Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

抗体

β-Catenin Antibody

06-734

200微克

多克隆

domestic rabbit

未共轭

Epigenetics & Nuclear Function

Anti-β-Catenin Antibody

抗体

多克隆抗体

P35222

兔

β-Catenin

纯化

IgG

Anti-β-Catenin Antibody

人类;大鼠;小鼠;兔;牛

β-catenin plays a central role in cell adhesion, bridging between cadherins and actin cytoskeleton. These activities are regulated through its differential interaction with several molecular partners, including cell-cell adherens junction (AJ) molecules, components of its degradation complex, and transcription factors. β-Catenin is composed of three domains: a central armadillo repeat domain and two N- and C-terminal tails. β-catenin can be phosphorylated by serine-threonine kinase, such as GSK-3. The phosphorylated β-catenin affects the protein association of β-catenin to E-cadherin and α-cateinin that occurs in the cell. This process can be reversed by de-phosphorylation of β-catenin.

catenin (cadherin-associated protein), beta 1 (88kD);catenin (cadherin-associated protein), beta 1 (88kDa);catenin (cadherin-associated protein), beta 1, 88kDa

KLH-conjugated, synthetic peptide (CGG-SYLDSGIHSGATTTAPSLSGK) corresponding to the consensus GSK3 phosphorylation site of human β -Catenin (amino acids 29-49).

Recognizes β-Catenin, Mr 92 kDa.

200微克

免疫细胞化学;免疫沉淀;免疫印迹

Stable for 1 year at 2-8°C from date of receipt. Handling Recommendations: Prior to removing the cap, centrifuge the vial and gently mix the solution.