产品简要
公司名称 :
Dianova
产品类型 :
抗体
产品名称 :
Anti-GFAP (Hu) from Mouse (Clone: IF3)
目录 :
DIA-700-P05
规格 :
500微升
价格 :
167 EUR plus VAT
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
IF3
反应物种 :
人类
应用 :
免疫组化, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
目录代码 :
DIA-700-P05
产品名称 :
Anti-GFAP (Hu) from Mouse (Clone: IF3)
产品类型 :
抗体
宿主物种 :
小鼠
克隆性 :
单克隆
共轭 :
nonconjugated
克隆名称 :
IF3
抗体亚型 :
IgG1
规格 :
500微升
标价 :
167 EUR plus VAT
产品描述 :
GFAP (Glial Fibrillary Acidic Protein) has proved to be the most specific marker for cells of astrocytic origin that distinguishes differentiated astrocytes from other glial cells during the development of the central nervous system. Monoclonal antibodies to GFAP are useful in differentiating primary gliomas from metastatic lesions in the brain and for documenting astrocytic differentiation in tumors outside the CNS.
背景 :
As a 50 kDa intracytoplasmic filamentous protein, GFAP is thought to be important in astrocyte motility and shape by providing structural stability. As a consequence of injury to the human CNS caused by trauma, genetic disorders, or chemicals, GFAP is markly upregulated and astrocytes proliferate. On the other hand, with increasing astrocyte malignancy, a progressive loss of GFAP production has been observed. Consequntly, malignant astrocytomas have fewer tumour cells that stain positively and intensely for GFAP than do less malignant astrocytomas and normal brain specimens. Outside the CNS, GFAP has been demonstrated in Schwann cells, enteric glia cells, salivary gland neoplasms, and metastasizing renal carcinomas. Moreover, GFAP has been detected in epiglottic cartilage, pituicytes, immature oligodendrocytes, papillary meningiomas, and myoepithelial cells of the breast.
别名 :
胶质纤维酸性蛋白
特异性 :
人类GFAP
纯度 :
纯化
防腐剂 :
0.05% NaN3
应用摘要 :
免疫组化-P;IH
更多信息或购买 :
公司信息
Dianova
Warburgstr. 45
D-20354 Hamburg
info@dianova.de
www.dianova.de
49 40 45 06 73 30
公司总部: 德国
Since its foundation in 1982, dianova GmbH provides professionals in Life Sciences with antibodies, immunoassays, and products for molecular biology. More than 30 years of grown expertise give rise to a fundamental knowledge about biochemical applications and a profound understanding of customer needs in research and routine diagnostic laboratories of universities, hospitals and the pharmaceutical industry.
Since its foundation in 1982, dianova GmbH provides professionals in Life Sciences with antibodies, immunoassays, and products for molecular biology. More than 30 years of grown expertise give rise to a fundamental knowledge about biochemical applications and a profound understanding of customer needs in research and routine diagnostic laboratories of universities, hospitals and the pharmaceutical industry.
In addition to distributing Life Science and Diagnostic Products in the German speaking region dianova manufactures and markets a series of antibodies with unique properties on a worldwide basis under the brand of optistain. To this end dianova has successfully established a distribution network in more than 25 countries.
At dianova quality is of paramount importance and subject to strict control. Internal controls and audits are carried out in addition to on-site inspections by independent, external inspection companies. In 2003 the TÜV Rheinland/Berlin/Brandenburg successfully completed the first comprehensive certification process. Since then dianova has been certified pursuant to the international DIN EN ISO 9001:2008 standard.