产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
角蛋白, 类型II/角蛋白8
目录 :
TROMA-I
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
TROMA-I
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片, 免疫印迹基因敲除验证, 免疫组化基因敲除验证
文章摘录数: 133
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 7c
Ide S, Kobayashi Y, Ide K, Strausser S, Abe K, Herbek S, et al. Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair. elife. 2021;10: pubmed 出版商
  • 免疫组化; 小鼠; 图 4e
Molina L, Zhu J, Li Q, Pradhan Sundd T, Krutsenko Y, Sayed K, et al. Compensatory hepatic adaptation accompanies permanent absence of intrahepatic biliary network due to YAP1 loss in liver progenitors. Cell Rep. 2021;36:109310 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:400; 图 s1e
Brady N, Bagadion A, Singh R, Conteduca V, Van Emmenis L, Arceci E, et al. Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer. Nat Commun. 2021;12:3372 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 5e
Benítez S, Cordero A, Santamaria P, Redondo Pedraza J, Rocha A, Collado Solé A, et al. RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness. Dev Cell. 2021;56:1727-1741.e7 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 2a, 3i
Ni N, Fang X, Li Q. Functional similarity between TGF-beta type 2 and type 1 receptors in the female reproductive tract. Sci Rep. 2021;11:9294 pubmed 出版商
  • 免疫组化; 小鼠; 图 s3b
Carstens J, Yang S, Correa de Sampaio P, Zheng X, Barua S, McAndrews K, et al. Stabilized epithelial phenotype of cancer cells in primary tumors leads to increased colonization of liver metastasis in pancreatic cancer. Cell Rep. 2021;35:108990 pubmed 出版商
  • 免疫组化; 小鼠
Wilson M, Reske J, Holladay J, Neupane S, Ngo J, Cuthrell N, et al. ARID1A Mutations Promote P300-Dependent Endometrial Invasion through Super-Enhancer Hyperacetylation. Cell Rep. 2020;33:108366 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 1:200; 图 3c
Hall B, Gleiberman A, Strom E, Krasnov P, Frescas D, Vujcic S, et al. Immune checkpoint protein VSIG4 as a biomarker of aging in murine adipose tissue. Aging Cell. 2020;19:e13219 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 1a
Neubarth N, Emanuel A, Liu Y, Springel M, Handler A, Zhang Q, et al. Meissner corpuscles and their spatially intermingled afferents underlie gentle touch perception. Science. 2020;368: pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 4a
Sun X, Are A, Annusver K, Sivan U, Jacob T, Dalessandri T, et al. Coordinated hedgehog signaling induces new hair follicles in adult skin. elife. 2020;9: pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 1b
Fan D, Chettouh Z, Consalez G, Brunet J. Taste bud formation depends on taste nerves. elife. 2019;8: pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:50; 图 2a
Abdo H, Calvo Enrique L, Lopez J, Song J, Zhang M, Usoskin D, et al. Specialized cutaneous Schwann cells initiate pain sensation. Science. 2019;365:695-699 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 5a
Saykali B, Mathiah N, Nahaboo W, Racu M, Hammou L, Defrance M, et al. Distinct mesoderm migration phenotypes in extra-embryonic and embryonic regions of the early mouse embryo. elife. 2019;8: pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:10; 图 1a
Jung H, Fattet L, Tsai J, Kajimoto T, Chang Q, Newton A, et al. Apical-basal polarity inhibits epithelial-mesenchymal transition and tumour metastasis by PAR-complex-mediated SNAI1 degradation. Nat Cell Biol. 2019;21:359-371 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:20,000; 图 2c
Abeln M, Albers I, Peters Bernard U, Flächsig Schulz K, Kats E, Kispert A, et al. Sialic acid is a critical fetal defense against maternal complement attack. J Clin Invest. 2019;129:422-436 pubmed 出版商
  • 免疫组化; 小鼠; 1:30; 图 4a
