产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
ZO-1;紧密连接蛋白1
目录 :
R26.4C
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
R26.4C
反应物种 :
小鼠, 大鼠, , 斑马鱼
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-自由浮动切片
文章摘录数: 39
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 1:200; 图 2c, 3a
Kindt K, Akturk A, Jarysta A, Day M, Beirl A, Flonard M, et al. EMX2-GPR156-Gαi reverses hair cell orientation in mechanosensory epithelia. Nat Commun. 2021;12:2861 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 5e
Jin Z, Liang F, Yang J, Mei W. hnRNP I regulates neonatal immune adaptation and prevents colitis and colorectal cancer. PLoS Genet. 2017;13:e1006672 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6b
Huang H, Liu Y, Wang L, Li W. Age-related macular degeneration phenotypes are associated with increased tumor necrosis-alpha and subretinal immune cells in aged Cxcr5 knockout mice. PLoS ONE. 2017;12:e0173716 pubmed 出版商
  • 免疫细胞化学; 犬; 1:500; 图 6d
Bernabé Rubio M, Andrés G, Casares Arias J, Fernández Barrera J, Rangel L, Reglero Real N, et al. Novel role for the midbody in primary ciliogenesis by polarized epithelial cells. J Cell Biol. 2016;214:259-73 pubmed 出版商
  • 免疫细胞化学; 犬; 图 1A
Domínguez Calderón A, Ávila Flores A, Ponce A, López Bayghen E, Calderón Salinas J, Luis Reyes J, et al. ZO-2 silencing induces renal hypertrophy through a cell cycle mechanism and the activation of YAP and the mTOR pathway. Mol Biol Cell. 2016;27:1581-95 pubmed 出版商
  • 免疫细胞化学; 犬; 1:100; 图 2d
Archibald A, Al Masri M, Liew Spilger A, McCaffrey L. Atypical protein kinase C induces cell transformation by disrupting Hippo/Yap signaling. Mol Biol Cell. 2015;26:3578-95 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:10
Morita S, Furube E, Mannari T, Okuda H, Tatsumi K, Wanaka A, et al. Heterogeneous vascular permeability and alternative diffusion barrier in sensory circumventricular organs of adult mouse brain. Cell Tissue Res. 2016;363:497-511 pubmed 出版商
Jung S, Topf H, Boie G, Trollmann R. C1 Esterase Inhibitor Reduces BBB Leakage and Apoptosis in the Hypoxic Developing Mouse Brain. Neuromolecular Med. 2019;: pubmed 出版商
Bosch Fortea M, Rodriguez Fraticelli A, Herranz G, Hachimi M, Barea M, Young J, et al. Micropattern-based platform as a physiologically relevant model to study epithelial morphogenesis and nephrotoxicity. Biomaterials. 2019;218:119339 pubmed 出版商
Marivin A, Garcia Marcos M. DAPLE and MPDZ bind to each other and cooperate to promote apical cell constriction. Mol Biol Cell. 2019;:mbcE19020091 pubmed 出版商
Bernascone I, González T, Barea M, Carabaña C, Hachimi M, Bosch Fortea M, et al. Sfrp3 modulates stromal-epithelial crosstalk during mammary gland development by regulating Wnt levels. Nat Commun. 2019;10:2481 pubmed 出版商
Chatterjee S, Halaoui R, Deagle R, Rejon C, McCaffrey L. Numb regulates cell tension required for mammary duct elongation. Biol Open. 2019;8: pubmed 出版商
Marivin A, Morozova V, Walawalkar I, Leyme A, Kretov D, Cifuentes D, et al. GPCR-independent activation of G proteins promotes apical cell constriction in vivo. J Cell Biol. 2019;218:1743-1763 pubmed 出版商
Stroukov W, Rösch A, Schwan C, Jeney A, Römer W, Thuenauer R. Synchronizing Protein Traffic to the Primary Cilium. Front Genet. 2019;10:163 pubmed 出版商
Lapierre L, Manning E, Mitchell K, Caldwell C, Goldenring J. Interaction of phosphorylated Rab11-FIP2 with Eps15 regulates apical junction composition. Mol Biol Cell. 2017;28:1088-1100 pubmed 出版商
