产品简要
公司名称 :
Dianova
产品类型 :
抗体
产品名称 :
Anti-CD31 (Ms) from Rat (Clone: SZ31) for mouse FFPE tissue
目录 :
DIA-310
规格 :
500微升
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
SZ31
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片
更多信息或购买 :
文章摘录数: 101
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 小鼠; 1:10; 图 7f
Kettwig M, Ternka K, Wendland K, Krüger D, Zampar S, Schob C, et al. Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy. Nat Commun. 2021;12:6530 pubmed 出版商
  • 免疫组化; 小鼠; 图 s2
Gurley J, Gmyrek G, Hargis E, Bishop G, Carr D, Elliott M. The Chx10-Traf3 Knockout Mouse as a Viable Model to Study Neuronal Immune Regulation. Cells. 2021;10: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 7e
Bruand M, Barras D, Mina M, Ghisoni E, Morotti M, Lanitis E, et al. Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING. Cell Rep. 2021;36:109412 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 3f
Yan C, Saleh N, Yang J, Nebhan C, Vilgelm A, Reddy E, et al. Novel induction of CD40 expression by tumor cells with RAS/RAF/PI3K pathway inhibition augments response to checkpoint blockade. Mol Cancer. 2021;20:85 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 2e
Komeno M, Pang X, Shimizu A, Molla M, Yasuda Yamahara M, Kume S, et al. Cardio- and reno-protective effects of dipeptidyl peptidase III in diabetic mice. J Biol Chem. 2021;296:100761 pubmed 出版商
  • 免疫组化; 小鼠; 1:50; 图 4a
Moore K, Fulmer D, Guo L, Koren N, Glover J, Moore R, et al. PDGFRα: Expression and Function during Mitral Valve Morphogenesis. J Cardiovasc Dev Dis. 2021;8: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 s4
Gurley J, Gmyrek G, McClellan M, Hargis E, Hauck S, Dozmorov M, et al. Neuroretinal-Derived Caveolin-1 Promotes Endotoxin-Induced Inflammation in the Murine Retina. Invest Ophthalmol Vis Sci. 2020;61:19 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 2a
Alonso Herranz L, Sahún Español Á, Paredes A, Gonzalo P, Gkontra P, Núñez V, et al. Macrophages promote endothelial-to-mesenchymal transition via MT1-MMP/TGFβ1 after myocardial infarction. elife. 2020;9: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 5f
Schmitt B, Boewe A, Becker V, Nalbach L, Gu Y, Götz C, et al. Protein Kinase CK2 Regulates Nerve/Glial Antigen (NG)2-Mediated Angiogenic Activity of Human Pericytes. Cells. 2020;9: pubmed 出版商
  • 免疫组化; 小鼠; 1:50; 图 8e
Devraj G, Guérit S, Seele J, Spitzer D, Macas J, Khel M, et al. HIF-1α is involved in blood-brain barrier dysfunction and paracellular migration of bacteria in pneumococcal meningitis. Acta Neuropathol. 2020;140:183-208 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 3c
Resovi A, Borsotti P, Ceruti T, Passoni A, Zucchetti M, Berndt A, et al. CCN-Based Therapeutic Peptides Modify Pancreatic Ductal Adenocarcinoma Microenvironment and Decrease Tumor Growth in Combination with Chemotherapy. Cells. 2020;9: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:600; 图 6a
Facchin C, Pérez Liva M, Garofalakis A, Viel T, Certain A, Balvay D, et al. Concurrent imaging of vascularization and metabolism in a mouse model of paraganglioma under anti-angiogenic treatment. Theranostics. 2020;10:3518-3532 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 1a, 7s4b
Engelbrecht E, Lévesque M, He L, Vanlandewijck M, Nitzsche A, Niazi H, et al. Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta. elife. 2020;9: pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:250; 图 6d
Collins L, Brunjes P. The mouse olfactory peduncle 4: Development of synapses, perineuronal nets, and capillaries. J Comp Neurol. 2019;: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 6h
