This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
默克密理博中国
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
产品类型 :
抗体
产品名称 :
乙酰组蛋白H4抗体
目录 :
06-598
规格 :
200微克
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 非洲爪蛙
应用 :
免疫印迹, 染色质免疫沉淀
文章摘录数: 17
出版应用/物种/样本/稀释参考文献
  • 染色质免疫沉淀 ; 非洲爪蛙; 图 4
Tamaoki K, Okada R, Ishihara A, Shiojiri N, Mochizuki K, Goda T, et al. Morphological, biochemical, transcriptional and epigenetic responses to fasting and refeeding in intestine of Xenopus laevis. Cell Biosci. 2016;6:2 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Kelkar M, Senthilkumar K, Jadhav S, Gupta S, Ahn B, De A. Enhancement of human sodium iodide symporter gene therapy for breast cancer by HDAC inhibitor mediated transcriptional modulation. Sci Rep. 2016;6:19341 pubmed 出版商
Ma H, Xu J, Liu Y. WindSTORM: Robust online image processing for high-throughput nanoscopy. Sci Adv. 2019;5:eaaw0683 pubmed 出版商
Huai W, Liu X, Wang C, Zhang Y, Chen X, Chen X, et al. KAT8 selectively inhibits antiviral immunity by acetylating IRF3. J Exp Med. 2019;216:772-785 pubmed 出版商
Basilicata M, Bruel A, Semplicio G, Valsecchi C, Aktas T, Duffourd Y, et al. De novo mutations in MSL3 cause an X-linked syndrome marked by impaired histone H4 lysine 16 acetylation. Nat Genet. 2018;50:1442-1451 pubmed 出版商
Valsecchi C, Basilicata M, Semplicio G, Georgiev P, Gutierrez N, Akhtar A. Facultative dosage compensation of developmental genes on autosomes in Drosophila and mouse embryonic stem cells. Nat Commun. 2018;9:3626 pubmed 出版商
Lee B, Choi A, Kim J, Jun Y, Woo H, Ha S, et al. Rpd3L HDAC links H3K4me3 to transcriptional repression memory. Nucleic Acids Res. 2018;46:8261-8274 pubmed 出版商
Joo Y, Ficarro S, Soares L, Chun Y, Marto J, Buratowski S. Downstream promoter interactions of TFIID TAFs facilitate transcription reinitiation. Genes Dev. 2017;: pubmed 出版商
Acharya D, Hainer S, Yoon Y, Wang F, Bach I, Rivera Pérez J, et al. KAT-Independent Gene Regulation by Tip60 Promotes ESC Self-Renewal but Not Pluripotency. Cell Rep. 2017;19:671-679 pubmed 出版商
Nagaki K, Yamaji N, Murata M. ePro-ClearSee: a simple immunohistochemical method that does not require sectioning of plant samples. Sci Rep. 2017;7:42203 pubmed 出版商
Bulusu V, Tumanov S, Michalopoulou E, van den Broek N, Mackay G, Nixon C, et al. Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation. Cell Rep. 2017;18:647-658 pubmed 出版商
Xie J, Jenull S, Tscherner M, Kuchler K. The Paralogous Histone Deacetylases Rpd3 and Rpd31 Play Opposing Roles in Regulating the White-Opaque Switch in the Fungal Pathogen Candida albicans. MBio. 2016;7: pubmed 出版商
Cuella Martin R, Oliveira C, Lockstone H, Snellenberg S, Grolmusova N, Chapman J. 53BP1 Integrates DNA Repair and p53-Dependent Cell Fate Decisions via Distinct Mechanisms. Mol Cell. 2016;64:51-64 pubmed 出版商
Wei Y, Liu J, Villaescusa J, Aberg E, Brene S, Wegener G, et al. Elevation of Il6 is associated with disturbed let-7 biogenesis in a genetic model of depression. Transl Psychiatry. 2016;6:e869 pubmed 出版商
Lu Y, Liu Y, Liao S, Tu W, Shen Y, Yan Y, et al. Epigenetic modifications promote the expression of the orphan nuclear receptor NR0B1 in human lung adenocarcinoma cells. Oncotarget. 2016;7:43162-43176 pubmed 出版商
Kayama T, Mori M, Ito Y, Matsushima T, Nakamichi R, Suzuki H, et al. Gtf2ird1-Dependent Mohawk Expression Regulates Mechanosensing Properties of the Tendon. Mol Cell Biol. 2016;36:1297-309 pubmed 出版商
Clifford R, John A, Brightling C, Knox A. Abnormal histone methylation is responsible for increased vascular endothelial growth factor 165a secretion from airway smooth muscle cells in asthma. J Immunol. 2012;189:819-31 pubmed 出版商
产品信息
目录代码 :
06-598
亚类别 :
Epigenetics & Nuclear Function
产品名称 :
抗乙酰组蛋白H4抗体
产品类型 :
抗体
克隆性 :
多克隆抗体
基因编号 :
P62805
宿主名称 :
兔
抗原 :
乙酰组蛋白H4
共轭标签 :
纯化
抗体亚型 :
IgG
产品描述 :
抗乙酰组蛋白H4抗体
交叉活性 :
四膜虫;人类
背景 :
Histone H4 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H4 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Acetylation of histone H4 occurs at several different lysine positions in the histone tail and is performed by a family of enzymes known as Histone Acetyl Transferases (HATs).
别名 :
H4 histone family, member A;histone 1, H4a;histone cluster 1, H4a
免疫原 :
KLH-conjugated peptide corresponding to amino acids 2-19 of Tetrahymena histone H4 (AGG(Ac)KGG(Ac)KGMG(Ac)KVGA(Ac)KRHS-C), acetylated on lysines 5,8,12 and 16.
特异性 :
Recognizes acetylated histone H4. Cross-reacts with acetylated histone H2B from Tetrahymena and weakly cross-reacts with acetylated histone H2B from HeLa cells. May crossreact with other acetylated proteins.
包装尺寸 :
200微克
用途 :
免疫细胞化学;免疫沉淀;免疫印迹;染色质免疫沉淀 (ChIP)
储存 :
1 year at -20°C from date of shipment. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
公司信息
默克密理博中国
上海市浦东张江高科技园区晨晖路88号2号楼2楼
asiatechserv@millipore.com
http://www.millipore.com/china/wwcn/cnhome
400-889-1988
公司总部: 美国
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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