This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
默克密理博中国
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
产品类型 :
抗体
产品名称 :
α-Tubulin Antibody, clone DM1A
目录 :
05-829
规格 :
200微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
DM1A

同一抗体克隆可从以下厂商购到:
反应物种 :
人类, 小鼠, 大鼠, , 斑马鱼, roundworm
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪
文章摘录数: 137
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 2d
Miles R, Kerridge C, Hilditch L, Monit C, Jacques D, Towers G. MxB sensitivity of HIV-1 is determined by a highly variable and dynamic capsid surface. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 小鼠; 图 3d, 3e
Satoh A, Han S, Araki M, Nakagawa Y, Ohno H, Mizunoe Y, et al. CREBH Improves Diet-Induced Obesity, Insulin Resistance, and Metabolic Disturbances by FGF21-Dependent and FGF21-Independent Mechanisms. iScience. 2020;23:100930 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 e5d
Eckert M, Coscia F, Chryplewicz A, Chang J, Hernandez K, Pan S, et al. Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts. Nature. 2019;: pubmed 出版商
  • 免疫印迹; 人类; 图 5d
Komori H, Goto Y, Kurayoshi K, Ozono E, Iwanaga R, Bradford A, et al. Differential requirement for dimerization partner DP between E2F-dependent activation of tumor suppressor and growth-related genes. Sci Rep. 2018;8:8438 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 5
Vogan J, Zhang X, Youmans D, Regalado S, Johnson J, Hockemeyer D, et al. Minimized human telomerase maintains telomeres and resolves endogenous roles of H/ACA proteins, TCAB1, and Cajal bodies. elife. 2016;5: pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 2
Meinhardt G, Saleh L, Otti G, Haider S, Velicky P, Fiala C, et al. Wingless ligand 5a is a critical regulator of placental growth and survival. Sci Rep. 2016;6:28127 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2d
Nakagawa Y, Oikawa F, Mizuno S, Ohno H, Yagishita Y, Satoh A, et al. Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system. Sci Rep. 2016;6:27857 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Lee J, Kuo C, Tsai S, Cheng S, Chen S, Chan H, et al. Inhibition of HDAC3- and HDAC6-Promoted Survivin Expression Plays an Important Role in SAHA-Induced Autophagy and Viability Reduction in Breast Cancer Cells. Front Pharmacol. 2016;7:81 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Vincent A, Berthel E, Dacheux E, Magnard C, Venezia N. BRCA1 affects protein phosphatase 6 signalling through its interaction with ANKRD28. Biochem J. 2016;473:949-60 pubmed 出版商
  • 免疫印迹; 人类; 图 s2
Bleckmann A, Conradi L, Menck K, Schmick N, Schubert A, Rietkötter E, et al. β-catenin-independent WNT signaling and Ki67 in contrast to the estrogen receptor status are prognostic and associated with poor prognosis in breast cancer liver metastases. Clin Exp Metastasis. 2016;33:309-23 pubmed 出版商
  • 免疫印迹; 斑马鱼; 1:1000; 图 s1
Jayachandran P, Olmo V, Sanchez S, McFarland R, Vital E, Werner J, et al. Microtubule-associated protein 1b is required for shaping the neural tube. Neural Dev. 2016;11:1 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 5
Soo Lee N, Jin Chung H, Kim H, Yun Lee S, Ji J, Seo Y, et al. TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage. Nat Commun. 2016;7:10463 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Kitamura A, Nakayama Y, Shibasaki A, Taki A, Yuno S, Takeda K, et al. Interaction of RNA with a C-terminal fragment of the amyotrophic lateral sclerosis-associated TDP43 reduces cytotoxicity. Sci Rep. 2016;6:19230 pubmed 出版商
