| 出版应用/物种/样本/稀释 | 参考文献 |
|---|
- 免疫印迹; 人类; 图 s7a
- 免疫细胞化学; 小鼠; 图 6d
| Zhong J, Li X, Cai W, Wang Y, Dong S, Yang J, et al. TET1 modulates H4K16 acetylation by controlling auto-acetylation of hMOF to affect gene regulation and DNA repair function. Nucleic Acids Res. 2017;45:672-684 pubmed 出版商 |
| Cloutier J, Mahadevaiah S, Elinati E, Tóth A, Turner J. Mammalian meiotic silencing exhibits sexually dimorphic features. Chromosoma. 2016;125:215-26 pubmed 出版商 |
| Torres M, Pandita R, Kulak O, Kumar R, Formstecher E, Horikoshi N, et al. Role of the Exocyst Complex Component Sec6/8 in Genomic Stability. Mol Cell Biol. 2015;35:3633-45 pubmed 出版商 |
| Pefani D, Tognoli M, Pirincci Ercan D, Gorgoulis V, O Neill E. MST2 kinase suppresses rDNA transcription in response to DNA damage by phosphorylating nucleolar histone H2B. EMBO J. 2018;37: pubmed 出版商 |
| Cloutier J, Mahadevaiah S, Elinati E, Nussenzweig A, Tóth A, Turner J. Histone H2AFX Links Meiotic Chromosome Asynapsis to Prophase I Oocyte Loss in Mammals. PLoS Genet. 2015;11:e1005462 pubmed 出版商 |
| Moore Z, Chakrabarti G, Luo X, Ali A, Hu Z, Fattah F, et al. NAMPT inhibition sensitizes pancreatic adenocarcinoma cells to tumor-selective, PAR-independent metabolic catastrophe and cell death induced by β-lapachone. Cell Death Dis. 2015;6:e1599 pubmed 出版商 |
| Xiong X, Du Z, Wang Y, Feng Z, Fan P, Yan C, et al. 53BP1 promotes microhomology-mediated end-joining in G1-phase cells. Nucleic Acids Res. 2015;43:1659-70 pubmed 出版商 |
| Meisenberg C, Gilbert D, Chalmers A, Haley V, Gollins S, Ward S, et al. Clinical and cellular roles for TDP1 and TOP1 in modulating colorectal cancer response to irinotecan. Mol Cancer Ther. 2015;14:575-85 pubmed 出版商 |
| Ciccia A, Huang J, Izhar L, Sowa M, Harper J, Elledge S. Treacher Collins syndrome TCOF1 protein cooperates with NBS1 in the DNA damage response. Proc Natl Acad Sci U S A. 2014;111:18631-6 pubmed 出版商 |
| Wit N, Buoninfante O, van den Berk P, Jansen J, Hogenbirk M, de Wind N, et al. Roles of PCNA ubiquitination and TLS polymerases κ and η in the bypass of methyl methanesulfonate-induced DNA damage. Nucleic Acids Res. 2015;43:282-94 pubmed 出版商 |
| Chene G, Cayre A, Raoelfils I, Lagarde N, Dauplat J, Penault Llorca F. Morphological and immunohistochemical pattern of tubo-ovarian dysplasia and serous tubal intraepithelial carcinoma. Eur J Obstet Gynecol Reprod Biol. 2014;183:89-95 pubmed 出版商 |
| Cui L, Tse K, Zahedi P, Harding S, Zafarana G, Jaffray D, et al. Hypoxia and cellular localization influence the radiosensitizing effect of gold nanoparticles (AuNPs) in breast cancer cells. Radiat Res. 2014;182:475-88 pubmed 出版商 |
| Morgado Palacin L, Llanos S, Urbano Cuadrado M, Blanco Aparicio C, Megias D, Pastor J, et al. Non-genotoxic activation of p53 through the RPL11-dependent ribosomal stress pathway. Carcinogenesis. 2014;35:2822-30 pubmed 出版商 |
| Slaats G, Ghosh A, Falke L, Le Corre S, Shaltiël I, van de Hoek G, et al. Nephronophthisis-associated CEP164 regulates cell cycle progression, apoptosis and epithelial-to-mesenchymal transition. PLoS Genet. 2014;10:e1004594 pubmed 出版商 |
| Hu Y, Wang C, Huang K, Xia F, Parvin J, Mondal N. Regulation of 53BP1 protein stability by RNF8 and RNF168 is important for efficient DNA double-strand break repair. PLoS ONE. 2014;9:e110522 pubmed 出版商 |
| Li Z, Wang H, Wang Y, Murnane J, Dynan W. Effect of radiation quality on mutagenic joining of enzymatically-induced DNA double-strand breaks in previously irradiated human cells. Radiat Res. 2014;182:573-9 pubmed 出版商 |
| McQuade C, Al Zaki A, Desai Y, Vido M, Sakhuja T, Cheng Z, et al. A multifunctional nanoplatform for imaging, radiotherapy, and the prediction of therapeutic response. Small. 2015;11:834-43 pubmed 出版商 |
| Jackstadt R, Hermeking H. AP4 is required for mitogen- and c-MYC-induced cell cycle progression. Oncotarget. 2014;5:7316-27 pubmed |
| Sugahara R, Mon H, Lee J, Shiotsuki T, Kusakabe T. Differential contribution of the Fanconi anemia-related proteins to repair of several types of DNA damage in cultured silkworm cells. FEBS Lett. 2014;588:3959-63 pubmed 出版商 |
| Ishiguro K, Lin Z, Penketh P, Shyam K, Zhu R, Baumann R, et al. Distinct mechanisms of cell-kill by triapine and its terminally dimethylated derivative Dp44mT due to a loss or gain of activity of their copper(II) complexes. Biochem Pharmacol. 2014;91:312-22 pubmed 出版商 |
| Karnak D, Engelke C, Parsels L, Kausar T, Wei D, Robertson J, et al. Combined inhibition of Wee1 and PARP1/2 for radiosensitization in pancreatic cancer. Clin Cancer Res. 2014;20:5085-96 pubmed 出版商 |
| Dean R, Fam H, An J, Choi K, Shimizu Y, Jones S, et al. Identification of a putative Tdp1 inhibitor (CD00509) by in vitro and cell-based assays. J Biomol Screen. 2014;19:1372-82 pubmed 出版商 |
| Feng F, Speers C, Liu M, Jackson W, Moon D, Rinkinen J, et al. Targeted radiosensitization with PARP1 inhibition: optimization of therapy and identification of biomarkers of response in breast cancer. Breast Cancer Res Treat. 2014;147:81-94 pubmed 出版商 |
| Bartkova J, Hoei Hansen C, Krizova K, Hamerlik P, Skakkebæk N, Rajpert De Meyts E, et al. Patterns of DNA damage response in intracranial germ cell tumors versus glioblastomas reflect cell of origin rather than brain environment: implications for the anti-tumor barrier concept and treatment. Mol Oncol. 2014;8:1667-78 pubmed 出版商 |
| Park S, Kang J, Kim S, Kim H, Hong S, Lee Y, et al. Smad7 enhances ATM activity by facilitating the interaction between ATM and Mre11-Rad50-Nbs1 complex in DNA double-strand break repair. Cell Mol Life Sci. 2015;72:583-596 pubmed 出版商 |
| Jones R, Kotsantis P, Stewart G, Groth P, Petermann E. BRCA2 and RAD51 promote double-strand break formation and cell death in response to gemcitabine. Mol Cancer Ther. 2014;13:2412-21 pubmed 出版商 |
| Carlessi L, Fusar Poli E, Bechi G, Mantegazza M, Pascucci B, Narciso L, et al. Functional and molecular defects of hiPSC-derived neurons from patients with ATM deficiency. Cell Death Dis. 2014;5:e1342 pubmed 出版商 |
| Drutovic D, Chripkova M, Pilatova M, Kruzliak P, Perjesi P, Sarissky M, et al. Benzylidenetetralones, cyclic chalcone analogues, induce cell cycle arrest and apoptosis in HCT116 colorectal cancer cells. Tumour Biol. 2014;35:9967-75 pubmed 出版商 |
| Znojek P, Willmore E, Curtin N. Preferential potentiation of topoisomerase I poison cytotoxicity by PARP inhibition in S phase. Br J Cancer. 2014;111:1319-26 pubmed 出版商 |
| Manguan García C, Pintado Berninches L, Carrillo J, Machado Pinilla R, Sastre L, Perez Quilis C, et al. Expression of the genetic suppressor element 24.2 (GSE24.2) decreases DNA damage and oxidative stress in X-linked dyskeratosis congenita cells. PLoS ONE. 2014;9:e101424 pubmed 出版商 |
| Anderson D, Mirzayans R, Andrais B, Siegbahn E, Fallone B, Warkentin B. Spatial and temporal distribution of ?H2AX fluorescence in human cell cultures following synchrotron-generated X-ray microbeams: lack of correlation between persistent ?H2AX foci and apoptosis. J Synchrotron Radiat. 2014;21:801-10 pubmed 出版商 |
