| 出版应用/物种/样本/稀释 | 参考文献 |
|---|
| Molina L, Zhu J, Li Q, Pradhan Sundd T, Krutsenko Y, Sayed K, et al. Compensatory hepatic adaptation accompanies permanent absence of intrahepatic biliary network due to YAP1 loss in liver progenitors. Cell Rep. 2021;36:109310 pubmed 出版商 |
| Pocaterra A, Scattolin G, Romani P, Ament C, Ribback S, Chen X, et al. Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development. Commun Biol. 2021;4:763 pubmed 出版商 |
- 免疫细胞化学; 小鼠; 图 7d
- 免疫组化; 小鼠; 1:100; 图 6i
| Kemp S, Carpenter E, Steele N, Donahue K, Nwosu Z, Pacheco A, et al. Apolipoprotein E Promotes Immune Suppression in Pancreatic Cancer through NF-κB-Mediated Production of CXCL1. Cancer Res. 2021;81:4305-4318 pubmed 出版商 |
| Flowers B, Xu H, Mulligan A, Hanson K, Seoane J, Vogel H, et al. Cell of Origin Influences Pancreatic Cancer Subtype. Cancer Discov. 2021;11:660-677 pubmed 出版商 |
- 免疫组化; 人类; 图 5f
- 免疫组化; 小鼠; 图 5f
| Hendley A, Rao A, Leonhardt L, Ashe S, Smith J, Giacometti S, et al. Single-cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal tree. elife. 2021;10: pubmed 出版商 |
- 免疫组化-石蜡切片; 小鼠; 1:1000; 图 1f
| Hsieh M, Weng C, Lin Y, Wu C, Chen L, Cheng K. Inhibition of β-Catenin Activity Abolishes LKB1 Loss-Driven Pancreatic Cystadenoma in Mice. Int J Mol Sci. 2021;22: pubmed 出版商 |
- 免疫组化-石蜡切片; 小鼠; 1:50; 图 2b
| Hankeova S, Salplachta J, Zikmund T, Kavkova M, Van Hul N, Brinek A, et al. DUCT reveals architectural mechanisms contributing to bile duct recovery in a mouse model for Alagille syndrome. elife. 2021;10: pubmed 出版商 |
- 免疫组化-冰冻切片; 人类; 1:100; 图 s12b
- 免疫细胞化学; 人类; 1:100; 图 1c
| Sampaziotis F, Muraro D, Tysoe O, Sawiak S, Beach T, Godfrey E, et al. Cholangiocyte organoids can repair bile ducts after transplantation in the human liver. Science. 2021;371:839-846 pubmed 出版商 |
| Prior N, Hindley C, Rost F, Meléndez E, Lau W, Gottgens B, et al. Lgr5+ stem and progenitor cells reside at the apex of a heterogeneous embryonic hepatoblast pool. Development. 2019;146: pubmed 出版商 |
- 免疫组化-石蜡切片; 小鼠; 图 1d
- 免疫印迹; 小鼠; 图 4c
| Krishna Subramanian S, Singer S, Armaka M, Banales J, Hölzer K, Schirmacher P, et al. RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury. Cell Death Differ. 2019;: pubmed 出版商 |
| Gorth D, Shapiro I, Risbud M. Transgenic mice overexpressing human TNF-α experience early onset spontaneous intervertebral disc herniation in the absence of overt degeneration. Cell Death Dis. 2018;10:7 pubmed 出版商 |
| He P, Yang J, Yang V, Bialkowska A. Krüppel-like Factor 5, Increased in Pancreatic Ductal Adenocarcinoma, Promotes Proliferation, Acinar-to-Ductal Metaplasia, Pancreatic Intraepithelial Neoplasia, and Tumor Growth in Mice. Gastroenterology. 2018;154:1494-1508.e13 pubmed 出版商 |
- 免疫组化-石蜡切片; 小鼠; 1:200; 图 1d
| Mello S, Valente L, Raj N, Seoane J, Flowers B, McClendon J, et al. A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer. Cancer Cell. 2017;32:460-473.e6 pubmed 出版商 |
| Van T, Polykratis A, Straub B, Kondylis V, Papadopoulou N, Pasparakis M. Kinase-independent functions of RIPK1 regulate hepatocyte survival and liver carcinogenesis. J Clin Invest. 2017;127:2662-2677 pubmed 出版商 |
| Daley D, Mani V, Mohan N, Akkad N, Pandian G, Savadkar S, et al. NLRP3 signaling drives macrophage-induced adaptive immune suppression in pancreatic carcinoma. J Exp Med. 2017;214:1711-1724 pubmed 出版商 |
| Halbrook C, Wen H, Ruggeri J, Takeuchi K, Zhang Y, di Magliano M, et al. Mitogen-activated Protein Kinase Kinase Activity Maintains Acinar-to-Ductal Metaplasia and Is Required for Organ Regeneration in Pancreatitis. Cell Mol Gastroenterol Hepatol. 2017;3:99-118 pubmed 出版商 |
- 免疫组化-冰冻切片; 小鼠; 1:100; 图 1d
| Pu W, Zhang H, Huang X, Tian X, He L, Wang Y, et al. Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration. Nat Commun. 2016;7:13369 pubmed 出版商 |
| Li Q, Wang H, Zogopoulos G, Shao Q, Dong K, Lv F, et al. Reg proteins promote acinar-to-ductal metaplasia and act as novel diagnostic and prognostic markers in pancreatic ductal adenocarcinoma. Oncotarget. 2016;7:77838-77853 pubmed 出版商 |
| Zhang Y, Velez Delgado A, Mathew E, Li D, Mendez F, Flannagan K, et al. Myeloid cells are required for PD-1/PD-L1 checkpoint activation and the establishment of an immunosuppressive environment in pancreatic cancer. Gut. 2017;66:124-136 pubmed 出版商 |
| Hintermann E, Bayer M, Ehser J, Aurrand Lions M, Pfeilschifter J, Imhof B, et al. Murine junctional adhesion molecules JAM-B and JAM-C mediate endothelial and stellate cell interactions during hepatic fibrosis. Cell Adh Migr. 2016;10:419-33 pubmed 出版商 |
| Waisbourd Zinman O, Koh H, Tsai S, Lavrut P, Dang C, Zhao X, et al. The toxin biliatresone causes mouse extrahepatic cholangiocyte damage and fibrosis through decreased glutathione and SOX17. Hepatology. 2016;64:880-93 pubmed 出版商 |
| Seifert L, Werba G, Tiwari S, Giao Ly N, Nguy S, Alothman S, et al. Radiation Therapy Induces Macrophages to Suppress T-Cell Responses Against Pancreatic Tumors in Mice. Gastroenterology. 2016;150:1659-1672.e5 pubmed 出版商 |
- 免疫组化-石蜡切片; 小鼠; 1:100; 图 s2