  • 免疫印迹; roundworm ; 1:5000; 图 2
Zhang L, Ward J, Cheng Z, Dernburg A. The auxin-inducible degradation (AID) system enables versatile conditional protein depletion in C. elegans. Development. 2015;142:4374-84 pubmed 出版商
  • 免疫印迹; 人类; 图 8d
Lin K, Kao S, Lai C, Chen C, Wu C, Hsu H, et al. Tumor Suppressor Lzap Suppresses Wnt/β-Catenin Signaling to Promote Zebrafish Embryonic Ventral Cell Fates via the Suppression of Inhibitory Phosphorylation of Glycogen Synthase Kinase 3. J Biol Chem. 2015;290:29808-19 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4
Nakakido M, Deng Z, Suzuki T, Dohmae N, Nakamura Y, Hamamoto R. PRMT6 increases cytoplasmic localization of p21CDKN1A in cancer cells through arginine methylation and makes more resistant to cytotoxic agents. Oncotarget. 2015;6:30957-67 pubmed 出版商
  • 免疫印迹; 小鼠; 1:4000; 图 1
Wong P, Feng Y, Wang J, Shi R, Jiang X. Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A. Nat Commun. 2015;6:8048 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000
Hirunsai M, Srikuea R, Yimlamai T. Heat stress promotes extracellular matrix remodelling via TGF-β1 and MMP-2/TIMP-2 modulation in tenotomised soleus and plantaris muscles. Int J Hyperthermia. 2015;31:336-48 pubmed 出版商
  • 免疫印迹; 人类; 图 s3
Menck K, Scharf C, Bleckmann A, Dyck L, Rost U, Wenzel D, et al. Tumor-derived microvesicles mediate human breast cancer invasion through differentially glycosylated EMMPRIN. J Mol Cell Biol. 2015;7:143-53 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2e
Kong S, Thiruppathi M, Qiu Q, Lin Z, Dong H, Chini E, et al. DBC1 is a suppressor of B cell activation by negatively regulating alternative NF-κB transcriptional activity. J Immunol. 2014;193:5515-24 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Deng Z, Matsuda K, Tanikawa C, Lin J, Furukawa Y, Hamamoto R, et al. Late Cornified Envelope Group I, a novel target of p53, regulates PRMT5 activity. Neoplasia. 2014;16:656-64 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200
Strakova J, Dean J, Sharpe K, Meyers T, Odom G, Townsend D. Dystrobrevin increases dystrophin's binding to the dystrophin-glycoprotein complex and provides protection during cardiac stress. J Mol Cell Cardiol. 2014;76:106-15 pubmed 出版商
  • 免疫印迹; 小鼠
  • 免疫印迹; 人类
Yang B, Wagner J, Damaschke N, Yao T, Wuerzberger Davis S, Lee M, et al. A novel pathway links oxidative stress to loss of insulin growth factor-2 (IGF2) imprinting through NF-?B activation. PLoS ONE. 2014;9:e88052 pubmed 出版商
  • 免疫印迹; 人类
Almenar Queralt A, Kim S, Benner C, Herrera C, Kang D, Garcia Bassets I, et al. Presenilins regulate neurotrypsin gene expression and neurotrypsin-dependent agrin cleavage via cyclic AMP response element-binding protein (CREB) modulation. J Biol Chem. 2013;288:35222-36 pubmed 出版商
  • 免疫印迹; 人类; 图 7
Barbeau D, La K, Kim D, Kerpedjieva S, Shurin G, Tamama K. Early growth response-2 signaling mediates immunomodulatory effects of human multipotential stromal cells. Stem Cells Dev. 2014;23:155-66 pubmed 出版商
  • 免疫印迹; 小鼠
Ma T, Galimberti F, Erkmen C, Memoli V, Chinyengetere F, SEMPERE L, et al. Comparing histone deacetylase inhibitor responses in genetically engineered mouse lung cancer models and a window of opportunity trial in patients with lung cancer. Mol Cancer Ther. 2013;12:1545-55 pubmed 出版商
  • 免疫印迹; 人类
