Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

抗体

磷酸化组蛋白H3(Thr3)抗体, 克隆JY325, 兔单克隆

05-746R

100微升

单克隆

domestic rabbit

未共轭

JY325

Epigenetics & Nuclear Function

抗磷酸化组蛋白H3(Thr3)抗体, 克隆JY325, 兔单克隆

抗体

单克隆抗体

P68431

兔

磷酸化组蛋白H3(Thr3)

JY325

纯化

IgG

抗磷酸化组蛋白H3(Thr3)抗体, 克隆JY325, 兔单克隆

人类

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine. High levels of phosphorylation of Histone H3 are associated with mitosis. Consistent with this role, Histone H3 phosphorylated at threonine 3 has been shown to be recognized by the BIR domain Survivin, a member of the inhibitor of apoptosis (IAP) family.

组蛋白H3.1;组蛋白H3/a;组蛋白H3/b;组蛋白H3/c;组蛋白H3/d;组蛋白H3/f;组蛋白H3/h;组蛋白H3/I;组蛋白H3/j;组蛋白H3/k;组蛋白H3/l

KLH-conjugated linear peptide corresponding to human Histone H3 phosphorylated at Thr3.

This antibody recognizes Histone H3 phosphorylated at Thr3.

100微升

Western Blotting;Peptide Inhibition Assay

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.