This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
默克密理博中国
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
产品类型 :
抗体
产品名称 :
乙酰组蛋白H3抗体
目录 :
06-599
规格 :
100微克
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
great pond snail, 人类, 小鼠, 大鼠, brewer's yeast
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 免疫组化-石蜡切片, ChIP-Seq, 其他
文章摘录数: 110
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 7b
Lamaa A, Humbert J, Aguirrebengoa M, Cheng X, Nicolas E, Cote J, et al. Integrated analysis of H2A.Z isoforms function reveals a complex interplay in gene regulation. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 小鼠; 图 2b
Qiu J, Villa M, Sanin D, Buck M, O Sullivan D, Ching R, et al. Acetate Promotes T Cell Effector Function during Glucose Restriction. Cell Rep. 2019;27:2063-2074.e5 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 1d
Song K, Kim J, Lee Y, Bae H, Lee H, Woo S, et al. Mitochondrial reprogramming via ATP5H loss promotes multimodal cancer therapy resistance. J Clin Invest. 2018;128:4098-4114 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠; 图 5d
Qin L, Ma K, Wang Z, Hu Z, Matas E, Wei J, et al. Social deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition. Nat Neurosci. 2018;21:564-575 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠; 1:20,000; 图 4h
Fu X, Zhang C, Meng H, Zhang K, Shi L, Cao C, et al. Oncoprotein Tudor-SN is a key determinant providing survival advantage under DNA damaging stress. Cell Death Differ. 2018;25:1625-1637 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠; 1:500; 图 7g
Meng Z, Tao W, Sun J, Wang Q, Mi L, Lin J. Uncoupling Exercise Bioenergetics From Systemic Metabolic Homeostasis by Conditional Inactivation of Baf60 in Skeletal Muscle. Diabetes. 2018;67:85-97 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 1c
Getz A, Xu F, Visser F, Persson R, Syed N. Tumor suppressor menin is required for subunit-specific nAChR α5 transcription and nAChR-dependent presynaptic facilitation in cultured mouse hippocampal neurons. Sci Rep. 2017;7:1768 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s3b
Coni S, Mancuso A, Di Magno L, Sdruscia G, Manni S, Serrao S, et al. Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma. Sci Rep. 2017;7:44079 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 6e
Chang Y, Lin T, Campbell M, Pan C, Lee S, Lee H, et al. REST is a crucial regulator for acquiring EMT-like and stemness phenotypes in hormone-refractory prostate cancer. Sci Rep. 2017;7:42795 pubmed 出版商
  • 染色质免疫沉淀 ; 大鼠; 表 1
Kumar A, Dumasia K, Deshpande S, Balasinor N. Direct regulation of genes involved in sperm release by estrogen and androgen through their receptors and coregulators. J Steroid Biochem Mol Biol. 2017;171:66-74 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Altieri F, Di Stadio C, Federico A, Miselli G, De Palma M, Rippa E, et al. Epigenetic alterations of gastrokine 1 gene expression in gastric cancer. Oncotarget. 2017;8:16899-16911 pubmed 出版商
  • 免疫印迹; brewer's yeast; 1:5000; 图 s1e
Young C, Hillyer C, Hokamp K, Fitzpatrick D, Konstantinov N, Welty J, et al. Distinct histone methylation and transcription profiles are established during the development of cellular quiescence in yeast. BMC Genomics. 2017;18:107 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 6b
Lin Y, Lin Y, Huang M, Kuo P, Wu C, Lee M, et al. Tumor necrosis factor-alpha inhibitors suppress CCL2 chemokine in monocytes via epigenetic modification. Mol Immunol. 2017;83:82-91 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3d
  • 免疫组化-石蜡切片; 小鼠; 1:500; 图 5c