Ferro M, Giuberti G, Zappavigna S, Perdonà S, Facchini G, Sperlongano P, et al. Chondroitin sulphate enhances the antitumor activity of gemcitabine and mitomycin-C in bladder cancer cells with different mechanisms. Oncol Rep. 2012;27:409-15 pubmed 出版商
  • 免疫印迹; 人类
Hsu F, Yang M, Lin E, Tseng C, Lin H. The significance of Her2 on androgen receptor protein stability in the transition of androgen requirement in prostate cancer cells. Am J Physiol Endocrinol Metab. 2011;300:E902-8 pubmed 出版商
Yu B, Ma J, Li J, Wang D, Wang Z, Wang S. Mitochondrial phosphatase PGAM5 modulates cellular senescence by regulating mitochondrial dynamics. Nat Commun. 2020;11:2549 pubmed 出版商
Lu Y, Stuart J, Talbot Cooper C, Agrawal Singh S, Huntly B, Smid A, et al. Histone deacetylase 4 promotes type I interferon signaling, restricts DNA viruses, and is degraded via vaccinia virus protein C6. Proc Natl Acad Sci U S A. 2019;116:11997-12006 pubmed 出版商
Pallett M, Ren H, Zhang R, Scutts S, Gonzalez L, Zhu Z, et al. Vaccinia Virus BBK E3 Ligase Adaptor A55 Targets Importin-Dependent NF-κB Activation and Inhibits CD8+ T-Cell Memory. J Virol. 2019;93: pubmed 出版商
Sulli G, Rommel A, Wang X, Kolar M, Puca F, Saghatelian A, et al. Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence. Nature. 2018;553:351-355 pubmed 出版商
Lee Y, Lim J, Jeoun U, Min S, Lee E, Kwon S, et al. Lactate-mediated mitoribosomal defects impair mitochondrial oxidative phosphorylation and promote hepatoma cell invasiveness. J Biol Chem. 2017;292:20208-20217 pubmed 出版商
Chen Y, Chen Y, Chang Y, Wu C, Ko Y, Tsao S, et al. Epstein-Barr Virus Rta-Mediated Accumulation of DNA Methylation Interferes with CTCF Binding in both Host and Viral Genomes. J Virol. 2017;91: pubmed 出版商
Na T, Kim G, Oh H, Lee M, Han Y, Kim K, et al. The trisaccharide raffinose modulates epidermal differentiation through activation of liver X receptor. Sci Rep. 2017;7:43823 pubmed 出版商
Huang G, Ge G, Izzi V, Greenspan D. α3 Chains of type V collagen regulate breast tumour growth via glypican-1. Nat Commun. 2017;8:14351 pubmed 出版商
Hentati Kallel M, Le Jan S, Bernard P, Antonicelli F, Trussardi Regnier A. Histone deacetylases meet microRNA-associated MMP-9 expression regulation in glucocorticoid-sensitive and -resistant cell lines. Int J Oncol. 2017;50:717-726 pubmed 出版商
Wan L, Maisonneuve P, Szilard R, Lambert J, Ng T, Manczyk N, et al. Proteomic analysis of the human KEOPS complex identifies C14ORF142 as a core subunit homologous to yeast Gon7. Nucleic Acids Res. 2017;45:805-817 pubmed 出版商
Kim G, Lee S, Cho H, Kim M, Shin E, Oh J. Hepatitis C Virus Core Protein Promotes miR-122 Destabilization by Inhibiting GLD-2. PLoS Pathog. 2016;12:e1005714 pubmed 出版商
Weaver E, Zamora F, Puplampu Dove Y, Kiessu E, Hearne J, Martin Caraballo M. Regulation of T-type calcium channel expression by sodium butyrate in prostate cancer cells. Eur J Pharmacol. 2015;749:20-31 pubmed 出版商
Rwigemera A, Mamelona J, Martin L. Comparative effects between fucoxanthinol and its precursor fucoxanthin on viability and apoptosis of breast cancer cell lines MCF-7 and MDA-MB-231. Anticancer Res. 2015;35:207-19 pubmed
Huynh F, Jones F. MicroRNA-7 inhibits multiple oncogenic pathways to suppress HER2Δ16 mediated breast tumorigenesis and reverse trastuzumab resistance. PLoS ONE. 2014;9:e114419 pubmed 出版商
Stroebel D, Carvalho S, Grand T, Zhu S, Paoletti P. Controlling NMDA receptor subunit composition using ectopic retention signals. J Neurosci. 2014;34:16630-6 pubmed 出版商