| Diersch S, Wirth M, Schneeweis C, Jörs S, Geisler F, Siveke J, et al. Kras(G12D) induces EGFR-MYC cross signaling in murine primary pancreatic ductal epithelial cells. Oncogene. 2016;35:3880-6 pubmed 出版商 |
| Pajoohesh Ganji A, Pal Ghosh S, Tadvalkar G, Stepp M. K14 + compound niches are present on the mouse cornea early after birth and expand after debridement wounds. Dev Dyn. 2016;245:132-43 pubmed 出版商 |
- 免疫组化-石蜡切片; 人类; 图 4
- 免疫组化-石蜡切片; 小鼠; 图 4
| Finkin S, Yuan D, Stein I, Taniguchi K, Weber A, Unger K, et al. Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma. Nat Immunol. 2015;16:1235-44 pubmed 出版商 |
- 免疫组化-石蜡切片; 小鼠; 1:500; 图 s5e
| Mazur P, Herner A, Mello S, Wirth M, Hausmann S, Sánchez Rivera F, et al. Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma. Nat Med. 2015;21:1163-71 pubmed 出版商 |
| Chiou S, Winters I, Wang J, Naranjo S, Dudgeon C, Tamburini F, et al. Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing. Genes Dev. 2015;29:1576-85 pubmed 出版商 |
| Li X, Tao J, Cigliano A, Sini M, Calderaro J, Azoulay D, et al. Co-activation of PIK3CA and Yap promotes development of hepatocellular and cholangiocellular tumors in mouse and human liver. Oncotarget. 2015;6:10102-15 pubmed |
| Lee J, Garbe J, Vrba L, Miyano M, Futscher B, Stampfer M, et al. Age and the means of bypassing stasis influence the intrinsic subtype of immortalized human mammary epithelial cells. Front Cell Dev Biol. 2015;3:13 pubmed 出版商 |
| Wögenstein K, Szabo S, Lunova M, Wiche G, Haybaeck J, Strnad P, et al. Epiplakin deficiency aggravates murine caerulein-induced acute pancreatitis and favors the formation of acinar keratin granules. PLoS ONE. 2014;9:e108323 pubmed 出版商 |
| Morris S, Carter K, Baek J, Koszarek A, Yeh M, Knoblaugh S, et al. TGF-? signaling alters the pattern of liver tumorigenesis induced by Pten inactivation. Oncogene. 2015;34:3273-82 pubmed 出版商 |
| Ehlken H, Krishna Subramanian S, Ochoa Callejero L, Kondylis V, Nadi N, Straub B, et al. Death receptor-independent FADD signalling triggers hepatitis and hepatocellular carcinoma in mice with liver parenchymal cell-specific NEMO knockout. Cell Death Differ. 2014;21:1721-32 pubmed 出版商 |
- 免疫组化-石蜡切片; 小鼠; 1:400; 图 7
| Karaca G, Swiderska Syn M, Xie G, Syn W, Krüger L, Machado M, et al. TWEAK/Fn14 signaling is required for liver regeneration after partial hepatectomy in mice. PLoS ONE. 2014;9:e83987 pubmed 出版商 |
| Chan I, Guy C, Machado M, Wank A, Kadiyala V, Michelotti G, et al. Alcohol activates the hedgehog pathway and induces related procarcinogenic processes in the alcohol-preferring rat model of hepatocarcinogenesis. Alcohol Clin Exp Res. 2014;38:787-800 pubmed 出版商 |
| Reichert M, Takano S, von Burstin J, Kim S, Lee J, Ihida Stansbury K, et al. The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis. Genes Dev. 2013;27:288-300 pubmed 出版商 |
| Carrasco M, Delgado I, Soria B, Martin F, Rojas A. GATA4 and GATA6 control mouse pancreas organogenesis. J Clin Invest. 2012;122:3504-15 pubmed 出版商 |
| Morris J, Yashinskie J, Koche R, Chandwani R, Tian S, Chen C, et al. α-Ketoglutarate links p53 to cell fate during tumour suppression. Nature. 2019;573:595-599 pubmed 出版商 |
| Yamaguchi T, Ikehara S, Akimoto Y, Nakanishi H, Kume M, Yamamoto K, et al. TGF-β signaling promotes tube-structure-forming growth in pancreatic duct adenocarcinoma. Sci Rep. 2019;9:11247 pubmed 出版商 |
| Liu Y, Kim H, Dong E, Dong C, Huang M, Liu Y, et al. Sesn3 deficiency promotes carcinogen-induced hepatocellular carcinoma via regulation of the hedgehog pathway. Biochim Biophys Acta Mol Basis Dis. 2019;1865:2685-2693 pubmed 出版商 |
| Mohanty S, Pinelli R, Pricop P, Albert T, Dahia C. Chondrocyte-like nested cells in the aged intervertebral disc are late-stage nucleus pulposus cells. Aging Cell. 2019;18:e13006 pubmed 出版商 |
| Perkhofer L, Engler M, Gout J, Arnold F, Morawe M, Breunig M, et al. Pancreatic Ductal Organoids React Kras Dependent to the Removal of Tumor Suppressive Roadblocks. Stem Cells Int. 2019;2019:2079742 pubmed 出版商 |
| Pocaterra A, Santinon G, Romani P, Brian I, Dimitracopoulos A, Ghisleni A, et al. F-actin dynamics regulates mammalian organ growth and cell fate maintenance. J Hepatol. 2019;71:130-142 pubmed 出版商 |
| Rubio Tomás T, Aguilar Bravo B, Sancho Bru P. Genetic Lineage Tracing of Biliary Epithelial Cells. Methods Mol Biol. 2019;1905:45-57 pubmed 出版商 |
| Goehrig D, Nigri J, Samain R, Wu Z, Cappello P, Gabiane G, et al. Stromal protein βig-h3 reprogrammes tumour microenvironment in pancreatic cancer. Gut. 2019;68:693-707 pubmed 出版商 |
| Debray D, El Mourabit H, Merabtene F, Brot L, Ulveling D, Chretien Y, et al. Diet-Induced Dysbiosis and Genetic Background Synergize With Cystic Fibrosis Transmembrane Conductance Regulator Deficiency to Promote Cholangiopathy in Mice. Hepatol Commun. 2018;2:1533-1549 pubmed 出版商 |
| Zhang R, Zeng X, Lin Z, Ming Fu -, Tong Y, Lui V, et al. Downregulation of Hes1 expression in experimental biliary atresia and its effects on bile duct structure. World J Gastroenterol. 2018;24:3260-3272 pubmed 出版商 |
| Livshits G, Alonso Curbelo D, Morris J, Koche R, Saborowski M, Wilkinson J, et al. Arid1a restrains Kras-dependent changes in acinar cell identity. elife. 2018;7: pubmed 出版商 |