Hennika T, Hu G, Olaciregui N, Barton K, Ehteda A, Chitranjan A, et al. Pre-Clinical Study of Panobinostat in Xenograft and Genetically Engineered Murine Diffuse Intrinsic Pontine Glioma Models. PLoS ONE. 2017;12:e0169485 pubmed 出版商
  • 免疫组化; 小鼠; 图 5b
  • 免疫印迹; 小鼠; 图 5a
Greene T, Tokuyama M, Knudsen G, Kunz M, Lin J, Greninger A, et al. A Herpesviral induction of RAE-1 NKG2D ligand expression occurs through release of HDAC mediated repression. elife. 2016;5: pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠; 图 7f
Bao K, Carr T, Wu J, Barclay W, Jin J, Ciofani M, et al. BATF Modulates the Th2 Locus Control Region and Regulates CD4+ T Cell Fate during Antihelminth Immunity. J Immunol. 2016;197:4371-4381 pubmed
  • 免疫印迹; 人类; 1:2000; 图 1a
Fournier M, Orpinell M, Grauffel C, Scheer E, Garnier J, Ye T, et al. KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification. Nat Commun. 2016;7:13227 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 s4b
Li S, Hu H, He Z, Liang D, Sun R, Lan K. Fine-Tuning of the Kaposi's Sarcoma-Associated Herpesvirus Life Cycle in Neighboring Cells through the RTA-JAG1-Notch Pathway. PLoS Pathog. 2016;12:e1005900 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 3i
Harrod A, Fulton J, Nguyen V, Periyasamy M, Ramos Garcia L, Lai C, et al. Genomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer. Oncogene. 2017;36:2286-2296 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠; 图 4a
  • 免疫印迹; 小鼠; 图 4f
Patrick N, Griggs C, Icenogle A, Gilpatrick M, Kadiyala V, Jaime Frias R, et al. Class I lysine deacetylases promote glucocorticoid-induced transcriptional repression through functional interaction with LSD1. J Steroid Biochem Mol Biol. 2017;167:1-13 pubmed 出版商
  • 染色质免疫沉淀 ; brewer's yeast; 图 2
Abraham K, Chan J, Salvi J, Ho B, Hall A, Vidya E, et al. Intersection of calorie restriction and magnesium in the suppression of genome-destabilizing RNA-DNA hybrids. Nucleic Acids Res. 2016;44:8870-8884 pubmed
  • 免疫印迹; 人类; 1:1000; 图 s09
Oudejans C, Poutsma A, Michel O, Thulluru H, Mulders J, van de Vrugt H, et al. Noncoding RNA-regulated gain-of-function of STOX2 in Finnish pre-eclamptic families. Sci Rep. 2016;6:32129 pubmed 出版商
  • 免疫印迹; great pond snail; 1:2000; 图 2
Getz A, Visser F, Bell E, Xu F, Flynn N, Zaidi W, et al. Two proteolytic fragments of menin coordinate the nuclear transcription and postsynaptic clustering of neurotransmitter receptors during synaptogenesis between Lymnaea neurons. Sci Rep. 2016;6:31779 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 6
Kang M, Park K, Yang J, Lee C, Oh S, Yun J, et al. miR-6734 Up-Regulates p21 Gene Expression and Induces Cell Cycle Arrest and Apoptosis in Colon Cancer Cells. PLoS ONE. 2016;11:e0160961 pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Ramakrishnan S, Ku S, Ciamporcero E, Miles K, Attwood K, Chintala S, et al. HDAC 1 and 6 modulate cell invasion and migration in clear cell renal cell carcinoma. BMC Cancer. 2016;16:617 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 4f
Rada M, Vasileva E, Lezina L, Marouco D, Antonov A, Macip S, et al. Human EHMT2/G9a activates p53 through methylation-independent mechanism. Oncogene. 2017;36:922-932 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5e,7b
Grinshtein N, Rioseco C, Marcellus R, UEHLING D, Aman A, Lun X, et al. Small molecule epigenetic screen identifies novel EZH2 and HDAC inhibitors that target glioblastoma brain tumor-initiating cells. Oncotarget. 2016;7:59360-59376 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 3a
  • 染色质免疫沉淀 ; 小鼠; 图 3a
  • 免疫印迹; 小鼠; 图 3c
