Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

抗体

磷酸化p38α(Thr180/Tyr182)抗体, 克隆8.78.8, 兔单克隆

05-1059

100微升

单克隆

domestic rabbit

未共轭

8.78.8

人类, 小鼠

Cell Signaling

抗磷酸化p38α(Thr180/Tyr182)抗体, 克隆8.78.8, 兔单克隆

抗体

单克隆抗体

Q15759

兔

磷酸化p38α(Thr180/Tyr182)

8.78.8

Culture Supernatant

IgG

抗磷酸化p38α(Thr180/Tyr182)抗体, 克隆8.78.8, 兔单克隆

人类;小鼠;脊椎动物

The p38 family refers to the SAPK2/3 Kinases (Stess-Activated Protein Kinases), a subfamily of JNK/SAPK family. p38/SAPK Kinases are also activated by stresses, most notably inflammatory cytokines, irradiation, and certain toxins such as anisomycin and arsenite. SAPKs have been implicated in many pathological conditions, including inflammation, cancer and neurodegenerative diseases. As with the other MAPK family members (ERK, JNK, p38MAPK, and ERK5), p38 is activated through phosphorylation on both threonine and tyrosine residues at the Thr-X-Tyr dual phosphorylation motif, where X is Gly for p38. Once phosphorylated and active, it then goes on to phosphorylate downstream targets in both the cytoplasm and the nucleus. Some of their main targets of p38 are the kinase MAPKAPK2 and the transcription factor ATF2 that are activated via their phosphorylation.

CSAID-binding protein;Csaids binding protein ;Cytokine suppressive anti-inflammatory drug-binding protein ;MAP kinase MXI2;MAP kinase p38 alpha;MAX-interacting protein 2;Mitogen-activated protein kinase p38 alpha ;cytokine suppressive anti-inflammatory drug binding protein;mitogen-activated protein kinase 14;p38 MAP kinase;p38 mitogen activated protein kinase;p38alpha Exip ;stress-activated protein kinase 2A

Synthetic peptide corresponding to amino acids surrounding and including phosphorylated Thr180/Tyr182 of human p38α.

This antibody detects p38α when phosphorylated on Thr180/Tyr182.

100微升

免疫印迹;免疫荧光

Stable for 1 year at -20ºC from date of receipt.