This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
默克密理博中国
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
产品类型 :
抗体
产品名称 :
细胞周期蛋白B1抗体, 克隆GNS3(8A5D12)
目录 :
05-373
规格 :
200微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
GNS3
反应物种 :
人类, 小鼠
应用 :
免疫印迹
文章摘录数: 14
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠
Adeyemi R, Pintel D. Parvovirus-induced depletion of cyclin B1 prevents mitotic entry of infected cells. PLoS Pathog. 2014;10:e1003891 pubmed 出版商
Lee J, Sung J, Choi E, Yoon H, Kang B, Hong E, et al. C/EBPβ Is a Transcriptional Regulator of Wee1 at the G₂/M Phase of the Cell Cycle. Cells. 2019;8: pubmed 出版商
Fuller M, Majumder K, Pintel D. Minute Virus of Mice Inhibits Transcription of the Cyclin B1 Gene during Infection. J Virol. 2017;91: pubmed 出版商
Cundell M, Hutter L, Nunes Bastos R, Poser E, Holder J, Mohammed S, et al. A PP2A-B55 recognition signal controls substrate dephosphorylation kinetics during mitotic exit. J Cell Biol. 2016;214:539-54 pubmed 出版商
Mukherjee S, Chakraborty P, Saha P. Phosphorylation of Ku70 subunit by cell cycle kinases modulates the replication related function of Ku heterodimer. Nucleic Acids Res. 2016;44:7755-65 pubmed 出版商
Iimori M, Watanabe S, Kiyonari S, Matsuoka K, Sakasai R, Saeki H, et al. Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability. Nat Commun. 2016;7:11117 pubmed 出版商
Seidel C, Schnekenburger M, Mazumder A, Teiten M, Kirsch G, Dicato M, et al. 4-Hydroxybenzoic acid derivatives as HDAC6-specific inhibitors modulating microtubular structure and HSP90α chaperone activity against prostate cancer. Biochem Pharmacol. 2016;99:31-52 pubmed 出版商
Bastos R, Cundell M, Barr F. KIF4A and PP2A-B56 form a spatially restricted feedback loop opposing Aurora B at the anaphase central spindle. J Cell Biol. 2014;207:683-93 pubmed 出版商
Saha J, Wang M, Cucinotta F. Investigation of switch from ATM to ATR signaling at the sites of DNA damage induced by low and high LET radiation. DNA Repair (Amst). 2013;12:1143-51 pubmed 出版商
Yajima H, Fujisawa H, Nakajima N, Hirakawa H, Jeggo P, Okayasu R, et al. The complexity of DNA double strand breaks is a critical factor enhancing end-resection. DNA Repair (Amst). 2013;12:936-46 pubmed 出版商
Ishitsuka Y, Kawachi Y, Maruyama H, Taguchi S, Fujisawa Y, Furuta J, et al. Pituitary tumor transforming gene 1 induces tumor necrosis factor-? production from keratinocytes: implication for involvement in the pathophysiology of psoriasis. J Invest Dermatol. 2013;133:2566-2575 pubmed 出版商
Al Dhaheri Y, Eid A, Abuqamar S, Attoub S, Khasawneh M, Aiche G, et al. Mitotic arrest and apoptosis in breast cancer cells induced by Origanum majorana extract: upregulation of TNF-? and downregulation of survivin and mutant p53. PLoS ONE. 2013;8:e56649 pubmed 出版商
Stingele S, Stoehr G, Peplowska K, Cox J, Mann M, Storchova Z. Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells. Mol Syst Biol. 2012;8:608 pubmed 出版商
Llopis A, Salvador N, Ercilla A, Guaita Esteruelas S, Barrantes I, Gupta J, et al. The stress-activated protein kinases p38?/? and JNK1/2 cooperate with Chk1 to inhibit mitotic entry upon DNA replication arrest. Cell Cycle. 2012;11:3627-37 pubmed 出版商
产品信息
目录代码 :
05-373
亚类别 :
Epigenetics & Nuclear Function
产品名称 :
抗细胞周期蛋白B1抗体, 克隆GNS3(8A5D12)
产品类型 :
抗体
克隆性 :
单克隆抗体
基因编号 :
P14635
宿主名称 :
小鼠
抗原 :
细胞周期蛋白B1
克隆 :
GNS3(8A5D12)
共轭标签 :
纯化
抗体亚型 :
mixed IgGs
产品描述 :
抗细胞周期蛋白B1抗体, 克隆GNS3(8A5D12)
交叉活性 :
人类;小鼠
背景 :
Regulation of cell cycle progression in eukaryotic cells depends on the expression of cyclin proteins. These proteins are the regulatory subunits of the cell cycle-dependent kinases that are responsible for the phosphorylation of several cellular targets. The B cyclins, when combined with p34cdc2, a catalytic subunit of the cell cycle dependent kinase, form an enzyme that is active at the transition to the G2 phase, attaining maximum level at M phase. At that phase, the complex associates with condensed chromosomes in prophase and metaphase and is degraded at the metaphase/anaphase transition. Anti-Cyclin B1 may be used for the detection of cyclin B1 expression and for measuring relative differences in cyclin B1 level as a function of cell cycle phase.
别名 :
G2/mitotic-specific cyclin B1;cyclin B1
免疫原 :
重组人类细胞周期蛋白B1
特异性 :
This antibody is specific for human cyclin B1, Mr 58 kDa. Does not cross-react with cyclin A or cyclin D.
包装尺寸 :
200微克
用途 :
免疫沉淀;免疫印迹
储存 :
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
公司信息
默克密理博中国
上海市浦东张江高科技园区晨晖路88号2号楼2楼
asiatechserv@millipore.com
http://www.millipore.com/china/wwcn/cnhome
400-889-1988
公司总部: 美国
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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