V, Noctor S. Diversity of neural precursor cell types in the prenatal macaque cerebral cortex exists largely within the astroglial cell lineage. PLoS ONE. 2013;8:e63848 pubmed 出版商
Liu N, Wang M, Deng W, Schmidt C, Qin W, Leonhardt H, et al. Intrinsic and extrinsic connections of Tet3 dioxygenase with CXXC zinc finger modules. PLoS ONE. 2013;8:e62755 pubmed 出版商
Fotaki V, Smith R, Pratt T, Price D. Foxg1 is required to limit the formation of ciliary margin tissue and Wnt/?-catenin signalling in the developing nasal retina of the mouse. Dev Biol. 2013;380:299-313 pubmed 出版商
Mi D, Carr C, Georgala P, Huang Y, Manuel M, Jeanes E, et al. Pax6 exerts regional control of cortical progenitor proliferation via direct repression of Cdk6 and hypophosphorylation of pRb. Neuron. 2013;78:269-84 pubmed 出版商
Tang M, Luo S, Tang V, Huang E. Temporal and spatial requirements of Smoothened in ventral midbrain neuronal development. Neural Dev. 2013;8:8 pubmed 出版商
Mazur M, Winkler M, Ganic E, Colberg J, Johansson J, Bennet H, et al. Microphthalmia transcription factor regulates pancreatic β-cell function. Diabetes. 2013;62:2834-42 pubmed 出版商
Betschinger J, Nichols J, Dietmann S, Corrin P, Paddison P, Smith A. Exit from pluripotency is gated by intracellular redistribution of the bHLH transcription factor Tfe3. Cell. 2013;153:335-47 pubmed 出版商
Tian C, Liu Q, Ma K, Wang Y, Chen Q, Ambroz R, et al. Characterization of induced neural progenitors from skin fibroblasts by a novel combination of defined factors. Sci Rep. 2013;3:1345 pubmed 出版商
Kim K, Nam J, Mukouyama Y, Kawamoto S. Rbfox3-regulated alternative splicing of Numb promotes neuronal differentiation during development. J Cell Biol. 2013;200:443-58 pubmed 出版商
Alsiö J, Tarchini B, Cayouette M, Livesey F. Ikaros promotes early-born neuronal fates in the cerebral cortex. Proc Natl Acad Sci U S A. 2013;110:E716-25 pubmed 出版商
Imamura F, Greer C. Pax6 regulates Tbr1 and Tbr2 expressions in olfactory bulb mitral cells. Mol Cell Neurosci. 2013;54:58-70 pubmed 出版商
Watanabe S, Sanuki R, Ueno S, Koyasu T, Hasegawa T, Furukawa T. Tropisms of AAV for subretinal delivery to the neonatal mouse retina and its application for in vivo rescue of developmental photoreceptor disorders. PLoS ONE. 2013;8:e54146 pubmed 出版商
Lee K, Zhou W, Scott McKean J, Emmerling K, Cai G, Krah D, et al. Human sensory neurons derived from induced pluripotent stem cells support varicella-zoster virus infection. PLoS ONE. 2012;7:e53010 pubmed 出版商
Chen S, Lewis B, Moran A, Xie T. Cadherin-mediated cell adhesion is critical for the closing of the mouse optic fissure. PLoS ONE. 2012;7:e51705 pubmed 出版商
Rabe T, Griesel G, Blanke S, Kispert A, Leitges M, van der Zwaag B, et al. The transcription factor Uncx4.1 acts in a short window of midbrain dopaminergic neuron differentiation. Neural Dev. 2012;7:39 pubmed 出版商
Ballios B, Clarke L, Coles B, Shoichet M, van der Kooy D. The adult retinal stem cell is a rare cell in the ciliary epithelium whose progeny can differentiate into photoreceptors. Biol Open. 2012;1:237-46 pubmed 出版商
Norris F, Betts Henderson J, Wells J, Cleary J, Siow B, Walker Samuel S, et al. Enhanced tissue differentiation in the developing mouse brain using magnetic resonance micro-histology. Magn Reson Med. 2013;70:1380-8 pubmed 出版商
Paul V, Tonchev A, Henningfeld K, Pavlakis E, Rust B, Pieler T, et al. Scratch2 modulates neurogenesis and cell migration through antagonism of bHLH proteins in the developing neocortex. Cereb Cortex. 2014;24:754-72 pubmed 出版商
Law K, Makino S, Mo R, Zhang X, Puviindran V, Hui C. Antagonistic and cooperative actions of Kif7 and Sufu define graded intracellular Gli activities in Hedgehog signaling. PLoS ONE. 2012;7:e50193 pubmed 出版商
