| 出版应用/物种/样本/稀释 | 参考文献 |
|---|
| Colomer C, Margalef P, Villanueva A, Vert A, Pecharroman I, Sole L, et al. IKKα Kinase Regulates the DNA Damage Response and Drives Chemo-resistance in Cancer. Mol Cell. 2019;75:669-682.e5 pubmed 出版商 |
- 免疫细胞化学; 人类; 1:200; 图 e7a, e7c
| Chan E, Shibue T, McFarland J, Gaeta B, Ghandi M, Dumont N, et al. WRN helicase is a synthetic lethal target in microsatellite unstable cancers. Nature. 2019;568:551-556 pubmed 出版商 |
| Marmisolle I, MartÃnez J, Liu J, Mastrogiovanni M, Fergusson M, Rovira I, et al. Reciprocal regulation of acetyl-CoA carboxylase 1 and senescence in human fibroblasts involves oxidant mediated p38 MAPK activation. Arch Biochem Biophys. 2017;613:12-22 pubmed 出版商 |
| Benkafadar N, Menardo J, Bourien J, Nouvian R, François F, Decaudin D, et al. Reversible p53 inhibition prevents cisplatin ototoxicity without blocking chemotherapeutic efficacy. EMBO Mol Med. 2017;9:7-26 pubmed 出版商 |
| Cao N, Li J, Rao Y, Liu H, Wu J, Li B, et al. A potential role for protein palmitoylation and zDHHC16 in DNA damage response. BMC Mol Biol. 2016;17:12 pubmed 出版商 |
| Wang W, Long L, Wang L, Tan C, Fei X, Chen L, et al. Knockdown of Cathepsin L promotes radiosensitivity of glioma stem cells both in vivo and in vitro. Cancer Lett. 2016;371:274-84 pubmed 出版商 |
| Lee S, Bohrson C, Pike A, Wheelan S, Greider C. ATM Kinase Is Required for Telomere Elongation in Mouse and Human Cells. Cell Rep. 2015;13:1623-32 pubmed 出版商 |
- 免疫细胞化学; 大鼠; 1:200; 图 8
- 免疫沉淀; 小鼠; 图 8
- 免疫细胞化学; 小鼠; 1:200; 图 8
- 免疫印迹; 小鼠; 图 5
| Wang J, Chen S, Sun C, Chien T, Chern Y. A central role of TRAX in the ATM-mediated DNA repair. Oncogene. 2016;35:1657-70 pubmed 出版商 |
| Cheng H, Liang Y, Kuo Y, Chuu C, Lin C, Lee M, et al. Identification of thioridazine, an antipsychotic drug, as an antiglioblastoma and anticancer stem cell agent using public gene expression data. Cell Death Dis. 2015;6:e1753 pubmed 出版商 |
| Salzano M, Sanz GarcÃa M, Monsalve D, Moura D, Lazo P. VRK1 chromatin kinase phosphorylates H2AX and is required for foci formation induced by DNA damage. Epigenetics. 2015;10:373-83 pubmed 出版商 |
- 免疫组化-石蜡切片; 人类; 1:100; 图 6
- 免疫细胞化学; 人类; 1:100; 图 5
- 免疫印迹; 人类; 1:2000; 图 5
| Annovazzi L, Caldera V, Mellai M, Riganti C, Battaglia L, Chirio D, et al. The DNA damage/repair cascade in glioblastoma cell lines after chemotherapeutic agent treatment. Int J Oncol. 2015;46:2299-308 pubmed 出版商 |
| Luo Z, Feng X, Wang H, Xu W, Zhao Y, Ma W, et al. Mir-23a induces telomere dysfunction and cellular senescence by inhibiting TRF2 expression. Aging Cell. 2015;14:391-9 pubmed 出版商 |
| Nakahara T, Tanaka K, Ohno S, Egawa N, Yugawa T, Kiyono T. Activation of NF-κB by human papillomavirus 16 E1 limits E1-dependent viral replication through degradation of E1. J Virol. 2015;89:5040-59 pubmed 出版商 |
| Staquicini F, Qian M, Salameh A, Dobroff A, Edwards J, Cimino D, et al. Receptor tyrosine kinase EphA5 is a functional molecular target in human lung cancer. J Biol Chem. 2015;290:7345-59 pubmed 出版商 |
| Ferlazzo M, Sonzogni L, Granzotto A, Bodgi L, Lartin O, Devic C, et al. Mutations of the Huntington's disease protein impact on the ATM-dependent signaling and repair pathways of the radiation-induced DNA double-strand breaks: corrective effect of statins and bisphosphonates. Mol Neurobiol. 2014;49:1200-11 pubmed 出版商 |