Farbehi N, Patrick R, Dorison A, Xaymardan M, Janbandhu V, Wystub Lis K, et al. Single-cell expression profiling reveals dynamic flux of cardiac stromal, vascular and immune cells in health and injury. elife. 2019;8: pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 3s1b
Basnet H, Tian L, Ganesh K, Huang Y, Macalinao D, Brogi E, et al. Flura-seq identifies organ-specific metabolic adaptations during early metastatic colonization. elife. 2019;8: pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:250; 图 1f
  • 免疫组化; 小鼠; 1:250; 图 5a
Hess D, Kelly Goss M, Cherepanova O, Nguyen A, Baylis R, Tkachenko S, et al. Perivascular cell-specific knockout of the stem cell pluripotency gene Oct4 inhibits angiogenesis. Nat Commun. 2019;10:967 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 4
Low S, Hirakawa J, Hoshino H, Uchimura K, Kawashima H, Kobayashi M. Role of MAdCAM-1-Expressing High Endothelial Venule-Like Vessels in Colitis Induced in Mice Lacking Sulfotransferases Catalyzing L-Selectin Ligand Biosynthesis. J Histochem Cytochem. 2018;66:415-425 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:20; 图 s5a
Tang A, Choi J, Kotzin J, Yang Y, Hong C, Hobson N, et al. Endothelial TLR4 and the microbiome drive cerebral cavernous malformations. Nature. 2017;545:305-310 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:100; 图 s3
  • 免疫印迹; 小鼠; 1:2000; 图 3b
Yanagida K, Liu C, Faraco G, Galvani S, Smith H, Burg N, et al. Size-selective opening of the blood-brain barrier by targeting endothelial sphingosine 1-phosphate receptor 1. Proc Natl Acad Sci U S A. 2017;114:4531-4536 pubmed 出版商
  • 免疫组化; 小鼠; 1 ug/ml; 图 S5
Fonseca M, Chu S, Hernandez M, Fang M, Modarresi L, Selvan P, et al. Cell-specific deletion of C1qa identifies microglia as the dominant source of C1q in mouse brain. J Neuroinflammation. 2017;14:48 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 2 ug/ml
  • 免疫组化; 人类; 图 55
Furukawa S, Nagaike M, Ozaki K. Databases for technical aspects of immunohistochemistry. J Toxicol Pathol. 2017;30:79-107 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 5l
Patschan D, Schwarze K, Tampe B, Zeisberg M, Patschan S, Muller G. Endothelial Colony Forming Cells (ECFCs) in murine AKI - implications for future cell-based therapies. BMC Nephrol. 2017;18:53 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 s2a
de Jong R, Paulin N, Lemnitzer P, Viola J, Winter C, Ferraro B, et al. Protective Aptitude of Annexin A1 in Arterial Neointima Formation in Atherosclerosis-Prone Mice-Brief Report. Arterioscler Thromb Vasc Biol. 2017;37:312-315 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 0.5 ug/ml; 图 4a
Nayak T, Andreou C, Oseledchyk A, Marcus W, Wong H, Massague J, et al. Tissue factor-specific ultra-bright SERRS nanostars for Raman detection of pulmonary micrometastases. Nanoscale. 2017;9:1110-1119 pubmed 出版商
  • 免疫印迹; 小鼠
Kühnel E, Kleff V, Stojanovska V, Kaiser S, Waldschütz R, Herse F, et al. Placental-Specific Overexpression of sFlt-1 Alters Trophoblast Differentiation and Nutrient Transporter Expression in an IUGR Mouse Model. J Cell Biochem. 2017;118:1316-1329 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 s10d
Goebbels S, Wieser G, Pieper A, Spitzer S, Weege B, Yan K, et al. A neuronal PI(3,4,5)P3-dependent program of oligodendrocyte precursor recruitment and myelination. Nat Neurosci. 2017;20:10-15 pubmed 出版商
  • 免疫组化; 人类; 1:75; 图 s14
Frentzas S, Simoneau E, Bridgeman V, Vermeulen P, Foo S, Kostaras E, et al. Vessel co-option mediates resistance to anti-angiogenic therapy in liver metastases. Nat Med. 2016;22:1294-1302 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 图 2
