This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
默克密理博中国
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
产品类型 :
抗体
产品名称 :
Histone H4 Antibody, pan, clone 62-141-13, rabbit monoclonal
目录 :
05-858
规格 :
100微升
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
62-141-13
反应物种 :
fission yeast, 人类, 小鼠, , brewer's yeast, fruit fly , roundworm
应用 :
免疫印迹, 染色质免疫沉淀 , ChIP-Seq
文章摘录数: 53
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 5a
Demetriadou C, Pavlou D, Mpekris F, Achilleos C, Stylianopoulos T, Zaravinos A, et al. NAA40 contributes to colorectal cancer growth by controlling PRMT5 expression. Cell Death Dis. 2019;10:236 pubmed 出版商
  • 免疫印迹; 人类; 图 s4c
Warkocki Z, Krawczyk P, Adamska D, Bijata K, Garcia Perez J, Dziembowski A. Uridylation by TUT4/7 Restricts Retrotransposition of Human LINE-1s. Cell. 2018;174:1537-1548.e29 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1b
Gocheva V, Naba A, Bhutkar A, Guardia T, Miller K, Li C, et al. Quantitative proteomics identify Tenascin-C as a promoter of lung cancer progression and contributor to a signature prognostic of patient survival. Proc Natl Acad Sci U S A. 2017;114:E5625-E5634 pubmed 出版商
  • ChIP-Seq; 小鼠; 图 s3h
Mews P, Donahue G, Drake A, Luczak V, Abel T, Berger S. Acetyl-CoA synthetase regulates histone acetylation and hippocampal memory. Nature. 2017;546:381-386 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠; 图 8
  • 免疫印迹; 小鼠; 图 8a
Liu Y, Wang T, Zhang R, Fu W, Wang X, Wang F, et al. Calorie restriction protects against experimental abdominal aortic aneurysms in mice. J Exp Med. 2016;213:2473-2488 pubmed
  • 免疫印迹; 人类; 1:3000; 图 s14
Guturi K, Bohgaki M, Bohgaki T, Srikumar T, Ng D, Kumareswaran R, et al. RNF168 and USP10 regulate topoisomerase IIα function via opposing effects on its ubiquitylation. Nat Commun. 2016;7:12638 pubmed 出版商
  • 免疫印迹; 小鼠; 图 8b
You L, Li L, Zou J, Yan K, Belle J, Nijnik A, et al. BRPF1 is essential for development of fetal hematopoietic stem cells. J Clin Invest. 2016;126:3247-62 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Hasvold G, Lund Andersen C, Lando M, Patzke S, Hauge S, Suo Z, et al. Hypoxia-induced alterations of G2 checkpoint regulators. Mol Oncol. 2016;10:764-73 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Seidel C, Schnekenburger M, Mazumder A, Teiten M, Kirsch G, Dicato M, et al. 4-Hydroxybenzoic acid derivatives as HDAC6-specific inhibitors modulating microtubular structure and HSP90α chaperone activity against prostate cancer. Biochem Pharmacol. 2016;99:31-52 pubmed 出版商
  • 免疫印迹; brewer's yeast; 图 5
Pamblanco M, Oliete Calvo P, García Oliver E, Luz Valero M, Sánchez Del Pino M, Rodriguez Navarro S. Unveiling novel interactions of histone chaperone Asf1 linked to TREX-2 factors Sus1 and Thp1. Nucleus. 2014;5:247-59 pubmed 出版商
  • 免疫印迹; fission yeast
Creamer K, Job G, Shanker S, Neale G, Lin Y, Bartholomew B, et al. The Mi-2 homolog Mit1 actively positions nucleosomes within heterochromatin to suppress transcription. Mol Cell Biol. 2014;34:2046-61 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1f