Mao S, Park M, Cabrera R, Christin J, Karagiannis G, Oktay M, et al. Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growth. Breast Cancer Res. 2018;20:131 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 1i
Chakrabarti R, Celià Terrassa T, Kumar S, Hang X, Wei Y, Choudhury A, et al. Notch ligand Dll1 mediates cross-talk between mammary stem cells and the macrophageal niche. Science. 2018;360: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:50; 图 2e
Takai K, Drain A, Lawson D, Littlepage L, Karpuj M, Kessenbrock K, et al. Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive basal-like breast cancers. Genes Dev. 2018;32:244-257 pubmed 出版商
  • 免疫组化; 小鼠; 图 2j
Watanabe Y, Miyasaka K, Kubo A, Kida Y, Nakagawa O, Hirate Y, et al. Notch and Hippo signaling converge on Strawberry Notch 1 (Sbno1) to synergistically activate Cdx2 during specification of the trophectoderm. Sci Rep. 2017;7:46135 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 2d
Saarela U, Akram S, Desgrange A, Rak Raszewska A, Shan J, Cereghini S, et al. Novel fixed z-direction (FiZD) kidney primordia and an organoid culture system for time-lapse confocal imaging. Development. 2017;144:1113-1117 pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 s5a
Fu N, Rios A, Pal B, Law C, Jamieson P, Liu R, et al. Identification of quiescent and spatially restricted mammary stem cells that are hormone responsive. Nat Cell Biol. 2017;19:164-176 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 1:20; 图 6b
Wu J, Platero Luengo A, Sakurai M, Sugawara A, Gil M, Yamauchi T, et al. Interspecies Chimerism with Mammalian Pluripotent Stem Cells. Cell. 2017;168:473-486.e15 pubmed 出版商
  • 免疫组化; 小鼠; 1:50; 图 s3
Abraira V, Kuehn E, Chirila A, Springel M, Toliver A, Zimmerman A, et al. The Cellular and Synaptic Architecture of the Mechanosensory Dorsal Horn. Cell. 2017;168:295-310.e19 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 6c
Lloyd Lewis B, Davis F, Harris O, Hitchcock J, Lourenco F, Pasche M, et al. Imaging the mammary gland and mammary tumours in 3D: optical tissue clearing and immunofluorescence methods. Breast Cancer Res. 2016;18:127 pubmed
  • 免疫组化; 小鼠; 1:500
Yang Z, Peng Y, Gopalan A, Gao D, Chen Y, Joyner A. Stromal hedgehog signaling maintains smooth muscle and hampers micro-invasive prostate cancer. Dis Model Mech. 2017;10:39-52 pubmed 出版商
  • 免疫组化; 小鼠; 图 6e
Kugler D, Flomerfelt F, Costa D, Laky K, Kamenyeva O, Mittelstadt P, et al. Systemic toxoplasma infection triggers a long-term defect in the generation and function of naive T lymphocytes. J Exp Med. 2016;213:3041-3056 pubmed
  • 免疫组化-石蜡切片; 小鼠; 1:400; 图 3b
Sizemore G, Balakrishnan S, Hammer A, Thies K, Trimboli A, Wallace J, et al. Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1. Oncogene. 2017;36:2297-2308 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:50; 图 1b
Davis F, Lloyd Lewis B, Harris O, Kozar S, Winton D, Muresan L, et al. Single-cell lineage tracing in the mammary gland reveals stochastic clonal dispersion of stem/progenitor cell progeny. Nat Commun. 2016;7:13053 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 1
Perdigoto C, Dauber K, Bar C, Tsai P, Valdes V, Cohen I, et al. Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development. PLoS Genet. 2016;12:e1006151 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 s4h
Wuidart A, Ousset M, Rulands S, Simons B, Van Keymeulen A, Blanpain C. Quantitative lineage tracing strategies to resolve multipotency in tissue-specific stem cells. Genes Dev. 2016;30:1261-77 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 图 5
  • 免疫印迹基因敲除验证; 小鼠; 图 3
Misiorek J, Lähdeniemi I, Nyström J, Paramonov V, Gullmets J, Saarento H, et al. Keratin 8-deletion induced colitis predisposes to murine colorectal cancer enforced by the inflammasome and IL-22 pathway. Carcinogenesis. 2016;37:777-786 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 s1