Kang J, Park S, Jeong S, Han M, Lee C, Lee K, et al. Epigenetic regulation of Kcna3-encoding Kv1.3 potassium channel by cereblon contributes to regulation of CD4+ T-cell activation. Proc Natl Acad Sci U S A. 2016;113:8771-6 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 5
Kurg R, Reinsalu O, Jagur S, Ounap K, Võsa L, Kasvandik S, et al. Biochemical and proteomic characterization of retrovirus Gag based microparticles carrying melanoma antigens. Sci Rep. 2016;6:29425 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 st3
Gwak J, Shin J, Lee K, Hong S, Oh S, Goh S, et al. SFMBT2 (Scm-like with four mbt domains 2) negatively regulates cell migration and invasion in prostate cancer cells. Oncotarget. 2016;7:48250-48264 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 2
Chen D, Kluz T, Fang L, Zhang X, Sun H, Jin C, et al. Hexavalent Chromium (Cr(VI)) Down-Regulates Acetylation of Histone H4 at Lysine 16 through Induction of Stressor Protein Nupr1. PLoS ONE. 2016;11:e0157317 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Lin S, Wang B, Lin C, Chien P, Wu Y, Ko J, et al. Chidamide alleviates TGF-?-induced epithelial-mesenchymal transition in lung cancer cell lines. Mol Biol Rep. 2016;43:687-95 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 4
Alarcón V, Hernández S, Rubio L, Alvarez F, Flores Y, Varas Godoy M, et al. The enzymes LSD1 and Set1A cooperate with the viral protein HBx to establish an active hepatitis B viral chromatin state. Sci Rep. 2016;6:25901 pubmed 出版商
  • 免疫印迹; 人类; 图 1f
Devaiah B, Case Borden C, Gegonne A, Hsu C, Chen Q, Meerzaman D, et al. BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin. Nat Struct Mol Biol. 2016;23:540-8 pubmed 出版商
  • 免疫细胞化学; 人类; 1:400; 图 3
Douvaras P, Rusielewicz T, Kim K, Haines J, CASACCIA P, Fossati V. Epigenetic Modulation of Human Induced Pluripotent Stem Cell Differentiation to Oligodendrocytes. Int J Mol Sci. 2016;17: pubmed 出版商
  • 免疫沉淀; 小鼠; 图 8
Lee B, Lee S, Agulnick A, Lee J, Lee S. Single-stranded DNA binding proteins are required for LIM complexes to induce transcriptionally active chromatin and specify spinal neuronal identities. Development. 2016;143:1721-31 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠; 图 7
Gomez Rodriguez J, Meylan F, Handon R, Hayes E, Anderson S, Kirby M, et al. Itk is required for Th9 differentiation via TCR-mediated induction of IL-2 and IRF4. Nat Commun. 2016;7:10857 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 1c
Waldeck K, Cullinane C, Ardley K, Shortt J, Martin B, Tothill R, et al. Long term, continuous exposure to panobinostat induces terminal differentiation and long term survival in the TH-MYCN neuroblastoma mouse model. Int J Cancer. 2016;139:194-204 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠; 图 7
Hwang S, Jang S, Kim M, Kim L, Kim B, Kim H, et al. YY1 inhibits differentiation and function of regulatory T cells by blocking Foxp3 expression and activity. Nat Commun. 2016;7:10789 pubmed 出版商
  • 染色质免疫沉淀 ; 大鼠; 图 6
  • 免疫印迹; 大鼠; 1:1000; 图 2
Wei J, Xiong Z, Lee J, Cheng J, Duffney L, Matas E, et al. Histone Modification of Nedd4 Ubiquitin Ligase Controls the Loss of AMPA Receptors and Cognitive Impairment Induced by Repeated Stress. J Neurosci. 2016;36:2119-30 pubmed 出版商
  • 染色质免疫沉淀 ; brewer's yeast; 图 5
  • 免疫印迹; brewer's yeast; 图 5
Jones J, Singh P, Govind C. Recruitment of Saccharomyces cerevisiae Cmr1/Ydl156w to Coding Regions Promotes Transcription Genome Wide. PLoS ONE. 2016;11:e0148897 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s5
Zhang Q, Dan J, Wang H, Guo R, Mao J, Fu H, et al. Tcstv1 and Tcstv3 elongate telomeres of mouse ES cells. Sci Rep. 2016;6:19852 pubmed 出版商