Kacsinta A, Rubenstein C, Sroka I, Pawar S, Gard J, Nagle R, et al. Intracellular modifiers of integrin alpha 6p production in aggressive prostate and breast cancer cell lines. Biochem Biophys Res Commun. 2014;454:335-40 pubmed 出版商
Mardilovich K, Gabrielsen M, McGarry L, Orange C, Patel R, Shanks E, et al. Elevated LIM kinase 1 in nonmetastatic prostate cancer reflects its role in facilitating androgen receptor nuclear translocation. Mol Cancer Ther. 2015;14:246-58 pubmed 出版商
Jansen S, Holman R, Hedemann I, Frankes E, Elzinga C, Timens W, et al. Prostaglandin E2 promotes MYCN non-amplified neuroblastoma cell survival via β-catenin stabilization. J Cell Mol Med. 2015;19:210-26 pubmed 出版商
Chan M, Gravel M, Bramoullé A, Bridon G, Avizonis D, Shore G, et al. Synergy between the NAMPT inhibitor GMX1777(8) and pemetrexed in non-small cell lung cancer cells is mediated by PARP activation and enhanced NAD consumption. Cancer Res. 2014;74:5948-54 pubmed 出版商
Ishii H, Saitoh M, Sakamoto K, Kondo T, Katoh R, Tanaka S, et al. Epithelial splicing regulatory proteins 1 (ESRP1) and 2 (ESRP2) suppress cancer cell motility via different mechanisms. J Biol Chem. 2014;289:27386-99 pubmed 出版商
Díaz N, Morera L, Verra D, Contin M, Guido M. Early appearance of nonvisual and circadian markers in the developing inner retinal cells of chicken. Biomed Res Int. 2014;2014:646847 pubmed 出版商
Lin L, Yang S, Chu J, Wang L, Ning L, Zhang T, et al. Region-specific expression of tau, amyloid-? protein precursor, and synaptic proteins at physiological condition or under endoplasmic reticulum stress in rats. J Alzheimers Dis. 2014;41:1149-63 pubmed 出版商
Rwigemera A, Mamelona J, Martin L. Inhibitory effects of fucoxanthinol on the viability of human breast cancer cell lines MCF-7 and MDA-MB-231 are correlated with modulation of the NF-kappaB pathway. Cell Biol Toxicol. 2014;30:157-67 pubmed 出版商
Sullivan S, Dillon G, Sullivan J, Ho A. Mint proteins are required for synaptic activity-dependent amyloid precursor protein (APP) trafficking and amyloid ? generation. J Biol Chem. 2014;289:15374-83 pubmed 出版商
Khiati S, Dalla Rosa I, Sourbier C, Ma X, Rao V, Neckers L, et al. Mitochondrial topoisomerase I (top1mt) is a novel limiting factor of doxorubicin cardiotoxicity. Clin Cancer Res. 2014;20:4873-81 pubmed 出版商
Lysko D, Putt M, Golden J. SDF1 reduces interneuron leading process branching through dual regulation of actin and microtubules. J Neurosci. 2014;34:4941-62 pubmed 出版商
Almenar Queralt A, Falzone T, Shen Z, Lillo C, Killian R, Arreola A, et al. UV irradiation accelerates amyloid precursor protein (APP) processing and disrupts APP axonal transport. J Neurosci. 2014;34:3320-39 pubmed 出版商
Maida Y, Yasukawa M, Okamoto N, Ohka S, Kinoshita K, Totoki Y, et al. Involvement of telomerase reverse transcriptase in heterochromatin maintenance. Mol Cell Biol. 2014;34:1576-93 pubmed 出版商
Sokolowski J, Gamage K, Heffron D, LeBlanc A, Deppmann C, Mandell J. Caspase-mediated cleavage of actin and tubulin is a common feature and sensitive marker of axonal degeneration in neural development and injury. Acta Neuropathol Commun. 2014;2:16 pubmed 出版商
Ting C, Huang H, Huang T, Wu C, Chen J. The mechanisms by which pardaxin, a natural cationic antimicrobial peptide, targets the endoplasmic reticulum and induces c-FOS. Biomaterials. 2014;35:3627-40 pubmed 出版商
