产品简要
公司名称 :
Dianova
产品类型 :
抗体
产品名称 :
Anti-p53 (Hu) from Mouse (Clone: CC53)
目录 :
DIA-530-P05
规格 :
500微升
价格 :
167 EUR plus VAT
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
CC53
反应物种 :
人类
应用 :
免疫组化-石蜡切片
更多信息或购买 :
图像
图像 1 :
Dianova DIA-530-P05 图像 1
(A) Squamous cell carcinoma of the neck. Nearly all tumor cells are strongly p53 positive in their nuclei. (B) Colon carcinoma. Nearly all tumor cells are strongly p53 positive in their nuclei.
产品信息
目录代码 :
DIA-530-P05
产品名称 :
Anti-p53 (Hu) from Mouse (Clone: CC53)
产品类型 :
抗体
宿主物种 :
小鼠
克隆性 :
单克隆
共轭 :
nonconjugated
克隆名称 :
CC53
抗体亚型 :
IgG1
规格 :
500微升
标价 :
167 EUR plus VAT
背景 :
The p53 tumor suppressor gene has been found to contain mutations in over 50% of human cancers. Many mutations of the p53 gene have been associated with malignant transformation in a wide variety of human tumors. p53 immunostaining is of use in demonstrating accumulation of p53 protein, which occurs in a high frequency in a wide variety of transformed cells. Anti-p53 Tumor Suppressor Protein antibody recognizes a 53 kDa phosphoprotein, identified as p53 suppressor gene product. It reacts with the mutant as well as wild form of p53. Positive nuclear staining with this antibody has been shown to be a negative prognostic factor in Breast carcinoma, Lung carcinoma, Colorectal, and Urothelial carcinoma. p53 positivity has also been used to differentiate Uterine serous carcinoma from endometrioid carcinoma as well as to detect Intratubular germ cell neoplasia. Moreover antibody clone CC53 helps to detect single invading astrocytoma-cells
免疫原 :
Recombinant, human wild type p53
定位 :
Nuclear
特异性 :
Human p53, wild type and mutated
纯度 :
纯化
防腐剂 :
0.05% NaN3
应用摘要 :
免疫组化-P
更多信息或购买 :
公司信息
Dianova
Warburgstr. 45
D-20354 Hamburg
info@dianova.de
www.dianova.de
49 40 45 06 73 30
公司总部: 德国
Since its foundation in 1982, dianova GmbH provides professionals in Life Sciences with antibodies, immunoassays, and products for molecular biology. More than 30 years of grown expertise give rise to a fundamental knowledge about biochemical applications and a profound understanding of customer needs in research and routine diagnostic laboratories of universities, hospitals and the pharmaceutical industry.
Since its foundation in 1982, dianova GmbH provides professionals in Life Sciences with antibodies, immunoassays, and products for molecular biology. More than 30 years of grown expertise give rise to a fundamental knowledge about biochemical applications and a profound understanding of customer needs in research and routine diagnostic laboratories of universities, hospitals and the pharmaceutical industry.
In addition to distributing Life Science and Diagnostic Products in the German speaking region dianova manufactures and markets a series of antibodies with unique properties on a worldwide basis under the brand of optistain. To this end dianova has successfully established a distribution network in more than 25 countries.
At dianova quality is of paramount importance and subject to strict control. Internal controls and audits are carried out in addition to on-site inspections by independent, external inspection companies. In 2003 the TÜV Rheinland/Berlin/Brandenburg successfully completed the first comprehensive certification process. Since then dianova has been certified pursuant to the international DIN EN ISO 9001:2008 standard.