  • 其他; 人类; 图 st1
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 3
M L, P P, T K, M P, E S, J P, et al. Essential role of HDAC6 in the regulation of PD-L1 in melanoma. Mol Oncol. 2016;10:735-750 pubmed 出版商
  • ChIP-Seq; 小鼠; 表  s3
Yasuma K, Yasunaga J, Takemoto K, Sugata K, Mitobe Y, Takenouchi N, et al. HTLV-1 bZIP Factor Impairs Anti-viral Immunity by Inducing Co-inhibitory Molecule, T Cell Immunoglobulin and ITIM Domain (TIGIT). PLoS Pathog. 2016;12:e1005372 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 s4
Terranova Barberio M, Roca M, Zotti A, Leone A, Bruzzese F, Vitagliano C, et al. Valproic acid potentiates the anticancer activity of capecitabine in vitro and in vivo in breast cancer models via induction of thymidine phosphorylase expression. Oncotarget. 2016;7:7715-31 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 2
Martínez Iglesias O, Alonso Merino E, Gómez Rey S, Velasco Martín J, Martín Orozco R, Luengo E, et al. Autoregulatory loop of nuclear corepressor 1 expression controls invasion, tumor growth, and metastasis. Proc Natl Acad Sci U S A. 2016;113:E328-37 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 s2
De Luca T, Pelosi A, Trisciuoglio D, D Aguanno S, Desideri M, Farini V, et al. miR-211 and MITF modulation by Bcl-2 protein in melanoma cells. Mol Carcinog. 2016;55:2304-2312 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 1e
Petroni M, Sardina F, Heil C, Sahún Roncero M, Colicchia V, Veschi V, et al. The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress. Cell Death Differ. 2016;23:197-206 pubmed 出版商
Palomer X, Román Azcona M, Pizarro Delgado J, Planavila A, Villarroya F, Valenzuela Alcaraz B, et al. SIRT3-mediated inhibition of FOS through histone H3 deacetylation prevents cardiac fibrosis and inflammation. Signal Transduct Target Ther. 2020;5:14 pubmed 出版商
Fan L, Xu S, Zhang F, Cui X, Fazli L, Gleave M, et al. Histone demethylase JMJD1A promotes expression of DNA repair factors and radio-resistance of prostate cancer cells. Cell Death Dis. 2020;11:214 pubmed 出版商
Vetreno R, Bohnsack J, Kusumo H, Liu W, Pandey S, Crews F. Neuroimmune and epigenetic involvement in adolescent binge ethanol-induced loss of basal forebrain cholinergic neurons: Restoration with voluntary exercise. Addict Biol. 2020;25:e12731 pubmed 出版商
Crochemore C, Fernandez Molina C, Montagne B, Salles A, Ricchetti M. CSB promoter downregulation via histone H3 hypoacetylation is an early determinant of replicative senescence. Nat Commun. 2019;10:5576 pubmed 出版商
Noce V, Battistelli C, Cozzolino A, Consalvi V, Cicchini C, Strippoli R, et al. YAP integrates the regulatory Snail/HNF4α circuitry controlling epithelial/hepatocyte differentiation. Cell Death Dis. 2019;10:768 pubmed 出版商
Liu Y, Bao C, Wang L, Han R, Beier U, Akimova T, et al. Complementary Roles of GCN5 and PCAF in Foxp3+ T-Regulatory Cells. Cancers (Basel). 2019;11: pubmed 出版商
Johansson J, Nászai M, Hodder M, Pickering K, Miller B, Ridgway R, et al. RAL GTPases Drive Intestinal Stem Cell Function and Regeneration through Internalization of WNT Signalosomes. Cell Stem Cell. 2019;24:592-607.e7 pubmed 出版商
Cui S, Li L, Yu R, Downes M, Evans R, Hulin J, et al. β-Catenin is essential for differentiation of primary myoblasts via cooperation with MyoD and α-catenin. Development. 2019;146: pubmed 出版商
Saeed U, Kim J, Piracha Z, Kwon H, Jung J, Chwae Y, et al. Parvulin 14 and Parvulin 17 Bind to HBx and cccDNA and Upregulate Hepatitis B Virus Replication from cccDNA to Virion in an HBx-Dependent Manner. J Virol. 2019;93: pubmed 出版商
