产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
neurofilament (NF-H)
目录 :
RT97
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
RT97
反应物种 :
人类, 小鼠, 大鼠, 鸡, 牛
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
Developmental Studies Hybridoma Bank 产品网页
文章摘录数: 38
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 小鼠; 1:2000
Maggio D, Singh A, Iorgulescu J, Bleicher D, Ghosh M, Lopez M, et al. Identifying the Long-Term Role of Inducible Nitric Oxide Synthase after Contusive Spinal Cord Injury Using a Transgenic Mouse Model. Int J Mol Sci. 2017;18: pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:800
van der Zee J, Gijselinck I, Van Mossevelde S, Perrone F, Dillen L, Heeman B, et al. TBK1 Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis. Hum Mutat. 2017;38:297-309 pubmed 出版商
  • 免疫组化; 大鼠; 1:50
Gaillard F, Kuny S, Sauve Y. Retinal distribution of Disabled-1 in a diurnal murine rodent, the Nile grass rat Arvicanthis niloticus. Exp Eye Res. 2014;125:236-43 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:2000
Tripathi R, McTigue D. Chronically increased ciliary neurotrophic factor and fibroblast growth factor-2 expression after spinal contusion in rats. J Comp Neurol. 2008;510:129-44 pubmed 出版商
Church J, Milich L, Lerch J, Popovich P, McTigue D. E6020, a synthetic TLR4 agonist, accelerates myelin debris clearance, Schwann cell infiltration, and remyelination in the rat spinal cord. Glia. 2017;65:883-899 pubmed 出版商
Santos D, Gonzalez Perez F, Giudetti G, Micera S, Udina E, del Valle J, et al. Preferential Enhancement of Sensory and Motor Axon Regeneration by Combining Extracellular Matrix Components with Neurotrophic Factors. Int J Mol Sci. 2016;18: pubmed 出版商
Harwell C, Coleman M. Synaptophysin depletion and intraneuronal A? in organotypic hippocampal slice cultures from huAPP transgenic mice. Mol Neurodegener. 2016;11:44 pubmed 出版商
De Groef L, Andries L, Lemmens K, Van Hove I, Moons L. Matrix metalloproteinases in the mouse retina: a comparative study of expression patterns and MMP antibodies. BMC Ophthalmol. 2015;15:187 pubmed 出版商
Kim K, Son K, Palmore G. Neuron Image Analyzer: Automated and Accurate Extraction of Neuronal Data from Low Quality Images. Sci Rep. 2015;5:17062 pubmed 出版商
Kastriti M, Sargiannidou I, Kleopa K, Karagogeos D. Differential modulation of the juxtaparanodal complex in Multiple Sclerosis. Mol Cell Neurosci. 2015;67:93-103 pubmed 出版商
Tsai Y, Lu B, Bakondi B, Girman S, Sahabian A, Sareen D, et al. Human iPSC-Derived Neural Progenitors Preserve Vision in an AMD-Like Model. Stem Cells. 2015;33:2537-49 pubmed 出版商
Solin S, Wang Y, Mauldin J, Schultz L, Lincow D, Brodskiy P, et al. Molecular and cellular characterization of a zebrafish optic pathway tumor line implicates glia-derived progenitors in tumorigenesis. PLoS ONE. 2014;9:e114888 pubmed 出版商
Mihailovska E, Raith M, Valencia R, Fischer I, Al Banchaabouchi M, Herbst R, et al. Neuromuscular synapse integrity requires linkage of acetylcholine receptors to postsynaptic intermediate filament networks via rapsyn-plectin 1f complexes. Mol Biol Cell. 2014;25:4130-49 pubmed 出版商
García Ayuso D, Salinas Navarro M, Nadal Nicolás F, Ortín Martínez A, Agudo Barriuso M, Vidal Sanz M, et al. Sectorial loss of retinal ganglion cells in inherited photoreceptor degeneration is due to RGC death. Br J Ophthalmol. 2014;98:396-401 pubmed 出版商
Viehöfer A, Shinohara Y, Sprecher C, Boszczyk B, Buettner A, Benjamin M, et al. The molecular composition of the extracellular matrix of the human iliolumbar ligament. Spine J. 2015;15:1325-31 pubmed 出版商