Alabert C, Bukowski Wills J, Lee S, Kustatscher G, Nakamura K, de Lima Alves F, et al. Nascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components. Nat Cell Biol. 2014;16:281-93 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Kapoor Vazirani P, Vertino P. A dual role for the histone methyltransferase PR-SET7/SETD8 and histone H4 lysine 20 monomethylation in the local regulation of RNA polymerase II pausing. J Biol Chem. 2014;289:7425-37 pubmed 出版商
  • 免疫印迹; 人类
Lau P, Cheung P. Elucidating combinatorial histone modifications and crosstalks by coupling histone-modifying enzyme with biotin ligase activity. Nucleic Acids Res. 2013;41:e49 pubmed 出版商
  • 染色质免疫沉淀 ; 鸡
Hassan Zadeh V, Chilaka S, Cadoret J, Ma M, Boggetto N, West A, et al. USF binding sequences from the HS4 insulator element impose early replication timing on a vertebrate replicator. PLoS Biol. 2012;10:e1001277 pubmed 出版商
  • 免疫印迹; 人类
Larsson P, Ulfhammer E, Magnusson M, Bergh N, Lunke S, El Osta A, et al. Role of histone acetylation in the stimulatory effect of valproic acid on vascular endothelial tissue-type plasminogen activator expression. PLoS ONE. 2012;7:e31573 pubmed 出版商
  • 免疫印迹; 人类
Karius T, Schnekenburger M, Ghelfi J, Walter J, Dicato M, Diederich M. Reversible epigenetic fingerprint-mediated glutathione-S-transferase P1 gene silencing in human leukemia cell lines. Biochem Pharmacol. 2011;81:1329-42 pubmed 出版商
  • 免疫印迹; fruit fly ; 1:1000
  • 染色质免疫沉淀 ; roundworm
Egelhofer T, Minoda A, Klugman S, Lee K, Kolasinska Zwierz P, Alekseyenko A, et al. An assessment of histone-modification antibody quality. Nat Struct Mol Biol. 2011;18:91-3 pubmed 出版商
Rutowicz K, Lirski M, Mermaz B, Teano G, Schubert J, Mestiri I, et al. Linker histones are fine-scale chromatin architects modulating developmental decisions in Arabidopsis. Genome Biol. 2019;20:157 pubmed 出版商
Lambert J, Picaud S, Fujisawa T, Hou H, Savitsky P, Uusküla Reimand L, et al. Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains. Mol Cell. 2019;73:621-638.e17 pubmed 出版商
Mitra M, Johnson E, Swamy V, Nersesian L, Corney D, Robinson D, et al. Alternative polyadenylation factors link cell cycle to migration. Genome Biol. 2018;19:176 pubmed 出版商
Slaughter M, Shanle E, McFadden A, Hollis E, Suttle L, Strahl B, et al. PBRM1 bromodomains variably influence nucleosome interactions and cellular function. J Biol Chem. 2018;293:13592-13603 pubmed 出版商
Mo X, Zhang H, Preston S, Martin K, Zhou B, Vadalia N, et al. Interferon-γ Signaling in Melanocytes and Melanoma Cells Regulates Expression of CTLA-4. Cancer Res. 2018;78:436-450 pubmed 出版商
Boudoures A, Pfeil J, Steenkiste E, Hoffman R, Bailey E, Wilkes S, et al. A Novel Histone Crosstalk Pathway Important for Regulation of UV-Induced DNA Damage Repair in Saccharomyces cerevisiae. Genetics. 2017;206:1389-1402 pubmed 出版商
Carrer A, Parris J, Trefely S, Henry R, Montgomery D, Torres A, et al. Impact of a High-fat Diet on Tissue Acyl-CoA and Histone Acetylation Levels. J Biol Chem. 2017;292:3312-3322 pubmed 出版商
Min C, Moore N, Shearstone J, Quayle S, Huang P, Van Duzer J, et al. Selective Inhibitors of Histone Deacetylases 1 and 2 Synergize with Azacitidine in Acute Myeloid Leukemia. PLoS ONE. 2017;12:e0169128 pubmed 出版商
Trécul A, Morceau F, Gaigneaux A, Schnekenburger M, Dicato M, Diederich M. Valproic acid regulates erythro-megakaryocytic differentiation through the modulation of transcription factors and microRNA regulatory micro-networks. Biochem Pharmacol. 2014;92:299-311 pubmed 出版商