| Zubeldia Plazaola A, Recalde Percaz L, Moragas N, Alcaraz M, Chen X, Mancino M, et al. Glucocorticoids promote transition of ductal carcinoma in situ to invasive ductal carcinoma by inducing myoepithelial cell apoptosis. Breast Cancer Res. 2018;20:65 pubmed 出版商 |
| Pelissier Vatter F, Schapiro D, Chang H, Borowsky A, Lee J, Parvin B, et al. High-Dimensional Phenotyping Identifies Age-Emergent Cells in Human Mammary Epithelia. Cell Rep. 2018;23:1205-1219 pubmed 出版商 |
| Silagi E, Batista P, Shapiro I, Risbud M. Expression of Carbonic Anhydrase III, a Nucleus Pulposus Phenotypic Marker, is Hypoxia-responsive and Confers Protection from Oxidative Stress-induced Cell Death. Sci Rep. 2018;8:4856 pubmed 出版商 |
| Hernandez C, Huebener P, Pradere J, Antoine D, Friedman R, Schwabe R. HMGB1 links chronic liver injury to progenitor responses and hepatocarcinogenesis. J Clin Invest. 2018;128:2436-2451 pubmed 出版商 |
| Morell C, Fiorotto R, Meroni M, Raizner A, Torsello B, Cadamuro M, et al. Notch signaling and progenitor/ductular reaction in steatohepatitis. PLoS ONE. 2017;12:e0187384 pubmed 出版商 |
| Gonzalez Rodriguez A, Valdecantos M, Rada P, Addante A, Barahona I, Rey E, et al. Dual role of protein tyrosine phosphatase 1B in the progression and reversion of non-alcoholic steatohepatitis. Mol Metab. 2018;7:132-146 pubmed 出版商 |
| Ferreira R, Sancho R, Messal H, Nye E, Spencer Dene B, Stone R, et al. Duct- and Acinar-Derived Pancreatic Ductal Adenocarcinomas Show Distinct Tumor Progression and Marker Expression. Cell Rep. 2017;21:966-978 pubmed 出版商 |
| Chen F, Lee A, Ge S, Nathan S, Knox S, McNamara N. Aire-deficient mice provide a model of corneal and lacrimal gland neuropathy in Sjögren's syndrome. PLoS ONE. 2017;12:e0184916 pubmed 出版商 |
| Lavoie E, Fausther M, Goree J, Dranoff J. The Cholangiocyte Adenosine-IL-6 Axis Regulates Survival During Biliary Cirrhosis. Gene Expr. 2017;17:327-340 pubmed 出版商 |
| Tu Q, Hao J, Zhou X, Yan L, Dai H, Sun B, et al. CDKN2B deletion is essential for pancreatic cancer development instead of unmeaningful co-deletion due to juxtaposition to CDKN2A. Oncogene. 2018;37:128-138 pubmed 出版商 |
| Zhao M, Rabieifar P, Costa T, Zhuang T, Minden A, Lohr M, et al. Pdx1-Cre-driven conditional gene depletion suggests PAK4 as dispensable for mouse pancreas development. Sci Rep. 2017;7:7031 pubmed 出版商 |
| Emmerson E, May A, Nathan S, Cruz Pacheco N, Lizama C, Maliskova L, et al. SOX2 regulates acinar cell development in the salivary gland. elife. 2017;6: pubmed 出版商 |
| Wu N, Nguyen Q, Wan Y, Zhou T, Venter J, Frampton G, et al. The Hippo signaling functions through the Notch signaling to regulate intrahepatic bile duct development in mammals. Lab Invest. 2017;97:843-853 pubmed 出版商 |
| Naiman N, Fujioka K, Fujino M, Valerius M, Potter S, McMahon A, et al. Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development. Dev Cell. 2017;41:349-365.e3 pubmed 出版商 |
| ElMokh O, Ruffieux Daidié D, Roelli M, Stooss A, Phillips W, Gertsch J, et al. Combined MEK and Pi3'-kinase inhibition reveals synergy in targeting thyroid cancer in vitro and in vivo. Oncotarget. 2017;8:24604-24620 pubmed 出版商 |
| Rókusz A, Veres D, Szücs A, Bugyik E, Mózes M, Paku S, et al. Ductular reaction correlates with fibrogenesis but does not contribute to liver regeneration in experimental fibrosis models. PLoS ONE. 2017;12:e0176518 pubmed 出版商 |
| Yagai T, Matsui S, Harada K, Inagaki F, Saijou E, Miura Y, et al. Expression and localization of sterile alpha motif domain containing 5 is associated with cell type and malignancy of biliary tree. PLoS ONE. 2017;12:e0175355 pubmed 出版商 |
| Wang Y, Huang X, He L, Pu W, Li Y, Liu Q, et al. Genetic tracing of hepatocytes in liver homeostasis, injury, and regeneration. J Biol Chem. 2017;292:8594-8604 pubmed 出版商 |
| Ohlund D, Handly Santana A, Biffi G, Elyada E, Almeida A, Ponz Sarvisé M, et al. Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer. J Exp Med. 2017;214:579-596 pubmed 出版商 |
| Coate K, Hernandez G, Thorne C, Sun S, Le T, Vale K, et al. FGF21 Is an Exocrine Pancreas Secretagogue. Cell Metab. 2017;25:472-480 pubmed 出版商 |
| Maroni L, Agostinelli L, Saccomanno S, Pinto C, Giordano D, Rychlicki C, et al. Nlrp3 Activation Induces Il-18 Synthesis and Affects the Epithelial Barrier Function in Reactive Cholangiocytes. Am J Pathol. 2017;187:366-376 pubmed 出版商 |
| Lemberger U, Fuchs C, Karer M, Haas S, Stojakovic T, Schöfer C, et al. Hepatocyte specific expression of an oncogenic variant of β-catenin results in cholestatic liver disease. Oncotarget. 2016;7:86985-86998 pubmed 出版商 |
| Verhulst S, Best J, Syn W, Reynaert H, Hellemans K, Canbay A, et al. Infliximab and Dexamethasone Attenuate the Ductular Reaction in Mice. Sci Rep. 2016;6:36586 pubmed 出版商 |
| Kottakis F, Nicolay B, Roumane A, Karnik R, Gu H, Nagle J, et al. LKB1 loss links serine metabolism to DNA methylation and tumorigenesis. Nature. 2016;539:390-395 pubmed 出版商 |
| Pitarresi J, Liu X, Sharma S, Cuitino M, Kladney R, Mace T, et al. Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia. Neoplasia. 2016;18:541-52 pubmed 出版商 |