| Bridges K, Toniatti C, Buser C, Liu H, Buchholz T, Meyn R. Niraparib (MK-4827), a novel poly(ADP-Ribose) polymerase inhibitor, radiosensitizes human lung and breast cancer cells. Oncotarget. 2014;5:5076-86 pubmed |
| Glover K, Markell L, Donner E, Han X. Protein kinase C-activating tumor promoters modulate the DNA damage response in UVC-irradiated TK6 cells. Toxicol Lett. 2014;229:210-9 pubmed 出版商 |
| Cervelli T, Panetta D, Navarra T, Andreassi M, Basta G, Galli A, et al. Effects of single and fractionated low-dose irradiation on vascular endothelial cells. Atherosclerosis. 2014;235:510-8 pubmed 出版商 |
| Gao C, Bourke E, Scobie M, Famme M, Koolmeister T, Helleday T, et al. Rational design and validation of a Tip60 histone acetyltransferase inhibitor. Sci Rep. 2014;4:5372 pubmed 出版商 |
| Trapp Fragnet L, Bencherit D, Chabanne Vautherot D, Le Vern Y, Remy S, Boutet Robinet E, et al. Cell cycle modulation by Marek's disease virus: the tegument protein VP22 triggers S-phase arrest and DNA damage in proliferating cells. PLoS ONE. 2014;9:e100004 pubmed 出版商 |
| Cazzalini O, Sommatis S, Tillhon M, Dutto I, Bachi A, Rapp A, et al. CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis. Nucleic Acids Res. 2014;42:8433-48 pubmed 出版商 |
| Soriani A, Iannitto M, Ricci B, Fionda C, Malgarini G, Morrone S, et al. Reactive oxygen species- and DNA damage response-dependent NK cell activating ligand upregulation occurs at transcriptional levels and requires the transcriptional factor E2F1. J Immunol. 2014;193:950-60 pubmed 出版商 |
| Samuni Y, Wink D, Krishna M, Mitchell J, Goldstein S. Suberoylanilide hydroxamic acid radiosensitizes tumor hypoxic cells in vitro through the oxidation of nitroxyl to nitric oxide. Free Radic Biol Med. 2014;73:291-8 pubmed 出版商 |
| Dinami R, Ercolani C, Petti E, Piazza S, Ciani Y, Sestito R, et al. miR-155 drives telomere fragility in human breast cancer by targeting TRF1. Cancer Res. 2014;74:4145-56 pubmed 出版商 |
| Yang A, Rajeshkumar N, Wang X, Yabuuchi S, Alexander B, Chu G, et al. Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations. Cancer Discov. 2014;4:905-13 pubmed 出版商 |
| Patterson M, Sutton R, Forrest I, Sharrock R, Lane M, Kaufmann A, et al. Assessing the function of homologous recombination DNA repair in malignant pleural effusion (MPE) samples. Br J Cancer. 2014;111:94-100 pubmed 出版商 |
| Mason J, Logan H, Budke B, Wu M, Pawlowski M, Weichselbaum R, et al. The RAD51-stimulatory compound RS-1 can exploit the RAD51 overexpression that exists in cancer cells and tumors. Cancer Res. 2014;74:3546-55 pubmed 出版商 |
| Vidi P, Liu J, Salles D, Jayaraman S, Dorfman G, Gray M, et al. NuMA promotes homologous recombination repair by regulating the accumulation of the ISWI ATPase SNF2h at DNA breaks. Nucleic Acids Res. 2014;42:6365-79 pubmed 出版商 |
| Mizukami H, Takahashi K, Inaba W, Tsuboi K, Osonoi S, Yoshida T, et al. Involvement of oxidative stress-induced DNA damage, endoplasmic reticulum stress, and autophagy deficits in the decline of ?-cell mass in Japanese type 2 diabetic patients. Diabetes Care. 2014;37:1966-74 pubmed 出版商 |
| Shahar O, Kalousi A, Eini L, Fisher B, Weiss A, Darr J, et al. A high-throughput chemical screen with FDA approved drugs reveals that the antihypertensive drug Spironolactone impairs cancer cell survival by inhibiting homology directed repair. Nucleic Acids Res. 2014;42:5689-701 pubmed 出版商 |
| Al Ejeh F, Staudacher A, Smyth D, Darby J, Denoyer D, Tsopelas C, et al. Postchemotherapy and tumor-selective targeting with the La-specific DAB4 monoclonal antibody relates to apoptotic cell clearance. J Nucl Med. 2014;55:772-9 pubmed 出版商 |
| Mohni K, Kavanaugh G, Cortez D. ATR pathway inhibition is synthetically lethal in cancer cells with ERCC1 deficiency. Cancer Res. 2014;74:2835-45 pubmed 出版商 |
| Chang H, Wang H, Chen C, Hung T, Hou M, Yuan S, et al. 5-azacytidine induces anoikis, inhibits mammosphere formation and reduces metalloproteinase 9 activity in MCF-7 human breast cancer cells. Molecules. 2014;19:3149-59 pubmed 出版商 |
| Münch S, Weidtkamp Peters S, Klement K, Grigaravicius P, Monajembashi S, Salomoni P, et al. The tumor suppressor PML specifically accumulates at RPA/Rad51-containing DNA damage repair foci but is nonessential for DNA damage-induced fibroblast senescence. Mol Cell Biol. 2014;34:1733-46 pubmed 出版商 |
| Bokobza S, Jiang Y, Weber A, Devery A, Ryan A. Short-course treatment with gefitinib enhances curative potential of radiation therapy in a mouse model of human non-small cell lung cancer. Int J Radiat Oncol Biol Phys. 2014;88:947-54 pubmed 出版商 |
| Storm M, Kumpfmueller B, Bone H, Buchholz M, Sanchez Ripoll Y, Chaudhuri J, et al. Zscan4 is regulated by PI3-kinase and DNA-damaging agents and directly interacts with the transcriptional repressors LSD1 and CtBP2 in mouse embryonic stem cells. PLoS ONE. 2014;9:e89821 pubmed 出版商 |
| Morales J, Richard P, Rommel A, Fattah F, Motea E, Patidar P, et al. Kub5-Hera, the human Rtt103 homolog, plays dual functional roles in transcription termination and DNA repair. Nucleic Acids Res. 2014;42:4996-5006 pubmed 出版商 |
| Ramaekers C, van den Beucken T, Bristow R, Chiu R, Durocher D, Wouters B. RNF8-independent Lys63 poly-ubiquitylation prevents genomic instability in response to replication-associated DNA damage. PLoS ONE. 2014;9:e89997 pubmed 出版商 |
| Hosono Y, Abe T, Higuchi M, Kajii K, Sakuraba S, Tada S, et al. Tipin functions in the protection against topoisomerase I inhibitor. J Biol Chem. 2014;289:11374-84 pubmed 出版商 |
| Köpper F, Binkowski A, Bierwirth C, Dobbelstein M. The MAPK-activated protein kinase 2 mediates gemcitabine sensitivity in pancreatic cancer cells. Cell Cycle. 2014;13:884-9 pubmed 出版商 |
| Iacobazzi D, Mangialardi G, Gubernator M, Hofner M, Wielscher M, Vierlinger K, et al. Increased antioxidant defense mechanism in human adventitia-derived progenitor cells is associated with therapeutic benefit in ischemia. Antioxid Redox Signal. 2014;21:1591-604 pubmed 出版商 |
| Berkenkamp B, Susnik N, Baisantry A, Kuznetsova I, Jacobi C, Sörensen Zender I, et al. In vivo and in vitro analysis of age-associated changes and somatic cellular senescence in renal epithelial cells. PLoS ONE. 2014;9:e88071 pubmed 出版商 |
| Petrova N, Velichko A, Kantidze O, Razin S. Heat shock-induced dissociation of TRF2 from telomeres does not initiate a telomere-dependent DNA damage response. Cell Biol Int. 2014;38:675-81 pubmed 出版商 |
| Islam M, Thomas S, Murty V, Sedoris K, Miller D. c-Myc quadruplex-forming sequence Pu-27 induces extensive damage in both telomeric and nontelomeric regions of DNA. J Biol Chem. 2014;289:8521-31 pubmed 出版商 |
| Belanger F, Rajotte V, Drobetsky E. A majority of human melanoma cell lines exhibits an S phase-specific defect in excision of UV-induced DNA photoproducts. PLoS ONE. 2014;9:e85294 pubmed 出版商 |
| Morita A, Tanimoto K, Murakami T, Morinaga T, Hosoi Y. Mitochondria are required for ATM activation by extranuclear oxidative stress in cultured human hepatoblastoma cell line Hep G2 cells. Biochem Biophys Res Commun. 2014;443:1286-90 pubmed 出版商 |