| Chen Y, Kamili A, Hardy J, Groblewski G, Khanna K, Byrne J. Tumor protein D52 represents a negative regulator of ATM protein levels. Cell Cycle. 2013;12:3083-97 pubmed 出版商 |
| Hu R, Wang E, Peng G, Dai H, Lin S. Zinc finger protein 668 interacts with Tip60 to promote H2AX acetylation after DNA damage. Cell Cycle. 2013;12:2033-41 pubmed 出版商 |
| Licandro G, Ling Khor H, Beretta O, Lai J, Derks H, Laudisi F, et al. The NLRP3 inflammasome affects DNA damage responses after oxidative and genotoxic stress in dendritic cells. Eur J Immunol. 2013;43:2126-37 pubmed 出版商 |
| Lin R, Ho C, Liu L, Lyu Y. Topoisomerase II? deficiency enhances camptothecin-induced apoptosis. J Biol Chem. 2013;288:7182-92 pubmed 出版商 |
| Yan Q, Xu R, Zhu L, Cheng X, Wang Z, Manis J, et al. BAL1 and its partner E3 ligase, BBAP, link Poly(ADP-ribose) activation, ubiquitylation, and double-strand DNA repair independent of ATM, MDC1, and RNF8. Mol Cell Biol. 2013;33:845-57 pubmed 出版商 |
| Solarczyk K, Zarebski M, Dobrucki J. Inducing local DNA damage by visible light to study chromatin repair. DNA Repair (Amst). 2012;11:996-1002 pubmed 出版商 |
| Shechter D, Chitta R, Xiao A, Shabanowitz J, Hunt D, Allis C. A distinct H2A.X isoform is enriched in Xenopus laevis eggs and early embryos and is phosphorylated in the absence of a checkpoint. Proc Natl Acad Sci U S A. 2009;106:749-54 pubmed 出版商 |
| Mezzadra R, de Bruijn M, Jae L, Gomez Eerland R, Duursma A, Scheeren F, et al. SLFN11 can sensitize tumor cells towards IFN-γ-mediated T cell killing. PLoS ONE. 2019;14:e0212053 pubmed 出版商 |
| Chen M, Hsu W, Hsu S, Yang Y, Chuang T, Lin W, et al. PP4 deficiency leads to DNA replication stress that impairs immunoglobulin class switch efficiency. Cell Death Differ. 2019;26:1221-1234 pubmed 出版商 |
| Pustovalova M, Astrelina Т, Grekhova A, Vorobyeva N, Tsvetkova A, Blokhina T, et al. Residual γH2AX foci induced by low dose x-ray radiation in bone marrow mesenchymal stem cells do not cause accelerated senescence in the progeny of irradiated cells. Aging (Albany NY). 2017;9:2397-2410 pubmed 出版商 |
| Burke R, Marcus J, Orth J. Inhibition of exportin-1 function results in rapid cell cycle-associated DNA damage in cancer cells. Oncotarget. 2017;8:39460-39475 pubmed 出版商 |
| Pustovalova M, Grekhova A, Astrelina Т, Nikitina V, Dobrovolskaya E, Suchkova Y, et al. Accumulation of spontaneous ?H2AX foci in long-term cultured mesenchymal stromal cells. Aging (Albany NY). 2016;8:3498-3506 pubmed 出版商 |
| Parplys A, Zhao W, Sharma N, Groesser T, Liang F, Maranon D, et al. NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability. Nucleic Acids Res. 2015;43:9817-34 pubmed 出版商 |
| Oh W, Frost J. Rho GTPase independent regulation of ATM activation and cell survival by the RhoGEF Net1A. Cell Cycle. 2014;13:2765-72 pubmed 出版商 |
| Schmidt L, Wiedner M, Velimezi G, Prochazkova J, Owusu M, Bauer S, et al. ATMIN is required for the ATM-mediated signaling and recruitment of 53BP1 to DNA damage sites upon replication stress. DNA Repair (Amst). 2014;24:122-130 pubmed 出版商 |
| Soriani A, Iannitto M, Ricci B, Fionda C, Malgarini G, Morrone S, et al. Reactive oxygen species- and DNA damage response-dependent NK cell activating ligand upregulation occurs at transcriptional levels and requires the transcriptional factor E2F1. J Immunol. 2014;193:950-60 pubmed 出版商 |
| Singh R, Shankar B, Sainis K. TGF-?1-ROS-ATM-CREB signaling axis in macrophage mediated migration of human breast cancer MCF7 cells. Cell Signal. 2014;26:1604-15 pubmed 出版商 |