Wong Y, Holzbaur E. The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation. J Neurosci. 2014;34:1293-305 pubmed 出版商
Bazzini C, Rossetti V, Civello D, Sassone F, Vezzoli V, Persani L, et al. Short- and long- term effects of cigarette smoke exposure on glutathione homeostasis in human bronchial epithelial cells. Cell Physiol Biochem. 2013;32:129-45 pubmed 出版商
Jiang Q, Wang L, Guan Y, Xu H, Niu Y, Han L, et al. Golgin-84-associated Golgi fragmentation triggers tau hyperphosphorylation by activation of cyclin-dependent kinase-5 and extracellular signal-regulated kinase. Neurobiol Aging. 2014;35:1352-63 pubmed 出版商
Chang K, Chang W, Chang Y, Hung L, Lai C, Yeh Y, et al. Ran GTPase-activating protein 1 is a therapeutic target in diffuse large B-cell lymphoma. PLoS ONE. 2013;8:e79863 pubmed 出版商
Rossi G, Conconi D, Panzeri E, Paoletta L, Piccoli E, Ferretti M, et al. Mutations in MAPT give rise to aneuploidy in animal models of tauopathy. Neurogenetics. 2014;15:31-40 pubmed 出版商
Grivas P, Day K, Karatsinides A, Paul A, Shakir N, Owainati I, et al. Evaluation of the antitumor activity of dacomitinib in models of human bladder cancer. Mol Med. 2013;19:367-76 pubmed 出版商
Hoshi T, Tezuka T, Yokoyama K, Iemura S, Natsume T, Yamanashi Y. Mesdc2 plays a key role in cell-surface expression of Lrp4 and postsynaptic specialization in myotubes. FEBS Lett. 2013;587:3749-54 pubmed 出版商
Wang X, Wang L, Tang H, Shan W, Wang X, Liu D, et al. Acetyl-L-carnitine rescues scopolamine-induced memory deficits by restoring insulin-like growth factor II via decreasing p53 oxidation. Neuropharmacology. 2014;76 Pt A:80-7 pubmed 出版商
Barrio L, Sáez de Guinoa J, Carrasco Y. TLR4 signaling shapes B cell dynamics via MyD88-dependent pathways and Rac GTPases. J Immunol. 2013;191:3867-75 pubmed 出版商
Beharry C, Alaniz M, Alonso A. Expression of Alzheimer-like pathological human tau induces a behavioral motor and olfactory learning deficit in Drosophila melanogaster. J Alzheimers Dis. 2013;37:539-50 pubmed 出版商
Funahashi Y, Namba T, Fujisue S, Itoh N, Nakamuta S, Kato K, et al. ERK2-mediated phosphorylation of Par3 regulates neuronal polarization. J Neurosci. 2013;33:13270-85 pubmed 出版商
Kozono S, Ohuchida K, Ohtsuka T, Cui L, Eguchi D, Fujiwara K, et al. S100A4 mRNA expression level is a predictor of radioresistance of pancreatic cancer cells. Oncol Rep. 2013;30:1601-8 pubmed 出版商
Silberberg Y, Kawamura R, Ryu S, Fukazawa K, Ishihara K, Nakamura C. Detection of microtubules in vivo using antibody-immobilized nanoneedles. J Biosci Bioeng. 2014;117:107-12 pubmed 出版商
Buttler K, Becker J, Pukrop T, Wilting J. Maldevelopment of dermal lymphatics in Wnt5a-knockout-mice. Dev Biol. 2013;381:365-76 pubmed 出版商
Geißler V, Altmeyer S, Stein B, Uhlmann Schiffler H, Stahl H. The RNA helicase Ddx5/p68 binds to hUpf3 and enhances NMD of Ddx17/p72 and Smg5 mRNA. Nucleic Acids Res. 2013;41:7875-88 pubmed 出版商
Vilagran I, Castillo J, Bonet S, Sancho S, Yeste M, Estanyol J, et al. Acrosin-binding protein (ACRBP) and triosephosphate isomerase (TPI) are good markers to predict boar sperm freezing capacity. Theriogenology. 2013;80:443-50 pubmed 出版商
Fradet Turcotte A, Canny M, Escribano Diaz C, Orthwein A, Leung C, Huang H, et al. 53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark. Nature. 2013;499:50-4 pubmed 出版商
Huang Z, Murphy S. Increased Intragenic IGF2 Methylation is Associated with Repression of Insulator Activity and Elevated Expression in Serous Ovarian Carcinoma. Front Oncol. 2013;3:131 pubmed 出版商
