Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

抗体

SC-35抗体, 克隆1SC-4F11

04-1550

100微升

单克隆

小鼠

未共轭

1SC-4F11

Epigenetics & Nuclear Function

抗SC-35抗体, 克隆1SC-4F11

抗体

单克隆抗体

Q01130

小鼠

SC-35

腹水

IgG1κ

抗SC-35抗体, 克隆1SC-4F11

人类;小鼠;大鼠

SC-35 is also known as Splicing factor SC35 and Splicing factor, arginine/serine-rich 2. This protein is encoded by the SFRS2 gene and is a member of the splicing factor SR family. SC-35 is involved in pre-mRNA splicing and is found in bodies in the nucleus that are highly enriched in poly(A) RNA. These nuclear bodies are referred to as speckles, SC 35 domains, or splicing factor compartments (SFCs). The purpose of these bodies is still widely disputed. Speckles correspond largely to, if not entirely to, ultra structures called inter-chromatin granule clusters (IGCs). SC3-35 is required for pre-mRNA splicing events and is highly involved in spliceosomal interaction and assembly. SC-35 is necessary for assembly of the ATP-dependent splicing complex. It is also necessary for the ATP-dependent communication between pre-mRNA and U1 and U2 snRNPs.

Protein PR264;Splicing component, 35 kDa;Splicing factor SC35;splicing factor, arginine/serine-rich 2

Ovalbumin-conjugated linear peptide corresponding to human SC35.

这抗体识别SC35

100微升

免疫印迹;免疫细胞化学

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.