Mancini M, Lien E, Toker A. Oncogenic AKT1(E17K) mutation induces mammary hyperplasia but prevents HER2-driven tumorigenesis. Oncotarget. 2016;7:17301-13 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 3
Nair S, Zhang X, Chiang H, Jahid M, Wang Y, Garza P, et al. Genetic suppression reveals DNA repair-independent antagonism between BRCA1 and COBRA1 in mammary gland development. Nat Commun. 2016;7:10913 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 2
Pajoohesh Ganji A, Pal Ghosh S, Tadvalkar G, Stepp M. K14 + compound niches are present on the mouse cornea early after birth and expand after debridement wounds. Dev Dyn. 2016;245:132-43 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 3
Manda K, Tripathi P, Hsi A, Ning J, Ruzinova M, Liapis H, et al. NFATc1 promotes prostate tumorigenesis and overcomes PTEN loss-induced senescence. Oncogene. 2016;35:3282-92 pubmed 出版商
  • 免疫组化; 小鼠; 1:50; 图 5
Davila J, Laws M, Kannan A, Li Q, Taylor R, Bagchi M, et al. Rac1 Regulates Endometrial Secretory Function to Control Placental Development. PLoS Genet. 2015;11:e1005458 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:250; 图 s2
Chang C, Zhang M, Rajapakshe K, Coarfa C, Edwards D, Huang S, et al. Mammary Stem Cells and Tumor-Initiating Cells Are More Resistant to Apoptosis and Exhibit Increased DNA Repair Activity in Response to DNA Damage. Stem Cell Reports. 2015;5:378-91 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:20; 图 2
Ostrowski S, Wright M, Bolock A, Geng X, Maricich S. Ectopic Atoh1 expression drives Merkel cell production in embryonic, postnatal and adult mouse epidermis. Development. 2015;142:2533-44 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 1a
Hein S, Haricharan S, Johnston A, Toneff M, Reddy J, Dong J, et al. Luminal epithelial cells within the mammary gland can produce basal cells upon oncogenic stress. Oncogene. 2016;35:1461-7 pubmed 出版商
  • 免疫组化; 小鼠
  • 免疫组化; 人类
Franckaert D, Schlenner S, Heirman N, Gill J, Skogberg G, Ekwall O, et al. Premature thymic involution is independent of structural plasticity of the thymic stroma. Eur J Immunol. 2015;45:1535-47 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100
Chandler R, Damrauer J, Raab J, Schisler J, Wilkerson M, Didion J, et al. Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling. Nat Commun. 2015;6:6118 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:20; 图 1
Wright M, Reed Geaghan E, Bolock A, Fujiyama T, Hoshino M, Maricich S. Unipotent, Atoh1+ progenitors maintain the Merkel cell population in embryonic and adult mice. J Cell Biol. 2015;208:367-79 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:250; 图 4
Roarty K, Shore A, Creighton C, Rosen J. Ror2 regulates branching, differentiation, and actin-cytoskeletal dynamics within the mammary epithelium. J Cell Biol. 2015;208:351-66 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 3
Richardson G, Lannigan J, Macara I. Does FACS perturb gene expression?. Cytometry A. 2015;87:166-75 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100
Kunasegaran K, Ho V, Chang T, De Silva D, Bakker M, Christoffels V, et al. Transcriptional repressor Tbx3 is required for the hormone-sensing cell lineage in mammary epithelium. PLoS ONE. 2014;9:e110191 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:50; 图 2
  • 免疫组化基因敲除验证; 小鼠; 1:50; 图 1
  • 免疫印迹; 小鼠; 1:500; 图 s3
Wögenstein K, Szabo S, Lunova M, Wiche G, Haybaeck J, Strnad P, et al. Epiplakin deficiency aggravates murine caerulein-induced acute pancreatitis and favors the formation of acinar keratin granules. PLoS ONE. 2014;9:e108323 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Sato M, Kadota M, Tang B, Yang H, Yang Y, Shan M, et al. An integrated genomic approach identifies persistent tumor suppressive effects of transforming growth factor-? in human breast cancer. Breast Cancer Res. 2014;16:R57 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Mashukova A, Kozhekbaeva Z, Forteza R, Dulam V, Figueroa Y, Warren R, et al. The BAG-1 isoform BAG-1M regulates keratin-associated Hsp70 chaperoning of aPKC in intestinal cells during activation of inflammatory signaling. J Cell Sci. 2014;127:3568-77 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100
