This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
默克密理博中国
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
产品类型 :
抗体
产品名称 :
Histone H4 Antibody, pan, rabbit monoclonal
目录 :
04-858
规格 :
100微升
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
62-141-13
反应物种 :
人类, 小鼠, brewer's yeast
应用 :
免疫印迹, 染色质免疫沉淀
文章摘录数: 19
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; brewer's yeast; 图 s1e
Yu R, Sun L, Sun Y, Han X, Qin L, Dang W. Cellular response to moderate chromatin architectural defects promotes longevity. Sci Adv. 2019;5:eaav1165 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Huichalaf C, Micheloni S, Ferri G, Caccia R, Gabellini D. DNA methylation analysis of the macrosatellite repeat associated with FSHD muscular dystrophy at single nucleotide level. PLoS ONE. 2014;9:e115278 pubmed 出版商
  • 免疫印迹; 人类; 1:10000
Dudakovic A, Camilleri E, Lewallen E, McGee Lawrence M, Riester S, Kakar S, et al. Histone deacetylase inhibition destabilizes the multi-potent state of uncommitted adipose-derived mesenchymal stromal cells. J Cell Physiol. 2015;230:52-62 pubmed 出版商
  • 免疫印迹; 人类
Mücke K, Paulus C, Bernhardt K, Gerrer K, Schön K, Fink A, et al. Human cytomegalovirus major immediate early 1 protein targets host chromosomes by docking to the acidic pocket on the nucleosome surface. J Virol. 2014;88:1228-48 pubmed 出版商
  • 免疫印迹; 小鼠
Schroeder F, Lewis M, Fass D, Wagner F, Zhang Y, Hennig K, et al. A selective HDAC 1/2 inhibitor modulates chromatin and gene expression in brain and alters mouse behavior in two mood-related tests. PLoS ONE. 2013;8:e71323 pubmed 出版商
  • 免疫印迹; 小鼠
Londoño Gentile T, Lu C, Lodato P, Tse S, Olejniczak S, Witze E, et al. DNMT1 is regulated by ATP-citrate lyase and maintains methylation patterns during adipocyte differentiation. Mol Cell Biol. 2013;33:3864-78 pubmed 出版商
  • 免疫印迹; 人类
  • 免疫印迹; 小鼠
Brochier C, Dennis G, Rivieccio M, McLaughlin K, Coppola G, Ratan R, et al. Specific acetylation of p53 by HDAC inhibition prevents DNA damage-induced apoptosis in neurons. J Neurosci. 2013;33:8621-32 pubmed 出版商
de Bruyn Kops A, Burke J, Guthrie C. Brr6 plays a role in gene recruitment and transcriptional regulation at the nuclear envelope. Mol Biol Cell. 2018;29:2578-2590 pubmed 出版商
Wang Y, Zhang J, Wu L, Liu W, Wei G, Gong X, et al. Tricho-rhino-phalangeal syndrome 1 protein functions as a scaffold required for ubiquitin-specific protease 4-directed histone deacetylase 2 de-ubiquitination and tumor growth. Breast Cancer Res. 2018;20:83 pubmed 出版商
Mo X, Zhang H, Preston S, Martin K, Zhou B, Vadalia N, et al. Interferon-γ Signaling in Melanocytes and Melanoma Cells Regulates Expression of CTLA-4. Cancer Res. 2018;78:436-450 pubmed 出版商
Dmitriev R, Papkovsky D. In vitro ischemia decreases histone H4K16 acetylation in neural cells. FEBS Lett. 2015;589:138-44 pubmed 出版商
Trécul A, Morceau F, Gaigneaux A, Schnekenburger M, Dicato M, Diederich M. Valproic acid regulates erythro-megakaryocytic differentiation through the modulation of transcription factors and microRNA regulatory micro-networks. Biochem Pharmacol. 2014;92:299-311 pubmed 出版商
Dmitriev R, Pestov N, Shakhparonov M, Okkelman I. Two distinct nuclear localization signals in mammalian MSL1 regulate its function. J Cell Biochem. 2014;115:1967-73 pubmed 出版商
Khair L, Guikema J, Linehan E, Ucher A, Leus N, Ogilvie C, et al. ATM increases activation-induced cytidine deaminase activity at downstream S regions during class-switch recombination. J Immunol. 2014;192:4887-96 pubmed 出版商
Gaglio D, D Alfonso A, Camilloni G. Functional complementation of sir2? yeast mutation by the human orthologous gene SIRT1. PLoS ONE. 2013;8:e83114 pubmed 出版商
Schiza V, Molina Serrano D, Kyriakou D, Hadjiantoniou A, Kirmizis A. N-alpha-terminal acetylation of histone H4 regulates arginine methylation and ribosomal DNA silencing. PLoS Genet. 2013;9:e1003805 pubmed 出版商
Komatsu T, Nagata K. Replication-uncoupled histone deposition during adenovirus DNA replication. J Virol. 2012;86:6701-11 pubmed 出版商
Mishra P, Au W, Choy J, Kuich P, Baker R, Foltz D, et al. Misregulation of Scm3p/HJURP causes chromosome instability in Saccharomyces cerevisiae and human cells. PLoS Genet. 2011;7:e1002303 pubmed 出版商
Revenko A, Kalashnikova E, Gemo A, Zou J, Chen H. Chromatin loading of E2F-MLL complex by cancer-associated coregulator ANCCA via reading a specific histone mark. Mol Cell Biol. 2010;30:5260-72 pubmed 出版商
产品信息
目录代码 :
04-858
亚类别 :
Epigenetics & Nuclear Function
产品名称 :
Anti-Histone H4 Antibody, pan, rabbit monoclonal
产品类型 :
抗体
克隆性 :
单克隆抗体
基因编号 :
P62805
宿主名称 :
兔
抗原 :
组蛋白H4
克隆 :
62-141-13
共轭标签 :
Culture Supernatant
抗体亚型 :
IgG
产品描述 :
Anti-Histone H4 Antibody, pan, rabbit monoclonal
交叉活性 :
Chicken;Human;Vertebrates;Yeast ( S. cerevisiae )
背景 :
Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The histones have an amino terminal tail, a globular domain, and a carboxy-terminal tail. The four core histones, H2A, H2B, H3 and H4 assemble into the octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped in a sequence-independent manner around the octamer, forming the basic subunit of chromatin, the nucleosome. Histone H4 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail, H4 is involved with the structure of the nucleosomes of the 'beads on a string' structure.
别名 :
H4;组蛋白H4
免疫原 :
Synthetic peptide corresponding to amino acids 17-28 of Histone H4. Epitope has been mapped to residues 25-28
特异性 :
识别组蛋白H4
包装尺寸 :
100微升
用途 :
Western Blotting;Multiplexing;Chromatin Immunoprecipitation (ChIP)
储存 :
Stable for 1 year at -20°C from date of receipt. For maximum recovery of product, centrifuge the vial prior to removing the cap. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
公司信息
默克密理博中国
上海市浦东张江高科技园区晨晖路88号2号楼2楼
asiatechserv@millipore.com
http://www.millipore.com/china/wwcn/cnhome
400-889-1988
公司总部: 美国
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

Hundreds of New Antibodies in the areas of:
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View all the new antibodies at www.emdmillipore.com.