Piotrowska Nitsche K, Caspary T. Live imaging of individual cell divisions in mouse neuroepithelium shows asymmetry in cilium formation and Sonic hedgehog response. Cilia. 2012;1: pubmed 出版商
Nishihara D, Yajima I, Tabata H, Nakai M, Tsukiji N, Katahira T, et al. Otx2 is involved in the regional specification of the developing retinal pigment epithelium by preventing the expression of sox2 and fgf8, factors that induce neural retina differentiation. PLoS ONE. 2012;7:e48879 pubmed 出版商
Watanabe M, Kang Y, Davies L, Meghpara S, Lau K, Chung C, et al. BMP4 sufficiency to induce choroid plexus epithelial fate from embryonic stem cell-derived neuroepithelial progenitors. J Neurosci. 2012;32:15934-45 pubmed 出版商
Wang Q, Yang L, Alexander C, Temple S. The niche factor syndecan-1 regulates the maintenance and proliferation of neural progenitor cells during mammalian cortical development. PLoS ONE. 2012;7:e42883 pubmed 出版商
Lin F, Chui Y. Generation of induced pluripotent stem cells from mouse cancer cells. Cancer Biother Radiopharm. 2012;27:694-700 pubmed 出版商
Czekaj M, Haas J, Gebhardt M, MULLER REICHERT T, Humphries P, Farrar J, et al. In vitro expanded stem cells from the developing retina fail to generate photoreceptors but differentiate into myelinating oligodendrocytes. PLoS ONE. 2012;7:e41798 pubmed 出版商
Lüningschrör P, Kaltschmidt B, Kaltschmidt C. Knockdown of IKK1/2 promotes differentiation of mouse embryonic stem cells into neuroectoderm at the expense of mesoderm. Stem Cell Rev. 2012;8:1098-108 pubmed 出版商
Rostovskaya M, Fu J, Obst M, Baer I, Weidlich S, Wang H, et al. Transposon-mediated BAC transgenesis in human ES cells. Nucleic Acids Res. 2012;40:e150 pubmed 出版商
Chambers S, Qi Y, Mica Y, Lee G, Zhang X, Niu L, et al. Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors. Nat Biotechnol. 2012;30:715-20 pubmed 出版商
Bluske K, Vue T, Kawakami Y, Taketo M, Yoshikawa K, Johnson J, et al. ?-Catenin signaling specifies progenitor cell identity in parallel with Shh signaling in the developing mammalian thalamus. Development. 2012;139:2692-702 pubmed 出版商
Garcia Calero E, Scharff C. Calbindin expression in developing striatum of zebra finches and its relation to the formation of area X. J Comp Neurol. 2013;521:326-41 pubmed 出版商
Kordowich S, Serup P, Collombat P, Mansouri A. Generation of animals allowing the conditional inactivation of the Pax4 gene. Transgenic Res. 2012;21:1215-20 pubmed 出版商
Ring H, Mendu S, Shirazi Fard S, Birnir B, Hallböök F. GABA maintains the proliferation of progenitors in the developing chick ciliary marginal zone and non-pigmented ciliary epithelium. PLoS ONE. 2012;7:e36874 pubmed 出版商
Liu R, Monckton E, Godbout R. Regulation of the FABP7 gene by PAX6 in malignant glioma cells. Biochem Biophys Res Commun. 2012;422:482-7 pubmed 出版商
Mak S, Huang Y, Iranmanesh S, Vangipuram M, Sundararajan R, Nguyen L, et al. Small molecules greatly improve conversion of human-induced pluripotent stem cells to the neuronal lineage. Stem Cells Int. 2012;2012:140427 pubmed 出版商
Han L, Pan Y, Wang B. Small ubiquitin-like Modifier (SUMO) modification inhibits GLI2 protein transcriptional activity in vitro and in vivo. J Biol Chem. 2012;287:20483-9 pubmed 出版商
Cheng F, Huang X, Sarangi A, Ketova T, Cooper M, Litingtung Y, et al. Widespread contribution of Gdf7 lineage to cerebellar cell types and implications for hedgehog-driven medulloblastoma formation. PLoS ONE. 2012;7:e35541 pubmed 出版商
Kerr C, Huang J, Williams T, West Mays J. Activation of the hedgehog signaling pathway in the developing lens stimulates ectopic FoxE3 expression and disruption in fiber cell differentiation. Invest Ophthalmol Vis Sci. 2012;53:3316-30 pubmed 出版商
