Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

抗体

磷酸化p53(Ser6)抗体, 克隆Y179, 兔单克隆

04-540

100微升

单克隆

domestic rabbit

未共轭

Y179

Epigenetics & Nuclear Function

抗磷酸化p53(Ser6)抗体, 克隆Y179, 兔单克隆

抗体

单克隆抗体

P04637

兔

磷酸化p53(Ser6)

Y179

Culture Supernatant

IgG

抗磷酸化p53(Ser6)抗体, 克隆Y179, 兔单克隆

人类

The p53 gene is mutated in approximately half of all human cancers. It is involved in the cellular response to cytotoxic stresses, and together with p19ARF, induces expression of p21Cip1, to cause cell cycle arrest. In addition, p53 is able to induce apoptosis, both by transcriptional and non-transcriptional mechanisms. The amino-terminal 83 amino acids of p53 contain the transactivation domain, as well as the region involved in transcription-independent growth suppression. The carboxy-terminal region contains the DNA-binding domain, which is regulated by three phosphorylation events, and potentially by acetylation also.

Antigen NY-CO-13 ;Phosphoprotein p53 ;Tumor suppressor p53 ;p53 antigen;p53 transformation suppressor;p53 tumor suppressor ;transformation-related protein 53;tumor protein p53

KLH conjugated linear peptide corresponding to Phospho p53.

这抗体识别磷酸化p53(Ser6)

100微升

免疫印迹;免疫细胞化学;免疫组化;免疫沉淀

Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.