| 出版应用/物种/样本/稀释 | 参考文献 |
|---|
- 免疫组化-石蜡切片; 人类; 1:100; 图 1a
- 免疫印迹; 人类; 1:3000; 图 1c
| Jeong W, Park J, Kim W, Ro E, Jeon S, Lee S, et al. WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation. Nat Commun. 2019;10:295 pubmed 出版商 |
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- 免疫印迹; 人类; 图 4f
- 免疫印迹; 小鼠; 图 2b, 3e
| Ruess D, Heynen G, Ciecielski K, Ai J, Berninger A, Kabacaoglu D, et al. Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase. Nat Med. 2018;24:954-960 pubmed 出版商 |
- 免疫组化-石蜡切片; 人类; 图 s2
- 流式细胞仪; 人类; 表 1
- 免疫沉淀; 人类; 表 1
- 免疫细胞化学; 人类; 表 1
- 酶联免疫吸附测定; 人类; 表 1
- 免疫印迹; 人类; 图 1b
| Waters A, Ozkan Dagliyan I, Vaseva A, Fer N, Strathern L, Hobbs G, et al. Evaluation of the selectivity and sensitivity of isoform- and mutation-specific RAS antibodies. Sci Signal. 2017;10: pubmed 出版商 |
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- 免疫印迹; 人类; 1:2000; 图 4a, 5a
| Huang C, Huang S, Chien C, Lee H, Yang S, Chang C, et al. Impact of microsatellite status on chemotherapy for colorectal cancer patients with KRAS or BRAF mutation. Oncol Lett. 2016;12:4427-4434 pubmed 出版商 |
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- 免疫印迹; 小鼠; 图 1a
- 免疫印迹; 人类; 图 1a
- 免疫印迹; 仓鼠; 图 1d
| Battram A, Durrant T, Agbani E, Heesom K, Paul D, Piatt R, et al. The Phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P3) Binder Rasa3 Regulates Phosphoinositide 3-kinase (PI3K)-dependent Integrin αIIbβ3 Outside-in Signaling. J Biol Chem. 2017;292:1691-1704 pubmed 出版商 |
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- 免疫印迹; 小鼠; 1:2000; 图 4
- 免疫印迹; 人类; 1:2000; 图 1
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| Antic I, Biancucci M, Zhu Y, GIUS D, Satchell K. Site-specific processing of Ras and Rap1 Switch I by a MARTX toxin effector domain. Nat Commun. 2015;6:7396 pubmed 出版商 |
| Straniero V, Pallavicini M, Chiodini G, Ruggeri P, Fumagalli L, Bolchi C, et al. Farnesyltransferase inhibitors: CAAX mimetics based on different biaryl scaffolds. Bioorg Med Chem Lett. 2014;24:2924-7 pubmed 出版商 |
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| Gurung B, Muhammad A, Hua X. Menin is required for optimal processing of the microRNA let-7a. J Biol Chem. 2014;289:9902-8 pubmed 出版商 |
| Kloog Y, Mor A. Cytotoxic-T-lymphocyte antigen 4 receptor signaling for lymphocyte adhesion is mediated by C3G and Rap1. Mol Cell Biol. 2014;34:978-88 pubmed 出版商 |
| Kostenko S, Jensen K, Moens U. Phosphorylation of heat shock protein 40 (Hsp40/DnaJB1) by mitogen-activated protein kinase-activated protein kinase 5 (MK5/PRAK). Int J Biochem Cell Biol. 2014;47:29-37 pubmed 出版商 |
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| Haeussler D, Pimentel D, Hou X, Burgoyne J, Cohen R, Bachschmid M. Endomembrane H-Ras controls vascular endothelial growth factor-induced nitric-oxide synthase-mediated endothelial cell migration. J Biol Chem. 2013;288:15380-9 pubmed 出版商 |
| Vartanian S, BENTLEY C, Brauer M, Li L, Shirasawa S, Sasazuki T, et al. Identification of mutant K-Ras-dependent phenotypes using a panel of isogenic cell lines. J Biol Chem. 2013;288:2403-13 pubmed 出版商 |
| Redchuk T, Karasev M, Verkhusha P, Donnelly S, Hülsemann M, Virtanen J, et al. Optogenetic regulation of endogenous proteins. Nat Commun. 2020;11:605 pubmed 出版商 |
| Johnson C, Lin Y, Reid D, Parker J, Pavlopoulos S, Dischinger P, et al. Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D. Cell Rep. 2019;28:1538-1550.e7 pubmed 出版商 |
| Zhang P, He F, Bai J, Yamamoto S, Chen S, Zhang L, et al. Chromatin regulator Asxl1 loss and Nf1 haploinsufficiency cooperate to accelerate myeloid malignancy. J Clin Invest. 2018;128:5383-5398 pubmed 出版商 |
| Bydoun M, Sterea A, Liptay H, Uzans A, Huang W, Rodrigues G, et al. S100A10, a novel biomarker in pancreatic ductal adenocarcinoma. Mol Oncol. 2018;12:1895-1916 pubmed 出版商 |
| Jain P, Sethi S, Pratyusha V, Garai P, Naqvi N, Singh S, et al. Ras signaling activates glycosylphosphatidylinositol (GPI) anchor biosynthesis via the GPI-N-acetylglucosaminyltransferase (GPI-GnT) in Candida albicans. J Biol Chem. 2018;293:12222-12238 pubmed 出版商 |
| Wong G, Zhou J, Liu J, Wu Z, Xu X, Li T, et al. Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition. Nat Med. 2018;24:968-977 pubmed 出版商 |
