产品简要
公司名称 :
Dianova
产品类型 :
抗体
产品名称 :
Anti-mutated Calreticulin / CALR (Hu) from Mouse (Clone: CAL2) for FFPE tissue
目录 :
DIA-CAL-250
规格 :
250微升
价格 :
698 EUR plus VAT
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
CAL2
反应物种 :
人类
应用 :
免疫组化, 免疫组化-石蜡切片
更多信息或购买 :
Dianova 产品网页
文章摘录数: 2
参考文献
Stein H, Bob R, Durkop H, Erck C, Kämpfe D, Kvasnicka H, et al. A new monoclonal antibody (CAL2) detects CALRETICULIN mutations in formalin-fixed and paraffin-embedded bone marrow biopsies. Leukemia. 2016;30:131-5 pubmed 出版商
Nomani L, Bodo J, Zhao X, Durkin L, Loghavi S, Hsi E. CAL2 Immunohistochemical Staining Accurately Identifies CALR Mutations in Myeloproliferative Neoplasms. Am J Clin Pathol. 2016;146:431-8 pubmed 出版商
图像
图像 1 :
Dianova DIA-CAL-250 图像 1
Selective staining of mutated CALR protein in megakaryocytes of a PMF case in prefibrotic phase, in which Sanger sequencing detected a CALR mutation.
图像 2 :
Dianova DIA-CAL-250 图像 2
Selective staining of mutated CALR protein in megakaryocytes a PMF case in fibrotic phase, in which Sanger sequencing detected a CALR mutation.
产品信息
目录代码 :
DIA-CAL-250
产品名称 :
Anti-mutated Calreticulin / CALR (Hu) from Mouse (Clone: CAL2) for FFPE tissue
产品类型 :
抗体
宿主物种 :
小鼠
克隆性 :
单克隆
共轭 :
nonconjugated
克隆名称 :
CAL2
抗体亚型 :
IgG2a
规格 :
250微升
标价 :
698 EUR plus VAT
Pubmed号列表 :
26202929;26202929;27686170
产品描述 :
CAL2 labels the megakaryocytes in myeloproliferative neoplasms (essential thrombocythaemia (ET) and primary myelofibrosis (PMF)) with CALR mutation and enables to distinguish ET and PMF with CALR mutation from polycythemia vera (PV), from CALR mutation negative ET and PMF and from reactive bone marrow.
免疫原 :
C-neoterminus of mutated CALR
定位 :
Cytoplasmic
特异性 :
Human CALR protein expressed by all types of Exon 9 CALR mutations (deletion/insertion in 19p 13.3-13.2 of)
纯度 :
纯化
防腐剂 :
0.05% NaN3
应用摘要 :
免疫组化-P;IH
更多信息或购买 :
Dianova 产品网页
公司信息
Dianova
Warburgstr. 45
D-20354 Hamburg
info@dianova.de
www.dianova.de
49 40 45 06 73 30
公司总部: 德国
Since its foundation in 1982, dianova GmbH provides professionals in Life Sciences with antibodies, immunoassays, and products for molecular biology. More than 30 years of grown expertise give rise to a fundamental knowledge about biochemical applications and a profound understanding of customer needs in research and routine diagnostic laboratories of universities, hospitals and the pharmaceutical industry.
Since its foundation in 1982, dianova GmbH provides professionals in Life Sciences with antibodies, immunoassays, and products for molecular biology. More than 30 years of grown expertise give rise to a fundamental knowledge about biochemical applications and a profound understanding of customer needs in research and routine diagnostic laboratories of universities, hospitals and the pharmaceutical industry.
In addition to distributing Life Science and Diagnostic Products in the German speaking region dianova manufactures and markets a series of antibodies with unique properties on a worldwide basis under the brand of optistain. To this end dianova has successfully established a distribution network in more than 25 countries.
At dianova quality is of paramount importance and subject to strict control. Internal controls and audits are carried out in addition to on-site inspections by independent, external inspection companies. In 2003 the TÜV Rheinland/Berlin/Brandenburg successfully completed the first comprehensive certification process. Since then dianova has been certified pursuant to the international DIN EN ISO 9001:2008 standard.