Denham M, Parish C, Leaw B, Wright J, Reid C, Petrou S, et al. Neurons derived from human embryonic stem cells extend long-distance axonal projections through growth along host white matter tracts after intra-cerebral transplantation. Front Cell Neurosci. 2012;6:11 pubmed 出版商
Chen Y, Magnani D, Theil T, Pratt T, Price D. Evidence that descending cortical axons are essential for thalamocortical axons to cross the pallial-subpallial boundary in the embryonic forebrain. PLoS ONE. 2012;7:e33105 pubmed 出版商
Bultmann S, Morbitzer R, Schmidt C, Thanisch K, Spada F, Elsaesser J, et al. Targeted transcriptional activation of silent oct4 pluripotency gene by combining designer TALEs and inhibition of epigenetic modifiers. Nucleic Acids Res. 2012;40:5368-77 pubmed 出版商
Todd K, Lan Chow Wing N, Salin Cantegrel A, Cotter A, Zagami C, Lo R, et al. Establishment of motor neuron-V3 interneuron progenitor domain boundary in ventral spinal cord requires Groucho-mediated transcriptional corepression. PLoS ONE. 2012;7:e31176 pubmed 出版商
Joksimovic M, Patel M, Taketo M, Johnson R, Awatramani R. Ectopic Wnt/beta-catenin signaling induces neurogenesis in the spinal cord and hindbrain floor plate. PLoS ONE. 2012;7:e30266 pubmed 出版商
Martinez Cerdeno V, Cunningham C, Camacho J, Antczak J, Prakash A, Cziep M, et al. Comparative analysis of the subventricular zone in rat, ferret and macaque: evidence for an outer subventricular zone in rodents. PLoS ONE. 2012;7:e30178 pubmed 出版商
Lüningschrör P, Stöcker B, Kaltschmidt B, Kaltschmidt C. miR-290 cluster modulates pluripotency by repressing canonical NF-?B signaling. Stem Cells. 2012;30:655-64 pubmed 出版商
Jang J, Yoo J, Lee J, Lee D, Kim J, Huh Y, et al. Disease-specific induced pluripotent stem cells: a platform for human disease modeling and drug discovery. Exp Mol Med. 2012;44:202-13 pubmed 出版商
McUsic A, Lamba D, Reh T. Guiding the morphogenesis of dissociated newborn mouse retinal cells and hES cell-derived retinal cells by soft lithography-patterned microchannel PLGA scaffolds. Biomaterials. 2012;33:1396-405 pubmed 出版商
Kunisada Y, Tsubooka Yamazoe N, Shoji M, Hosoya M. Small molecules induce efficient differentiation into insulin-producing cells from human induced pluripotent stem cells. Stem Cell Res. 2012;8:274-84 pubmed 出版商
Zhang H, Deo M, Thompson R, Uhler M, Turner D. Negative regulation of Yap during neuronal differentiation. Dev Biol. 2012;361:103-15 pubmed 出版商
Di Lullo E, Haton C, Le Poupon C, Volovitch M, Joliot A, Thomas J, et al. Paracrine Pax6 activity regulates oligodendrocyte precursor cell migration in the chick embryonic neural tube. Development. 2011;138:4991-5001 pubmed 出版商
Yoo Y, Huang C, Zhang X, LaVaute T, Zhang S. Fibroblast growth factor regulates human neuroectoderm specification through ERK1/2-PARP-1 pathway. Stem Cells. 2011;29:1975-82 pubmed 出版商
Ananiev G, Williams E, Li H, Chang Q. Isogenic pairs of wild type and mutant induced pluripotent stem cell (iPSC) lines from Rett syndrome patients as in vitro disease model. PLoS ONE. 2011;6:e25255 pubmed 出版商
Lorenzo P, Jimenez Moreno C, Delgado I, Cobo Vuilleumier N, Meier R, Gómez Izquierdo L, et al. Immunohistochemical assessment of Pax8 expression during pancreatic islet development and in human neuroendocrine tumors. Histochem Cell Biol. 2011;136:595-607 pubmed 出版商
Nowakowski T, Mysiak K, Pratt T, Price D. Functional dicer is necessary for appropriate specification of radial glia during early development of mouse telencephalon. PLoS ONE. 2011;6:e23013 pubmed 出版商