| Khalaj M, Abbasi A, Yamanishi H, Akiyama K, Wakitani S, Kikuchi S, et al. A missense mutation in Rev7 disrupts formation of Pol?, impairing mouse development and repair of genotoxic agent-induced DNA lesions. J Biol Chem. 2014;289:3811-24 pubmed 出版商 |
| Ferlazzo M, Sonzogni L, Granzotto A, Bodgi L, Lartin O, Devic C, et al. Mutations of the Huntington's disease protein impact on the ATM-dependent signaling and repair pathways of the radiation-induced DNA double-strand breaks: corrective effect of statins and bisphosphonates. Mol Neurobiol. 2014;49:1200-11 pubmed 出版商 |
| Vitale N, Kisslinger A, Paladino S, Procaccini C, Matarese G, Pierantoni G, et al. Resveratrol couples apoptosis with autophagy in UVB-irradiated HaCaT cells. PLoS ONE. 2013;8:e80728 pubmed 出版商 |
| Frame F, Pellacani D, Collins A, Simms M, Mann V, Jones G, et al. HDAC inhibitor confers radiosensitivity to prostate stem-like cells. Br J Cancer. 2013;109:3023-33 pubmed 出版商 |
| Neumann J, Boerries M, Kohler R, Giaisi M, Krammer P, Busch H, et al. The natural anticancer compound rocaglamide selectively inhibits the G1-S-phase transition in cancer cells through the ATM/ATR-mediated Chk1/2 cell cycle checkpoints. Int J Cancer. 2014;134:1991-2002 pubmed 出版商 |
| Khongkow P, Karunarathna U, Khongkow M, Gong C, Gomes A, Yague E, et al. FOXM1 targets NBS1 to regulate DNA damage-induced senescence and epirubicin resistance. Oncogene. 2014;33:4144-55 pubmed 出版商 |
| Luo T, Cui S, Bian C, Yu X. Uhrf2 is important for DNA damage response in vascular smooth muscle cells. Biochem Biophys Res Commun. 2013;441:65-70 pubmed 出版商 |
| Secher T, Samba Louaka A, Oswald E, Nougayrede J. Escherichia coli producing colibactin triggers premature and transmissible senescence in mammalian cells. PLoS ONE. 2013;8:e77157 pubmed 出版商 |
| Helchowski C, Skow L, Roberts K, Chute C, Canman C. A small ubiquitin binding domain inhibits ubiquitin-dependent protein recruitment to DNA repair foci. Cell Cycle. 2013;12:3749-58 pubmed 出版商 |
| Hu L, Filippakis H, Huang H, Yen T, Gjoerup O. Replication stress and mitotic dysfunction in cells expressing simian virus 40 large T antigen. J Virol. 2013;87:13179-92 pubmed 出版商 |
| Wu Y, Deighan C, Miller B, Balasubramanian P, Lustberg M, Zborowski M, et al. Isolation and analysis of rare cells in the blood of cancer patients using a negative depletion methodology. Methods. 2013;64:169-82 pubmed 出版商 |
| Akiyama K, Noguchi J, Hirose M, Kajita S, Katayama K, Khalaj M, et al. A mutation in the nuclear pore complex gene Tmem48 causes gametogenesis defects in skeletal fusions with sterility (sks) mice. J Biol Chem. 2013;288:31830-41 pubmed 出版商 |
| Vassena L, Giuliani E, Matusali G, Cohen r, Doria M. The human immunodeficiency virus type 1 Vpr protein upregulates PVR via activation of the ATR-mediated DNA damage response pathway. J Gen Virol. 2013;94:2664-9 pubmed 出版商 |
| Men N, Kikuchi K, Nakai M, Fukuda A, Tanihara F, Noguchi J, et al. Effect of trehalose on DNA integrity of freeze-dried boar sperm, fertilization, and embryo development after intracytoplasmic sperm injection. Theriogenology. 2013;80:1033-44 pubmed 出版商 |
| Storci G, Bertoni S, De Carolis S, Papi A, Nati M, Ceccarelli C, et al. Slug/?-catenin-dependent proinflammatory phenotype in hypoxic breast cancer stem cells. Am J Pathol. 2013;183:1688-1697 pubmed 出版商 |
| Tu W, Li B, Huang B, Wang Y, Liu X, Guan H, et al. ?H2AX foci formation in the absence of DNA damage: mitotic H2AX phosphorylation is mediated by the DNA-PKcs/CHK2 pathway. FEBS Lett. 2013;587:3437-43 pubmed 出版商 |
| Iwasa H, Kudo T, Maimaiti S, Ikeda M, Maruyama J, Nakagawa K, et al. The RASSF6 tumor suppressor protein regulates apoptosis and the cell cycle via MDM2 protein and p53 protein. J Biol Chem. 2013;288:30320-9 pubmed 出版商 |
| Di Francesco A, De Pittà C, Moret F, Barbieri V, Celotti L, Mognato M. The DNA-damage response to ?-radiation is affected by miR-27a in A549 cells. Int J Mol Sci. 2013;14:17881-96 pubmed 出版商 |
| Yu L, Zhao Y, Quan C, Ji W, Zhu J, Huang Y, et al. Gemcitabine eliminates double minute chromosomes from human ovarian cancer cells. PLoS ONE. 2013;8:e71988 pubmed 出版商 |
| Chen Y, Kamili A, Hardy J, Groblewski G, Khanna K, Byrne J. Tumor protein D52 represents a negative regulator of ATM protein levels. Cell Cycle. 2013;12:3083-97 pubmed 出版商 |
| Lawrence M, Ormsby R, Blyth B, Bezak E, England G, Newman M, et al. Lack of high-dose radiation mediated prostate cancer promotion and low-dose radiation adaptive response in the TRAMP mouse model. Radiat Res. 2013;180:376-88 pubmed 出版商 |
| Cornelissen B, Waller A, Able S, Vallis K. Molecular radiotherapy using cleavable radioimmunoconjugates that target EGFR and ?H2AX. Mol Cancer Ther. 2013;12:2472-82 pubmed 出版商 |
| Lai X, Egan L. Suppression of radiation-induced DNA double-strand break repair by MyD88 is accompanied by apoptosis and crypt loss in mouse colon. Oncogenesis. 2013;2:e62 pubmed 出版商 |
| Postel Vinay S, Bajrami I, Friboulet L, Elliott R, Fontebasso Y, Dorvault N, et al. A high-throughput screen identifies PARP1/2 inhibitors as a potential therapy for ERCC1-deficient non-small cell lung cancer. Oncogene. 2013;32:5377-87 pubmed 出版商 |
| Orim F, Bychkov A, Shimamura M, Nakashima M, Ito M, Matsuse M, et al. Thyrotropin signaling confers more aggressive features with higher genomic instability on BRAF(V600E)-induced thyroid tumors in a mouse model. Thyroid. 2014;24:502-10 pubmed 出版商 |
| Butin Israeli V, Adam S, Goldman R. Regulation of nucleotide excision repair by nuclear lamin b1. PLoS ONE. 2013;8:e69169 pubmed 出版商 |
| Wells C, Bhaskara S, Stengel K, Zhao Y, Sirbu B, Chagot B, et al. Inhibition of histone deacetylase 3 causes replication stress in cutaneous T cell lymphoma. PLoS ONE. 2013;8:e68915 pubmed 出版商 |
| Bee L, Fabris S, Cherubini R, Mognato M, Celotti L. The efficiency of homologous recombination and non-homologous end joining systems in repairing double-strand breaks during cell cycle progression. PLoS ONE. 2013;8:e69061 pubmed 出版商 |
| Lin T, Ibrahim W, Peng C, Finegold M, Tsai R. A novel role of nucleostemin in maintaining the genome integrity of dividing hepatocytes during mouse liver development and regeneration. Hepatology. 2013;58:2176-87 pubmed 出版商 |
| Del Turco S, Ciofani G, Cappello V, Gemmi M, Cervelli T, Saponaro C, et al. Cytocompatibility evaluation of glycol-chitosan coated boron nitride nanotubes in human endothelial cells. Colloids Surf B Biointerfaces. 2013;111:142-9 pubmed 出版商 |
| Streppel M, Pai S, Campbell N, Hu C, Yabuuchi S, Canto M, et al. MicroRNA 223 is upregulated in the multistep progression of Barrett's esophagus and modulates sensitivity to chemotherapy by targeting PARP1. Clin Cancer Res. 2013;19:4067-78 pubmed 出版商 |
| Somaiah N, Yarnold J, Lagerqvist A, Rothkamm K, Helleday T. Homologous recombination mediates cellular resistance and fraction size sensitivity to radiation therapy. Radiother Oncol. 2013;108:155-61 pubmed 出版商 |
| Millet P, Granotier C, Etienne O, Boussin F. Radiation-induced upregulation of telomerase activity escapes PI3-kinase inhibition in two malignant glioma cell lines. Int J Oncol. 2013;43:375-82 pubmed 出版商 |