Aragon M, Topper L, Tyler C, Sanchez B, Zychowski K, Young T, et al. Serum-borne bioactivity caused by pulmonary multiwalled carbon nanotubes induces neuroinflammation via blood-brain barrier impairment. Proc Natl Acad Sci U S A. 2017;114:E1968-E1976 pubmed 出版商
Tran J, Zheng X, Zheng Y. Lamin-B1 contributes to the proper timing of epicardial cell migration and function during embryonic heart development. Mol Biol Cell. 2016;27:3956-3963 pubmed
McGreevy E, Vijayraghavan D, Davidson L, Hildebrand J. Shroom3 functions downstream of planar cell polarity to regulate myosin II distribution and cellular organization during neural tube closure. Biol Open. 2015;4:186-96 pubmed 出版商
Nagatake T, Fujita H, Minato N, Hamazaki Y. Enteroendocrine cells are specifically marked by cell surface expression of claudin-4 in mouse small intestine. PLoS ONE. 2014;9:e90638 pubmed 出版商
Antosova B, Smolikova J, Borkovcova R, Strnad H, Lachova J, Machon O, et al. Ectopic activation of Wnt/?-catenin signaling in lens fiber cells results in cataract formation and aberrant fiber cell differentiation. PLoS ONE. 2013;8:e78279 pubmed 出版商
Zhang J, Neal J, Lian G, Hu J, Lu J, Sheen V. Filamin A regulates neuronal migration through brefeldin A-inhibited guanine exchange factor 2-dependent Arf1 activation. J Neurosci. 2013;33:15735-46 pubmed 出版商
Maiers J, Peng X, Fanning A, DeMali K. ZO-1 recruitment to ?-catenin--a novel mechanism for coupling the assembly of tight junctions to adherens junctions. J Cell Sci. 2013;126:3904-15 pubmed 出版商
Adams M, Simms R, Abdelhamed Z, Dawe H, Szymanska K, Logan C, et al. A meckelin-filamin A interaction mediates ciliogenesis. Hum Mol Genet. 2012;21:1272-86 pubmed 出版商
Garay E, Patino Lopez G, Islas S, Alarcón L, Canche Pool E, Valle Rios R, et al. CRTAM: A molecule involved in epithelial cell adhesion. J Cell Biochem. 2010;111:111-22 pubmed 出版商
Booker Dwyer T, Hirsh S, Zhao H. A unique cell population in the mouse olfactory bulb displays nuclear beta-catenin signaling during development and olfactory sensory neuron regeneration. Dev Neurobiol. 2008;68:859-69 pubmed 出版商
Hernandez S, Chavez Munguia B, Gonzalez Mariscal L. ZO-2 silencing in epithelial cells perturbs the gate and fence function of tight junctions and leads to an atypical monolayer architecture. Exp Cell Res. 2007;313:1533-47 pubmed
Tumbarello D, Turner C. Hic-5 contributes to epithelial-mesenchymal transformation through a RhoA/ROCK-dependent pathway. J Cell Physiol. 2007;211:736-47 pubmed
Bohl J, Brimer N, Lyons C, Vande Pol S. The stardust family protein MPP7 forms a tripartite complex with LIN7 and DLG1 that regulates the stability and localization of DLG1 to cell junctions. J Biol Chem. 2007;282:9392-400 pubmed 出版商
Chen H, Tung Y, Li B, Iqbal K, Grundke Iqbal I. Trophic factors counteract elevated FGF-2-induced inhibition of adult neurogenesis. Neurobiol Aging. 2007;28:1148-62 pubmed
Swetloff A, Greenwood S, Wade A, Ferretti P. Growth of choroid plexus epithelium vesicles in vitro depends on secretory activity. J Cell Physiol. 2006;208:549-55 pubmed
Villanueva S, Cespedes C, Vio C. Ischemic acute renal failure induces the expression of a wide range of nephrogenic proteins. Am J Physiol Regul Integr Comp Physiol. 2006;290:R861-70 pubmed