Kay J, Voinescu P, Chu M, Sanes J. Neurod6 expression defines new retinal amacrine cell subtypes and regulates their fate. Nat Neurosci. 2011;14:965-72 pubmed 出版商
MacArthur C, Xue H, Van Hoof D, Lieu P, Dudas M, Fontes A, et al. Chromatin insulator elements block transgene silencing in engineered human embryonic stem cell lines at a defined chromosome 13 locus. Stem Cells Dev. 2012;21:191-205 pubmed 出版商
Spella M, Kyrousi C, Kritikou E, Stathopoulou A, Guillemot F, Kioussis D, et al. Geminin regulates cortical progenitor proliferation and differentiation. Stem Cells. 2011;29:1269-82 pubmed 出版商
Erskine L, Reijntjes S, Pratt T, Denti L, Schwarz Q, Vieira J, et al. VEGF signaling through neuropilin 1 guides commissural axon crossing at the optic chiasm. Neuron. 2011;70:951-65 pubmed 出版商
Fung H, Weinstock D. Repair at single targeted DNA double-strand breaks in pluripotent and differentiated human cells. PLoS ONE. 2011;6:e20514 pubmed 出版商
Szabó N, Zhao T, Cankaya M, Stoykova A, Zhou X, Alvarez Bolado G. Interaction between axons and specific populations of surrounding cells is indispensable for collateral formation in the mammillary system. PLoS ONE. 2011;6:e20315 pubmed 出版商
Cai Z, Simons D, Fu X, Feng G, Wu S, Zhang X. Loss of Shp2-mediated mitogen-activated protein kinase signaling in Muller glial cells results in retinal degeneration. Mol Cell Biol. 2011;31:2973-83 pubmed 出版商
de Melo J, Peng G, Chen S, Blackshaw S. The Spalt family transcription factor Sall3 regulates the development of cone photoreceptors and retinal horizontal interneurons. Development. 2011;138:2325-36 pubmed 出版商
Kubota Y, Takubo K, Hirashima M, Nagoshi N, Kishi K, Okuno Y, et al. Isolation and function of mouse tissue resident vascular precursors marked by myelin protein zero. J Exp Med. 2011;208:949-60 pubmed 出版商
Jossin Y, Cooper J. Reelin, Rap1 and N-cadherin orient the migration of multipolar neurons in the developing neocortex. Nat Neurosci. 2011;14:697-703 pubmed 出版商
Holmberg J, He X, Peredo I, Orrego A, Hesselager G, Ericsson C, et al. Activation of neural and pluripotent stem cell signatures correlates with increased malignancy in human glioma. PLoS ONE. 2011;6:e18454 pubmed 出版商
Ishizuka K, Kamiya A, Oh E, Kanki H, Seshadri S, Robinson J, et al. DISC1-dependent switch from progenitor proliferation to migration in the developing cortex. Nature. 2011;473:92-6 pubmed 出版商
Manuel M, Martynoga B, Molinek M, Quinn J, Kroemmer C, Mason J, et al. The transcription factor Foxg1 regulates telencephalic progenitor proliferation cell autonomously, in part by controlling Pax6 expression levels. Neural Dev. 2011;6:9 pubmed 出版商
Patani R, Hollins A, Wishart T, Puddifoot C, Alvarez S, de Lera A, et al. Retinoid-independent motor neurogenesis from human embryonic stem cells reveals a medial columnar ground state. Nat Commun. 2011;2:214 pubmed 出版商
Prasadan K, Koizumi M, Tulachan S, Shiota C, Lath N, Paredes J, et al. The expression and function of glucose-dependent insulinotropic polypeptide in the embryonic mouse pancreas. Diabetes. 2011;60:548-54 pubmed 出版商
Carbe C, Zhang X. Lens induction requires attenuation of ERK signaling by Nf1. Hum Mol Genet. 2011;20:1315-23 pubmed 出版商
Blazquez Llorca L, Garcia Marin V, DeFelipe J. GABAergic complex basket formations in the human neocortex. J Comp Neurol. 2010;518:4917-37 pubmed 出版商
Duquette P, Zhou X, Yap N, MacLaren E, Lu J, Wallace V, et al. Loss of LMO4 in the retina leads to reduction of GABAergic amacrine cells and functional deficits. PLoS ONE. 2010;5:e13232 pubmed 出版商
Wolf G, Hessabi B, Karkour A, Henrion U, Dahlhaus M, Ostmann A, et al. The activation of the rat insulin gene II by BETA2 and PDX-1 in rat insulinoma cells is repressed by Pax6. Mol Endocrinol. 2010;24:2331-42 pubmed 出版商