| Li Z, Hudson F, Wang H, Wang Y, Bian Z, Murnane J, et al. Increased mutagenic joining of enzymatically-induced DNA double-strand breaks in high-charge and energy particle irradiated human cells. Radiat Res. 2013;180:17-24 pubmed 出版商 |
| Li B, Shang Z, Yin J, Xu Q, Liu X, Wang Y, et al. PIG3 functions in DNA damage response through regulating DNA-PKcs homeostasis. Int J Biol Sci. 2013;9:425-34 pubmed 出版商 |
| Ulukaya E, Frame F, Cevatemre B, Pellacani D, Walker H, Mann V, et al. Differential cytotoxic activity of a novel palladium-based compound on prostate cell lines, primary prostate epithelial cells and prostate stem cells. PLoS ONE. 2013;8:e64278 pubmed 出版商 |
| Mahen R, Hattori H, Lee M, Sharma P, Jeyasekharan A, Venkitaraman A. A-type lamins maintain the positional stability of DNA damage repair foci in mammalian nuclei. PLoS ONE. 2013;8:e61893 pubmed 出版商 |
| Ryu S, Kawamura R, Naka R, Silberberg Y, Nakamura N, Nakamura C. Nanoneedle insertion into the cell nucleus does not induce double-strand breaks in chromosomal DNA. J Biosci Bioeng. 2013;116:391-6 pubmed 出版商 |
| Muller I, Merk B, Voss K, Averbeck N, Jakob B, Durante M, et al. Species conserved DNA damage response at the inactive human X chromosome. Mutat Res. 2013;756:30-6 pubmed 出版商 |
| Kopova I, Bacakova L, Lavrentiev V, Vacik J. Growth and potential damage of human bone-derived cells on fresh and aged fullerene c60 films. Int J Mol Sci. 2013;14:9182-204 pubmed 出版商 |
| Meyer B, Voss K, Tobias F, Jakob B, Durante M, Taucher Scholz G. Clustered DNA damage induces pan-nuclear H2AX phosphorylation mediated by ATM and DNA-PK. Nucleic Acids Res. 2013;41:6109-18 pubmed 出版商 |
| Sorokina S, Markova E, Gursky J, Dobrovodsky J, Belyaev I. Relative biological efficiency of protons at low and therapeutic doses in induction of 53BP1/?H2AX foci in lymphocytes from umbilical cord blood. Int J Radiat Biol. 2013;89:716-23 pubmed 出版商 |
| Lu X, Parvathaneni S, Hara T, Lal A, Sharma S. Replication stress induces specific enrichment of RECQ1 at common fragile sites FRA3B and FRA16D. Mol Cancer. 2013;12:29 pubmed 出版商 |
| Chene G, Tchirkov A, Pierre Eymard E, Dauplat J, Raoelfils I, Cayre A, et al. Early telomere shortening and genomic instability in tubo-ovarian preneoplastic lesions. Clin Cancer Res. 2013;19:2873-82 pubmed 出版商 |
| Bahassi E, Li Y, Wise Draper T, Deng L, Wang J, Darnell C, et al. A patient-derived somatic mutation in the epidermal growth factor receptor ligand-binding domain confers increased sensitivity to cetuximab in head and neck cancer. Eur J Cancer. 2013;49:2345-55 pubmed 出版商 |
| Saha A, Kappes F, Mundade A, Deutzmann A, Rosmarin D, Legendre M, et al. Intercellular trafficking of the nuclear oncoprotein DEK. Proc Natl Acad Sci U S A. 2013;110:6847-52 pubmed 出版商 |
| Min A, Im S, Yoon Y, Song S, Nam H, Hur H, et al. RAD51C-deficient cancer cells are highly sensitive to the PARP inhibitor olaparib. Mol Cancer Ther. 2013;12:865-77 pubmed 出版商 |
| Berchtold C, Coughlin A, Kasper Z, Thibeault S. Paracrine potential of fibroblasts exposed to cigarette smoke extract with vascular growth factor induction. Laryngoscope. 2013;123:2228-36 pubmed 出版商 |
| Jelveh S, Kaspler P, Bhogal N, Mahmood J, Lindsay P, Okunieff P, et al. Investigations of antioxidant-mediated protection and mitigation of radiation-induced DNA damage and lipid peroxidation in murine skin. Int J Radiat Biol. 2013;89:618-27 pubmed 出版商 |
| Jha H, Upadhyay S, A J Prasad M, Lu J, Cai Q, Saha A, et al. H2AX phosphorylation is important for LANA-mediated Kaposi's sarcoma-associated herpesvirus episome persistence. J Virol. 2013;87:5255-69 pubmed 出版商 |
| Ma H, Pederson T. The nucleolus stress response is coupled to an ATR-Chk1-mediated G2 arrest. Mol Biol Cell. 2013;24:1334-42 pubmed 出版商 |
| Lawrence M, Blyth B, Ormsby R, Tilley W, Sykes P. False-positive TUNEL staining observed in SV40 based transgenic murine prostate cancer models. Transgenic Res. 2013;22:1037-47 pubmed 出版商 |
| Okamoto K, Bartocci C, Ouzounov I, Diedrich J, Yates J, Denchi E. A two-step mechanism for TRF2-mediated chromosome-end protection. Nature. 2013;494:502-5 pubmed 出版商 |
| Renaud E, Rosselli F. FANC pathway promotes UV-induced stalled replication forks recovery by acting both upstream and downstream Pol? and Rev1. PLoS ONE. 2013;8:e53693 pubmed 出版商 |
| Karan T, Moiseenko V, Gill B, Horwood R, Kyle A, Minchinton A. Radiobiological effects of altering dose rate in filter-free photon beams. Phys Med Biol. 2013;58:1075-82 pubmed 出版商 |
| Rass E, Chandramouly G, Zha S, Alt F, Xie A. Ataxia telangiectasia mutated (ATM) is dispensable for endonuclease I-SceI-induced homologous recombination in mouse embryonic stem cells. J Biol Chem. 2013;288:7086-95 pubmed 出版商 |
| Lin R, Ho C, Liu L, Lyu Y. Topoisomerase II? deficiency enhances camptothecin-induced apoptosis. J Biol Chem. 2013;288:7182-92 pubmed 出版商 |
| Fischer B, Wong J, Degan S, Kummarapurugu A, Zheng S, Haridass P, et al. Increased expression of senescence markers in cystic fibrosis airways. Am J Physiol Lung Cell Mol Physiol. 2013;304:L394-400 pubmed 出版商 |
| Zimmermann M, Lottersberger F, Buonomo S, Sfeir A, de Lange T. 53BP1 regulates DSB repair using Rif1 to control 5' end resection. Science. 2013;339:700-4 pubmed 出版商 |
| Konishi T, Oikawa M, Suya N, Ishikawa T, Maeda T, Kobayashi A, et al. SPICE-NIRS microbeam: a focused vertical system for proton irradiation of a single cell for radiobiological research. J Radiat Res. 2013;54:736-47 pubmed 出版商 |
| Wu L, Shao L, Li M, Zheng J, Wang J, Feng W, et al. BMS-345541 sensitizes MCF-7 breast cancer cells to ionizing radiation by selective inhibition of homologous recombinational repair of DNA double-strand breaks. Radiat Res. 2013;179:160-70 pubmed 出版商 |
| Montenegro M, Sáez Ayala M, Piñero Madrona A, Cabezas Herrera J, Rodriguez Lopez J. Reactivation of the tumour suppressor RASSF1A in breast cancer by simultaneous targeting of DNA and E2F1 methylation. PLoS ONE. 2012;7:e52231 pubmed 出版商 |
| Subramanian C, Hada M, Opipari A, Castle V, Kwok R. CREB-binding protein regulates Ku70 acetylation in response to ionization radiation in neuroblastoma. Mol Cancer Res. 2013;11:173-81 pubmed 出版商 |
| Dvorakova M, Karafiat V, Pajer P, Kluzáková E, Jarkovska K, Pekova S, et al. DNA released by leukemic cells contributes to the disruption of the bone marrow microenvironment. Oncogene. 2013;32:5201-9 pubmed 出版商 |
| Jullien L, Mestre M, Roux P, Gire V. Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response. Nucleic Acids Res. 2013;41:900-11 pubmed 出版商 |
| Haro K, Sheth A, Scheinberg D. Dysregulation of IRP1-mediated iron metabolism causes gamma ray-specific radioresistance in leukemia cells. PLoS ONE. 2012;7:e48841 pubmed 出版商 |
| Tsai Y, Yeh C, Tzen K, Ho P, Tuan T, Pu Y, et al. Targeting epidermal growth factor receptor/human epidermal growth factor receptor 2 signalling pathway by a dual receptor tyrosine kinase inhibitor afatinib for radiosensitisation in murine bladder carcinoma. Eur J Cancer. 2013;49:1458-66 pubmed 出版商 |
| Kotova N, Vare D, Schultz N, Gradecka Meesters D, Stepnik M, Grawe J, et al. Genotoxicity of alcohol is linked to DNA replication-associated damage and homologous recombination repair. Carcinogenesis. 2013;34:325-30 pubmed 出版商 |