Gresh L, Bourachot B, Reimann A, Guigas B, Fiette L, Garbay S, et al. The SWI/SNF chromatin-remodeling complex subunit SNF5 is essential for hepatocyte differentiation. EMBO J. 2005;24:3313-24 pubmed
Wagner M, Blazer Yost B, Boyd White J, Srirangam A, Pennington J, Bennett S. Expression of the unconventional myosin Myo1c alters sodium transport in M1 collecting duct cells. Am J Physiol Cell Physiol. 2005;289:C120-9 pubmed
Talbott J, Loy D, Liu Y, Qiu M, Bunge M, Rao M, et al. Endogenous Nkx2.2+/Olig2+ oligodendrocyte precursor cells fail to remyelinate the demyelinated adult rat spinal cord in the absence of astrocytes. Exp Neurol. 2005;192:11-24 pubmed
Mendoza Rodriguez C, Gonzalez Mariscal L, Cerbón M. Changes in the distribution of ZO-1, occludin, and claudins in the rat uterine epithelium during the estrous cycle. Cell Tissue Res. 2005;319:315-30 pubmed
Oshima R, Lesperance J, Munoz V, Hebbard L, Ranscht B, Sharan N, et al. Angiogenic acceleration of Neu induced mammary tumor progression and metastasis. Cancer Res. 2004;64:169-79 pubmed
Brook G, Lawrence J, Shah B, Raisman G. Extrusion transplantation of Schwann cells into the adult rat thalamus induces directional host axon growth. Exp Neurol. 1994;126:31-43 pubmed
Stevenson B, Siliciano J, Mooseker M, Goodenough D. Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia. J Cell Biol. 1986;103:755-66 pubmed
Anderson J, Stevenson B, Jesaitis L, Goodenough D, Mooseker M. Characterization of ZO-1, a protein component of the tight junction from mouse liver and Madin-Darby canine kidney cells. J Cell Biol. 1988;106:1141-9 pubmed
产品信息
内部号码 :
3490
名称 :
R26.4C
Depositor Name :
Goodenough, D.A.
Depositor Institution :
Harvard Medical School
Date Deposited :
3/29/89
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
抗原 :
ZO-1;紧密连接蛋白1
抗原物种 :
小鼠
宿主物种 :
大鼠
抗体亚型 :
RIgG1, kappa light chain
Isotype for catalog (legacy) :
IgG1, kappa light chain
Positive Tested Species Reactivity :
狗, 鱼类, 小鼠, 猪, 大鼠, 斑马鱼
Species Tested (legacy) :
positive: rat, mouse, dog, pig; negative: human
Initial Publication Pubmed ID :
3528172
Depositor Notes (Special Instructions) :
The epitope bound by this antibody is on the cytoplasmic face of plasma membrane at tight junctions.
Collections :
Cell signaling
搜索关键词 :
Goodenough, Daniel A., ZO-1 tight junction protein, Mouse, RIgG1, kappa light chain, Rat/Mouse/Canine/Porcine/Zebrafish, Tjp1, Zo1, AB_2205518, monoclonal, Tjp-1
抗原分子量 :
194kD Predicted; 225k kD on SDS-PAGE
基因 :
紧密连接蛋白-1
Alternate Gene Name(s) :
Zo1
UniProt数据库编号 :
F1M4A0
抗体登记处号码 :
AB_2205518
免疫原 :
Isolated deoxycholate-extracted plasma membrane junctional regions from liver
克隆性 :
单克隆
Myeloma Strain :
P3x63 Ag8U.1(CRL 1597)
表位定位 :
No
Recommended Applications :
免疫荧光, 免疫组化, 免疫沉淀, 免疫印迹
Immunoblotting (legacy) :
Yes
免疫组化PubMed IDs :
24603700 24089482 3528172 20556794 23813953 22121117 17237226 16138077 15716323 16741962 16284088 15558325 18327767 17374535 8157125 31414384
免疫荧光PubMed IDs :
24205179 23813953 17299801 31326655
免疫印迹PubMed IDs :
2452168 3528172 23813953
免疫沉淀PubMed IDs :
23813953
FFPE PubMed IDs :
16284088 14729621 22121117
PubMed IDs :
16859812 15698615
DSHB增长培养基 :
RPMI
References (legacy) :
J. Cell Biol. 103, 755-766.; J. Cell Biol. 106, 1141-1149.
公司信息
Developmental Studies Hybridoma Bank
University of Iowa
dshb@uiowa.edu
http://dshb.biology.uiowa.edu
公司总部: 美国
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构,为生命科学研究领域及诊断领域,提供高质量的抗体等产品。