Barbour H, Plant C, Harvey A, Plant G. Tissue sparing, behavioral recovery, supraspinal axonal sparing/regeneration following sub-acute glial transplantation in a model of spinal cord contusion. BMC Neurosci. 2013;14:106 pubmed 出版商
Maden M, Manwell L, Ormerod B. Proliferation zones in the axolotl brain and regeneration of the telencephalon. Neural Dev. 2013;8:1 pubmed 出版商
Marei H, Ahmed A, Michetti F, Pescatori M, Pallini R, Casalbore P, et al. Gene expression profile of adult human olfactory bulb and embryonic neural stem cell suggests distinct signaling pathways and epigenetic control. PLoS ONE. 2012;7:e33542 pubmed 出版商
García Ayuso D, Salinas Navarro M, Agudo Barriuso M, Alarcón Martínez L, Vidal Sanz M, Villegas Pérez M. Retinal ganglion cell axonal compression by retinal vessels in light-induced retinal degeneration. Mol Vis. 2011;17:1716-33 pubmed
De Repentigny Y, Ferrier A, Ryan S, Sato T, Kothary R. Motor unit abnormalities in Dystonia musculorum mice. PLoS ONE. 2011;6:e21093 pubmed 出版商
Albersen M, Fandel T, Zhang H, Banie L, Lin G, De Ridder D, et al. Pentoxifylline promotes recovery of erectile function in a rat model of postprostatectomy erectile dysfunction. Eur Urol. 2011;59:286-96 pubmed 出版商
Salinas Navarro M, Alarcón Martínez L, Valiente Soriano F, Ortín Martínez A, Jiménez López M, Avilés Trigueros M, et al. Functional and morphological effects of laser-induced ocular hypertension in retinas of adult albino Swiss mice. Mol Vis. 2009;15:2578-98 pubmed
Kuny S, Gaillard F, Mema S, Freund P, Zhang K, Macdonald I, et al. Inner retina remodeling in a mouse model of stargardt-like macular dystrophy (STGD3). Invest Ophthalmol Vis Sci. 2010;51:2248-62 pubmed 出版商
Casalbore P, Budoni M, Ricci Vitiani L, Cenciarelli C, Petrucci G, Milazzo L, et al. Tumorigenic potential of olfactory bulb-derived human adult neural stem cells associates with activation of TERT and NOTCH1. PLoS ONE. 2009;4:e4434 pubmed 出版商
Veeranna -, Lee J, Pareek T, Jaffee H, Boland B, Vinod K, et al. Neurofilament tail phosphorylation: identity of the RT-97 phosphoepitope and regulation in neurons by cross-talk among proline-directed kinases. J Neurochem. 2008;107:35-49 pubmed 出版商
Gaillard F, Bonfield S, Gilmour G, Kuny S, Mema S, Martin B, et al. Retinal anatomy and visual performance in a diurnal cone-rich laboratory rodent, the Nile grass rat (Arvicanthis niloticus). J Comp Neurol. 2008;510:525-38 pubmed 出版商
Jiang S, Bendjelloul F, Ballerini P, D Alimonte I, Nargi E, Jiang C, et al. Guanosine reduces apoptosis and inflammation associated with restoration of function in rats with acute spinal cord injury. Purinergic Signal. 2007;3:411-21 pubmed 出版商
Marco Gomariz M, Hurtado Montalbán N, Vidal Sanz M, Lund R, Villegas Pérez M. Phototoxic-induced photoreceptor degeneration causes retinal ganglion cell degeneration in pigmented rats. J Comp Neurol. 2006;498:163-79 pubmed
Bampton E, Taylor J. Effects of Schwann cell secreted factors on PC12 cell neuritogenesis and survival. J Neurobiol. 2005;63:29-48 pubmed
Hwang I, DO S, Yoo K, Kim D, Cho J, Kwon Y, et al. Chronological alterations of neurofilament 150 immunoreactivity in the gerbil hippocampus and dentate gyrus after transient forebrain ischemia. Brain Res. 2004;1016:119-28 pubmed
Young H, Black A. Adult stem cells. Anat Rec A Discov Mol Cell Evol Biol. 2004;276:75-102 pubmed
Young H. Existence of reserve quiescent stem cells in adults, from amphibians to humans. Curr Top Microbiol Immunol. 2004;280:71-109 pubmed
Young H, Duplaa C, Young T, Floyd J, Reeves M, Davis K, et al. Clonogenic analysis reveals reserve stem cells in postnatal mammals: I. Pluripotent mesenchymal stem cells. Anat Rec. 2001;263:350-60 pubmed
Walro J, Wang J, Story G. Afferent-inherent regulation of myosin heavy chain isoforms in rat muscle spindles. Muscle Nerve. 1997;20:1549-60 pubmed
Murphy A, Breen K, Long A, Feighery C, Casey E, Kelleher D. Neurofilament expression in human T lymphocytes. Immunology. 1993;79:167-70 pubmed
Wood J, Anderton B. Monoclonal antibodies to mammalian neurofilaments. Biosci Rep. 1981;1:263-8 pubmed
Anderton B, Breinburg D, Downes M, Green P, Tomlinson B, Ulrich J, et al. Monoclonal antibodies show that neurofibrillary tangles and neurofilaments share antigenic determinants. Nature. 1982;298:84-6 pubmed
Miller C, Brion J, Calvert R, Chin T, Eagles P, Downes M, et al. Alzheimer's paired helical filaments share epitopes with neurofilament side arms. EMBO J. 1986;5:269-76 pubmed
产品信息
内部号码 :
1156
名称 :
RT97
Depositor Name :
木材, J
Depositor Institution :
Sandoz Institute for Medical Research
Date Deposited :
7/30/87
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
抗原 :
neurofilament (NF-H)
抗原物种 :
大鼠
宿主物种 :
小鼠
抗体亚型 :
MIgG1
Isotype for catalog (legacy) :
IgG1
Positive Tested Species Reactivity :
牛, 鸡, 人类, 小鼠, 大鼠
Species Tested (legacy) :
人类, 鸡, 大鼠
Initial Publication Pubmed ID :
7028152
Depositor Notes (Special Instructions) :
The antibody strongly recognizes polyphosphorylated epitopes on neurofilaments (and to a much lesser extent, on other molecules, e. g. rhodopsin and histones).
Collections :
Cell markers,Cytoskeleton,Human,Neurodevelopment,Stem cell
搜索关键词 :
Wood, J., neurofilament (NF-H), Rat, MIgG1, Human/Chicken/Rat/Bovine/Mouse, NEFH, KIAA0845, NFH, AB_528399, monoclonal, Cytoskeletal elements/Human/Stem cell/Cell markers/Neurodevelopment, Immunohistochemistry/Immunofluorescence/Western Blot/FACS
抗原分子量 :
Predicted: 112 kDa; Apparent: 200 kDa
基因 :
NEFH
Alternate Gene Name(s) :
KIAA0845, NFH
UniProt数据库编号 :
F1ND22
抗体登记处号码 :
AB_528399
免疫原 :
Semi-purified neurofilaments from rat brain homogenate.
免疫原序列 :
全长蛋白
克隆性 :
单克隆
Myeloma Strain :
X63.Ag8.653
表位定位 :
Yes
Epitope Location or Sequence :
Phospho-epitopes on the tail domain of neurofilament heavy (and to a lesser extent, neurofilament medium) at KSPXK or KSPXXXK motifs.
表位定位Pubmed登录号 :
18715269
Recommended Applications :
流式细胞仪, 免疫荧光, 免疫组化, 免疫印迹
免疫组化PubMed IDs :
6178036 24139866 14699636 14594208 9390668 11500811 8509137 28251686
免疫荧光PubMed IDs :
15702477 18680202 19933199 21036464 18715269 25869002 26070930 26714639 31386177 31421150
免疫印迹PubMed IDs :
6178036 15702477 18715269 2423324 15234260 27287430 8509137
流式细胞仪PubMed IDs :
8509137
其他信息 :
RT97 reacts with neurofibrillary tangles and plaques [PMID 6178036]. RT97 cross-reacts with neurofilament medium. RT97 has been used as a cell marker for neurons.
DSHB增长培养基 :
Iscove's
References (legacy) :
Biosci. Rep. 1, 263-268.; Nature 298, 84-86.; Anat. Rec. 249, 32-43.; Muscle Nerve 20, 1549-1560.; Anat. Rec. 263, 350-360.; Curr. Top. Microbiol. Immunol. 280, 71-109.; Anat. Rec. Part A 276A, 75-102.; J. Neurobiol. 63, 29-48.; J. Comp. Neurol. 510, 525-538.; Invest. Ophthalmol. Vis. Sci. 51(4), 2248-2262.; Eur. Urol. doi:10.1016/j.eururo.2010.10.034 In press
更多信息或购买 :
Developmental Studies Hybridoma Bank 产品网页
公司信息
Developmental Studies Hybridoma Bank
University of Iowa
dshb@uiowa.edu
http://dshb.biology.uiowa.edu
公司总部: 美国
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构，为生命科学研究领域及诊断领域，提供高质量的抗体等产品。