This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
默克密理博中国
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
产品类型 :
抗体
产品名称 :
HDAC1抗体, 克隆2E10
目录 :
05-100
规格 :
100微升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
2E10
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫沉淀, 染色质免疫沉淀 , 免疫印迹基因敲除验证
文章摘录数: 37
出版应用/物种/样本/稀释参考文献
  • 免疫沉淀; 人类; 图 1
  • 免疫印迹; 人类; 图 1
Citro S, Chiocca S. Assessing the Role of Paralog-Specific Sumoylation of HDAC1. Methods Mol Biol. 2017;1510:329-337 pubmed
  • 免疫印迹; 小鼠; 图 6
Ow J, Palanichamy Kala M, Rao V, Choi M, Bharathy N, Taneja R. G9a inhibits MEF2C activity to control sarcomere assembly. Sci Rep. 2016;6:34163 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s1
Pinz S, Unser S, Rascle A. Signal transducer and activator of transcription STAT5 is recruited to c-Myc super-enhancer. BMC Mol Biol. 2016;17:10 pubmed 出版商
  • 免疫印迹; 人类; 图 s1
Sakurai T, Isogaya K, Sakai S, Morikawa M, Morishita Y, Ehata S, et al. RNA-binding motif protein 47 inhibits Nrf2 activity to suppress tumor growth in lung adenocarcinoma. Oncogene. 2016;35:5000-9 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 1:1000; 图 s1
Kwon D, Eom G, Ko J, Shin S, Joung H, Choe N, et al. MDM2 E3 ligase-mediated ubiquitination and degradation of HDAC1 in vascular calcification. Nat Commun. 2016;7:10492 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠; 图 3
Wilson C, Jurk D, Fullard N, Banks P, Page A, Luli S, et al. NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma. Nat Commun. 2015;6:6818 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
  • 免疫印迹; 人类
Pinz S, Unser S, Buob D, Fischer P, Jobst B, Rascle A. Deacetylase inhibitors repress STAT5-mediated transcription by interfering with bromodomain and extra-terminal (BET) protein function. Nucleic Acids Res. 2015;43:3524-45 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Hennig D, Müller S, Wichmann C, Drube S, Pietschmann K, Pelzl L, et al. Antagonism between granulocytic maturation and deacetylase inhibitor-induced apoptosis in acute promyelocytic leukaemia cells. Br J Cancer. 2015;112:329-37 pubmed 出版商
  • 免疫印迹; 人类
Isogaya K, Koinuma D, Tsutsumi S, Saito R, Miyazawa K, Aburatani H, et al. A Smad3 and TTF-1/NKX2-1 complex regulates Smad4-independent gene expression. Cell Res. 2014;24:994-1008 pubmed 出版商
  • 免疫印迹; 小鼠
Conradt L, Henrich A, Wirth M, Reichert M, Lesina M, Algül H, et al. Mdm2 inhibitors synergize with topoisomerase II inhibitors to induce p53-independent pancreatic cancer cell death. Int J Cancer. 2013;132:2248-57 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
  • 免疫印迹; 人类
Karius T, Schnekenburger M, Ghelfi J, Walter J, Dicato M, Diederich M. Reversible epigenetic fingerprint-mediated glutathione-S-transferase P1 gene silencing in human leukemia cell lines. Biochem Pharmacol. 2011;81:1329-42 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
  • 免疫印迹; 人类
Milagre I, Nunes M, Moutinho M, Rivera I, Fuso A, Scarpa S, et al. Chromatin-modifying agents increase transcription of CYP46A1, a key player in brain cholesterol elimination. J Alzheimers Dis. 2010;22:1209-21 pubmed 出版商
Kawasaki N, Isogaya K, Dan S, Yamori T, Takano H, Yao R, et al. TUFT1 interacts with RABGAP1 and regulates mTORC1 signaling. Cell Discov. 2018;4:1 pubmed 出版商
Clift D, McEwan W, Labzin L, Konieczny V, Mogessie B, James L, et al. A Method for the Acute and Rapid Degradation of Endogenous Proteins. Cell. 2017;171:1692-1706.e18 pubmed 出版商
Gao Y, Westfield G, Erickson J, Cerione R, Skiniotis G, Ramachandran S. Isolation and structure-function characterization of a signaling-active rhodopsin-G protein complex. J Biol Chem. 2017;292:14280-14289 pubmed 出版商
Gonzalez Lizarraga F, Socias S, Avila C, Torres Bugeau C, Barbosa L, Binolfi A, et al. Repurposing doxycycline for synucleinopathies: remodelling of α-synuclein oligomers towards non-toxic parallel beta-sheet structured species. Sci Rep. 2017;7:41755 pubmed 出版商
Kadiyala V, Patrick N, Mathieu W, Jaime Frias R, Pookhao N, An L, et al. Class I lysine deacetylases facilitate glucocorticoid-induced transcription. J Biol Chem. 2013;288:28900-12 pubmed 出版商
Bigley T, Reitsma J, Mirza S, Terhune S. Human cytomegalovirus pUL97 regulates the viral major immediate early promoter by phosphorylation-mediated disruption of histone deacetylase 1 binding. J Virol. 2013;87:7393-408 pubmed 出版商
