产品简要
公司名称 :
默克密理博中国
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
产品类型 :
抗体
产品名称 :
Akt/PKB Antibody, PH Domain, clone SKB1
目录 :
05-591毫克
规格 :
1毫克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
SKB1
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫沉淀
更多信息或购买 :
文章摘录数: 2
出版应用/物种/样品/稀释参考文献
  • 免疫印迹; 人类; 1:500; 图 7a
Castella B, Kopecka J, Sciancalepore P, Mandili G, Foglietta M, Mitro N, et al. The ATP-binding cassette transporter A1 regulates phosphoantigen release and Vγ9Vδ2 T cell activation by dendritic cells. Nat Commun. 2017;8:15663 pubmed 出版商
Zhang W, Xiao H, Parkin K. Apoptosis in MCF-7 breast cancer cells induced by S-alkenylmercaptocysteine (CySSR) species derived from Allium tissues in combination with sodium selenite. Food Chem Toxicol. 2014;68:1-10 pubmed 出版商
产品信息
目录代码 :
05-591毫克
亚类别 :
Cell Signaling
产品名称 :
Anti-Akt/PKB Antibody, PH Domain, clone SKB1
产品类型 :
抗体
克隆性 :
单克隆抗体
基因编号 :
P31749
宿主名称 :
小鼠
抗原 :
Akt/PKB
克隆 :
克隆SKB1
共轭标签 :
纯化
抗体亚型 :
IgG
产品描述 :
Anti-Akt/PKB Antibody, PH Domain, clone SKB1
交叉活性 :
人类;小鼠;大鼠
背景 :
Akt (protein kinase B), a serine/threonine kinase, has emerged as a critical enzyme in signal transduction pathways involved in cell proliferation, apoptosis, angiogenesis, and diabetes. In mammals three isoforms of Akt (α, β, γ or Akt 1, 2, 3) are reported that exhibit a high degree of homology, but differ slightly in the localization of their regulatory phosphorylation sites. Akt α is the predominant isoform in most tissues, whereas the highest expression of Akt β is observed in the insulin-responsive tissues, and Akt γ is abundant in brain tissue. Each Akt isoform is composed of three functionally distinct regions: an N-terminal pleckstrin homology (PH) domain that provides a lipid-binding module to direct Akt to PIP2 and PIP3, a central catalytic domain, and a C-terminal hydrophobic motif.
免疫原 :
GST-fusion protein corresponding to residues 1-149 of human Akt
特异性 :
Recognizes Akt1/PKBα Akt2/PKBβ (30%) Akt3/PKBγ (weak to none) based on immunoblot analysis using 100 ng recombinant fusion protein for each isoform.
包装尺寸 :
1毫克
用途 :
免疫沉淀;免疫印迹
储存 :
Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
更多信息或购买 :
公司信息
默克密理博中国
上海市浦东张江高科技园区晨晖路88号2号楼2楼
asiatechserv@millipore.com
http://www.millipore.com/china/wwcn/cnhome
400-889-1988
公司总部: 美国
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

Hundreds of New Antibodies in the areas of:
  • • Cancer
  • • Nuclear Signaling
  • • Apoptosis
  • • Cardiovascular Disease
  • • Developmental Biology
  • • Metabolic Disease
  • • Neurodegenerative Disease
  • • Cell Biology
View all the new antibodies at www.emdmillipore.com.