Bunnik E, Polishko A, Prudhomme J, Ponts N, Gill S, Lonardi S, et al. DNA-encoded nucleosome occupancy is associated with transcription levels in the human malaria parasite Plasmodium falciparum. BMC Genomics. 2014;15:347 pubmed 出版商
Khair L, Guikema J, Linehan E, Ucher A, Leus N, Ogilvie C, et al. ATM increases activation-induced cytidine deaminase activity at downstream S regions during class-switch recombination. J Immunol. 2014;192:4887-96 pubmed 出版商
Biniossek M, Lechel A, Rudolph K, Martens U, Zimmermann S. Quantitative proteomic profiling of tumor cell response to telomere dysfunction using isotope-coded protein labeling (ICPL) reveals interaction network of candidate senescence markers. J Proteomics. 2013;91:515-35 pubmed 出版商
Neguembor M, Xynos A, Onorati M, Caccia R, Bortolanza S, Godio C, et al. FSHD muscular dystrophy region gene 1 binds Suv4-20h1 histone methyltransferase and impairs myogenesis. J Mol Cell Biol. 2013;5:294-307 pubmed 出版商
Albert M, Schmitz S, Kooistra S, Malatesta M, Morales Torres C, Rekling J, et al. The histone demethylase Jarid1b ensures faithful mouse development by protecting developmental genes from aberrant H3K4me3. PLoS Genet. 2013;9:e1003461 pubmed 出版商
Na J, Lee K, Kim H, Shin J, Na W, Jeong H, et al. Role of type II protein arginine methyltransferase 5 in the regulation of Circadian Per1 gene. PLoS ONE. 2012;7:e48152 pubmed 出版商
Palmisano I, Della Chiara G, D Ambrosio R, Huichalaf C, Brambilla P, Corbetta S, et al. Amino acid starvation induces reactivation of silenced transgenes and latent HIV-1 provirus via down-regulation of histone deacetylase 4 (HDAC4). Proc Natl Acad Sci U S A. 2012;109:E2284-93 pubmed 出版商
Tong K, Keller T, Hoffman C, Annunziato A. Schizosaccharomyces pombe Hat1 (Kat1) is associated with Mis16 and is required for telomeric silencing. Eukaryot Cell. 2012;11:1095-103 pubmed 出版商
Demmerle J, Koch A, Holaska J. The nuclear envelope protein emerin binds directly to histone deacetylase 3 (HDAC3) and activates HDAC3 activity. J Biol Chem. 2012;287:22080-8 pubmed 出版商
Mishra P, Au W, Choy J, Kuich P, Baker R, Foltz D, et al. Misregulation of Scm3p/HJURP causes chromosome instability in Saccharomyces cerevisiae and human cells. PLoS Genet. 2011;7:e1002303 pubmed 出版商
Ai N, Hu X, Ding F, Yu B, Wang H, Lu X, et al. Signal-induced Brd4 release from chromatin is essential for its role transition from chromatin targeting to transcriptional regulation. Nucleic Acids Res. 2011;39:9592-604 pubmed 出版商
Strålfors A, Walfridsson J, Bhuiyan H, Ekwall K. The FUN30 chromatin remodeler, Fft3, protects centromeric and subtelomeric domains from euchromatin formation. PLoS Genet. 2011;7:e1001334 pubmed 出版商
Ferenczy M, Ranayhossaini D, DeLuca N. Activities of ICP0 involved in the reversal of silencing of quiescent herpes simplex virus 1. J Virol. 2011;85:4993-5002 pubmed 出版商
Kapoor Vazirani P, Kagey J, Vertino P. SUV420H2-mediated H4K20 trimethylation enforces RNA polymerase II promoter-proximal pausing by blocking hMOF-dependent H4K16 acetylation. Mol Cell Biol. 2011;31:1594-609 pubmed 出版商
Ferenczy M, DeLuca N. Reversal of heterochromatic silencing of quiescent herpes simplex virus type 1 by ICP0. J Virol. 2011;85:3424-35 pubmed 出版商
Kapoor A, Goldberg M, Cumberland L, Ratnakumar K, Segura M, Emanuel P, et al. The histone variant macroH2A suppresses melanoma progression through regulation of CDK8. Nature. 2010;468:1105-9 pubmed 出版商