Mounce B, Mboko W, Bigley T, Terhune S, Tarakanova V. A conserved gammaherpesvirus protein kinase targets histone deacetylases 1 and 2 to facilitate viral replication in primary macrophages. J Virol. 2013;87:7314-25 pubmed 出版商
Rudra D, deRoos P, Chaudhry A, Niec R, Arvey A, Samstein R, et al. Transcription factor Foxp3 and its protein partners form a complex regulatory network. Nat Immunol. 2012;13:1010-9 pubmed 出版商
Gantner B, Jin H, Qian F, Hay N, He B, Ye R. The Akt1 isoform is required for optimal IFN-β transcription through direct phosphorylation of β-catenin. J Immunol. 2012;189:3104-11 pubmed 出版商
Parolin C, Calonghi N, Presta E, Boga C, Caruana P, Naldi M, et al. Mechanism and stereoselectivity of HDAC I inhibition by (R)-9-hydroxystearic acid in colon cancer. Biochim Biophys Acta. 2012;1821:1334-40 pubmed 出版商
Pacheco M, Nielsen T. Histone deacetylase 1 and 2 in mesenchymal tumors. Mod Pathol. 2012;25:222-30 pubmed 出版商
Morikawa M, Koinuma D, Tsutsumi S, Vasilaki E, Kanki Y, Heldin C, et al. ChIP-seq reveals cell type-specific binding patterns of BMP-specific Smads and a novel binding motif. Nucleic Acids Res. 2011;39:8712-27 pubmed 出版商
Guo H, Friedman A. Phosphorylation of RUNX1 by cyclin-dependent kinase reduces direct interaction with HDAC1 and HDAC3. J Biol Chem. 2011;286:208-15 pubmed 出版商
Waby J, Chirakkal H, Yu C, Griffiths G, Benson R, Bingle C, et al. Sp1 acetylation is associated with loss of DNA binding at promoters associated with cell cycle arrest and cell death in a colon cell line. Mol Cancer. 2010;9:275 pubmed 出版商
Godmann M, May E, Kimmins S. Epigenetic mechanisms regulate stem cell expressed genes Pou5f1 and Gfra1 in a male germ cell line. PLoS ONE. 2010;5:e12727 pubmed 出版商
Bhandari D, Seo K, Jung J, Kim H, Yang S, Kang K. The regulatory role of c-MYC on HDAC2 and PcG expression in human multipotent stem cells. J Cell Mol Med. 2011;15:1603-14 pubmed 出版商
Warrener R, Chia K, Warren W, Brooks K, Gabrielli B. Inhibition of histone deacetylase 3 produces mitotic defects independent of alterations in histone H3 lysine 9 acetylation and methylation. Mol Pharmacol. 2010;78:384-93 pubmed 出版商
von Burstin J, Eser S, Paul M, Seidler B, Brandl M, Messer M, et al. E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex. Gastroenterology. 2009;137:361-71, 371.e1-5 pubmed 出版商
Kajiwara Y, Akram A, Katsel P, Haroutunian V, Schmeidler J, Beecham G, et al. FE65 binds Teashirt, inhibiting expression of the primate-specific caspase-4. PLoS ONE. 2009;4:e5071 pubmed 出版商
Ashe A, Morgan D, Whitelaw N, Bruxner T, Vickaryous N, Cox L, et al. A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development. Genome Biol. 2008;9:R182 pubmed 出版商
Stolt C, Lommes P, Hillgärtner S, Wegner M. The transcription factor Sox5 modulates Sox10 function during melanocyte development. Nucleic Acids Res. 2008;36:5427-40 pubmed 出版商
Iwamoto F, Stadler M, Chalupníková K, Oakeley E, Nagamine Y. Transcription-dependent nucleolar cap localization and possible nuclear function of DExH RNA helicase RHAU. Exp Cell Res. 2008;314:1378-91 pubmed 出版商
Le May N, Mansuroglu Z, Léger P, Josse T, Blot G, Billecocq A, et al. A SAP30 complex inhibits IFN-beta expression in Rift Valley fever virus infected cells. PLoS Pathog. 2008;4:e13 pubmed 出版商
Diaz Martinez L, Giménez Abián J, Clarke D. Regulation of centromeric cohesion by sororin independently of the APC/C. Cell Cycle. 2007;6:714-24 pubmed
Simonsson M, Heldin C, Ericsson J, Grönroos E. The balance between acetylation and deacetylation controls Smad7 stability. J Biol Chem. 2005;280:21797-803 pubmed
产品信息
目录代码 :
05-100
亚类别 :
Cell Signaling
产品名称 :
抗HDAC1抗体, 克隆2E10
产品类型 :
抗体
克隆性 :
单克隆抗体
基因编号 :
Q13547
宿主名称 :
小鼠
抗原 :
HDAC1
克隆 :
2E10
共轭标签 :
Culture Supernatant
抗体亚型 :
IgG1
产品描述 :
抗HDAC1抗体, 克隆2E10
交叉活性 :
人类;小鼠
免疫原 :
KLH-conjugated, synthetic peptide (C-EEKPEAKGVKEEVKLA) corresponding to amino acids 467-482 of mouse HDAC1. The immunizing sequence is identical in human.
特异性 :
HDAC-1
包装尺寸 :
100微升
用途 :
免疫沉淀;免疫印迹
储存 :
2 years at -20°C from date of shipment.
公司信息
默克密理博中国
上海市浦东张江高科技园区晨晖路88号2号楼2楼
asiatechserv@millipore.com
http://www.millipore.com/china/wwcn/cnhome
400-889-1988
公司总部: 美国
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

Hundreds of New Antibodies in the areas of:
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  • • Cardiovascular Disease
  • • Developmental Biology
  • • Metabolic Disease
  • • Neurodegenerative Disease
  • • Cell Biology
View all the new antibodies at www.emdmillipore.com.