Gao Y, Bayless K, Li Q. TGFBR1 is required for mouse myometrial development. Mol Endocrinol. 2014;28:380-94 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100
Huang T, Krimm R. BDNF and NT4 play interchangeable roles in gustatory development. Dev Biol. 2014;386:308-20 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:250
Bray K, Gillette M, Young J, Loughran E, Hwang M, Sears J, et al. Cdc42 overexpression induces hyperbranching in the developing mammary gland by enhancing cell migration. Breast Cancer Res. 2013;15:R91 pubmed
  • 免疫细胞化学; 小鼠; 1:100
Stewart C, Wang Y, Bonilla Claudio M, Martin J, Gonzalez G, Taketo M, et al. CTNNB1 in mesenchyme regulates epithelial cell differentiation during Müllerian duct and postnatal uterine development. Mol Endocrinol. 2013;27:1442-54 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠
Sizemore G, Sizemore S, Pal B, Booth C, Seachrist D, Abdul Karim F, et al. FOXC1 is enriched in the mammary luminal progenitor population, but is not necessary for mouse mammary ductal morphogenesis. Biol Reprod. 2013;89:10 pubmed 出版商
  • 免疫组化; 小鼠; 1:200
Tripathi P, Wang Y, Coussens M, Manda K, Casey A, Lin C, et al. Activation of NFAT signaling establishes a tumorigenic microenvironment through cell autonomous and non-cell autonomous mechanisms. Oncogene. 2014;33:1840-9 pubmed 出版商
  • 免疫组化; 小鼠; 1:100
Patel A, Huang T, Krimm R. Lingual and palatal gustatory afferents each depend on both BDNF and NT-4, but the dependence is greater for lingual than palatal afferents. J Comp Neurol. 2010;518:3290-301 pubmed 出版商
Qi Y, Liu J, Chao J, Greer P, Li S. PTEN dephosphorylates Abi1 to promote epithelial morphogenesis. J Cell Biol. 2020;219: pubmed 出版商
Mori S, Sakakura E, Tsunekawa Y, Hagiwara M, Suzuki T, Eiraku M. Self-organized formation of developing appendages from murine pluripotent stem cells. Nat Commun. 2019;10:3802 pubmed 出版商
Wilson M, Reske J, Holladay J, Wilber G, Rhodes M, Koeman J, et al. ARID1A and PI3-kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion. Nat Commun. 2019;10:3554 pubmed 出版商
Low J, Li P, Chew E, Zhou B, Suzuki K, Zhang T, et al. Generation of Human PSC-Derived Kidney Organoids with Patterned Nephron Segments and a De Novo Vascular Network. Cell Stem Cell. 2019;25:373-387.e9 pubmed 出版商
Chatterjee S, Halaoui R, Deagle R, Rejon C, McCaffrey L. Numb regulates cell tension required for mammary duct elongation. Biol Open. 2019;8: pubmed 出版商
Tagaya H, Ishikawa K, Hosokawa Y, Kobayashi S, Ueoka Y, Shimada M, et al. A method of producing genetically manipulated mouse mammary gland. Breast Cancer Res. 2019;21:1 pubmed 出版商
Kumari A, Yokota Y, Li L, Bradley R, Mistretta C. Species generalization and differences in Hedgehog pathway regulation of fungiform and circumvallate papilla taste function and somatosensation demonstrated with sonidegib. Sci Rep. 2018;8:16150 pubmed 出版商
Okano Uchida T, Kent L, Ouseph M, McCarty B, Frank J, Kladney R, et al. Endoreduplication of the mouse genome in the absence of ORC1. Genes Dev. 2018;32:978-990 pubmed 出版商
Schroer A, Gross J, Kaski S, Wix K, Siderovski D, Vandenbeuch A, et al. Development of Full Sweet, Umami, and Bitter Taste Responsiveness Requires Regulator of G protein Signaling-21 (RGS21). Chem Senses. 2018;43:367-378 pubmed 出版商
Kogut I, McCarthy S, Pavlova M, Astling D, Chen X, Jakimenko A, et al. High-efficiency RNA-based reprogramming of human primary fibroblasts. Nat Commun. 2018;9:745 pubmed 出版商