Klose R, Krzywinska E, Castells M, Gotthardt D, Putz E, Kantari Mimoun C, et al. Targeting VEGF-A in myeloid cells enhances natural killer cell responses to chemotherapy and ameliorates cachexia. Nat Commun. 2016;7:12528 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6
Inoue T, Ikeda M, Ide T, Fujino T, Matsuo Y, Arai S, et al. Twinkle overexpression prevents cardiac rupture after myocardial infarction by alleviating impaired mitochondrial biogenesis. Am J Physiol Heart Circ Physiol. 2016;311:H509-19 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:20; 图 s3
Chen I, Caprioli A, Ohnuki H, Kwak H, Porcher C, Tosato G. EphrinB2 regulates the emergence of a hemogenic endothelium from the aorta. Sci Rep. 2016;6:27195 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 5d
Osterloh A, Papp S, Moderzynski K, Kuehl S, Richardt U, Fleischer B. Persisting Rickettsia typhi Causes Fatal Central Nervous System Inflammation. Infect Immun. 2016;84:1615-1632 pubmed 出版商
  • 免疫组化; 小鼠; 1:50; 图 3
Kraft Sheleg O, Zaffryar Eilot S, Genin O, Yaseen W, Soueid Baumgarten S, Kessler O, et al. Localized LoxL3-Dependent Fibronectin Oxidation Regulates Myofiber Stretch and Integrin-Mediated Adhesion. Dev Cell. 2016;36:550-61 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 4
Rusckowski M, Wang Y, Blankenberg F, Levashova Z, Backer M, Backer J. Targeted scVEGF/(177)Lu radiopharmaceutical inhibits growth of metastases and can be effectively combined with chemotherapy. EJNMMI Res. 2016;6:4 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠
  • 免疫组化-石蜡切片; 小鼠; 图 5
Dimitrova N, Gocheva V, Bhutkar A, Resnick R, Jong R, Miller K, et al. Stromal Expression of miR-143/145 Promotes Neoangiogenesis in Lung Cancer Development. Cancer Discov. 2016;6:188-201 pubmed 出版商
  • 免疫细胞化学; 人类; 1:20; 图 2b
Mikami J, Kurokawa Y, Takahashi T, Miyazaki Y, Yamasaki M, Miyata H, et al. Antitumor effect of antiplatelet agents in gastric cancer cells: an in vivo and in vitro study. Gastric Cancer. 2016;19:817-26 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:150; 图 7
Janssen L, Dupont L, Bekhouche M, Noel A, Leduc C, Voz M, et al. ADAMTS3 activity is mandatory for embryonic lymphangiogenesis and regulates placental angiogenesis. Angiogenesis. 2016;19:53-65 pubmed 出版商
  • 免疫组化; 小鼠; 1:25; 图 6a
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  • 免疫组化-石蜡切片; 小鼠; 图 3
Dmitrieva N, Burg M. Elevated sodium and dehydration stimulate inflammatory signaling in endothelial cells and promote atherosclerosis. PLoS ONE. 2015;10:e0128870 pubmed 出版商
  • 免疫组化; 小鼠; 图 3
Yarilin D, Xu K, Turkekul M, Fan N, Romin Y, Fijisawa S, et al. Machine-based method for multiplex in situ molecular characterization of tissues by immunofluorescence detection. Sci Rep. 2015;5:9534 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 1c
Salvucci O, Ohnuki H, Maric D, Hou X, Li X, Yoon S, et al. EphrinB2 controls vessel pruning through STAT1-JNK3 signalling. Nat Commun. 2015;6:6576 pubmed 出版商
  • 免疫组化; 人类; 1:50; 图 s3c
  • 免疫组化; 小鼠; 1:50; 图 2a
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Doloff J, Chen C, Waxman D. Anti-tumor innate immunity activated by intermittent metronomic cyclophosphamide treatment of 9L brain tumor xenografts is preserved by anti-angiogenic drugs that spare VEGF receptor 2. Mol Cancer. 2014;13:158 pubmed 出版商
Kono M, Tucker A, Tran J, Bergner J, Turner E, Proia R. Sphingosine-1-phosphate receptor 1 reporter mice reveal receptor activation sites in vivo. J Clin Invest. 2014;124:2076-86 pubmed 出版商
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图像
图像 1 :
Dianova DIA-310 图像 1
The monoclonal antibody clone SZ31 reacts specifically with endothelial cells in vessels and capillaries of (among others) mouse small intestine.
