Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

抗体

runt相关转录因子2抗体, 克隆AS110

05-1478

100微克

单克隆

小鼠

未共轭

AS110

Epigenetics & Nuclear Function

抗runt相关转录因子2抗体, 克隆AS110

抗体

单克隆抗体

Q13950

小鼠

runt相关转录因子2

AS110

纯化

IgG2b

抗runt相关转录因子2抗体, 克隆AS110

人类

RUNX2 (Runt-related transcription Factor) is a transcription factor that binds to its canonical consensus sequence 5’- PYGPYGGT-3’ in a number of promoters and enhancers. They include LCK, T-cell receptor enhancers, and various bone related genes such as osteocalcin, osteopontin, and bone sialoprotein. As a result of this, RUNX2 is involved in osteoblastic differentiation and skeletal morphogenesis. RUNX2 contains a proline/serine/ threonine-rich region at its C-terminus that has shown to be critical for its transcriptional activity.

Acute myeloid leukemia 3 protein;CBF-alpha 1;Core-binding factor subunit alpha-1;Oncogene AML-3 ;Osteoblast-specific transcription factor 2 ;PEA2-alpha A;PEBP2-alpha A ;Polyomavirus enhancer-binding protein 2 alpha A subunit;SL3-3 enhancer factor 1 alpha A subunit;SL3/AKV core-binding factor alpha A subunit;core-binding factor, runt domain, alpha subunit 1;polyomavirus enhancer binding protein 2 alpha A subunit ;runt-related transcription factor 2

GST-coupled recombinant protein corresponding to amino acids 311-415 of human RUNX2.

Detects RUNX2

100微克

免疫印迹;免疫细胞化学

Stable for 1 year at 2-8°C from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution.