This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
默克密理博中国
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
产品类型 :
抗体
产品名称 :
Akt1/PKBα抗体, 克隆AW24, 兔单克隆
目录 :
04-796
规格 :
100微升
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
AW24
反应物种 :
人类, 小鼠, 大鼠
文章摘录数: 8
参考文献
González Hedström D, Amor S, de la Fuente Fernández M, Tejera Muñoz A, Priego T, Martín A, et al. A Mixture of Algae and Extra Virgin Olive Oils Attenuates the Cardiometabolic Alterations Associated with Aging in Male Wistar Rats. Antioxidants (Basel). 2020;9: pubmed 出版商
de la Fuente Fernández M, González Hedström D, Amor S, Tejera Muñoz A, Fernandez N, Monge L, et al. Supplementation with a Carob (Ceratonia siliqua L.) Fruit Extract Attenuates the Cardiometabolic Alterations Associated with Metabolic Syndrome in Mice. Antioxidants (Basel). 2020;9: pubmed 出版商
Cheng H, Liang Y, Kuo Y, Chuu C, Lin C, Lee M, et al. Identification of thioridazine, an antipsychotic drug, as an antiglioblastoma and anticancer stem cell agent using public gene expression data. Cell Death Dis. 2015;6:e1753 pubmed 出版商
Iacovides D, Johnson A, Wang N, Boddapati S, Korkola J, Gray J. Identification and quantification of AKT isoforms and phosphoforms in breast cancer using a novel nanofluidic immunoassay. Mol Cell Proteomics. 2013;12:3210-20 pubmed 出版商
Moore S, van den Bosch M, Hunter R, Sakamoto K, Poole A, Hers I. Dual regulation of glycogen synthase kinase 3 (GSK3)?/? by protein kinase C (PKC)? and Akt promotes thrombin-mediated integrin ?IIb?3 activation and granule secretion in platelets. J Biol Chem. 2013;288:3918-28 pubmed 出版商
Lu X, Tompkins R, Fischman A. SILAM for quantitative proteomics of liver Akt1/PKB? after burn injury. Int J Mol Med. 2012;29:461-71 pubmed 出版商
Siepmann M, Kumar S, Mayer G, Walter J. Casein kinase 2 dependent phosphorylation of neprilysin regulates receptor tyrosine kinase signaling to Akt. PLoS ONE. 2010;5: pubmed 出版商
Keeshan K, Bailis W, Dedhia P, Vega M, Shestova O, Xu L, et al. Transformation by Tribbles homolog 2 (Trib2) requires both the Trib2 kinase domain and COP1 binding. Blood. 2010;116:4948-57 pubmed 出版商
产品信息
目录代码 :
04-796
亚类别 :
Cell Signaling
产品名称 :
抗Akt1/PKBα抗体, 克隆AW24, 兔单克隆
产品类型 :
抗体
克隆性 :
单克隆抗体
基因编号 :
P31749
宿主名称 :
兔
抗原 :
Akt1/PKBα
克隆 :
AW24
抗体亚型 :
IgG
产品描述 :
抗Akt1/PKBα抗体, 克隆AW24, 兔单克隆
交叉活性 :
人类;小鼠;大鼠
背景 :
The serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific. In the developing nervous system AKT is a critical mediator of growth factor induced neuronal survival. Survival factors can suppress apoptosis in a transcription independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene.
别名 :
AKT1 kinase;Protein kinase B;RAC-alpha serine/threonine-protein kinase;rac protein kinase alpha;v-akt murine thymoma viral oncogene homolog 1
免疫原 :
Sythetic peptide (C-RPHFPQFSYSASGTA) corresponding to the C-terminal (residues 466-480) of rat Akt1/PKBα.
特异性 :
这抗体识别Akt1/PKBα
包装尺寸 :
100微升
用途 :
免疫印迹;免疫沉淀
储存 :
Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
公司信息
默克密理博中国
上海市浦东张江高科技园区晨晖路88号2号楼2楼
asiatechserv@millipore.com
http://www.millipore.com/china/wwcn/cnhome
400-889-1988
公司总部: 美国
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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