图像 2 :
Dianova DIA-310 图像 2
The monoclonal antibody clone SZ31 reacts specifically with endothelial cells in vessels and capillaries of (among others) mouse liver.
图像 3 :
Dianova DIA-310 图像 3
Immunoblot of extracts from murine lung, J558L cells and m-Lend cells using CD31 rat monoclonal antibody clone SZ31.
产品信息
目录代码 :
DIA-310
产品名称 :
Anti-CD31 (Ms) from Rat (Clone: SZ31) for mouse FFPE tissue
产品类型 :
抗体
宿主物种 :
大鼠
克隆性 :
单克隆
共轭 :
未共轭
克隆名称 :
SZ31
抗体亚型 :
IgG2a
规格 :
500微升
产品描述 :
Antibody clone SZ31 is the first antibody which reacts specifically with murine CD31 in formalin-fixed paraffin-embedded tissue sections.
交叉活性 :
does not cross-react with rat or human
背景 :
CD31, also known as PECAM-1 (Platelet Endothelial Cell Adhesion Molecule-1) is expressed constitutively on the surface of embryonic and adult endothelial cells. It is also expressed on cell surfaces of monocytes, neutrophils, platelets and certain T-cell subsets. It has been detected on bone marrow-derived hematopoetic stem cells and embryonic stem cells. Cluster of Differentiation 31 (CD31) is a 130kDa integral membrane glycoprotein and as a member of the immunoglobulin superfamily involved in the mediation of cell-to-cell adhesion. CD31-mediated endothelial cell-cell interactions play a major role in angiogenesis. Studies have shown CD31 to be a superior marker in human angiogenesis, which reportedly predicts tumor recurrence. Pathophysiological studies of CD31 in murine model systems had limitations because standard formalin-fixed sections were excluded. The clone SZ31 (Anti-CD31) eliminates these restrictions by allowing high quality immunohistochemical analysis of standard formalin-fixed paraffin sections in mice.
别名 :
PECAM-1(血小板内皮细胞 粘连分子1)
免疫原 :
Murine amino acid fragment
特异性 :
Murine CD31 (PECAM-1) (adult and embryonic endothelial cells)
纯度 :
纯化
防腐剂 :
0.05% NaN3
浓度 :
0.2毫克/毫升
应用摘要 :
免疫组化-F;免疫组化-P;免疫印迹
更多信息或购买 :
公司信息
Dianova
Warburgstr. 45
D-20354 Hamburg
info@dianova.de
http://www.dianova.de
49 40 45 06 73 30
公司总部: 德国
Since its foundation in 1982, dianova GmbH provides professionals in Life Sciences with antibodies, immunoassays, and products for molecular biology. More than 30 years of grown expertise give rise to a fundamental knowledge about biochemical applications and a profound understanding of customer needs in research and routine diagnostic laboratories of universities, hospitals and the pharmaceutical industry.
Since its foundation in 1982, dianova GmbH provides professionals in Life Sciences with antibodies, immunoassays, and products for molecular biology. More than 30 years of grown expertise give rise to a fundamental knowledge about biochemical applications and a profound understanding of customer needs in research and routine diagnostic laboratories of universities, hospitals and the pharmaceutical industry.
In addition to distributing Life Science and Diagnostic Products in the German speaking region dianova manufactures and markets a series of antibodies with unique properties on a worldwide basis under the brand of optistain. To this end dianova has successfully established a distribution network in more than 25 countries.
At dianova quality is of paramount importance and subject to strict control. Internal controls and audits are carried out in addition to on-site inspections by independent, external inspection companies. In 2003 the TÜV Rheinland/Berlin/Brandenburg successfully completed the first comprehensive certification process. Since then dianova has been certified pursuant to the international DIN EN ISO 9001:2008 standard.