| Conradt L, Henrich A, Wirth M, Reichert M, Lesina M, Algül H, et al. Mdm2 inhibitors synergize with topoisomerase II inhibitors to induce p53-independent pancreatic cancer cell death. Int J Cancer. 2013;132:2248-57 pubmed 出版商 |
| Solarczyk K, Zarebski M, Dobrucki J. Inducing local DNA damage by visible light to study chromatin repair. DNA Repair (Amst). 2012;11:996-1002 pubmed 出版商 |
| Garm C, Moreno Villanueva M, Bürkle A, Petersen I, Bohr V, Christensen K, et al. Age and gender effects on DNA strand break repair in peripheral blood mononuclear cells. Aging Cell. 2013;12:58-66 pubmed 出版商 |
| Kalev P, Simíček M, Vázquez I, Munck S, Chen L, Soin T, et al. Loss of PPP2R2A inhibits homologous recombination DNA repair and predicts tumor sensitivity to PARP inhibition. Cancer Res. 2012;72:6414-24 pubmed 出版商 |
| Gallagher S, Kofman A, Huszar J, Dannenberg J, Depinho R, Braun R, et al. Distinct requirements for Sin3a in perinatal male gonocytes and differentiating spermatogonia. Dev Biol. 2013;373:83-94 pubmed 出版商 |
| Coffey K, Blackburn T, Cook S, Golding B, Griffin R, Hardcastle I, et al. Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer. PLoS ONE. 2012;7:e45539 pubmed 出版商 |
| Neumayer G, Helfricht A, Shim S, Le H, Lundin C, Belzil C, et al. Targeting protein for xenopus kinesin-like protein 2 (TPX2) regulates ?-histone 2AX (?-H2AX) levels upon ionizing radiation. J Biol Chem. 2012;287:42206-22 pubmed 出版商 |
| Grecchi S, Mazzini G, Lisa A, Armentero M, Bergamaschi R, Romani A, et al. Search for cellular stress biomarkers in lymphocytes from patients with multiple sclerosis: a pilot study. PLoS ONE. 2012;7:e44935 pubmed 出版商 |
| Arango D, Parihar A, Villamena F, Wang L, Freitas M, Grotewold E, et al. Apigenin induces DNA damage through the PKC?-dependent activation of ATM and H2AX causing down-regulation of genes involved in cell cycle control and DNA repair. Biochem Pharmacol. 2012;84:1571-80 pubmed 出版商 |
| Fedor Y, Vignard J, Nicolau Travers M, Boutet Robinet E, Watrin C, Salles B, et al. From single-strand breaks to double-strand breaks during S-phase: a new mode of action of the Escherichia coli Cytolethal Distending Toxin. Cell Microbiol. 2013;15:1-15 pubmed 出版商 |
| Baritaud M, Cabon L, Delavallée L, Galán Malo P, Gilles M, Brunelle Navas M, et al. AIF-mediated caspase-independent necroptosis requires ATM and DNA-PK-induced histone H2AX Ser139 phosphorylation. Cell Death Dis. 2012;3:e390 pubmed 出版商 |
| Beck H, Nähse Kumpf V, Larsen M, O Hanlon K, Patzke S, Holmberg C, et al. Cyclin-dependent kinase suppression by WEE1 kinase protects the genome through control of replication initiation and nucleotide consumption. Mol Cell Biol. 2012;32:4226-36 pubmed |
| Schmidt E, Nilsson O, Koskela A, Tuukkanen J, Ohlsson C, Rozell B, et al. Expression of the Hutchinson-Gilford progeria mutation during osteoblast development results in loss of osteocytes, irregular mineralization, and poor biomechanical properties. J Biol Chem. 2012;287:33512-22 pubmed |
| Nguyen C, Possemato R, Bauerlein E, Xie A, Scully R, Hahn W. Nek4 regulates entry into replicative senescence and the response to DNA damage in human fibroblasts. Mol Cell Biol. 2012;32:3963-77 pubmed 出版商 |
| Haro K, Scott A, Scheinberg D. Mechanisms of resistance to high and low linear energy transfer radiation in myeloid leukemia cells. Blood. 2012;120:2087-97 pubmed 出版商 |
| Hiller B, Achleitner M, Glage S, Naumann R, Behrendt R, Roers A. Mammalian RNase H2 removes ribonucleotides from DNA to maintain genome integrity. J Exp Med. 2012;209:1419-26 pubmed 出版商 |
| Braun H, Schmidt B, Raiss M, Baisantry A, Mircea Constantin D, Wang S, et al. Cellular senescence limits regenerative capacity and allograft survival. J Am Soc Nephrol. 2012;23:1467-73 pubmed 出版商 |
| Brizuela L, Ader I, Mazerolles C, Bocquet M, Malavaud B, Cuvillier O. First evidence of sphingosine 1-phosphate lyase protein expression and activity downregulation in human neoplasm: implication for resistance to therapeutics in prostate cancer. Mol Cancer Ther. 2012;11:1841-51 pubmed 出版商 |
| Li Y, Xiong H, Yang D. Functional switching of ATM: sensor of DNA damage in proliferating cells and mediator of Akt survival signal in post-mitotic human neuron-like cells. Chin J Cancer. 2012;31:364-72 pubmed 出版商 |
| Mauro M, Rego M, Boisvert R, Esashi F, Cavallo F, Jasin M, et al. p21 promotes error-free replication-coupled DNA double-strand break repair. Nucleic Acids Res. 2012;40:8348-60 pubmed |
| Tichy E, Pillai R, Deng L, Tischfield J, Hexley P, Babcock G, et al. The abundance of Rad51 protein in mouse embryonic stem cells is regulated at multiple levels. Stem Cell Res. 2012;9:124-34 pubmed 出版商 |
| Hardee M, Marciscano A, Medina Ramirez C, Zagzag D, Narayana A, Lonning S, et al. Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-?. Cancer Res. 2012;72:4119-29 pubmed 出版商 |
| Landau H, McNeely S, Nair J, Comenzo R, Asai T, Friedman H, et al. The checkpoint kinase inhibitor AZD7762 potentiates chemotherapy-induced apoptosis of p53-mutated multiple myeloma cells. Mol Cancer Ther. 2012;11:1781-8 pubmed 出版商 |
| Yang J, O Donnell L, Durocher D, Brown G. RMI1 promotes DNA replication fork progression and recovery from replication fork stress. Mol Cell Biol. 2012;32:3054-64 pubmed 出版商 |
| Turinetto V, Orlando L, Sanchez Ripoll Y, Kumpfmueller B, Storm M, Porcedda P, et al. High basal ?H2AX levels sustain self-renewal of mouse embryonic and induced pluripotent stem cells. Stem Cells. 2012;30:1414-23 pubmed 出版商 |
| Sanz Garcia M, Monsalve D, Sevilla A, Lazo P. Vaccinia-related kinase 1 (VRK1) is an upstream nucleosomal kinase required for the assembly of 53BP1 foci in response to ionizing radiation-induced DNA damage. J Biol Chem. 2012;287:23757-68 pubmed 出版商 |
| Fenske A, Glaesener S, Bokemeyer C, Thomale J, Dahm Daphi J, Honecker F, et al. Cisplatin resistance induced in germ cell tumour cells is due to reduced susceptibility towards cell death but not to altered DNA damage induction or repair. Cancer Lett. 2012;324:171-8 pubmed 出版商 |
| Meise R, Tomicic M, Kaina B, Christmann M. The chloroethylating anticancer drug ACNU induces FRA1 that is involved in drug resistance of glioma cells. Biochim Biophys Acta. 2012;1823:1199-207 pubmed 出版商 |
| Kudo T, Ikeda M, Nishikawa M, Yang Z, Ohno K, Nakagawa K, et al. The RASSF3 candidate tumor suppressor induces apoptosis and G1-S cell-cycle arrest via p53. Cancer Res. 2012;72:2901-11 pubmed 出版商 |
| Duxin J, Moore H, Sidorova J, Karanja K, Honaker Y, Dao B, et al. Okazaki fragment processing-independent role for human Dna2 enzyme during DNA replication. J Biol Chem. 2012;287:21980-91 pubmed 出版商 |
| Kang K, Zhu C, Wong Y, Gao Q, Ty A, Wong M. Gefitinib radiosensitizes stem-like glioma cells: inhibition of epidermal growth factor receptor-Akt-DNA-PK signaling, accompanied by inhibition of DNA double-strand break repair. Int J Radiat Oncol Biol Phys. 2012;83:e43-52 pubmed 出版商 |
| Huang F, Chang C, Wang J, Chang T, Lin J. Induction of senescence in cancer cells by the G-quadruplex stabilizer, BMVC4, is independent of its telomerase inhibitory activity. Br J Pharmacol. 2012;167:393-406 pubmed 出版商 |
