产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
synaptotagmin-1, cytoplasmic domain
目录 :
mAb 48 (asv 48)
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
mAb 48 (asv 48)
反应物种 :
人类, 小鼠, 大鼠, 鸡
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀
更多信息或购买 :
Developmental Studies Hybridoma Bank 产品网页
文章摘录数: 10
参考文献
Fogerson S, van Brummen A, Busch D, Allen S, Roychaudhuri R, Banks S, et al. Reducing synuclein accumulation improves neuronal survival after spinal cord injury. Exp Neurol. 2016;278:105-15 pubmed 出版商
Taguchi K, Watanabe Y, Tsujimura A, Tanaka M. Brain region-dependent differential expression of alpha-synuclein. J Comp Neurol. 2016;524:1236-58 pubmed 出版商
Moritz C, Eckstein E, Tenzer S, Friauf E. Neuroproteomics in the auditory brainstem: candidate proteins for ultrafast and precise information processing. Mol Cell Neurosci. 2015;64:9-23 pubmed 出版商
Dagley L, White C, Liao Y, Shi W, Smyth G, Orian J, et al. Quantitative proteomic profiling reveals novel region-specific markers in the adult mouse brain. Proteomics. 2014;14:241-61 pubmed 出版商
Lau B, Fogerson S, Walsh R, Morgan J. Cyclic AMP promotes axon regeneration, lesion repair and neuronal survival in lampreys after spinal cord injury. Exp Neurol. 2013;250:31-42 pubmed 出版商
Casas C, Herrando Grabulosa M, Manzano R, Mancuso R, Osta R, Navarro X. Early presymptomatic cholinergic dysfunction in a murine model of amyotrophic lateral sclerosis. Brain Behav. 2013;3:145-58 pubmed 出版商
Cooper A, Gillespie D. Synaptotagmins I and II in the developing rat auditory brainstem: Synaptotagmin I is transiently expressed in glutamate-releasing immature inhibitory terminals. J Comp Neurol. 2011;519:2417-33 pubmed 出版商
Fox M, Sanes J. Synaptotagmin I and II are present in distinct subsets of central synapses. J Comp Neurol. 2007;503:280-96 pubmed
Matthew W, Tsavaler L, Reichardt L. Identification of a synaptic vesicle-specific membrane protein with a wide distribution in neuronal and neurosecretory tissue. J Cell Biol. 1981;91:257-69 pubmed
Greif K, Reichardt L. Appearance and distribution of neuronal cell surface and synaptic vesicle antigens in the developing rat superior cervical ganglion. J Neurosci. 1982;2:843-52 pubmed
产品信息
内部号码 :
1493
名称 :
mAb 48 (asv 48)
Depositor Name :
Reichardt, L.
Depositor Institution :
Department of Physiology, University of California
Date Deposited :
4/20/99
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
抗原 :
synaptotagmin-1, cytoplasmic domain
抗原物种 :
大鼠
宿主物种 :
小鼠
抗体亚型 :
MIgG2b, kappa light chain
Isotype for catalog (legacy) :
IgG2b, kappa light chain
Positive Tested Species Reactivity :
鸡, 鱼类, 人类, 八目鳗, 小鼠, 大鼠, 蛙, 斑马鱼
Species Tested (legacy) :
fish, Xenopus, chick, mouse, rat, Zebrafish and human
Initial Publication Pubmed ID :
7298720
Depositor Notes (Special Instructions) :
Not available to for-profit organizations. For further information please contact the Office of Innovation, Technology, and Alliances at the University of California. Refer to case number 95-082. Email : ita@ucsf.edu Telephone: 415 502-1603. Researchers at non-profit institutions must sign an additional compliance form prior to purchasing this antibody. The compliance form is available by emailing dshb@uiowa.edu or by calling 319 335-3826.
Collections :
Cell markers,Human,Neurodevelopment
搜索关键词 :
Reichardt, synaptotagmin 1, cytoplasmic domain, Syt1, P65, monoclonal, AB_2199314, IgG2b, Chicken,Fish,Human,Lamprey,Mouse,Rat,Xenopus,Zebrafish, ELISA,Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot
抗原分子量 :
Predicted: 47 kDa; Apparent: 65 kDa
基因 :
Syt1
Alternate Gene Name(s) :
P65
UniProt数据库编号 :
P21707
抗体登记处号码 :
AB_2199314
Synonyms (Alternate Clone Names) :
SV 48
免疫原 :
Synaptic junctional complex proteins prepared from rat brain synaptic membranes
免疫原序列 :
全长蛋白
克隆性 :
单克隆
Myeloma Strain :
NS-1
表位定位 :
Yes
Epitope Location or Sequence :
Cytoplasmic (aa 80-421)
Recommended Applications :
酶联免疫吸附测定, 免疫荧光, 免疫组化, 免疫沉淀, 免疫印迹
Immunoblotting (legacy) :
Yes, detergent sensitive
免疫组化PubMed IDs :
7298720 6212651 21456023
免疫荧光PubMed IDs :
17492637 21456023 24041988 26854933 25131618 23531559 26358191
免疫印迹PubMed IDs :
7298720 17492637 24041988 24259518 24041988 31399955 31399955
免疫沉淀PubMed IDs :
17492637
其他信息 :
This antibody was validated for tissue fixed with 4% paraformaldehyde and cryosections following OCT embedding. Detergent sensitive / Triton X-100. This antibody recognizes synaptotagmin 1 and does not cross react with synaptotagmin 2. See Fox and Sanes (2007, PUDMED 17492637). mAb 48 (asv 48) has a higher affinity than mAb 30 (asv30). The two antibodies recognize the same antigen, Syt1.
DSHB增长培养基 :
Iscove's
References (legacy) :
J. Cell Biol. 81, 257-269; J. Neurosci. 2, 843-852.; J. Comp. Neurol. 503, 280-296.; J. Comp. Neurol. 519, 2417-2433.
更多信息或购买 :
Developmental Studies Hybridoma Bank 产品网页
公司信息
Developmental Studies Hybridoma Bank
University of Iowa
dshb@uiowa.edu
http://dshb.biology.uiowa.edu
公司总部: 美国
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构，为生命科学研究领域及诊断领域，提供高质量的抗体等产品。