| Liu X, Pitarresi J, Cuitino M, Kladney R, Woelke S, Sizemore G, et al. Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia. Genes Dev. 2016;30:1943-55 pubmed 出版商 |
| Helenius T, Antman C, Asghar M, Nyström J, Toivola D. Keratins Are Altered in Intestinal Disease-Related Stress Responses. Cells. 2016;5: pubmed 出版商 |
| Best J, Verhulst S, Syn W, Lagaisse K, Van Hul N, Heindryckx F, et al. Macrophage Depletion Attenuates Extracellular Matrix Deposition and Ductular Reaction in a Mouse Model of Chronic Cholangiopathies. PLoS ONE. 2016;11:e0162286 pubmed 出版商 |
| Miyazaki S, Tashiro F, Miyazaki J. Transgenic Expression of a Single Transcription Factor Pdx1 Induces Transdifferentiation of Pancreatic Acinar Cells to Endocrine Cells in Adult Mice. PLoS ONE. 2016;11:e0161190 pubmed 出版商 |
| Lee D, Park J, Kim T, Kim S, Kim T, Kim M, et al. LATS-YAP/TAZ controls lineage specification by regulating TGF? signaling and Hnf4? expression during liver development. Nat Commun. 2016;7:11961 pubmed 出版商 |
| Thompson M, Cismowski M, Trask A, Lallier S, Graf A, Rogers L, et al. Enhanced Steatosis and Fibrosis in Liver of Adult Offspring Exposed to Maternal High-Fat Diet. Gene Expr. 2016;17:47-59 pubmed 出版商 |
| Köhn Gaone J, Dwyer B, Grzelak C, Miller G, Shackel N, Ramm G, et al. Divergent Inflammatory, Fibrogenic, and Liver Progenitor Cell Dynamics in Two Common Mouse Models of Chronic Liver Injury. Am J Pathol. 2016;186:1762-1774 pubmed 出版商 |
| Reynoird N, Mazur P, Stellfeld T, Flores N, Lofgren S, Carlson S, et al. Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer. Genes Dev. 2016;30:772-85 pubmed 出版商 |
| Spirli C, Villani A, Mariotti V, Fabris L, Fiorotto R, Strazzabosco M. Posttranslational regulation of polycystin-2 protein expression as a novel mechanism of cholangiocyte reaction and repair from biliary damage. Hepatology. 2015;62:1828-39 pubmed 出版商 |
| Font Burgada J, Shalapour S, Ramaswamy S, Hsueh B, Rossell D, Umemura A, et al. Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer. Cell. 2015;162:766-79 pubmed 出版商 |
| Marti P, Stein C, Blumer T, Abraham Y, Dill M, Pikiolek M, et al. YAP promotes proliferation, chemoresistance, and angiogenesis in human cholangiocarcinoma through TEAD transcription factors. Hepatology. 2015;62:1497-510 pubmed 出版商 |
| Sawai Y, Kodama Y, Shimizu T, Ota Y, Maruno T, Eso Y, et al. Activation-Induced Cytidine Deaminase Contributes to Pancreatic Tumorigenesis by Inducing Tumor-Related Gene Mutations. Cancer Res. 2015;75:3292-301 pubmed 出版商 |
| Zubeldia Plazaola A, Ametller E, Mancino M, Prats de Puig M, López Plana A, Guzmán F, et al. Comparison of methods for the isolation of human breast epithelial and myoepithelial cells. Front Cell Dev Biol. 2015;3:32 pubmed 出版商 |
| Asghar M, Silvander J, Helenius T, Lähdeniemi I, Alam C, Fortelius L, et al. The amount of keratins matters for stress protection of the colonic epithelium. PLoS ONE. 2015;10:e0127436 pubmed 出版商 |
| Minuth W, Denk L. Detection of abnormal extracellular matrix in the interstitium of regenerating renal tubules. Int J Mol Sci. 2014;15:23240-54 pubmed 出版商 |
| Falix F, Weeda V, Labruyere W, Poncy A, de Waart D, Hakvoort T, et al. Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning. Dev Biol. 2014;396:201-13 pubmed 出版商 |
| Wu C, Carpenter E, Takeuchi K, Halbrook C, Peverley L, Bien H, et al. PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice. Gastroenterology. 2014;147:1405-16.e7 pubmed 出版商 |
| Nedvetsky P, Emmerson E, Finley J, Ettinger A, Cruz Pacheco N, Prochazka J, et al. Parasympathetic innervation regulates tubulogenesis in the developing salivary gland. Dev Cell. 2014;30:449-62 pubmed 出版商 |
| Criscimanna A, Coudriet G, Gittes G, Piganelli J, Esni F. Activated macrophages create lineage-specific microenvironments for pancreatic acinar- and ?-cell regeneration in mice. Gastroenterology. 2014;147:1106-18.e11 pubmed 出版商 |
| Minuth W, Denk L. Tannic acid label indicates abnormal cell development coinciding with regeneration of renal tubules. BMC Clin Pathol. 2014;14:34 pubmed 出版商 |
| Pelissier F, Garbe J, Ananthanarayanan B, Miyano M, Lin C, Jokela T, et al. Age-related dysfunction in mechanotransduction impairs differentiation of human mammary epithelial progenitors. Cell Rep. 2014;7:1926-39 pubmed 出版商 |
| Zhang Y, Yan W, Mathew E, Bednar F, Wan S, Collins M, et al. CD4+ T lymphocyte ablation prevents pancreatic carcinogenesis in mice. Cancer Immunol Res. 2014;2:423-35 pubmed 出版商 |
| Aksoy I, Giudice V, Delahaye E, Wianny F, Aubry M, Mure M, et al. Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells. Nat Commun. 2014;5:3719 pubmed 出版商 |
| Davey M, McTeir L, Barrie A, Freem L, Stephen L. Loss of cilia causes embryonic lung hypoplasia, liver fibrosis, and cholestasis in the talpid3 ciliopathy mutant. Organogenesis. 2014;10:177-85 pubmed 出版商 |
| Mills L, Zhang L, Marler R, Svingen P, Fernández Barrena M, Dave M, et al. Inactivation of the transcription factor GLI1 accelerates pancreatic cancer progression. J Biol Chem. 2014;289:16516-25 pubmed 出版商 |
| Davies C, Harvey E, McMahon R, Finegan K, Connor F, Davis R, et al. Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma. Cancer Res. 2014;74:3344-56 pubmed 出版商 |