| Kohzaki M, Chiourea M, Versini G, Adachi N, Takeda S, Gagos S, et al. The helicase domain and C-terminus of human RecQL4 facilitate replication elongation on DNA templates damaged by ionizing radiation. Carcinogenesis. 2012;33:1203-10 pubmed 出版商 |
| Thiemann M, Oertel S, Ehemann V, Weichert W, Stenzinger A, Bischof M, et al. In vivo efficacy of the histone deacetylase inhibitor suberoylanilide hydroxamic acid in combination with radiotherapy in a malignant rhabdoid tumor mouse model. Radiat Oncol. 2012;7:52 pubmed 出版商 |
| Harding S, Bristow R. Discordance between phosphorylation and recruitment of 53BP1 in response to DNA double-strand breaks. Cell Cycle. 2012;11:1432-44 pubmed 出版商 |
| Punchihewa C, Inoue A, Hishiki A, Fujikawa Y, Connelly M, Evison B, et al. Identification of small molecule proliferating cell nuclear antigen (PCNA) inhibitor that disrupts interactions with PIP-box proteins and inhibits DNA replication. J Biol Chem. 2012;287:14289-300 pubmed 出版商 |
| Sergent J, Paget V, Chevillard S. Toxicity and genotoxicity of nano-SiO2 on human epithelial intestinal HT-29 cell line. Ann Occup Hyg. 2012;56:622-30 pubmed 出版商 |
| Sultana R, McNeill D, Abbotts R, Mohammed M, Zdzienicka M, Qutob H, et al. Synthetic lethal targeting of DNA double-strand break repair deficient cells by human apurinic/apyrimidinic endonuclease inhibitors. Int J Cancer. 2012;131:2433-44 pubmed 出版商 |
| Freije A, Ceballos L, Coisy M, Barnes L, Rosa M, de Diego E, et al. Cyclin E drives human keratinocyte growth into differentiation. Oncogene. 2012;31:5180-92 pubmed 出版商 |
| Brzozowska K, Pinkawa M, Eble M, Müller W, Wojcik A, Kriehuber R, et al. In vivo versus in vitro individual radiosensitivity analysed in healthy donors and in prostate cancer patients with and without severe side effects after radiotherapy. Int J Radiat Biol. 2012;88:405-13 pubmed 出版商 |
| Lange S, Wittschieben J, Wood R. DNA polymerase zeta is required for proliferation of normal mammalian cells. Nucleic Acids Res. 2012;40:4473-82 pubmed 出版商 |
| Zumer K, Low A, Jiang H, Saksela K, Peterlin B. Unmodified histone H3K4 and DNA-dependent protein kinase recruit autoimmune regulator to target genes. Mol Cell Biol. 2012;32:1354-62 pubmed 出版商 |
| Kibe R, Zhang S, Guo D, Marrero L, Tsien F, Rodriguez P, et al. IL-7R? deficiency in p53null mice exacerbates thymocyte telomere erosion and lymphomagenesis. Cell Death Differ. 2012;19:1139-51 pubmed 出版商 |
| Runge R, Hiemann R, Wendisch M, Kasten Pisula U, Storch K, Zophel K, et al. Fully automated interpretation of ionizing radiation-induced ?H2AX foci by the novel pattern recognition system AKLIDES®. Int J Radiat Biol. 2012;88:439-47 pubmed 出版商 |
| Quanz M, Herbette A, Sayarath M, de Koning L, Dubois T, Sun J, et al. Heat shock protein 90? (Hsp90?) is phosphorylated in response to DNA damage and accumulates in repair foci. J Biol Chem. 2012;287:8803-15 pubmed 出版商 |
| Algire C, Moiseeva O, Deschênes Simard X, Amrein L, Petruccelli L, Birman E, et al. Metformin reduces endogenous reactive oxygen species and associated DNA damage. Cancer Prev Res (Phila). 2012;5:536-43 pubmed 出版商 |
| Bouffet E, Hawkins C, Ballourah W, Taylor M, Bartels U, Schoenhoff N, et al. Survival benefit for pediatric patients with recurrent ependymoma treated with reirradiation. Int J Radiat Oncol Biol Phys. 2012;83:1541-8 pubmed 出版商 |
| Sappino A, Buser R, Lesne L, Gimelli S, Bena F, Belin D, et al. Aluminium chloride promotes anchorage-independent growth in human mammary epithelial cells. J Appl Toxicol. 2012;32:233-43 pubmed 出版商 |
| Spagnolo L, Barbeau J, Curtin N, Morris E, Pearl L. Visualization of a DNA-PK/PARP1 complex. Nucleic Acids Res. 2012;40:4168-77 pubmed 出版商 |
| Yeung P, Denissova N, Nasello C, Hakhverdyan Z, Chen J, Brenneman M. Promyelocytic leukemia nuclear bodies support a late step in DNA double-strand break repair by homologous recombination. J Cell Biochem. 2012;113:1787-99 pubmed 出版商 |
| Ting H, Yasmin Karim S, Yan S, Hsu J, Lin T, Zeng W, et al. A positive feedback signaling loop between ATM and the vitamin D receptor is critical for cancer chemoprevention by vitamin D. Cancer Res. 2012;72:958-68 pubmed 出版商 |
| Fujinaka Y, Matsuoka K, Iimori M, Tuul M, Sakasai R, Yoshinaga K, et al. ATR-Chk1 signaling pathway and homologous recombinational repair protect cells from 5-fluorouracil cytotoxicity. DNA Repair (Amst). 2012;11:247-58 pubmed 出版商 |
| Gomes J, Magalhaes A, Michel V, Amado I, Aranha P, Ovesen R, et al. Pteridium aquilinum and its ptaquiloside toxin induce DNA damage response in gastric epithelial cells, a link with gastric carcinogenesis. Toxicol Sci. 2012;126:60-71 pubmed 出版商 |
| Xiong H, Lee R, Haura E, Edwards J, Dynan W, Li S. Intranuclear delivery of a novel antibody-derived radiosensitizer targeting the DNA-dependent protein kinase catalytic subunit. Int J Radiat Oncol Biol Phys. 2012;83:1023-30 pubmed 出版商 |
| Arakawa H, Bednar T, Wang M, Paul K, Mladenov E, Bencsik Theilen A, et al. Functional redundancy between DNA ligases I and III in DNA replication in vertebrate cells. Nucleic Acids Res. 2012;40:2599-610 pubmed 出版商 |
| Le Bouffant R, Souquet B, Duval N, Duquenne C, Hervé R, Frydman N, et al. Msx1 and Msx2 promote meiosis initiation. Development. 2011;138:5393-402 pubmed 出版商 |
| Morita Y, Iwai S, Kuraoka I. A method for detecting genetic toxicity using the RNA synthesis response to DNA damage. J Toxicol Sci. 2011;36:515-21 pubmed |
| Moraes M, de Andrade A, Carvalho H, Guecheva T, Agnoletto M, Henriques J, et al. Both XPA and DNA polymerase eta are necessary for the repair of doxorubicin-induced DNA lesions. Cancer Lett. 2012;314:108-18 pubmed 出版商 |
| Chassot A, Gregoire E, Lavery R, Taketo M, de Rooij D, Adams I, et al. RSPO1/?-catenin signaling pathway regulates oogonia differentiation and entry into meiosis in the mouse fetal ovary. PLoS ONE. 2011;6:e25641 pubmed 出版商 |
| Shamanna R, Hoque M, Lewis Antes A, Azzam E, Lagunoff D, PE ERY T, et al. The NF90/NF45 complex participates in DNA break repair via nonhomologous end joining. Mol Cell Biol. 2011;31:4832-43 pubmed 出版商 |
| Rosengardten Y, McKenna T, Grochova D, Eriksson M. Stem cell depletion in Hutchinson-Gilford progeria syndrome. Aging Cell. 2011;10:1011-20 pubmed 出版商 |
| Krijger P, van den Berk P, Wit N, Langerak P, Jansen J, Reynaud C, et al. PCNA ubiquitination-independent activation of polymerase ? during somatic hypermutation and DNA damage tolerance. DNA Repair (Amst). 2011;10:1051-9 pubmed 出版商 |
| Cheng Q, Barboule N, Frit P, Gomez D, Bombarde O, Couderc B, et al. Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks. Nucleic Acids Res. 2011;39:9605-19 pubmed 出版商 |
| Lin Z, Lee Y, Lin F, Belcourt M, Li P, Cory J, et al. Reduced level of ribonucleotide reductase R2 subunits increases dependence on homologous recombination repair of cisplatin-induced DNA damage. Mol Pharmacol. 2011;80:1000-12 pubmed 出版商 |
| DeRan M, Pulvino M, Zhao J. Assessing G1-to-S-phase progression after genotoxic stress. Methods Mol Biol. 2011;782:221-30 pubmed 出版商 |
