产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
泛素相关的修饰因子-1, 氨基酸57-67
目录 :
SUMO-1 21C7
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
SUMO-1 21C7
反应物种 :
人类, 小鼠, 大鼠, 鸡, 斑马鱼
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀
更多信息或购买 :
Developmental Studies Hybridoma Bank 产品网页
文章摘录数: 17
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 图 1
  • 免疫印迹; 小鼠; 图 1
Zhang L, Liu X, Sheng H, Liu S, Li Y, Zhao J, et al. Neuron-specific SUMO knockdown suppresses global gene expression response and worsens functional outcome after transient forebrain ischemia in mice. Neuroscience. 2017;343:190-212 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 1b
Ghosh H, Auguadri L, Battaglia S, Simone Thirouin Z, Zemoura K, Messner S, et al. Several posttranslational modifications act in concert to regulate gephyrin scaffolding and GABAergic transmission. Nat Commun. 2016;7:13365 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1
Juárez Vicente F, Luna Pelaez N, Garcia Dominguez M. The Sumo protease Senp7 is required for proper neuronal differentiation. Biochim Biophys Acta. 2016;1863:1490-8 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Mendes A, Grou C, Azevedo J, Pinto M. Evaluation of the activity and substrate specificity of the human SENP family of SUMO proteases. Biochim Biophys Acta. 2016;1863:139-47 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:250; 图 1
Craig T, Anderson D, Evans A, Girach F, Henley J. SUMOylation of Syntaxin1A regulates presynaptic endocytosis. Sci Rep. 2015;5:17669 pubmed 出版商
  • 免疫印迹; 大鼠
Blakeslee W, Wysoczynski C, Fritz K, Nyborg J, Churchill M, McKinsey T. Class I HDAC inhibition stimulates cardiac protein SUMOylation through a post-translational mechanism. Cell Signal. 2014;26:2912-20 pubmed 出版商
  • 免疫印迹; 人类
Berndt A, Wilkinson K, Heimann M, Bishop P, Henley J. In vivo characterization of the properties of SUMO1-specific monobodies. Biochem J. 2013;456:385-95 pubmed 出版商
Chanda A, Chan A, Deng L, Kornaga E, Enwere E, Morris D, et al. Identification of the SUMO E3 ligase PIAS1 as a potential survival biomarker in breast cancer. PLoS ONE. 2017;12:e0177639 pubmed 出版商
Fujiwara K, Hasegawa K, Oka M, Yoneda Y, Yoshikawa K. Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system. Genes Cells. 2016;21:1176-1194 pubmed 出版商
Ristic M, Brockly F, Piechaczyk M, Bossis G. Detection of Protein-Protein Interactions and Posttranslational Modifications Using the Proximity Ligation Assay: Application to the Study of the SUMO Pathway. Methods Mol Biol. 2016;1449:279-90 pubmed 出版商
Eisenhardt N, Chaugule V, Koidl S, Droescher M, Dogan E, Rettich J, et al. A new vertebrate SUMO enzyme family reveals insights into SUMO-chain assembly. Nat Struct Mol Biol. 2015;22:959-67 pubmed 出版商
Bossis G, Sarry J, Kifagi C, Ristic M, Saland E, Vergez F, et al. The ROS/SUMO axis contributes to the response of acute myeloid leukemia cells to chemotherapeutic drugs. Cell Rep. 2014;7:1815-23 pubmed 出版商
Barysch S, Dittner C, Flotho A, Becker J, Melchior F. Identification and analysis of endogenous SUMO1 and SUMO2/3 targets in mammalian cells and tissues using monoclonal antibodies. Nat Protoc. 2014;9:896-909 pubmed 出版商
Becker J, Barysch S, Karaca S, Dittner C, Hsiao H, Berriel Diaz M, et al. Detecting endogenous SUMO targets in mammalian cells and tissues. Nat Struct Mol Biol. 2013;20:525-31 pubmed 出版商
Zhang X, Goeres J, Zhang H, Yen T, Porter A, Matunis M. SUMO-2/3 modification and binding regulate the association of CENP-E with kinetochores and progression through mitosis. Mol Cell. 2008;29:729-41 pubmed 出版商
Rogers R, Inselman A, Handel M, Matunis M. SUMO modified proteins localize to the XY body of pachytene spermatocytes. Chromosoma. 2004;113:233-43 pubmed
Matunis M, Coutavas E, Blobel G. A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex. J Cell Biol. 1996;135:1457-70 pubmed
产品信息
内部号码 :
5944
名称 :
SUMO-1 21C7
Depositor Name :
Matunis, M.