Naik A, Byrd A, Lucander A, Krangel M. Hierarchical assembly and disassembly of a transcriptionally active RAG locus in CD4+CD8+ thymocytes. J Exp Med. 2019;216:231-243 pubmed 出版商
Kumar M, Kasti K, Balakrishnan L, Milavetz B. Directed Nucleosome Sliding during the Formation of the Simian Virus 40 Particle Exposes DNA Sequences Required for Early Transcription. J Virol. 2019;93: pubmed 出版商
Bahat A, Goldman A, Zaltsman Y, Khan D, Halperin C, Amzallag E, et al. MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells. Nat Commun. 2018;9:5132 pubmed 出版商
Yang C, Shen W, Chen H, Chu L, Xu Y, Zhou X, et al. Characterization and subcellular localization of histone deacetylases and their roles in response to abiotic stresses in soybean. BMC Plant Biol. 2018;18:226 pubmed 出版商
Jin H, Choi S, Kang M, Yun S, Kwon D, Noh Y, et al. Salicylic acid-induced transcriptional reprogramming by the HAC-NPR1-TGA histone acetyltransferase complex in Arabidopsis. Nucleic Acids Res. 2018;46:11712-11725 pubmed 出版商
Vandenbon A, Kumagai Y, Lin M, Suzuki Y, Nakai K. Waves of chromatin modifications in mouse dendritic cells in response to LPS stimulation. Genome Biol. 2018;19:138 pubmed 出版商
Pane L, Fulcoli F, Cirino A, Altomonte A, Ferrentino R, Bilio M, et al. Tbx1 represses Mef2c gene expression and is correlated with histone 3 deacetylation of the anterior heart field enhancer. Dis Model Mech. 2018;11: pubmed 出版商
de Bruyn Kops A, Burke J, Guthrie C. Brr6 plays a role in gene recruitment and transcriptional regulation at the nuclear envelope. Mol Biol Cell. 2018;29:2578-2590 pubmed 出版商
Hung F, Chen F, Li C, Chen C, Lai Y, Chen J, et al. The Arabidopsis LDL1/2-HDA6 histone modification complex is functionally associated with CCA1/LHY in regulation of circadian clock genes. Nucleic Acids Res. 2018;46:10669-10681 pubmed 出版商
Umeda M, Tsunekawa C, Senmatsu S, Asada R, Abe T, Ohta K, et al. Histone Chaperone Asf1 Is Required for the Establishment of Repressive Chromatin in Schizosaccharomyces pombe fbp1 Gene Repression. Mol Cell Biol. 2018;38: pubmed 出版商
Seeley J, Baker R, Mohamed G, Bruns T, Hayden M, Deshmukh S, et al. Induction of innate immune memory via microRNA targeting of chromatin remodelling factors. Nature. 2018;559:114-119 pubmed 出版商
Wang B, Yang X, Wang Y, Xie Y, Zhou X. Tomato Yellow Leaf Curl Virus V2 Interacts with Host Histone Deacetylase 6 To Suppress Methylation-Mediated Transcriptional Gene Silencing in Plants. J Virol. 2018;92: pubmed 出版商
Tanaka S, Jiang Y, Martinez G, Tanaka K, Yan X, Kurosaki T, et al. Trim33 mediates the proinflammatory function of Th17 cells. J Exp Med. 2018;215:1853-1868 pubmed 出版商
Ruiz L, Gurlo T, Ravier M, Wojtusciszyn A, Mathieu J, Brown M, et al. Proteasomal degradation of the histone acetyl transferase p300 contributes to beta-cell injury in a diabetes environment. Cell Death Dis. 2018;9:600 pubmed 出版商
Cai S, Song Y, Chen C, Shi J, Gan L. Natural chromatin is heterogeneous and self-associates in vitro. Mol Biol Cell. 2018;29:1652-1663 pubmed 出版商
Varshney D, Lombardi O, Schweikert G, Dunn S, Suska O, Cowling V. mRNA Cap Methyltransferase, RNMT-RAM, Promotes RNA Pol II-Dependent Transcription. Cell Rep. 2018;23:1530-1542 pubmed 出版商
Zhang J, He Z, Sen S, Wang F, Zhang Q, Sun Z. TCF-1 Inhibits IL-17 Gene Expression To Restrain Th17 Immunity in a Stage-Specific Manner. J Immunol. 2018;200:3397-3406 pubmed 出版商
Pasini A, Brand O, Jenkins G, Knox A, Pang L. Suberanilohydroxamic acid prevents TGF-β1-induced COX-2 repression in human lung fibroblasts post-transcriptionally by TIA-1 downregulation. Biochim Biophys Acta Gene Regul Mech. 2018;1861:463-472 pubmed 出版商
