Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

抗体

RNA polymerase II subunit B1 (phospho-CTD Ser-7) Antibody, clone 4E12

04-1570-I

100微升

单克隆

大鼠

未共轭

磷酸化

4E12

人类, 小鼠

Epigenetics & Nuclear Function

Anti-RNA polymerase II subunit B1 (phospho-CTD Ser-7) Antibody, clone 4E12

抗体

单克隆抗体

P24928

大鼠

RNA polymerase II subunit B1 (phospho-CTD Ser-7)

4E12

Culture Supernatant

IgG1κ

Anti-RNA polymerase II subunit B1 (phospho-CTD Ser-7) Antibody, clone 4E12

小鼠;人类

RPB1 (RNA polymerase II subunit B1) is the catalytic component of RNA polymerase II which synthesizes mRNA and non-coding RNAs. During transcription, elongation is influenced by the phosphorylation status of the C-terminal domain (CTD) of RPB1, which acts as an assembly platform for factors regulating transcription initiation, elongation, termination and mRNA processing. Phosphorylation occurs mainly at residues 'Ser-2' and 'Ser-5' of the tandem 7 residue repeats in the C-terminal domain (CTD), which activates Pol II. This phosphorylation also can occur at 'Ser-7' of the heptapepdtide repeat. This antibody recognizes the 'Ser-7' CTD residue of RPB1.

DNA-directed RNA polymerase II subunit RPB1;RNA polymerase II subunit B1;DNA-directed RNA polymerase II subunit A;DNA-directed RNA polymerase III largest subunit;RNA-directed RNA polymerase II subunit RPB1

Ovalbumin-conjugated linear peptide corresponding to human RNA polymerase II subunit B1 phosphorylated at Ser7 of the C-terminal domain (CTD).

This antibody recognizes RNA polymerase II subunit B1 phosphorylated at Ser7 of the C-terminal domain (CTD).

100微升

染色质免疫沉淀 (ChIP);免疫印迹;酶联免疫吸附测定

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.