| Thinon E, Fernandez J, Molina H, Hang H. Selective Enrichment and Direct Analysis of Protein S-Palmitoylation Sites. J Proteome Res. 2018;17:1907-1922 pubmed 出版商 |
| Datta A, Kim H, Lal M, McGee L, Johnson A, Moustafa A, et al. Manumycin A suppresses exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration-resistant prostate cancer cells. Cancer Lett. 2017;408:73-81 pubmed 出版商 |
| Martin T, Cook D, Choi M, Li M, Haigis K, Elledge S. A Role for Mitochondrial Translation in Promotion of Viability in K-Ras Mutant Cells. Cell Rep. 2017;20:427-438 pubmed 出版商 |
| Scavello M, Petlick A, Ramesh R, Thompson V, Lotfi P, Charest P. Protein kinase A regulates the Ras, Rap1 and TORC2 pathways in response to the chemoattractant cAMP in Dictyostelium. J Cell Sci. 2017;130:1545-1558 pubmed 出版商 |
| Gavin H, Beubier N, Satchell K. The Effector Domain Region of the Vibrio vulnificus MARTX Toxin Confers Biphasic Epithelial Barrier Disruption and Is Essential for Systemic Spread from the Intestine. PLoS Pathog. 2017;13:e1006119 pubmed 出版商 |
| Liu Y, Yang H, Cao J, Jiang Y, Hao J, Xu X, et al. KIAA1522 is a novel prognostic biomarker in patients with non-small cell lung cancer. Sci Rep. 2016;6:24786 pubmed 出版商 |
| Castellano E, Molina Arcas M, Krygowska A, East P, Warne P, Nicol A, et al. RAS signalling through PI3-Kinase controls cell migration via modulation of Reelin expression. Nat Commun. 2016;7:11245 pubmed 出版商 |
| Percher A, Ramakrishnan S, Thinon E, Yuan X, Yount J, Hang H. Mass-tag labeling reveals site-specific and endogenous levels of protein S-fatty acylation. Proc Natl Acad Sci U S A. 2016;113:4302-7 pubmed 出版商 |
| Roda D, Castillo J, Telechea Fernández M, Gil A, López Rodas G, Franco L, et al. EGF-Induced Acetylation of Heterogeneous Nuclear Ribonucleoproteins Is Dependent on KRAS Mutational Status in Colorectal Cancer Cells. PLoS ONE. 2015;10:e0130543 pubmed 出版商 |
| Choo K, Soon Y, Nguyen P, Hiew M, Huang C. MicroRNA-5p and -3p co-expression and cross-targeting in colon cancer cells. J Biomed Sci. 2014;21:95 pubmed 出版商 |
| Catanzaro J, Sheshadri N, Pan J, Sun Y, Shi C, Li J, et al. Oncogenic Ras induces inflammatory cytokine production by upregulating the squamous cell carcinoma antigens SerpinB3/B4. Nat Commun. 2014;5:3729 pubmed 出版商 |
| Tong J, Lung R, Sin F, Law P, Kang W, Chan A, et al. Characterization of rare transforming KRAS mutations in sporadic colorectal cancer. Cancer Biol Ther. 2014;15:768-76 pubmed 出版商 |
| Azrak S, Ginel Picardo A, Drosten M, Barbacid M, Santos E. Reversible, interrelated mRNA and miRNA expression patterns in the transcriptome of Rasless fibroblasts: functional and mechanistic implications. BMC Genomics. 2013;14:731 pubmed 出版商 |
| Jin Q, Ding W, Mulder K. The TGF? receptor-interacting protein km23-1/DYNLRB1 plays an adaptor role in TGF?1 autoinduction via its association with Ras. J Biol Chem. 2012;287:26453-63 pubmed 出版商 |
| Cook C, Kim A, Terao S, Gotoh A, Higuchi M. Consumption of oxygen: a mitochondrial-generated progression signal of advanced cancer. Cell Death Dis. 2012;3:e258 pubmed 出版商 |
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| Charette N, De Saeger C, Lannoy V, Horsmans Y, Leclercq I, Starkel P. Salirasib inhibits the growth of hepatocarcinoma cell lines in vitro and tumor growth in vivo through ras and mTOR inhibition. Mol Cancer. 2010;9:256 pubmed 出版商 |
| Holden P, Horton W. Crude subcellular fractionation of cultured mammalian cell lines. BMC Res Notes. 2009;2:243 pubmed 出版商 |
| Kawasaki K, Watabe T, Sase H, Hirashima M, Koide H, Morishita Y, et al. Ras signaling directs endothelial specification of VEGFR2+ vascular progenitor cells. J Cell Biol. 2008;181:131-41 pubmed 出版商 |
| Yokoyama T, Takano K, Yoshida A, Katada F, Sun P, Takenawa T, et al. DA-Raf1, a competent intrinsic dominant-negative antagonist of the Ras-ERK pathway, is required for myogenic differentiation. J Cell Biol. 2007;177:781-93 pubmed |
| Marti F, Garcia G, Lapinski P, Macgregor J, King P. Essential role of the T cell-specific adapter protein in the activation of LCK in peripheral T cells. J Exp Med. 2006;203:281-7 pubmed |
| Bivona T, Wiener H, Ahearn I, Silletti J, Chiu V, Philips M. Rap1 up-regulation and activation on plasma membrane regulates T cell adhesion. J Cell Biol. 2004;164:461-70 pubmed |