| Catts V, Catts S, Jablensky A, Chandler D, Weickert C, Lavin M. Evidence of aberrant DNA damage response signalling but normal rates of DNA repair in dividing lymphoblasts from patients with schizophrenia. World J Biol Psychiatry. 2012;13:114-25 pubmed 出版商 |
| Lin R, Zhou N, Lyu Y, Tsai Y, Lu C, Kerrigan J, et al. Dietary isothiocyanate-induced apoptosis via thiol modification of DNA topoisomerase II?. J Biol Chem. 2011;286:33591-600 pubmed 出版商 |
| Bridges K, Hirai H, Buser C, Brooks C, Liu H, Buchholz T, et al. MK-1775, a novel Wee1 kinase inhibitor, radiosensitizes p53-defective human tumor cells. Clin Cancer Res. 2011;17:5638-48 pubmed 出版商 |
| Dubois D, Baron O, Cougnoux A, Delmas J, Pradel N, Boury M, et al. ClbP is a prototype of a peptidase subgroup involved in biosynthesis of nonribosomal peptides. J Biol Chem. 2011;286:35562-70 pubmed 出版商 |
| Tsai Y, Lin C, Chiang S, Lee C, Lee K, Ko Y. Areca nut induces miR-23a and inhibits repair of DNA double-strand breaks by targeting FANCG. Toxicol Sci. 2011;123:480-90 pubmed 出版商 |
| Yahata T, Takanashi T, Muguruma Y, Ibrahim A, Matsuzawa H, Uno T, et al. Accumulation of oxidative DNA damage restricts the self-renewal capacity of human hematopoietic stem cells. Blood. 2011;118:2941-50 pubmed 出版商 |
| Fradet Turcotte A, Bergeron Labrecque F, Moody C, Lehoux M, Laimins L, Archambault J. Nuclear accumulation of the papillomavirus E1 helicase blocks S-phase progression and triggers an ATM-dependent DNA damage response. J Virol. 2011;85:8996-9012 pubmed 出版商 |
| Frei C, Opitz I, Soltermann A, Fischer B, Moura U, Rehrauer H, et al. Pleural mesothelioma side populations have a precursor phenotype. Carcinogenesis. 2011;32:1324-32 pubmed 出版商 |
| Dittmann K, Mayer C, Fehrenbacher B, Schaller M, Kehlbach R, Rodemann H. Nuclear epidermal growth factor receptor modulates cellular radio-sensitivity by regulation of chromatin access. Radiother Oncol. 2011;99:317-22 pubmed 出版商 |
| Le Masson F, Razak Z, Kaigo M, Audouard C, Charry C, Cooke H, et al. Identification of heat shock factor 1 molecular and cellular targets during embryonic and adult female meiosis. Mol Cell Biol. 2011;31:3410-23 pubmed 出版商 |
| Rego M, Harney J, Mauro M, Shen M, Howlett N. Regulation of the activation of the Fanconi anemia pathway by the p21 cyclin-dependent kinase inhibitor. Oncogene. 2012;31:366-75 pubmed 出版商 |
| Harding S, Coackley C, Bristow R. ATM-dependent phosphorylation of 53BP1 in response to genomic stress in oxic and hypoxic cells. Radiother Oncol. 2011;99:307-12 pubmed 出版商 |
| Rolyan H, Scheffold A, Heinrich A, Begus Nahrmann Y, Langkopf B, Holter S, et al. Telomere shortening reduces Alzheimer's disease amyloid pathology in mice. Brain. 2011;134:2044-56 pubmed 出版商 |
| Viana Pereira M, Lee A, Popov S, Bax D, Al Sarraj S, Bridges L, et al. Microsatellite instability in pediatric high grade glioma is associated with genomic profile and differential target gene inactivation. PLoS ONE. 2011;6:e20588 pubmed 出版商 |
| Hawkins C, Walker E, Mohamed N, Zhang C, Jacob K, Shirinian M, et al. BRAF-KIAA1549 fusion predicts better clinical outcome in pediatric low-grade astrocytoma. Clin Cancer Res. 2011;17:4790-8 pubmed 出版商 |
| Sung H, Ma W, Starost M, Lago C, Lim P, Sack M, et al. Ambient oxygen promotes tumorigenesis. PLoS ONE. 2011;6:e19785 pubmed 出版商 |
| Stoimenov I, Schultz N, Gottipati P, Helleday T. Transcription inhibition by DRB potentiates recombinational repair of UV lesions in mammalian cells. PLoS ONE. 2011;6:e19492 pubmed 出版商 |
| Li H, Wang Y, Pazhanisamy S, Shao L, Batinic Haberle I, Meng A, et al. Mn(III) meso-tetrakis-(N-ethylpyridinium-2-yl) porphyrin mitigates total body irradiation-induced long-term bone marrow suppression. Free Radic Biol Med. 2011;51:30-7 pubmed 出版商 |
| Suzuki K, Mitsutake N, Saenko V, Suzuki M, Matsuse M, Ohtsuru A, et al. Dedifferentiation of human primary thyrocytes into multilineage progenitor cells without gene introduction. PLoS ONE. 2011;6:e19354 pubmed 出版商 |
| Kalfalah F, Mielke C, Christensen M, Baechler S, Marko D, Boege F. Genotoxicity of dietary, environmental and therapeutic topoisomerase II poisons is uniformly correlated to prolongation of enzyme DNA residence. Mol Nutr Food Res. 2011;55 Suppl 1:S127-42 pubmed 出版商 |
| Wu L, Shao L, An N, Wang J, Pazhanisamy S, Feng W, et al. IKK? regulates the repair of DNA double-strand breaks induced by ionizing radiation in MCF-7 breast cancer cells. PLoS ONE. 2011;6:e18447 pubmed 出版商 |
| Schindler M, Bourland J, Forbes M, Hua K, Riddle D. Neurobiological responses to stereotactic focal irradiation of the adult rodent hippocampus. J Neurol Sci. 2011;306:129-37 pubmed 出版商 |
| Di Giacomo F, Granotier C, Barroca V, Laurent D, Boussin F, Lewandowski D, et al. Tritium contamination of hematopoietic stem cells alters long-term hematopoietic reconstitution. Int J Radiat Biol. 2011;87:556-70 pubmed 出版商 |
| Castillo P, Bogliolo M, Surralles J. Coordinated action of the Fanconi anemia and ataxia telangiectasia pathways in response to oxidative damage. DNA Repair (Amst). 2011;10:518-25 pubmed 出版商 |
| Pazhanisamy S, Li H, Wang Y, Batinic Haberle I, Zhou D. NADPH oxidase inhibition attenuates total body irradiation-induced haematopoietic genomic instability. Mutagenesis. 2011;26:431-5 pubmed 出版商 |
| Benatti P, Dolfini D, Vigano A, Ravo M, Weisz A, Imbriano C. Specific inhibition of NF-Y subunits triggers different cell proliferation defects. Nucleic Acids Res. 2011;39:5356-68 pubmed 出版商 |
| Ardolino M, Zingoni A, Cerboni C, Cecere F, Soriani A, Iannitto M, et al. DNAM-1 ligand expression on Ag-stimulated T lymphocytes is mediated by ROS-dependent activation of DNA-damage response: relevance for NK-T cell interaction. Blood. 2011;117:4778-86 pubmed 出版商 |
| Wei W, Yang Z, Tang C, Liu L. Targeted deletion of GSNOR in hepatocytes of mice causes nitrosative inactivation of O6-alkylguanine-DNA alkyltransferase and increased sensitivity to genotoxic diethylnitrosamine. Carcinogenesis. 2011;32:973-7 pubmed 出版商 |
| Zhuang W, Li B, Long L, Chen L, Huang Q, Liang Z. Induction of autophagy promotes differentiation of glioma-initiating cells and their radiosensitivity. Int J Cancer. 2011;129:2720-31 pubmed 出版商 |
| Ling S, Lin W. EDD inhibits ATM-mediated phosphorylation of p53. J Biol Chem. 2011;286:14972-82 pubmed 出版商 |
| Ye W, Blain S. Chk1 has an essential role in the survival of differentiated cortical neurons in the absence of DNA damage. Apoptosis. 2011;16:449-59 pubmed 出版商 |
| Takahashi M, Koi M, Balaguer F, Boland C, Goel A. MSH3 mediates sensitization of colorectal cancer cells to cisplatin, oxaliplatin, and a poly(ADP-ribose) polymerase inhibitor. J Biol Chem. 2011;286:12157-65 pubmed 出版商 |
| Galron R, Gruber R, Lifshitz V, Lu H, Kirshner M, Ziv N, et al. Astrocyte dysfunction associated with cerebellar attrition in a Nijmegen breakage syndrome animal model. J Mol Neurosci. 2011;45:202-11 pubmed 出版商 |
| Chen H, Ma Z, VanderWaal R, Feng Z, Gonzalez Suarez I, Wang S, et al. The mTOR inhibitor rapamycin suppresses DNA double-strand break repair. Radiat Res. 2011;175:214-24 pubmed |