Motizuki M, Isogaya K, Miyake K, Ikushima H, Kubota T, Miyazono K, et al. Oligodendrocyte transcription factor 1 (Olig1) is a Smad cofactor involved in cell motility induced by transforming growth factor-?. J Biol Chem. 2013;288:18911-22 pubmed 出版商
Brochier C, Dennis G, Rivieccio M, McLaughlin K, Coppola G, Ratan R, et al. Specific acetylation of p53 by HDAC inhibition prevents DNA damage-induced apoptosis in neurons. J Neurosci. 2013;33:8621-32 pubmed 出版商
Gillis J, Selth L, Centenera M, Townley S, Sun S, Plymate S, et al. Constitutively-active androgen receptor variants function independently of the HSP90 chaperone but do not confer resistance to HSP90 inhibitors. Oncotarget. 2013;4:691-704 pubmed
Park S, Riley P, Frisch S. Regulation of anoikis by deleted in breast cancer-1 (DBC1) through NF-κB. Apoptosis. 2013;18:949-62 pubmed 出版商
Maor Nof M, Homma N, Raanan C, Nof A, Hirokawa N, Yaron A. Axonal pruning is actively regulated by the microtubule-destabilizing protein kinesin superfamily protein 2A. Cell Rep. 2013;3:971-7 pubmed 出版商
Márquez Navarro A, Pérez Reyes A, Zepeda Rodriguez A, Reynoso Ducoing O, Hernández Campos A, Hernández Luis F, et al. RCB20, an experimental benzimidazole derivative, affects tubulin expression and induces gross anatomical changes in Taenia crassiceps cysticerci. Parasitol Res. 2013;112:2215-26 pubmed 出版商
Kuszczyk M, Sanchez S, Pankiewicz J, Kim J, Duszczyk M, Guridi M, et al. Blocking the interaction between apolipoprotein E and A? reduces intraneuronal accumulation of A? and inhibits synaptic degeneration. Am J Pathol. 2013;182:1750-68 pubmed 出版商
Tang J, Michaelis K, Nozik Grayck E, Seedorf G, Hartman Filson M, Abman S, et al. The NF-?B inhibitory proteins I?B? and I?B? mediate disparate responses to inflammation in fetal pulmonary endothelial cells. J Immunol. 2013;190:2913-23 pubmed 出版商
Sun C, Nirmalananda S, Jenkins C, Debnath S, Balambika R, Fata J, et al. First ayurvedic approach towards green drugs: anti cervical cancer-cell properties of Clerodendrum viscosum root extract. Anticancer Agents Med Chem. 2013;13:1469-76 pubmed
Kozono S, Ohuchida K, Eguchi D, Ikenaga N, Fujiwara K, Cui L, et al. Pirfenidone inhibits pancreatic cancer desmoplasia by regulating stellate cells. Cancer Res. 2013;73:2345-56 pubmed 出版商
Bubenshchikova E, Ichimura K, Fukuyo Y, Powell R, Hsu C, Morrical S, et al. Wtip and Vangl2 are required for mitotic spindle orientation and cloaca morphogenesis. Biol Open. 2012;1:588-96 pubmed 出版商
Dalvai M, Bellucci L, Fleury L, Lavigne A, Moutahir F, Bystricky K. H2A.Z-dependent crosstalk between enhancer and promoter regulates cyclin D1 expression. Oncogene. 2013;32:4243-51 pubmed 出版商
Buchsbaum S, Bercovich B, Ziv T, Ciechanover A. Modification of the inflammatory mediator LRRFIP2 by the ubiquitin-like protein FAT10 inhibits its activity during cellular response to LPS. Biochem Biophys Res Commun. 2012;428:11-6 pubmed 出版商
Manni M, De Siena G, Saba A, Marchini M, Landucci E, Gerace E, et al. Pharmacological effects of 3-iodothyronamine (T1AM) in mice include facilitation of memory acquisition and retention and reduction of pain threshold. Br J Pharmacol. 2013;168:354-62 pubmed 出版商
Eguchi D, Ikenaga N, Ohuchida K, Kozono S, Cui L, Fujiwara K, et al. Hypoxia enhances the interaction between pancreatic stellate cells and cancer cells via increased secretion of connective tissue growth factor. J Surg Res. 2013;181:225-33 pubmed 出版商