Emmerson E, May A, Berthoin L, Cruz Pacheco N, Nathan S, Mattingly A, et al. Salivary glands regenerate after radiation injury through SOX2-mediated secretory cell replacement. EMBO Mol Med. 2018;10: pubmed 出版商
Chen P, Zhang H, Sun X, Hu Y, Jiang W, Liu Z, et al. microRNA-449a modulates medullary thymic epithelial cell differentiation. Sci Rep. 2017;7:15915 pubmed 出版商
Girnius N, Davis R. JNK Promotes Epithelial Cell Anoikis by Transcriptional and Post-translational Regulation of BH3-Only Proteins. Cell Rep. 2017;21:1910-1921 pubmed 出版商
Sreekumar A, Toneff M, Toh E, Roarty K, Creighton C, Belka G, et al. WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis. Dev Cell. 2017;43:436-448.e6 pubmed 出版商
Jain R, Sheridan J, Policheni A, Heinlein M, Gandolfo L, Dewson G, et al. A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice. Blood. 2017;130:2504-2515 pubmed 出版商
Hindman A, Mo X, Helber H, Kovalchin C, Ravichandran N, Murphy A, et al. Varying Susceptibility of the Female Mammary Gland to In Utero Windows of BPA Exposure. Endocrinology. 2017;158:3435-3447 pubmed 出版商
Speroni L, Voutilainen M, Mikkola M, Klager S, Schaeberle C, Sonnenschein C, et al. New insights into fetal mammary gland morphogenesis: differential effects of natural and environmental estrogens. Sci Rep. 2017;7:40806 pubmed 出版商
Liu Y, Wang Y, Du Z, Yan X, Zheng P, Liu Y. Fbxo30 Regulates Mammopoiesis by Targeting the Bipolar Mitotic Kinesin Eg5. Cell Rep. 2016;15:1111-1122 pubmed 出版商
Garfin P, Nguyen T, Sage J. Loss of Pten Disrupts the Thymic Epithelium and Alters Thymic Function. PLoS ONE. 2016;11:e0149430 pubmed 出版商
Biggs B, Tang T, Krimm R. Insulin-Like Growth Factors Are Expressed in the Taste System, but Do Not Maintain Adult Taste Buds. PLoS ONE. 2016;11:e0148315 pubmed 出版商
Sun X, Deng W, Li Y, Tang S, Leishman E, Bradshaw H, et al. Sustained Endocannabinoid Signaling Compromises Decidual Function and Promotes Inflammation-induced Preterm Birth. J Biol Chem. 2016;291:8231-40 pubmed 出版商
Shuda M, Guastafierro A, Geng X, Shuda Y, Ostrowski S, Lukianov S, et al. Merkel Cell Polyomavirus Small T Antigen Induces Cancer and Embryonic Merkel Cell Proliferation in a Transgenic Mouse Model. PLoS ONE. 2015;10:e0142329 pubmed 出版商
Drobysheva D, Smith B, McDowell M, Guillen K, Ekiz H, Welm B. Transformation of enriched mammary cell populations with polyomavirus middle T antigen influences tumor subtype and metastatic potential. Breast Cancer Res. 2015;17:132 pubmed 出版商
Liu Z, Ren Y, Pangas S, Adams J, Zhou W, Castrillon D, et al. FOXO1/3 and PTEN Depletion in Granulosa Cells Promotes Ovarian Granulosa Cell Tumor Development. Mol Endocrinol. 2015;29:1006-24 pubmed 出版商
Asghar M, Silvander J, Helenius T, Lähdeniemi I, Alam C, Fortelius L, et al. The amount of keratins matters for stress protection of the colonic epithelium. PLoS ONE. 2015;10:e0127436 pubmed 出版商
Helenius T, Misiorek J, Nyström J, Fortelius L, Habtezion A, Liao J, et al. Keratin 8 absence down-regulates colonocyte HMGCS2 and modulates colonic ketogenesis and energy metabolism. Mol Biol Cell. 2015;26:2298-310 pubmed 出版商
Kist R, Watson M, Crosier M, Robinson M, Fuchs J, Reichelt J, et al. The formation of endoderm-derived taste sensory organs requires a Pax9-dependent expansion of embryonic taste bud progenitor cells. PLoS Genet. 2014;10:e1004709 pubmed 出版商
LeBleu V, O Connell J, Gonzalez Herrera K, Wikman H, Pantel K, Haigis M, et al. PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis. Nat Cell Biol. 2014;16:992-1003, 1-15 pubmed 出版商
Wang D, Tiwari A, Kim M, Clemons N, Regmi N, Hodges W, et al. Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett's metaplasia. J Clin Invest. 2014;124:3767-80 pubmed 出版商
Many A, Brown A. Both canonical and non-canonical Wnt signaling independently promote stem cell growth in mammospheres. PLoS ONE. 2014;9:e101800 pubmed 出版商
