This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
默克密理博中国
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
产品类型 :
抗体
产品名称 :
磷脂酰肌醇(-3)激酶抗体, p85, N-SH3, 克隆AB6
目录 :
05-212
规格 :
100微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
AB6
产品信息
目录代码 :
05-212
亚类别 :
Cell Signaling
产品名称 :
抗磷脂酰肌醇(-3)激酶抗体, p85, N-SH3, 克隆AB6
产品类型 :
抗体
克隆性 :
单克隆抗体
基因编号 :
P27986
宿主名称 :
小鼠
抗原 :
磷脂酰肌醇(-3)激酶
克隆 :
AB6
共轭标签 :
纯化
抗体亚型 :
IgG1κ
产品描述 :
抗磷脂酰肌醇(-3)激酶抗体, p85, N-SH3, 克隆AB6
交叉活性 :
人类;小鼠;大鼠
背景 :
The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that is thought to phosphorylate second messengers in growth signaling pathways. PI3K exists as a heterodimer of catalytic 110 kDa (p110) and regulatory 85 kDa (p85, p50 or p55) subunits. The p85 unit consists of two closely related proteins: p85 alpha, which binds tightly to the catalytic subunit and p85 beta, a protein of unknown function. They share 62% amino acid sequence identity. p85 alpha lacks PI3 kinase activity, but may serve as regulator of the catalytic subunit, p110, by acting as the link between PI3K and the ligand activated receptor. Both isoforms bind to activated receptors and serve as tyrosine kinase substrates.
别名 :
PI3-kinase p85 subunit alpha;PtdIns-3-kinase p85-alpha;phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha);phosphatidylinositol 3-kinase, regulatory, 1;phosphatidylinositol 3-kinase-associated p-85 alpha;phosphoinositide-3-kinase, regulatory subunit 1 (alpha);phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha);phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
免疫原 :
重组人类p85甲磷脂酰肌醇(-3)激酶在大肠杆菌中表达。 克隆AB6
特异性 :
This antibody recognizes p85 alpha subunit of PI3 Kinase; does not recognize p85 beta subunit.
包装尺寸 :
100微克
用途 :
免疫细胞化学;免疫沉淀;免疫印迹
储存 :
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20ºC. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20ºC may cause glycerol-containing solutions to become frozen during storage.
公司信息
默克密理博中国
上海市浦东张江高科技园区晨晖路88号2号楼2楼
asiatechserv@millipore.com
http://www.millipore.com/china/wwcn/cnhome
400-889-1988
公司总部: 美国
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