Depositor Institution :
Johns Hopkins University School of Medicine
Date Deposited :
4/27/09
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
抗原 :
泛素相关的修饰因子-1, 氨基酸57-67
抗原物种 :
人类
宿主物种 :
小鼠
抗体亚型 :
MIgG1
Isotype for catalog (legacy) :
IgG1
Positive Tested Species Reactivity :
鸡, 人类, 小鼠, 大鼠, 蛙, 斑马鱼
Species Tested (legacy) :
都是脊椎动物试验
Initial Publication Pubmed ID :
8978815
Depositor Notes (Special Instructions) :
This antibody recognizes SUMO1 and SUMO1 conjugates in all vertebrate cells tested; does not cross-react with SUMO2 or SUMO3. 21C7 doesn't recognize C. elegans SUMO1.
Collections :
Cell signaling,Human,Xenopus
搜索关键词 :
Matunis, M., SUMO1, aa 57-67, Human, MIgG1, Human/Rat/Mouse/Zebrafish/Xenopus/Chicken, SUMO1, SMT3C, SMT3H3, UBL1, PIC1, DAP1, GMP1, OFC10, SENP2, AB_2198257, monoclonal, Cell signaling/Human/Xenopus, Immunoprecipitation/Immunofluorescence/Western Blot
抗原分子量 :
11 kDa
基因 :
泛素相关的修饰因子-1
Alternate Gene Name(s) :
SMT3C, SMT3H3, UBL1, PIC1, DAP1, GMP1, OFC10, SENP2
UniProt数据库编号 :
P63165
抗体登记处号码 :
AB_2198257
Synonyms (Alternate Clone Names) :
21C7
免疫原 :
Recombinant SUMO-1 (GenBank accession number AAB40390) protein with N-terminal 6xHis tag
免疫原序列 :
全长蛋白
克隆性 :
单克隆
Myeloma Strain :
SP2/0-Ag14
表位定位 :
Yes
Epitope Location or Sequence :
氨基酸57-67 VPMNSLRFLFE
表位定位Pubmed登录号 :
23503365
Recommended Applications :
免疫荧光, 免疫沉淀, 免疫印迹
Immunoblotting (legacy) :
yes
免疫组化PubMed IDs :
30948704
免疫荧光PubMed IDs :
8978815 18374647 15349788 30948704
免疫印迹PubMed IDs :
8978815 28493978 18374647 15349788 23503365 26524493 27717094 27039038 24651501 24910433 30948704
免疫沉淀PubMed IDs :
23503365 24651501
FFPE PubMed IDs :
30948704
PubMed IDs :
27613043 27819299
其他信息 :
This antibody will recognize both SUMO-1 isoforms.
DSHB增长培养基 :
Iscove's
References (legacy) :
J. Cell. Biol. 135, 1457-1470.; Chromosoma 113, 233-243.; Mol. Cell 29, 729-741.; Nat. Struct. Mol. Biol. 20, 525-531.
更多信息或购买 :
Developmental Studies Hybridoma Bank 产品网页
公司信息
Developmental Studies Hybridoma Bank
University of Iowa
dshb@uiowa.edu
http://dshb.biology.uiowa.edu
公司总部: 美国
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构，为生命科学研究领域及诊断领域，提供高质量的抗体等产品。