Kumar L, Chou J, Yee C, Borzutzky A, Vollmann E, von Andrian U, et al. Leucine-rich repeat containing 8A (LRRC8A) is essential for T lymphocyte development and function. J Exp Med. 2014;211:929-42 pubmed 出版商
Shin K, Lim A, Odegaard J, Honeycutt J, Kawano S, Hsieh M, et al. Cellular origin of bladder neoplasia and tissue dynamics of its progression to invasive carcinoma. Nat Cell Biol. 2014;16:469-78 pubmed 出版商
Urbach A, Yermalovich A, Zhang J, Spina C, Zhu H, Perez Atayde A, et al. Lin28 sustains early renal progenitors and induces Wilms tumor. Genes Dev. 2014;28:971-82 pubmed 出版商
Woo S, Ranade S, Weyer A, Dubin A, Baba Y, Qiu Z, et al. Piezo2 is required for Merkel-cell mechanotransduction. Nature. 2014;509:622-6 pubmed 出版商
Cleary A, Leonard T, Gestl S, Gunther E. Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers. Nature. 2014;508:113-7 pubmed 出版商
Laws M, Kannan A, Pawar S, Haschek W, Bagchi M, Bagchi I. Dysregulated estrogen receptor signaling in the hypothalamic-pituitary-ovarian axis leads to ovarian epithelial tumorigenesis in mice. PLoS Genet. 2014;10:e1004230 pubmed 出版商
Shamir E, Pappalardo E, Jorgens D, Coutinho K, Tsai W, Aziz K, et al. Twist1-induced dissemination preserves epithelial identity and requires E-cadherin. J Cell Biol. 2014;204:839-56 pubmed 出版商
Lesniak D, Marshall K, Wellnitz S, Jenkins B, Baba Y, Rasband M, et al. Computation identifies structural features that govern neuronal firing properties in slowly adapting touch receptors. elife. 2014;3:e01488 pubmed 出版商
Chang T, Kunasegaran K, Tarulli G, De Silva D, Voorhoeve P, Pietersen A. New insights into lineage restriction of mammary gland epithelium using parity-identified mammary epithelial cells. Breast Cancer Res. 2014;16:R1 pubmed 出版商
Osada M, Singh V, Wu K, Sant Angelo D, Pezzano M. Label retention identifies a multipotent mesenchymal stem cell-like population in the postnatal thymus. PLoS ONE. 2013;8:e83024 pubmed 出版商
Kaanta A, Virtanen C, Selfors L, Brugge J, Neel B. Evidence for a multipotent mammary progenitor with pregnancy-specific activity. Breast Cancer Res. 2013;15:R65 pubmed
Hughes M, Jiang T, Lin S, Leung Y, Kobielak K, Widelitz R, et al. Disrupted ectodermal organ morphogenesis in mice with a conditional histone deacetylase 1, 2 deletion in the epidermis. J Invest Dermatol. 2014;134:24-32 pubmed 出版商
Sandilands A, Smith F, Lunny D, Campbell L, Davidson K, MacCallum S, et al. Generation and characterisation of keratin 7 (K7) knockout mice. PLoS ONE. 2013;8:e64404 pubmed 出版商
Leung A, Kent Morest D, Li J. Differential BMP signaling controls formation and differentiation of multipotent preplacodal ectoderm progenitors from human embryonic stem cells. Dev Biol. 2013;379:208-20 pubmed 出版商
Snider N, Leonard J, Kwan R, Griggs N, Rui L, Omary M. Glucose and SIRT2 reciprocally mediate the regulation of keratin 8 by lysine acetylation. J Cell Biol. 2013;200:241-7 pubmed 出版商
Forsman C, Ng B, Heinze R, Kuo C, Sergi C, Gopalakrishnan R, et al. BMP-binding protein twisted gastrulation is required in mammary gland epithelium for normal ductal elongation and myoepithelial compartmentalization. Dev Biol. 2013;373:95-106 pubmed 出版商
Huang C, Orvis G, Wang Y, Behringer R. Stromal-to-epithelial transition during postpartum endometrial regeneration. PLoS ONE. 2012;7:e44285 pubmed 出版商
Diaz Guerra E, Lillo M, Santamaría S, Garcia Sanz J. Intrinsic cues and hormones control mouse mammary epithelial tree size. FASEB J. 2012;26:3844-53 pubmed 出版商
Mashukova A, Forteza R, Wald F, SALAS P. PDK1 in apical signaling endosomes participates in the rescue of the polarity complex atypical PKC by intermediate filaments in intestinal epithelia. Mol Biol Cell. 2012;23:1664-74 pubmed 出版商
Kim S, Roopra A, Alexander C. A phenotypic mouse model of basaloid breast tumors. PLoS ONE. 2012;7:e30979 pubmed 出版商