Lin H, Bell E, Uwanogho D, Perfect L, Noristani H, Bates T, et al. Neuronatin promotes neural lineage in ESCs via Ca(2+) signaling. Stem Cells. 2010;28:1950-60 pubmed 出版商
Miyata T, Ono Y, Okamoto M, Masaoka M, Sakakibara A, Kawaguchi A, et al. Migration, early axonogenesis, and Reelin-dependent layer-forming behavior of early/posterior-born Purkinje cells in the developing mouse lateral cerebellum. Neural Dev. 2010;5:23 pubmed 出版商
Leung H, Chen A, Choo A, Reuveny S, Oh S. Agitation can induce differentiation of human pluripotent stem cells in microcarrier cultures. Tissue Eng Part C Methods. 2011;17:165-72 pubmed 出版商
Artner I, Hang Y, Mazur M, Yamamoto T, Guo M, Lindner J, et al. MafA and MafB regulate genes critical to beta-cells in a unique temporal manner. Diabetes. 2010;59:2530-9 pubmed 出版商
Stanke J, Moose H, El Hodiri H, Fischer A. Comparative study of Pax2 expression in glial cells in the retina and optic nerve of birds and mammals. J Comp Neurol. 2010;518:2316-33 pubmed 出版商
Peltopuro P, Kala K, Partanen J. Distinct requirements for Ascl1 in subpopulations of midbrain GABAergic neurons. Dev Biol. 2010;343:63-70 pubmed 出版商
Suter D, Preynat Seauve O, Tirefort D, Feki A, Krause K. Phenazopyridine induces and synchronizes neuronal differentiation of embryonic stem cells. J Cell Mol Med. 2009;13:3517-27 pubmed 出版商
Quinn J, Molinek M, Nowakowski T, Mason J, Price D. Novel lines of Pax6-/- embryonic stem cells exhibit reduced neurogenic capacity without loss of viability. BMC Neurosci. 2010;11:26 pubmed 出版商
Shen J, Gilmore E, Marshall C, Haddadin M, Reynolds J, Eyaid W, et al. Mutations in PNKP cause microcephaly, seizures and defects in DNA repair. Nat Genet. 2010;42:245-9 pubmed 出版商
Vierbuchen T, Ostermeier A, Pang Z, Kokubu Y, Sudhof T, Wernig M. Direct conversion of fibroblasts to functional neurons by defined factors. Nature. 2010;463:1035-41 pubmed 出版商
Patani R, Compston A, Puddifoot C, Wyllie D, Hardingham G, Allen N, et al. Activin/Nodal inhibition alone accelerates highly efficient neural conversion from human embryonic stem cells and imposes a caudal positional identity. PLoS ONE. 2009;4:e7327 pubmed 出版商
Ferran J, de Oliveira E, Merchan P, Sandoval J, Sánchez Arrones L, Martinez de la Torre M, et al. Genoarchitectonic profile of developing nuclear groups in the chicken pretectum. J Comp Neurol. 2009;517:405-51 pubmed 出版商
Thompson H, Andrews W, Parnavelas J, Erskine L. Robo2 is required for Slit-mediated intraretinal axon guidance. Dev Biol. 2009;335:418-26 pubmed 出版商
Hsieh Y, Yang X. Dynamic Pax6 expression during the neurogenic cell cycle influences proliferation and cell fate choices of retinal progenitors. Neural Dev. 2009;4:32 pubmed 出版商
Sansom S, Griffiths D, Faedo A, Kleinjan D, Ruan Y, Smith J, et al. The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. PLoS Genet. 2009;5:e1000511 pubmed 出版商
Du A, Hunter C, Murray J, Noble D, Cai C, Evans S, et al. Islet-1 is required for the maturation, proliferation, and survival of the endocrine pancreas. Diabetes. 2009;58:2059-69 pubmed 出版商
Das G, Choi Y, Sicinski P, Levine E. Cyclin D1 fine-tunes the neurogenic output of embryonic retinal progenitor cells. Neural Dev. 2009;4:15 pubmed 出版商
Cameron D, Pennimpede T, Petkovich M. Tulp3 is a critical repressor of mouse hedgehog signaling. Dev Dyn. 2009;238:1140-9 pubmed 出版商
Chambers S, Fasano C, Papapetrou E, Tomishima M, Sadelain M, Studer L. Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nat Biotechnol. 2009;27:275-80 pubmed 出版商
