This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
默克密理博中国
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
产品类型 :
抗体
产品名称 :
核不均一核糖核蛋白A1抗体, 克隆4B10
目录 :
05-1521
规格 :
100微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
4B10
文章摘录数: 4
参考文献
Libner C, Salapa H, Hutchinson C, Lee S, Levin M. Antibodies to the RNA binding protein heterogeneous nuclear ribonucleoprotein A1 contribute to neuronal cell loss in an animal model of multiple sclerosis. J Comp Neurol. 2020;528:1704-1724 pubmed 出版商
Collier S, Henderson M, Tossberg J, Aune T. Regulation of the Th1 genomic locus from Ifng through Tmevpg1 by T-bet. J Immunol. 2014;193:3959-65 pubmed 出版商
Pham D, Vincentz J, Firulli A, Kaplan M. Twist1 regulates Ifng expression in Th1 cells by interfering with Runx3 function. J Immunol. 2012;189:832-40 pubmed 出版商
Ziaei S, Shimada N, Kucharavy H, Hubbard K. MNK1 expression increases during cellular senescence and modulates the subcellular localization of hnRNP A1. Exp Cell Res. 2012;318:500-8 pubmed 出版商
产品信息
目录代码 :
05-1521
亚类别 :
Epigenetics & Nuclear Function
产品名称 :
抗核不均一核糖核蛋白A1抗体, 克隆4B10
产品类型 :
抗体
克隆性 :
单克隆抗体
基因编号 :
P09651
宿主名称 :
小鼠
抗原 :
核不均一核糖核蛋白A1
克隆 :
4B10
共轭标签 :
纯化
抗体亚型 :
IgG2bκ
产品描述 :
抗核不均一核糖核蛋白A1抗体, 克隆4B10
交叉活性 :
人类
背景 :
The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and associate with pre-mRNAs in the nucleus. These complexes are associated with pre-mRNA processing and other aspects of mRNA metabolism and transport. While all hnRNPs are present in the nucleus, data suggests they shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by hnRNP A1 has two repeats of quasi-RRM domains that bind to RNAs. This abundant core protein, along with other hnRNP proteins, is exported from the nucleus, probably bound to mRNA, and is immediately re-imported. The hnRNP A1 protein is involved in the packaging of pre-mRNA into hnRNP particles, transport of poly A+ mRNA from the nucleus to the cytoplasm, and may have a role in splice site selection.
别名 :
Helix-destabilizing protein;Single-strand RNA-binding protein;heterogeneous nuclear ribonucleoprotein A1;heterogeneous nuclear ribonucleoprotein A1B protein;heterogeneous nuclear ribonucleoprotein B2 protein;heterogeneous nuclear ribonucleoprotein core protein A1;hnRNP core protein A1;nuclear ribonucleoprotein particle A1 protein;single-strand DNA-binding protein UP1
免疫原 :
Full length native protein partially purified human hnRNP A1.
特异性 :
这抗体识别核不均一核糖核蛋白A1
包装尺寸 :
100微克
用途 :
西方墨点法
储存 :
收到之日起在2-8℃稳定1年
公司信息
默克密理博中国
上海市浦东张江高科技园区晨晖路88号2号楼2楼
asiatechserv@millipore.com
http://www.millipore.com/china/wwcn/cnhome
400-889-1988
公司总部: 美国
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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