Schneckenleithner C, Bago Horvath Z, Dolznig H, Neugebauer N, Kollmann K, Kolbe T, et al. Putting the brakes on mammary tumorigenesis: loss of STAT1 predisposes to intraepithelial neoplasias. Oncotarget. 2011;2:1043-54 pubmed
Riggio M, Polo M, Blaustein M, Colman Lerner A, Lüthy I, Lanari C, et al. PI3K/AKT pathway regulates phosphorylation of steroid receptors, hormone independence and tumor differentiation in breast cancer. Carcinogenesis. 2012;33:509-18 pubmed 出版商
Snider N, Weerasinghe S, Singla A, Leonard J, Hanada S, Andrews P, et al. Energy determinants GAPDH and NDPK act as genetic modifiers for hepatocyte inclusion formation. J Cell Biol. 2011;195:217-29 pubmed 出版商
Kim S, Goel S, Alexander C. Differentiation generates paracrine cell pairs that maintain basaloid mouse mammary tumors: proof of concept. PLoS ONE. 2011;6:e19310 pubmed 出版商
Harrison T, Smith Adams L, Moore P, Perna M, Sword J, Defoe D. Accelerated turnover of taste bud cells in mice deficient for the cyclin-dependent kinase inhibitor p27Kip1. BMC Neurosci. 2011;12:34 pubmed 出版商
Shaffer M, Huang Y, Corbo E, Wu G, Velez M, Choi J, et al. Ezrin is highly expressed in early thymocytes, but dispensable for T cell development in mice. PLoS ONE. 2010;5:e12404 pubmed 出版商
Sakamoto K, Triplett A, Schuler L, Wagner K. Janus kinase 2 is required for the initiation but not maintenance of prolactin-induced mammary cancer. Oncogene. 2010;29:5359-69 pubmed 出版商
Osada M, Jardine L, Misir R, Andl T, Millar S, Pezzano M. DKK1 mediated inhibition of Wnt signaling in postnatal mice leads to loss of TEC progenitors and thymic degeneration. PLoS ONE. 2010;5:e9062 pubmed 出版商
Sun P, Yuan Y, Li A, Li B, Dai X. Cytokeratin expression during mouse embryonic and early postnatal mammary gland development. Histochem Cell Biol. 2010;133:213-21 pubmed 出版商
Badders N, Goel S, Clark R, Klos K, Kim S, Bafico A, et al. The Wnt receptor, Lrp5, is expressed by mouse mammary stem cells and is required to maintain the basal lineage. PLoS ONE. 2009;4:e6594 pubmed 出版商
Shimono Y, Zabala M, Cho R, Lobo N, Dalerba P, Qian D, et al. Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell. 2009;138:592-603 pubmed 出版商
Krejci J, Uhlírová R, Galiova G, Kozubek S, Smigová J, Bartova E. Genome-wide reduction in H3K9 acetylation during human embryonic stem cell differentiation. J Cell Physiol. 2009;219:677-87 pubmed 出版商
Bryja V, Pachernik J, Vondracek J, Soucek K, Cajanek L, Horvath V, et al. Lineage specific composition of cyclin D-CDK4/CDK6-p27 complexes reveals distinct functions of CDK4, CDK6 and individual D-type cyclins in differentiating cells of embryonic origin. Cell Prolif. 2008;41:875-893 pubmed 出版商
Bartova E, Galiova G, Krejci J, Harnicarová A, Strasak L, Kozubek S. Epigenome and chromatin structure in human embryonic stem cells undergoing differentiation. Dev Dyn. 2008;237:3690-702 pubmed 出版商
Zhang W, Zhao J, Chen L, Urbanowicz M, Nagasaki T. Abnormal epithelial homeostasis in the cornea of mice with a destrin deletion. Mol Vis. 2008;14:1929-39 pubmed
Hozumi K, Mailhos C, Negishi N, Hirano K, Yahata T, Ando K, et al. Delta-like 4 is indispensable in thymic environment specific for T cell development. J Exp Med. 2008;205:2507-13 pubmed 出版商
Popa I, Zubkova I, Medvedovic M, Romantseva T, Mostowski H, Boyd R, et al. Regeneration of the adult thymus is preceded by the expansion of K5+K8+ epithelial cell progenitors and by increased expression of Trp63, cMyc and Tcf3 transcription factors in the thymic stroma. Int Immunol. 2007;19:1249-60 pubmed
Bryja V, Cajanek L, Pachernik J, Hall A, Horváth V, Dvorak P, et al. Abnormal development of mouse embryoid bodies lacking p27Kip1 cell cycle regulator. Stem Cells. 2005;23:965-74 pubmed
Pachernik J, Bryja V, Esner M, Kubala L, Dvorak P, Hampl A. Neural differentiation of pluripotent mouse embryonal carcinoma cells by retinoic acid: inhibitory effect of serum. Physiol Res. 2005;54:115-22 pubmed