Patterson V, Damrau C, Paudyal A, Reeve B, Grimes D, Stewart M, et al. Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway. Hum Mol Genet. 2009;18:1719-39 pubmed 出版商
Nishiguchi K, Kaneko H, Nakamura M, Kachi S, Terasaki H. Generation of immature retinal neurons from proliferating cells in the pars plana after retinal histogenesis in mice with retinal degeneration. Mol Vis. 2009;15:187-99 pubmed
Way S, McKenna J, Mietzsch U, Reith R, Wu H, Gambello M. Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse. Hum Mol Genet. 2009;18:1252-65 pubmed 出版商
Puri S, Cano D, Hebrok M. A role for von Hippel-Lindau protein in pancreatic beta-cell function. Diabetes. 2009;58:433-41 pubmed 出版商
Martínez Navarrete G, Angulo A, Martín Nieto J, Cuenca N. Gradual morphogenesis of retinal neurons in the peripheral retinal margin of adult monkeys and humans. J Comp Neurol. 2008;511:557-80 pubmed 出版商
Fotaki V, Price D, Mason J. Newly identified patterns of Pax2 expression in the developing mouse forebrain. BMC Dev Biol. 2008;8:79 pubmed 出版商
Shaked M, Weissmüller K, Svoboda H, Hortschansky P, Nishino N, Wolfl S, et al. Histone deacetylases control neurogenesis in embryonic brain by inhibition of BMP2/4 signaling. PLoS ONE. 2008;3:e2668 pubmed 出版商
Poche R, Furuta Y, Chaboissier M, Schedl A, Behringer R. Sox9 is expressed in mouse multipotent retinal progenitor cells and functions in Müller glial cell development. J Comp Neurol. 2008;510:237-50 pubmed 出版商
Jiang Y, Nishimura W, Devor Henneman D, Kusewitt D, Wang H, Holloway M, et al. Postnatal expansion of the pancreatic beta-cell mass is dependent on survivin. Diabetes. 2008;57:2718-27 pubmed 出版商
Manuel M, Pratt T, Liu M, Jeffery G, Price D. Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidance. BMC Dev Biol. 2008;8:59 pubmed 出版商
Pawlisz A, Mutch C, Wynshaw Boris A, Chenn A, Walsh C, Feng Y. Lis1-Nde1-dependent neuronal fate control determines cerebral cortical size and lamination. Hum Mol Genet. 2008;17:2441-55 pubmed 出版商
Edqvist P, Lek M, Boije H, Lindbäck S, Hallböök F. Axon-bearing and axon-less horizontal cell subtypes are generated consecutively during chick retinal development from progenitors that are sensitive to follistatin. BMC Dev Biol. 2008;8:46 pubmed 出版商
Wagner M, Koschnick S, Beilke S, Frey M, Adler G, Schmid R. Selective expansion of the beta-cell compartment in the pancreas of keratinocyte growth factor transgenic mice. Am J Physiol Gastrointest Liver Physiol. 2008;294:G1139-47 pubmed 出版商
Tuoc T, Stoykova A. Er81 is a downstream target of Pax6 in cortical progenitors. BMC Dev Biol. 2008;8:23 pubmed 出版商
Patthey C, Gunhaga L, Edlund T. Early development of the central and peripheral nervous systems is coordinated by Wnt and BMP signals. PLoS ONE. 2008;3:e1625 pubmed 出版商
Stanke J, Lehman B, Fischer A. Muscarinic signaling influences the patterning and phenotype of cholinergic amacrine cells in the developing chick retina. BMC Dev Biol. 2008;8:13 pubmed 出版商
Nomura T, Takahashi M, Hara Y, Osumi N. Patterns of neurogenesis and amplitude of Reelin expression are essential for making a mammalian-type cortex. PLoS ONE. 2008;3:e1454 pubmed 出版商
Theveneau E, Duband J, Altabef M. Ets-1 confers cranial features on neural crest delamination. PLoS ONE. 2007;2:e1142 pubmed
Chen B, Cepko C. Requirement of histone deacetylase activity for the expression of critical photoreceptor genes. BMC Dev Biol. 2007;7:78 pubmed
Ma L, Cantrup R, Varrault A, Colak D, Klenin N, Gotz M, et al. Zac1 functions through TGFbetaII to negatively regulate cell number in the developing retina. Neural Dev. 2007;2:11 pubmed
Ahnfelt Rønne J, Hald J, Bødker A, Yassin H, Serup P, Hecksher Sørensen J. Preservation of proliferating pancreatic progenitor cells by Delta-Notch signaling in the embryonic chicken pancreas. BMC Dev Biol. 2007;7:63 pubmed
Pirity M, Wang W, Wolf L, Tamm E, Schreiber Agus N, Cvekl A. Rybp, a polycomb complex-associated protein, is required for mouse eye development. BMC Dev Biol. 2007;7:39 pubmed
Donner A, Ko F, Episkopou V, Maas R. Pax6 is misexpressed in Sox1 null lens fiber cells. Gene Expr Patterns. 2007;7:606-13 pubmed
Spence J, Madhavan M, Aycinena J, Del Rio Tsonis K. Retina regeneration in the chick embryo is not induced by spontaneous Mitf downregulation but requires FGF/FGFR/MEK/Erk dependent upregulation of Pax6. Mol Vis. 2007;13:57-65 pubmed
Lesaffre B, Joliot A, Prochiantz A, Volovitch M. Direct non-cell autonomous Pax6 activity regulates eye development in the zebrafish. Neural Dev. 2007;2:2 pubmed
Shibasaki K, Takebayashi H, Ikenaka K, Feng L, Gan L. Expression of the basic helix-loop-factor Olig2 in the developing retina: Olig2 as a new marker for retinal progenitors and late-born cells. Gene Expr Patterns. 2007;7:57-65 pubmed
Pinson J, Simpson T, Mason J, Price D. Positive autoregulation of the transcription factor Pax6 in response to increased levels of either of its major isoforms, Pax6 or Pax6(5a), in cultured cells. BMC Dev Biol. 2006;6:25 pubmed
Ouyang J, Shen Y, Yeh L, Li W, Coyle B, Liu C, et al. Pax6 overexpression suppresses cell proliferation and retards the cell cycle in corneal epithelial cells. Invest Ophthalmol Vis Sci. 2006;47:2397-407 pubmed
Tyas D, Simpson T, Carr C, Kleinjan D, van Heyningen V, Mason J, et al. Functional conservation of Pax6 regulatory elements in humans and mice demonstrated with a novel transgenic reporter mouse. BMC Dev Biol. 2006;6:21 pubmed
Lowell S, Benchoua A, Heavey B, Smith A. Notch promotes neural lineage entry by pluripotent embryonic stem cells. PLoS Biol. 2006;4:e121 pubmed
Ikeda H, Osakada F, Watanabe K, Mizuseki K, Haraguchi T, Miyoshi H, et al. Generation of Rx+/Pax6+ neural retinal precursors from embryonic stem cells. Proc Natl Acad Sci U S A. 2005;102:11331-6 pubmed
Englund C, Fink A, Lau C, Pham D, Daza R, Bulfone A, et al. Pax6, Tbr2, and Tbr1 are expressed sequentially by radial glia, intermediate progenitor cells, and postmitotic neurons in developing neocortex. J Neurosci. 2005;25:247-51 pubmed
Bulgakov O, Eggenschwiler J, Hong D, Anderson K, Li T. FKBP8 is a negative regulator of mouse sonic hedgehog signaling in neural tissues. Development. 2004;131:2149-59 pubmed
Qiu Y, Guo M, Huang S, Stein R. Acetylation of the BETA2 transcription factor by p300-associated factor is important in insulin gene expression. J Biol Chem. 2004;279:9796-802 pubmed
Collinson J, Quinn J, Hill R, West J. The roles of Pax6 in the cornea, retina, and olfactory epithelium of the developing mouse embryo. Dev Biol. 2003;255:303-12 pubmed
Lim Y, Golden J. Expression pattern of cLhx2b, cZic1 and cZic3 in the developing chick diencephalon. Mech Dev. 2002;115:147-50 pubmed
Hussain M, Miller C, Habener J. Brn-4 transcription factor expression targeted to the early developing mouse pancreas induces ectopic glucagon gene expression in insulin-producing beta cells. J Biol Chem. 2002;277:16028-32 pubmed
Kawakami A, Kimura Kawakami M, Nomura T, Fujisawa H. Distributions of PAX6 and PAX7 proteins suggest their involvement in both early and late phases of chick brain development. Mech Dev. 1997;66:119-30 pubmed
Ericson J, Rashbass P, Schedl A, Brenner Morton S, Kawakami A, van Heyningen V, et al. Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling. Cell. 1997;90:169-80 pubmed
产品信息
内部号码 :
2821
名称 :
PAX6
Depositor Name :
Kawakami, A.