Kasper L, Lerach S, Wang J, Wu S, Jeevan T, Brindle P. CBP/p300 double null cells reveal effect of coactivator level and diversity on CREB transactivation. EMBO J. 2010;29:3660-72 pubmed 出版商
Revenko A, Kalashnikova E, Gemo A, Zou J, Chen H. Chromatin loading of E2F-MLL complex by cancer-associated coregulator ANCCA via reading a specific histone mark. Mol Cell Biol. 2010;30:5260-72 pubmed 出版商
Reynoird N, Schwartz B, Delvecchio M, Sadoul K, Meyers D, Mukherjee C, et al. Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains. EMBO J. 2010;29:2943-52 pubmed 出版商
Tribus M, Bauer I, Galehr J, Rieser G, Trojer P, Brosch G, et al. A novel motif in fungal class 1 histone deacetylases is essential for growth and development of Aspergillus. Mol Biol Cell. 2010;21:345-53 pubmed 出版商
Sahu G, Wang D, Chen C, Zhurkin V, Harrington R, Appella E, et al. p53 binding to nucleosomal DNA depends on the rotational positioning of DNA response element. J Biol Chem. 2010;285:1321-32 pubmed 出版商
Bumgarner S, Dowell R, Grisafi P, Gifford D, Fink G. Toggle involving cis-interfering noncoding RNAs controls variegated gene expression in yeast. Proc Natl Acad Sci U S A. 2009;106:18321-6 pubmed 出版商
Octavio L, Gedeon K, Maheshri N. Epigenetic and conventional regulation is distributed among activators of FLO11 allowing tuning of population-level heterogeneity in its expression. PLoS Genet. 2009;5:e1000673 pubmed 出版商
Lugrin J, Ding X, Le Roy D, Chanson A, Sweep F, Calandra T, et al. Histone deacetylase inhibitors repress macrophage migration inhibitory factor (MIF) expression by targeting MIF gene transcription through a local chromatin deacetylation. Biochim Biophys Acta. 2009;1793:1749-58 pubmed 出版商
Ellison Zelski S, Solodin N, Alarid E. Repression of ESR1 through actions of estrogen receptor alpha and Sin3A at the proximal promoter. Mol Cell Biol. 2009;29:4949-58 pubmed 出版商
Gad W, Kim Y. N-terminal tail of a viral histone H4 encoded in Cotesia plutellae bracovirus is essential to suppress gene expression of host histone H4. Insect Mol Biol. 2009;18:111-8 pubmed 出版商
产品信息
目录代码 :
05-858
亚类别 :
Epigenetics & Nuclear Function
产品名称 :
Anti-Histone H4 Antibody, pan, clone 62-141-13, rabbit monoclonal
产品类型 :
抗体
克隆性 :
单克隆抗体
基因编号 :
P62805
宿主名称 :
抗原 :
组蛋白H4
共轭标签 :
纯化
抗体亚型 :
IgG
产品描述 :
Anti-Histone H4 Antibody, pan, clone 62-141-13, rabbit monoclonal
交叉活性 :
Human;Chicken;Vertebrates;Yeast ( S. cerevisiae )
背景 :
Histone H4 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H4 is involved with the structure of the nucleosomes of the 'beads on a string' structure.
别名 :
H4;Histone H4;H4 histone family, member A;histone 1, H4a;histone cluster 1, H4a
免疫原 :
KLH-conjugated, synthetic peptide corresponding to amino acids 17-28 of Histone H4. Epitope has been mapped to residues 25-28.
特异性 :
Recognizes Histone H4, Mr 10 kDa.
包装尺寸 :
100微升
用途 :
Western Blotting;Multiplexing;ChIP-seq;Chromatin Immunoprecipitation (ChIP)
储存 :
收到之日起在2-8℃稳定1年
公司信息
默克密理博中国
上海市浦东张江高科技园区晨晖路88号2号楼2楼
asiatechserv@millipore.com
http://www.millipore.com/china/wwcn/cnhome
400-889-1988
公司总部: 美国
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

Hundreds of New Antibodies in the areas of:
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View all the new antibodies at www.emdmillipore.com.