Wang S, Ko S, Kim Y, Jo S, Lee S, Jung S, et al. Capsaicin upregulates HDAC2 via TRPV1 and impairs neuronal maturation in mice. Exp Mol Med. 2018;50:e455 pubmed 出版商
Jing H, Su X, Gao B, Shuai Y, Chen J, Deng Z, et al. Epigenetic inhibition of Wnt pathway suppresses osteogenic differentiation of BMSCs during osteoporosis. Cell Death Dis. 2018;9:176 pubmed 出版商
Griggs C, Malm S, Jaime Frias R, Smith C. Valproic acid disrupts the oscillatory expression of core circadian rhythm transcription factors. Toxicol Appl Pharmacol. 2018;339:110-120 pubmed 出版商
Song S, Jeon M, Nam J, Kang J, Lee Y, Kang J, et al. Aberrant GATA2 epigenetic dysregulation induces a GATA2/GATA6 switch in human gastric cancer. Oncogene. 2018;37:993-1004 pubmed 出版商
Kirschner K, Sciesielski L, Krueger K, Scholz H. Wilms tumor protein-dependent transcription of VEGF receptor 2 and hypoxia regulate expression of the testis-promoting gene Sox9 in murine embryonic gonads. J Biol Chem. 2017;292:20281-20291 pubmed 出版商
Garcia Gomez A, Li T, Kerick M, Català Moll F, Comet N, Rodriguez Ubreva J, et al. TET2- and TDG-mediated changes are required for the acquisition of distinct histone modifications in divergent terminal differentiation of myeloid cells. Nucleic Acids Res. 2017;45:10002-10017 pubmed 出版商
Cao H, Zhang S, Shan S, Sun C, Li Y, Yu S, et al. Ligand-dependent corepressor (LCoR) represses the transcription factor C/EBPβ during early adipocyte differentiation. J Biol Chem. 2017;292:18973-18987 pubmed 出版商
Lyu Y, Nakano K, Davis R, Tepper C, Campbell M, Izumiya Y. ZIC2 Is Essential for Maintenance of Latency and Is a Target of an Immediate Early Protein during Kaposi's Sarcoma-Associated Herpesvirus Lytic Reactivation. J Virol. 2017;91: pubmed 出版商
Bohnsack J, Patel V, Morrow A. Ethanol Exposure Regulates Gabra1 Expression via Histone Deacetylation at the Promoter in Cultured Cortical Neurons. J Pharmacol Exp Ther. 2017;363:1-11 pubmed 出版商
Green A, Zhan L, Eid A, Zarbl H, Guo G, Richardson J. Valproate increases dopamine transporter expression through histone acetylation and enhanced promoter binding of Nurr1. Neuropharmacology. 2017;125:189-196 pubmed 出版商
Kishore A, Liang H, Kanchwala M, Xing C, Ganesh T, Akgul Y, et al. Prostaglandin dehydrogenase is a target for successful induction of cervical ripening. Proc Natl Acad Sci U S A. 2017;114:E6427-E6436 pubmed 出版商
Dong Y, Isono K, Ohbo K, Endo T, Ohara O, Maekawa M, et al. EPC1/TIP60-Mediated Histone Acetylation Facilitates Spermiogenesis in Mice. Mol Cell Biol. 2017;37: pubmed 出版商
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产品信息
目录代码 :
06-599
亚类别 :
Epigenetics & Nuclear Function
产品名称 :
抗乙酰组蛋白H3抗体
产品类型 :
抗体
克隆性 :
多克隆抗体
基因编号 :
Q16695
宿主名称 :
抗原 :
乙酰组蛋白H3
共轭标签 :
纯化
产品描述 :
抗乙酰组蛋白H3抗体
交叉活性 :
人类;小鼠;大鼠
背景 :
Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine. Acetylation of histone H3 occurs at several different lysine positions in the histone tail and is performed by a family of enzymes known as Histone Acetyl Transferases (HATs). Acetylation of lysine14 is commonly seen in genes that are being actively transcribed into RNA.
别名 :
H3 histone family, member T;histone 3, H3;histone cluster 3, H3
免疫原 :
Linear peptide corresponding to human Histone H3 acetylated at the N-terminus.
特异性 :
Recognizes Histone H3 acetylated at the N-terminus.
包装尺寸 :
100微克
用途 :
Western Blotting;Immunocytochemistry;ChIP-seq;Chromatin Immunoprecipitation (ChIP)
储存 :
收到之日起在2-8℃稳定1年
公司信息
默克密理博中国
上海市浦东张江高科技园区晨晖路88号2号楼2楼
asiatechserv@millipore.com
http://www.millipore.com/china/wwcn/cnhome
400-889-1988
公司总部: 美国
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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