Depositor Institution :
Tokyo Institute of Technology
Date Deposited :
7/9/97
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
抗原 :
Pax6
抗原物种 :
宿主物种 :
小鼠
抗体亚型 :
MIgG1, kappa light chain
Isotype for catalog (legacy) :
IgG1, kappa light chain
Positive Tested Species Reactivity :
Amphibian,Avian,Fish,Human,Lizard,Mouse,Opossum,Planaria,Rat,Turtle,Zebrafish
Species Tested (legacy) :
chicken, mouse, rat, human, planaria
Initial Publication Pubmed ID :
9230312 9376315
Depositor Notes (Special Instructions) :
This antibody recognizes a transcription factor important in neurodevelopment and differentiation of islet cells in the pancreas.
Collections :
Cell markers,Human,Neurodevelopment,Stem cell,Transcription factors
搜索关键词 :
Kawakami, Atsushi, Pax6, Chicken, MIgG1, kappa light chain, pax6, PAX-6, AB_528427, Monoclonal, astrocytes, avian, human, mouse, rat, zebrafish, turtle, lizard
抗原分子量 :
Predicted: 48 kDa; Apparent: 38, 40 and 46, 48 kDa
基因 :
Pax-6
Alternate Gene Name(s) :
PAX6
UniProt数据库编号 :
O42348
抗体登记处号码 :
AB_528427
免疫原 :
Recombinant partial protein (N-terminal region, aa 1-223)
免疫原序列 :
Partial protein
克隆性 :
单克隆
Myeloma Strain :
P3U1
表位定位 :
Yes
Epitope Location or Sequence :
N末端地区, 氨基酸1-223
表位定位Pubmed登录号 :
9376315
Recommended Applications :
Chromatin Immunoprecipitation,FACS,FFPE,Function Blocking,Gel Supershift,Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot
免疫组化PubMed IDs :
24717807 24628886 24592933 23180754 24404179 23213043 23968833 23500521 23353076 21681860 17229313 29230053 29669275 27151208 31328313 31369820 31376504
免疫荧光PubMed IDs :
24443177 23382203 23420872 22891678 22745311 22491411 22115999 23166838 22037235 21658587 21681860 28800946 29174332 29235536 25146370 26053997 30466480 31412250
免疫印迹PubMed IDs :
23766144 22232084 21576358 21233129 20698747 18372394 16723449 15105374 14701848 11834725
免疫沉淀PubMed IDs :
14701848
染色质免疫沉淀 PubMed IDs :
24290376
FFPE PubMed IDs :
12049780 17306631 12648492 31328313
Function Blocking Pubmed IDs :
22028031
流式细胞仪PubMed IDs :
21699412 20178645 23804753 21997878 24318875
Gel Supershift Pubmed IDs :
22583899 20943817
PubMed IDs :
24527395 17229313
DSHB增长培养基 :
Iscove's
公司信息
Developmental Studies Hybridoma Bank
University of Iowa
dshb@uiowa.edu
http://dshb.biology.uiowa.edu
公司总部: 美国
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构,为生命科学研究领域及诊断领域,提供高质量的抗体等产品。