| Rodrigo Torres D, Affò S, Coll M, Morales Ibanez O, Millán C, Blaya D, et al. The biliary epithelium gives rise to liver progenitor cells. Hepatology. 2014;60:1367-77 pubmed 出版商 |
| Rielland M, Cantor D, Graveline R, Hajdu C, Mara L, Diaz B, et al. Senescence-associated SIN3B promotes inflammation and pancreatic cancer progression. J Clin Invest. 2014;124:2125-35 pubmed |
| Tsuchiya A, Lu W, Weinhold B, Boulter L, Stutchfield B, Williams M, et al. Polysialic acid/neural cell adhesion molecule modulates the formation of ductular reactions in liver injury. Hepatology. 2014;60:1727-40 pubmed 出版商 |
| Cai S, Mennone A, Soroka C, Boyer J. All-trans-retinoic acid improves cholestasis in α-naphthylisothiocyanate-treated rats and Mdr2-/- mice. J Pharmacol Exp Ther. 2014;349:94-8 pubmed 出版商 |
| Cai S, Mennone A, Soroka C, Boyer J. Altered expression and function of canalicular transporters during early development of cholestatic liver injury in Abcb4-deficient mice. Am J Physiol Gastrointest Liver Physiol. 2014;306:G670-6 pubmed 出版商 |
| Li A, Morton J, Ma Y, Karim S, Zhou Y, Faller W, et al. Fascin is regulated by slug, promotes progression of pancreatic cancer in mice, and is associated with patient outcomes. Gastroenterology. 2014;146:1386-96.e1-17 pubmed 出版商 |
| Underkoffler L, Carr E, Nelson A, Ryan M, Schulz R, Schultz R, et al. Microarray data reveal relationship between Jag1 and Ddr1 in mouse liver. PLoS ONE. 2013;8:e84383 pubmed 出版商 |
| Gore A, Deitz S, Palam L, Craven K, Korc M. Pancreatic cancer-associated retinoblastoma 1 dysfunction enables TGF-? to promote proliferation. J Clin Invest. 2014;124:338-52 pubmed 出版商 |
| Collins M, Yan W, Sebolt Leopold J, Pasca di Magliano M. MAPK signaling is required for dedifferentiation of acinar cells and development of pancreatic intraepithelial neoplasia in mice. Gastroenterology. 2014;146:822-834.e7 pubmed 出版商 |
| Torres M, Rachagani S, Souchek J, Mallya K, Johansson S, Batra S. Novel pancreatic cancer cell lines derived from genetically engineered mouse models of spontaneous pancreatic adenocarcinoma: applications in diagnosis and therapy. PLoS ONE. 2013;8:e80580 pubmed 出版商 |
| Mederacke I, Hsu C, Troeger J, Huebener P, Mu X, Dapito D, et al. Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology. Nat Commun. 2013;4:2823 pubmed 出版商 |
| Court H, Amoyel M, Hackman M, Lee K, Xu R, Miller G, et al. Isoprenylcysteine carboxylmethyltransferase deficiency exacerbates KRAS-driven pancreatic neoplasia via Notch suppression. J Clin Invest. 2013;123:4681-94 pubmed |
| Alam C, Silvander J, Daniel E, Tao G, Kvarnström S, Alam P, et al. Keratin 8 modulates ?-cell stress responses and normoglycaemia. J Cell Sci. 2013;126:5635-44 pubmed 出版商 |
| Zhang Y, Yan W, Collins M, Bednar F, Rakshit S, Zetter B, et al. Interleukin-6 is required for pancreatic cancer progression by promoting MAPK signaling activation and oxidative stress resistance. Cancer Res. 2013;73:6359-74 pubmed 出版商 |
| Ito S, Satoh J, Matsubara T, Shah Y, Ahn S, Anderson C, et al. Cholestasis induces reversible accumulation of periplakin in mouse liver. BMC Gastroenterol. 2013;13:116 pubmed 出版商 |
| Lin T, Ibrahim W, Peng C, Finegold M, Tsai R. A novel role of nucleostemin in maintaining the genome integrity of dividing hepatocytes during mouse liver development and regeneration. Hepatology. 2013;58:2176-87 pubmed 出版商 |
| Sandilands A, Smith F, Lunny D, Campbell L, Davidson K, MacCallum S, et al. Generation and characterisation of keratin 7 (K7) knockout mice. PLoS ONE. 2013;8:e64404 pubmed 出版商 |
| Sputova K, Garbe J, Pelissier F, Chang E, Stampfer M, Labarge M. Aging phenotypes in cultured normal human mammary epithelial cells are correlated with decreased telomerase activity independent of telomere length. Genome Integr. 2013;4:4 pubmed 出版商 |
| Nollevaux M, Rahier J, Marchandise J, Thurion P, Godecharles S, Van den Steen G, et al. Characterization of ?-cell plasticity mechanisms induced in mice by a transient source of exogenous insulin. Am J Physiol Endocrinol Metab. 2013;304:E711-23 pubmed 出版商 |
| Ray K, Moss M, Franklin J, Weaver C, Higginbotham J, Song Y, et al. Heparin-binding epidermal growth factor-like growth factor eliminates constraints on activated Kras to promote rapid onset of pancreatic neoplasia. Oncogene. 2014;33:823-31 pubmed 出版商 |
| Kenerson H, Yeh M, Kazami M, Jiang X, Riehle K, McIntyre R, et al. Akt and mTORC1 have different roles during liver tumorigenesis in mice. Gastroenterology. 2013;144:1055-65 pubmed 出版商 |
| Takase H, Itoh T, Ino S, Wang T, Koji T, Akira S, et al. FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration. Genes Dev. 2013;27:169-81 pubmed 出版商 |
| Collins M, Brisset J, Zhang Y, Bednar F, Pierre J, Heist K, et al. Metastatic pancreatic cancer is dependent on oncogenic Kras in mice. PLoS ONE. 2012;7:e49707 pubmed 出版商 |
| Miyazaki S, Tashiro F, Fujikura J, Yamato E, Miyazaki J. Acinar-to-ductal metaplasia induced by adenovirus-mediated pancreatic expression of Isl1. PLoS ONE. 2012;7:e47536 pubmed 出版商 |