Chaufty J, Sullivan S, Ho A. Intracellular amyloid precursor protein sorting and amyloid-? secretion are regulated by Src-mediated phosphorylation of Mint2. J Neurosci. 2012;32:9613-25 pubmed 出版商
Alves Silva J, Sánchez Soriano N, Beaven R, Klein M, Parkin J, Millard T, et al. Spectraplakins promote microtubule-mediated axonal growth by functioning as structural microtubule-associated proteins and EB1-dependent +TIPs (tip interacting proteins). J Neurosci. 2012;32:9143-58 pubmed 出版商
Ji K, Tsirka S. Inflammation modulates expression of laminin in the central nervous system following ischemic injury. J Neuroinflammation. 2012;9:159 pubmed 出版商
Balzer E, Tong Z, Paul C, Hung W, Stroka K, Boggs A, et al. Physical confinement alters tumor cell adhesion and migration phenotypes. FASEB J. 2012;26:4045-56 pubmed 出版商
Fujimura A, Kishimoto H, Yanagisawa J, Kimura K. Enhancer of rudimentary homolog (ERH) plays an essential role in the progression of mitosis by promoting mitotic chromosome alignment. Biochem Biophys Res Commun. 2012;423:588-92 pubmed 出版商
Wood J, Wang J, Benovic J, Ferkey D. Structural domains required for Caenorhabditis elegans G protein-coupled receptor kinase 2 (GRK-2) function in vivo. J Biol Chem. 2012;287:12634-44 pubmed 出版商
Chow W, Luk H, Chan H, Lau K. Degradation of mutant huntingtin via the ubiquitin/proteasome system is modulated by FE65. Biochem J. 2012;443:681-9 pubmed 出版商
Nummela P, Lammi J, Soikkeli J, Saksela O, Laakkonen P, Hölttä E. Transforming growth factor beta-induced (TGFBI) is an anti-adhesive protein regulating the invasive growth of melanoma cells. Am J Pathol. 2012;180:1663-74 pubmed 出版商
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产品信息
目录代码 :
05-829
亚类别 :
Cell Structure
产品名称 :
Anti-α-Tubulin Antibody, clone DM1A
产品类型 :
抗体
克隆性 :
单克隆抗体
基因编号 :
Q71U36
宿主名称 :
小鼠
抗原 :
α-Tubulin
克隆 :
DM1A
共轭标签 :
纯化
抗体亚型 :
IgG1
产品描述 :
Anti-α-Tubulin Antibody, clone DM1A
交叉活性 :
Rat;Mouse;Pig;Bovine;Avian;Guinea Pig;Human
背景 :
Microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Tubulin itself is a globular protein which consists of two polypeptides (alpha and beta tubulin). Alpha and beta tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22 nm diameter. Tyrosine ligase ads a C-terminal tyrosin to monomeric alpha tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton associated carboxypeptidase. Detyrosinated alpha tubulin is referred to as Glu-tubulin. Another post-translational modification of detyrosinated alpha tubulin is C-terminal polyglutamylation which is characteristic for microtubules in neuronal cells and the mitotic spindle.
别名 :
Alpha-tubulin 3;Tubulin B-alpha-1;Tubulin alpha-3 chain;tubulin, alpha 1a;tubulin, alpha 3;tubulin, alpha, brain-specific
免疫原 :
Purified human brain α-Tubulin. The epitope recognized by this antibody has been mapped to amino acids 426-450 (AALEKDYEEVGVDSVEGEGEEEGEE).
特异性 :
Recognizes α-Tubulin, clone DM1A, MW 50-60 kDa. The epitope recognized by this antibody has been mapped to amino acids 426-450.
包装尺寸 :
200微克
用途 :
免疫细胞化学;免疫荧光;免疫印迹
储存 :
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variabillity in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
公司信息
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asiatechserv@millipore.com
http://www.millipore.com/china/wwcn/cnhome
400-889-1988
公司总部: 美国
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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