Almholt K, Lund L, Rygaard J, Nielsen B, Danø K, Rømer J, et al. Reduced metastasis of transgenic mammary cancer in urokinase-deficient mice. Int J Cancer. 2005;113:525-32 pubmed
Bryja V, Pachernik J, Soucek K, Horvath V, Dvorak P, Hampl A. Increased apoptosis in differentiating p27-deficient mouse embryonic stem cells. Cell Mol Life Sci. 2004;61:1384-400 pubmed
Toivola D, Krishnan S, Binder H, Singh S, Omary M. Keratins modulate colonocyte electrolyte transport via protein mistargeting. J Cell Biol. 2004;164:911-21 pubmed
Szeder V, Grim M, Halata Z, Sieber Blum M. Neural crest origin of mammalian Merkel cells. Dev Biol. 2003;253:258-63 pubmed
Pérez Martínez C, García Fernández R, Ferreras Estrada M, Escudero Diez A, Espinosa Alvarez J, García Iglesias M. Optimization of the immunohistochemical demonstration of keratins in paraffin wax-embedded mouse skin. J Comp Pathol. 1998;119:177-81 pubmed
Laoide B, Courty Y, Gastinne I, Thibaut C, Kellermann O, Rougeon F. Immortalised mouse submandibular epithelial cell lines retain polarised structural and functional properties. J Cell Sci. 1996;109 ( Pt 12):2789-800 pubmed
Brulet P, Babinet C, Kemler R, Jacob F. Monoclonal antibodies against trophectoderm-specific markers during mouse blastocyst formation. Proc Natl Acad Sci U S A. 1980;77:4113-7 pubmed
Darmon M, Delescluse C, Semat A, Bernard B, Bailly J, Prunieras M. A keratin of fetal skin is reexpressed in human keratinocytes transformed by SV40 virus or treated with the tumor promoter TPA. Exp Cell Res. 1984;154:315-9 pubmed
Kemler R, Brulet P, Schnebelen M, Gaillard J, Jacob F. Reactivity of monoclonal antibodies against intermediate filament proteins during embryonic development. J Embryol Exp Morphol. 1981;64:45-60 pubmed
产品信息
内部号码 :
1388
名称 :
TROMA-I
Depositor Name :
Brulet, P. / Kemler, R.
Depositor Institution :
Institut Pasteur
Date Deposited :
2/13/87
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
抗原 :
角蛋白, 类型II/角蛋白8
抗原物种 :
小鼠
宿主物种 :
大鼠
抗体亚型 :
RIgG2a, kappa light chain
Isotype for catalog (legacy) :
IgG2a, kappa light chain
Positive Tested Species Reactivity :
人类, 小鼠
Species Tested (legacy) :
小鼠, 人类
Initial Publication Pubmed ID :
6933460
Depositor Notes (Special Instructions) :
The TROMA-I antibody is also known as EndoA.
Collections :
细胞标记, 细胞骨架, 人类
搜索关键词 :
Brulet, Philippe / Kemler, Rolf, Keratin, type II cytoskeletal 8; Cytokeratin end A, Mouse, RIgG2a, kappa light chain, Mouse/Human, Krt8, krt2-8, AB_531826, Monoclonal, cytokeratin 8, Endo-A, endoA
抗原分子量 :
Predicted: 54.5 kDa
基因 :
Krt8
Alternate Gene Name(s) :
krt2-8
UniProt数据库编号 :
P11679
抗体登记处号码 :
AB_531826
免疫原 :
TDM1 (Trophoblastoma) cell line intermediate filaments
免疫原序列 :
全长蛋白
克隆性 :
单克隆
Myeloma Strain :
SP2/0
表位定位 :
No
Recommended Applications :
流式细胞仪, FFPE, 免疫荧光, 免疫组化, 免疫沉淀, 免疫印迹
Immunoblotting (legacy) :
Yes
免疫组化PubMed IDs :
22683848 9749362 12645929 15472905 19665978 24603706 22180571 30611295 31391455 31444329
免疫荧光PubMed IDs :
19040567 15941856 23643939 6171607 6205890 9013327 29162901 26901525 29335337 29701767 27117404 26900150 30385780 31303547
免疫印迹PubMed IDs :
15941856 19202556 18985715 15717849 15170516 6205890
FFPE PubMed IDs :
15941856 9749362 12645929 15472905 19665978 24603706 31391455
流式细胞仪PubMed IDs :
17823311
PubMed IDs :
25083987 22180571
其他信息 :
工作在石蜡;识别角蛋白8;
DSHB增长培养基 :
Iscove's
References (legacy) :
Proc. Nat'l. Acad. Sci. 77, 4113-4117.; J. Embryol. Exp. Morph. 64, 45-60.; Exp. Cell Res. 154(1), 315-319.; J. Cell Sci. 109, 2789-2800.; J. Comp. Path. 119, 177-181.; Dev. Biol. 253, 258-263.; Int. J. Cancer 113, 525-532.; Cell 138, 592-603.; PLoS Genet 10(3): doi:10.1371/journal.pgen.1004230.; J. Clin. Invest. doi:10.1172/JCI66603.
公司信息
Developmental Studies Hybridoma Bank
University of Iowa
dshb@uiowa.edu
http://dshb.biology.uiowa.edu
公司总部: 美国
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构,为生命科学研究领域及诊断领域,提供高质量的抗体等产品。