| Kues W, Herrmann D, Barg Kues B, Haridoss S, Nowak Imialek M, Buchholz T, et al. Derivation and characterization of sleeping beauty transposon-mediated porcine induced pluripotent stem cells. Stem Cells Dev. 2013;22:124-35 pubmed 出版商 |
| Ardito C, Grüner B, Takeuchi K, Lubeseder Martellato C, Teichmann N, Mazur P, et al. EGF receptor is required for KRAS-induced pancreatic tumorigenesis. Cancer Cell. 2012;22:304-17 pubmed 出版商 |
| Li H, Kapoor A, Giel Moloney M, Rindi G, Leiter A. Notch signaling differentially regulates the cell fate of early endocrine precursor cells and their maturing descendants in the mouse pancreas and intestine. Dev Biol. 2012;371:156-69 pubmed 出版商 |
| Español Suñer R, Carpentier R, Van Hul N, Legry V, Achouri Y, Cordi S, et al. Liver progenitor cells yield functional hepatocytes in response to chronic liver injury in mice. Gastroenterology. 2012;143:1564-1575.e7 pubmed 出版商 |
| Bai H, Zhang N, Xu Y, Chen Q, Khan M, Potter J, et al. Yes-associated protein regulates the hepatic response after bile duct ligation. Hepatology. 2012;56:1097-107 pubmed 出版商 |
| Flisikowska T, Merkl C, Landmann M, Eser S, Rezaei N, Cui X, et al. A porcine model of familial adenomatous polyposis. Gastroenterology. 2012;143:1173-1175.e7 pubmed 出版商 |
| Coots A, Donnelly B, Mohanty S, McNeal M, Sestak K, Tiao G. Rotavirus infection of human cholangiocytes parallels the murine model of biliary atresia. J Surg Res. 2012;177:275-81 pubmed 出版商 |
| Grüner B, Hahne H, Mazur P, Trajkovic Arsic M, Maier S, Esposito I, et al. MALDI imaging mass spectrometry for in situ proteomic analysis of preneoplastic lesions in pancreatic cancer. PLoS ONE. 2012;7:e39424 pubmed 出版商 |
| Pylayeva Gupta Y, Lee K, Hajdu C, Miller G, Bar Sagi D. Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia. Cancer Cell. 2012;21:836-47 pubmed 出版商 |
| Dahia C, Mahoney E, Wylie C. Shh signaling from the nucleus pulposus is required for the postnatal growth and differentiation of the mouse intervertebral disc. PLoS ONE. 2012;7:e35944 pubmed 出版商 |
| Garbe J, Pepin F, Pelissier F, Sputova K, Fridriksdottir A, Guo D, et al. Accumulation of multipotent progenitors with a basal differentiation bias during aging of human mammary epithelia. Cancer Res. 2012;72:3687-701 pubmed 出版商 |
| Guo L, Sans M, Hou Y, Ernst S, Williams J. c-Jun/AP-1 is required for CCK-induced pancreatic acinar cell dedifferentiation and DNA synthesis in vitro. Am J Physiol Gastrointest Liver Physiol. 2012;302:G1381-96 pubmed 出版商 |
| Scotti M, Smith K, Butler A, Calcagno S, Crawford H, Leitges M, et al. Protein kinase C iota regulates pancreatic acinar-to-ductal metaplasia. PLoS ONE. 2012;7:e30509 pubmed 出版商 |
| Weerachayaphorn J, Mennone A, Soroka C, Harry K, Hagey L, Kensler T, et al. Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine. Am J Physiol Gastrointest Liver Physiol. 2012;302:G925-36 pubmed 出版商 |
| Gier B, Matveyenko A, Kirakossian D, Dawson D, Dry S, Butler P. Chronic GLP-1 receptor activation by exendin-4 induces expansion of pancreatic duct glands in rats and accelerates formation of dysplastic lesions and chronic pancreatitis in the Kras(G12D) mouse model. Diabetes. 2012;61:1250-62 pubmed 出版商 |
| Collins M, Bednar F, Zhang Y, Brisset J, Galban S, Galban C, et al. Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice. J Clin Invest. 2012;122:639-53 pubmed 出版商 |
| CARRIERE C, Young A, Gunn J, Longnecker D, Korc M. Acute pancreatitis accelerates initiation and progression to pancreatic cancer in mice expressing oncogenic Kras in the nestin cell lineage. PLoS ONE. 2011;6:e27725 pubmed 出版商 |
| Snider N, Weerasinghe S, Singla A, Leonard J, Hanada S, Andrews P, et al. Energy determinants GAPDH and NDPK act as genetic modifiers for hepatocyte inclusion formation. J Cell Biol. 2011;195:217-29 pubmed 出版商 |
| Whipple C, Young A, Korc M. A KrasG12D-driven genetic mouse model of pancreatic cancer requires glypican-1 for efficient proliferation and angiogenesis. Oncogene. 2012;31:2535-44 pubmed 出版商 |
| Ying H, Elpek K, Vinjamoori A, Zimmerman S, Chu G, Yan H, et al. PTEN is a major tumor suppressor in pancreatic ductal adenocarcinoma and regulates an NF-?B-cytokine network. Cancer Discov. 2011;1:158-69 pubmed 出版商 |
| Philips G, Chan I, Swiderska M, Schroder V, Guy C, Karaca G, et al. Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer. PLoS ONE. 2011;6:e23943 pubmed 出版商 |
| Kosoff R, Gardiner K, Merlo L, Pavlov K, Rustgi A, Maley C. Development and characterization of an organotypic model of Barrett's esophagus. J Cell Physiol. 2012;227:2654-9 pubmed 出版商 |
| Van Hul N, Lanthier N, Español Suñer R, Abarca Quinones J, Van Rooijen N, Leclercq I. Kupffer cells influence parenchymal invasion and phenotypic orientation, but not the proliferation, of liver progenitor cells in a murine model of liver injury. Am J Pathol. 2011;179:1839-50 pubmed 出版商 |
| Sans M, Sabbatini M, Ernst S, D Alecy L, Nishijima I, Williams J. Secretin is not necessary for exocrine pancreatic development and growth in mice. Am J Physiol Gastrointest Liver Physiol. 2011;301:G791-8 pubmed 出版商 |