| Koyama T, Sun B, Tokunaga K, Tatsumi M, Ishizaka Y. DNA damage enhances integration of HIV-1 into macrophages by overcoming integrase inhibition. Retrovirology. 2013;10:21 pubmed 出版商 |
| Lundholm L, Haag P, Zong D, Juntti T, Mork B, Lewensohn R, et al. Resistance to DNA-damaging treatment in non-small cell lung cancer tumor-initiating cells involves reduced DNA-PK/ATM activation and diminished cell cycle arrest. Cell Death Dis. 2013;4:e478 pubmed 出版商 |
| Zhang T, Penicud K, Bruhn C, Loizou J, Kanu N, Wang Z, et al. Competition between NBS1 and ATMIN controls ATM signaling pathway choice. Cell Rep. 2012;2:1498-504 pubmed 出版商 |
| Jullien L, Mestre M, Roux P, Gire V. Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response. Nucleic Acids Res. 2013;41:900-11 pubmed 出版商 |
| Conradt L, Henrich A, Wirth M, Reichert M, Lesina M, Algül H, et al. Mdm2 inhibitors synergize with topoisomerase II inhibitors to induce p53-independent pancreatic cancer cell death. Int J Cancer. 2013;132:2248-57 pubmed 出版商 |
| Hasham M, Snow K, Donghia N, Branca J, Lessard M, Stavnezer J, et al. Activation-induced cytidine deaminase-initiated off-target DNA breaks are detected and resolved during S phase. J Immunol. 2012;189:2374-82 pubmed 出版商 |
| Duxin J, Moore H, Sidorova J, Karanja K, Honaker Y, Dao B, et al. Okazaki fragment processing-independent role for human Dna2 enzyme during DNA replication. J Biol Chem. 2012;287:21980-91 pubmed 出版商 |
| Ondovcik S, Tamblyn L, McPherson J, Wells P. Oxoguanine glycosylase 1 (OGG1) protects cells from DNA double-strand break damage following methylmercury (MeHg) exposure. Toxicol Sci. 2012;128:272-83 pubmed 出版商 |
| Pampeno C, Hurtado A, Meruelo D. ATM kinase is activated by sindbis viral vector infection. Virus Res. 2012;166:97-102 pubmed 出版商 |
| Shin Y, Choi Y, Erdin S, Yatsenko S, Kloc M, Yang F, et al. Hormad1 mutation disrupts synaptonemal complex formation, recombination, and chromosome segregation in mammalian meiosis. PLoS Genet. 2010;6:e1001190 pubmed 出版商 |
| Lee H, Trott J, Haque S, McCormick S, Chiorazzi N, Mongini P. A cyclooxygenase-2/prostaglandin E2 pathway augments activation-induced cytosine deaminase expression within replicating human B cells. J Immunol. 2010;185:5300-14 pubmed 出版商 |
| Kanu N, Penicud K, Hristova M, Wong B, Irvine E, Plattner F, et al. The ATM cofactor ATMIN protects against oxidative stress and accumulation of DNA damage in the aging brain. J Biol Chem. 2010;285:38534-42 pubmed 出版商 |
| See W, Miller J, Squatrito M, Holland E, Resh M, Koff A. Defective DNA double-strand break repair underlies enhanced tumorigenesis and chromosomal instability in p27-deficient mice with growth factor-induced oligodendrogliomas. Oncogene. 2010;29:1720-31 pubmed 出版商 |
| Rodier F, Coppe J, Patil C, Hoeijmakers W, Muñoz D, Raza S, et al. Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion. Nat Cell Biol. 2009;11:973-9 pubmed 出版商 |
| Sánchez Pérez Y, Chirino Y, Osornio Vargas Ã, Morales Bárcenas R, Gutiérrez RuÃz C, Vázquez López I, et al. DNA damage response of A549 cells treated with particulate matter (PM10) of urban air pollutants. Cancer Lett. 2009;278:192-200 pubmed 出版商 |
| Teoh N, Dan Y, Swisshelm K, Lehman S, Wright J, Haque J, et al. Defective DNA strand break repair causes chromosomal instability and accelerates liver carcinogenesis in mice. Hepatology. 2008;47:2078-88 pubmed 出版商 |
