This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
默克密理博中国
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
产品类型 :
抗体
产品名称 :
CD45抗体, 克隆F10-89
目录 :
05-1410
规格 :
100微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
F10-89-4

同一抗体克隆可从以下厂商购到:
反应物种 :
人类, 小鼠
产品信息
目录代码 :
05-1410
亚类别 :
Cell Signaling
产品名称 :
抗CD45抗体, 克隆F10-89
产品类型 :
抗体
克隆性 :
单克隆抗体
基因编号 :
P08575
宿主名称 :
小鼠
抗原 :
CD45
克隆 :
F10-89-4
共轭标签 :
亲和纯化
抗体亚型 :
IgG2a
产品描述 :
抗CD45抗体, 克隆F10-89
交叉活性 :
人类;小鼠;大鼠
背景 :
CD45 is a receptor-tyrosine phosphatase required for antigen-induced signaling in T-cells and B-cells; its substrates are unknown. Interestingly, it associates with several Src-family tyrosine kinases, which are inhibited by tyrosine phosphorylation in their c-termini, suggesting a mechanism for signaling by CD45.
别名 :
CD45 antigen;Leukocyte common antigen precursor;SCID due to PTPRC deficiency;T200 glycoprotein;T200 leukocyte common antigen;Human homolog of severe combined immunodeficiency due to PTPRC deficiency;Leukocyte-common antigen;Protein tyrosine phosphatase, receptor type, C;Protein tyrosine phosphatase, receptor type, c polypeptide
免疫原 :
纯化T细胞来自人类淋巴结
特异性 :
This antibody reacts with the leucocyte common antigen (LCA) complex to be found on lymphocytes, monocytes, granulocytes, thymocytes and malignant T and B cells. No reactivity has been observed with primary or metastatic carcinoma cells. Plasma cells or myeloma cells may have weak expression or be negative for this antigen. The LCA comprises of at least 5 isoforms ranging from 180-220 kDa which are produced as a result of alternative splicing of exons A, B or C. CBL 124 recognizes epitopes common to all of the isoforms. Antigen distribution: Thymocytes 95% Granulocytes 95% Monocytes 95% B cells (CD20+) 95% T cells (CD3+) 95% NK cells (CD16+) 95% Peripheral blood lymphocytes 95% FUSION PARTNER: NS1 myeloma cell line
包装尺寸 :
100微克
用途 :
流式细胞仪;免疫印迹;免疫荧光;免疫沉淀;免疫组化(石蜡)
储存 :
For use within 1 month of purchase store at 2-8°C, for long term storage aliquot antibody into small volumes and store at -20°C for up to one year from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
公司信息
默克密理博中国
上海市浦东张江高科技园区晨晖路88号2号楼2楼
asiatechserv@millipore.com
http://www.millipore.com/china/wwcn/cnhome
400-889-1988
公司总部: 美国
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

Hundreds of New Antibodies in the areas of:
  • • Cancer
  • • Nuclear Signaling
  • • Apoptosis
  • • Cardiovascular Disease
  • • Developmental Biology
  • • Metabolic Disease
  • • Neurodegenerative Disease
  • • Cell Biology
View all the new antibodies at www.emdmillipore.com.