| Criscimanna A, Speicher J, Houshmand G, Shiota C, Prasadan K, Ji B, et al. Duct cells contribute to regeneration of endocrine and acinar cells following pancreatic damage in adult mice. Gastroenterology. 2011;141:1451-62, 1462.e1-6 pubmed 出版商 |
| Hertel P, Crawford S, Finegold M, Estes M. Osteopontin upregulation in rotavirus-induced murine biliary atresia requires replicating virus but is not necessary for development of biliary atresia. Virology. 2011;417:281-92 pubmed 出版商 |
| Fiorotto R, Scirpo R, Trauner M, Fabris L, Hoque R, Spirli C, et al. Loss of CFTR affects biliary epithelium innate immunity and causes TLR4-NF-?B-mediated inflammatory response in mice. Gastroenterology. 2011;141:1498-508, 1508.e1-5 pubmed 出版商 |
| Heid I, Lubeseder Martellato C, Sipos B, Mazur P, Lesina M, Schmid R, et al. Early requirement of Rac1 in a mouse model of pancreatic cancer. Gastroenterology. 2011;141:719-30, 730.e1-7 pubmed 出版商 |
| Guerra C, Collado M, Navas C, Schuhmacher A, Hernández Porras I, Canamero M, et al. Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence. Cancer Cell. 2011;19:728-39 pubmed 出版商 |
| Chu A, Diaz R, Hui J, Yanger K, Zong Y, Alpini G, et al. Lineage tracing demonstrates no evidence of cholangiocyte epithelial-to-mesenchymal transition in murine models of hepatic fibrosis. Hepatology. 2011;53:1685-95 pubmed 出版商 |
| Sparks E, Perrien D, Huppert K, Peterson T, Huppert S. Defects in hepatic Notch signaling result in disruption of the communicating intrahepatic bile duct network in mice. Dis Model Mech. 2011;4:359-67 pubmed 出版商 |
| Habtezion A, Toivola D, Asghar M, Kronmal G, Brooks J, Butcher E, et al. Absence of keratin 8 confers a paradoxical microflora-dependent resistance to apoptosis in the colon. Proc Natl Acad Sci U S A. 2011;108:1445-50 pubmed 出版商 |
| Lee K, Bar Sagi D. Oncogenic KRas suppresses inflammation-associated senescence of pancreatic ductal cells. Cancer Cell. 2010;18:448-58 pubmed 出版商 |
| Omenetti A, Yang L, Gainetdinov R, Guy C, Choi S, Chen W, et al. Paracrine modulation of cholangiocyte serotonin synthesis orchestrates biliary remodeling in adults. Am J Physiol Gastrointest Liver Physiol. 2011;300:G303-15 pubmed 出版商 |
| Hofmann J, Zovein A, Koh H, Radtke F, Weinmaster G, Iruela Arispe M. Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome. Development. 2010;137:4061-72 pubmed 出版商 |
| Snider N, Weerasinghe S, INIGUEZ LLUHI J, Herrmann H, Omary M. Keratin hypersumoylation alters filament dynamics and is a marker for human liver disease and keratin mutation. J Biol Chem. 2011;286:2273-84 pubmed 出版商 |
| Zhou Q, Snider N, Liao J, Li D, Hong A, Ku N, et al. Characterization of in vivo keratin 19 phosphorylation on tyrosine-391. PLoS ONE. 2010;5:e13538 pubmed 出版商 |
| Lin T, Meng L, Li Y, Tsai R. Tumor-initiating function of nucleostemin-enriched mammary tumor cells. Cancer Res. 2010;70:9444-52 pubmed 出版商 |
| Marzioni M, Saccomanno S, Candelaresi C, Rychlicki C, Agostinelli L, Shanmukhappa K, et al. Pancreatic Duodenal Homeobox-1 de novo expression drives cholangiocyte neuroendocrine-like transdifferentiation. J Hepatol. 2010;53:663-70 pubmed 出版商 |
| Scholten D, Osterreicher C, Scholten A, Iwaisako K, Gu G, Brenner D, et al. Genetic labeling does not detect epithelial-to-mesenchymal transition of cholangiocytes in liver fibrosis in mice. Gastroenterology. 2010;139:987-98 pubmed 出版商 |
| Osada M, Jardine L, Misir R, Andl T, Millar S, Pezzano M. DKK1 mediated inhibition of Wnt signaling in postnatal mice leads to loss of TEC progenitors and thymic degeneration. PLoS ONE. 2010;5:e9062 pubmed 出版商 |
| Copple B. Hypoxia stimulates hepatocyte epithelial to mesenchymal transition by hypoxia-inducible factor and transforming growth factor-beta-dependent mechanisms. Liver Int. 2010;30:669-82 pubmed 出版商 |
| Hanada S, Snider N, Brunt E, Hollenberg P, Omary M. Gender dimorphic formation of mouse Mallory-Denk bodies and the role of xenobiotic metabolism and oxidative stress. Gastroenterology. 2010;138:1607-17 pubmed 出版商 |
| Labarge M, Nelson C, Villadsen R, Fridriksdottir A, Ruth J, Stampfer M, et al. Human mammary progenitor cell fate decisions are products of interactions with combinatorial microenvironments. Integr Biol (Camb). 2009;1:70-9 pubmed 出版商 |
| Sun P, Yuan Y, Li A, Li B, Dai X. Cytokeratin expression during mouse embryonic and early postnatal mammary gland development. Histochem Cell Biol. 2010;133:213-21 pubmed 出版商 |
| Soroka C, Mennone A, Hagey L, Ballatori N, Boyer J. Mouse organic solute transporter alpha deficiency enhances renal excretion of bile acids and attenuates cholestasis. Hepatology. 2010;51:181-90 pubmed 出版商 |
| Sackett S, Gao Y, Shin S, Esterson Y, Tsingalia A, Hurtt R, et al. Foxl1 promotes liver repair following cholestatic injury in mice. Lab Invest. 2009;89:1387-96 pubmed 出版商 |
| Loebermann M, Sombetzki M, Langner C, Fuchsbichler A, Gumhold J, Silbert D, et al. Imbalance of pro- and antifibrogenic genes and bile duct injury in murine Schistosoma mansoni infection-induced liver fibrosis. Trop Med Int Health. 2009;14:1418-25 pubmed 出版商 |
| Zhong B, Strnad P, Selmi C, Invernizzi P, Tao G, Caleffi A, et al. Keratin variants are overrepresented in primary biliary cirrhosis and associate with disease severity. Hepatology. 2009;50:546-54 pubmed 出版商 |
| VanSaun M, Lee I, Washington M, Matrisian L, Gorden D. High fat diet induced hepatic steatosis establishes a permissive microenvironment for colorectal metastases and promotes primary dysplasia in a murine model. Am J Pathol. 2009;175:355-64 pubmed 出版商 |
| Halilbasic E, Fiorotto R, Fickert P, Marschall H, Moustafa T, Spirli C, et al. Side chain structure determines unique physiologic and therapeutic properties of norursodeoxycholic acid in Mdr2-/- mice. Hepatology. 2009;49:1972-81 pubmed 出版商 |
| Li Z, White P, Tuteja G, Rubins N, Sackett S, Kaestner K. Foxa1 and Foxa2 regulate bile duct development in mice. J Clin Invest. 2009;119:1537-45 pubmed 出版商 |
| von Burstin J, Eser S, Paul M, Seidler B, Brandl M, Messer M, et al. E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex. Gastroenterology. 2009;137:361-71, 371.e1-5 pubmed 出版商 |
| Van Hul N, Abarca Quinones J, Sempoux C, Horsmans Y, Leclercq I. Relation between liver progenitor cell expansion and extracellular matrix deposition in a CDE-induced murine model of chronic liver injury. Hepatology. 2009;49:1625-35 pubmed 出版商 |
| CARRIERE C, Young A, Gunn J, Longnecker D, Korc M. Acute pancreatitis markedly accelerates pancreatic cancer progression in mice expressing oncogenic Kras. Biochem Biophys Res Commun. 2009;382:561-5 pubmed 出版商 |
| Tian H, Callahan C, DuPree K, Darbonne W, Ahn C, Scales S, et al. Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis. Proc Natl Acad Sci U S A. 2009;106:4254-9 pubmed 出版商 |
| Roda O, Ortiz Zapater E, Martínez Bosch N, Gutiérrez Gallego R, Vila Perello M, Ampurdanés C, et al. Galectin-1 is a novel functional receptor for tissue plasminogen activator in pancreatic cancer. Gastroenterology. 2009;136:1379-90, e1-5 pubmed 出版商 |
| Mohammad M, Raftos D, Joss J. Cytoskeletal proteins in thymic epithelial cells of the Australian lungfish Neoceratodus forsteri. J Anat. 2009;214:140-52 pubmed 出版商 |
| Stairs D, Nakagawa H, Klein Szanto A, Mitchell S, Silberg D, Tobias J, et al. Cdx1 and c-Myc foster the initiation of transdifferentiation of the normal esophageal squamous epithelium toward Barrett's esophagus. PLoS ONE. 2008;3:e3534 pubmed 出版商 |
| Feng N, Kim B, Fenaux M, Nguyen H, Vo P, Omary M, et al. Role of interferon in homologous and heterologous rotavirus infection in the intestines and extraintestinal organs of suckling mice. J Virol. 2008;82:7578-90 pubmed 出版商 |
| Pangas S, Li X, Umans L, Zwijsen A, Huylebroeck D, Gutierrez C, et al. Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice. Mol Cell Biol. 2008;28:248-57 pubmed |
| Zhong B, Strnad P, Toivola D, Tao G, Ji X, Greenberg H, et al. Reg-II is an exocrine pancreas injury-response product that is up-regulated by keratin absence or mutation. Mol Biol Cell. 2007;18:4969-78 pubmed |
| Pangas S, Jorgez C, Tran M, Agno J, Li X, Brown C, et al. Intraovarian activins are required for female fertility. Mol Endocrinol. 2007;21:2458-71 pubmed |
| Wu R, Hendrix Lucas N, Kuick R, Zhai Y, Schwartz D, Akyol A, et al. Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways. Cancer Cell. 2007;11:321-33 pubmed |
| CARRIERE C, Seeley E, Goetze T, Longnecker D, Korc M. The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia. Proc Natl Acad Sci U S A. 2007;104:4437-42 pubmed |
| Michon F, Charveron M, Dhouailly D. Dermal condensation formation in the chick embryo: requirement for integrin engagement and subsequent stabilization by a possible notch/integrin interaction. Dev Dyn. 2007;236:755-68 pubmed |
| Pasca di Magliano M, Sekine S, Ermilov A, Ferris J, Dlugosz A, Hebrok M. Hedgehog/Ras interactions regulate early stages of pancreatic cancer. Genes Dev. 2006;20:3161-73 pubmed |
| Fickert P, Wagner M, Marschall H, Fuchsbichler A, Zollner G, Tsybrovskyy O, et al. 24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice. Gastroenterology. 2006;130:465-81 pubmed |
| Kuang C, Xiao Y, Liu X, Stringfield T, Zhang S, Wang Z, et al. In vivo disruption of TGF-beta signaling by Smad7 leads to premalignant ductal lesions in the pancreas. Proc Natl Acad Sci U S A. 2006;103:1858-63 pubmed |
| Fickert P, Fuchsbichler A, Marschall H, Wagner M, Zollner G, Krause R, et al. Lithocholic acid feeding induces segmental bile duct obstruction and destructive cholangitis in mice. Am J Pathol. 2006;168:410-22 pubmed |
| Zhong B, Zhou Q, Toivola D, Tao G, Resurreccion E, Omary M. Organ-specific stress induces mouse pancreatic keratin overexpression in association with NF-kappaB activation. J Cell Sci. 2004;117:1709-19 pubmed |
| Toivola D, Krishnan S, Binder H, Singh S, Omary M. Keratins modulate colonocyte electrolyte transport via protein mistargeting. J Cell Biol. 2004;164:911-21 pubmed |
| Brulet P, Babinet C, Kemler R, Jacob F. Monoclonal antibodies against trophectoderm-specific markers during mouse blastocyst formation. Proc Natl Acad Sci U S A. 1980;77:4113-7 pubmed |
| Kemler R, Brulet P, Schnebelen M, Gaillard J, Jacob F. Reactivity of monoclonal antibodies against intermediate filament proteins during embryonic development. J Embryol Exp Morphol. 1981;64:45-60 pubmed |