| Stephan A, Kliszczak M, Dodson H, Cooley C, Morrison C. Roles of vertebrate Smc5 in sister chromatid cohesion and homologous recombinational repair. Mol Cell Biol. 2011;31:1369-81 pubmed 出版商 |
| Stoepker C, Hain K, Schuster B, Hilhorst Hofstee Y, Rooimans M, Steltenpool J, et al. SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype. Nat Genet. 2011;43:138-41 pubmed 出版商 |
| Zhang Y, Regairaz M, Seiler J, Agama K, Doroshow J, Pommier Y. Poly(ADP-ribose) polymerase and XPF-ERCC1 participate in distinct pathways for the repair of topoisomerase I-induced DNA damage in mammalian cells. Nucleic Acids Res. 2011;39:3607-20 pubmed 出版商 |
| Zhang K, Wu J, Wu X, Wang X, Wang Y, Zhou N, et al. p53R2 inhibits the proliferation of human cancer cells in association with cell-cycle arrest. Mol Cancer Ther. 2011;10:269-78 pubmed 出版商 |
| Houlard M, Artus J, Léguillier T, Vandormael Pournin S, Cohen Tannoudji M. DNA-RNA hybrids contribute to the replication dependent genomic instability induced by Omcg1 deficiency. Cell Cycle. 2011;10:108-17 pubmed |
| Rothkamm K, Burdak Rothkamm S. Ionizing radiation-induced DNA strand breaks and ?-H2AX?-H2AX foci in cells exposed to nitric oxide. Methods Mol Biol. 2011;704:17-25 pubmed 出版商 |
| Verbruggen P, Ruf M, Blakqori G, Overby A, Heidemann M, Eick D, et al. Interferon antagonist NSs of La Crosse virus triggers a DNA damage response-like degradation of transcribing RNA polymerase II. J Biol Chem. 2011;286:3681-92 pubmed 出版商 |
| Gilad O, Nabet B, Ragland R, Schoppy D, Smith K, Durham A, et al. Combining ATR suppression with oncogenic Ras synergistically increases genomic instability, causing synthetic lethality or tumorigenesis in a dosage-dependent manner. Cancer Res. 2010;70:9693-702 pubmed 出版商 |
| Elliott S, Crawford C, Mulligan E, Summerfield G, Newton P, Wallis J, et al. Mitoxantrone in combination with an inhibitor of DNA-dependent protein kinase: a potential therapy for high risk B-cell chronic lymphocytic leukaemia. Br J Haematol. 2011;152:61-71 pubmed 出版商 |
| Stoimenov I, Gottipati P, Schultz N, Helleday T. Transcription inhibition by 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) causes DNA damage and triggers homologous recombination repair in mammalian cells. Mutat Res. 2011;706:1-6 pubmed 出版商 |
| Du G, Dutta N, Lashmit P, Stinski M. Alternative splicing of the human cytomegalovirus major immediate-early genes affects infectious-virus replication and control of cellular cyclin-dependent kinase. J Virol. 2011;85:804-17 pubmed 出版商 |
| Redon C, Nakamura A, Sordet O, Dickey J, Gouliaeva K, Tabb B, et al. ?-H2AX detection in peripheral blood lymphocytes, splenocytes, bone marrow, xenografts, and skin. Methods Mol Biol. 2011;682:249-70 pubmed 出版商 |
| Bauerschmidt C, Woodcock M, Stevens D, Hill M, Rothkamm K, Helleday T. Cohesin phosphorylation and mobility of SMC1 at ionizing radiation-induced DNA double-strand breaks in human cells. Exp Cell Res. 2011;317:330-7 pubmed 出版商 |
| De Zio D, Bordi M, Tino E, Lanzuolo C, Ferraro E, Mora E, et al. The DNA repair complex Ku70/86 modulates Apaf1 expression upon DNA damage. Cell Death Differ. 2011;18:516-27 pubmed 出版商 |
| Nykky J, Tuusa J, Kirjavainen S, Vuento M, Gilbert L. Mechanisms of cell death in canine parvovirus-infected cells provide intuitive insights to developing nanotools for medicine. Int J Nanomedicine. 2010;5:417-28 pubmed |
| Bastus N, Boyd L, Mao X, Stankiewicz E, Kudahetti S, Oliver R, et al. Androgen-induced TMPRSS2:ERG fusion in nonmalignant prostate epithelial cells. Cancer Res. 2010;70:9544-8 pubmed 出版商 |
| Kinders R, Hollingshead M, Lawrence S, JI J, Tabb B, Bonner W, et al. Development of a validated immunofluorescence assay for ?H2AX as a pharmacodynamic marker of topoisomerase I inhibitor activity. Clin Cancer Res. 2010;16:5447-57 pubmed 出版商 |
| Landsverk H, Mora Bermúdez F, Landsverk O, Hasvold G, Naderi S, Bakke O, et al. The protein phosphatase 1 regulator PNUTS is a new component of the DNA damage response. EMBO Rep. 2010;11:868-75 pubmed 出版商 |
| Kanu N, Penicud K, Hristova M, Wong B, Irvine E, Plattner F, et al. The ATM cofactor ATMIN protects against oxidative stress and accumulation of DNA damage in the aging brain. J Biol Chem. 2010;285:38534-42 pubmed 出版商 |
| Inanç B, Dodson H, Morrison C. A centrosome-autonomous signal that involves centriole disengagement permits centrosome duplication in G2 phase after DNA damage. Mol Biol Cell. 2010;21:3866-77 pubmed 出版商 |
| Waterhouse M, Themeli M, Bertz H, Zoumbos N, Finke J, Spyridonidis A. Horizontal DNA transfer from donor to host cells as an alternative mechanism of epithelial chimerism after allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant. 2011;17:319-29 pubmed 出版商 |
| Kuck D, Caulfield T, Lyko F, Medina Franco J. Nanaomycin A selectively inhibits DNMT3B and reactivates silenced tumor suppressor genes in human cancer cells. Mol Cancer Ther. 2010;9:3015-23 pubmed 出版商 |
| Audebert M, Riu A, Jacques C, Hillenweck A, Jamin E, Zalko D, et al. Use of the ?H2AX assay for assessing the genotoxicity of polycyclic aromatic hydrocarbons in human cell lines. Toxicol Lett. 2010;199:182-92 pubmed 出版商 |
| Groehler A, Lannigan D. A chromatin-bound kinase, ERK8, protects genomic integrity by inhibiting HDM2-mediated degradation of the DNA clamp PCNA. J Cell Biol. 2010;190:575-86 pubmed 出版商 |
| Lorvellec M, Dumon S, Maya Mendoza A, Jackson D, Frampton J, GarcÃa P. B-Myb is critical for proper DNA duplication during an unperturbed S phase in mouse embryonic stem cells. Stem Cells. 2010;28:1751-9 pubmed 出版商 |
| Nelson A, Holt J. Impact of RING and BRCT domain mutations on BRCA1 protein stability, localization and recruitment to DNA damage. Radiat Res. 2010;174:1-13 pubmed 出版商 |
| Mao F, Sidorova J, Lauper J, Emond M, Monnat R. The human WRN and BLM RecQ helicases differentially regulate cell proliferation and survival after chemotherapeutic DNA damage. Cancer Res. 2010;70:6548-55 pubmed 出版商 |
| Brown J, Bourke E, Liptrot C, Dockery P, Morrison C. MCPH1/BRIT1 limits ionizing radiation-induced centrosome amplification. Oncogene. 2010;29:5537-44 pubmed 出版商 |
| Ye W, Blain S. S phase entry causes homocysteine-induced death while ataxia telangiectasia and Rad3 related protein functions anti-apoptotically to protect neurons. Brain. 2010;133:2295-312 pubmed 出版商 |
| Abate Daga D, Garcia Rodríguez L, Sumoy L, Fillat C. Cell cycle control pathways act as conditioning factors for TK/GCV sensitivity in pancreatic cancer cells. Biochim Biophys Acta. 2010;1803:1175-85 pubmed 出版商 |
| Gottipati P, Vischioni B, Schultz N, Solomons J, Bryant H, Djureinovic T, et al. Poly(ADP-ribose) polymerase is hyperactivated in homologous recombination-defective cells. Cancer Res. 2010;70:5389-98 pubmed 出版商 |
| Liang S, Mele J, Wu Y, Buffenstein R, Hornsby P. Resistance to experimental tumorigenesis in cells of a long-lived mammal, the naked mole-rat (Heterocephalus glaber). Aging Cell. 2010;9:626-35 pubmed 出版商 |
| Wang Z, Rhee D, Lu J, Bohr C, Zhou F, Vallabhaneni H, et al. Characterization of oxidative guanine damage and repair in mammalian telomeres. PLoS Genet. 2010;6:e1000951 pubmed 出版商 |
| Meyer S, Peace B, Bahassi E, Kavanaugh G, Wagh P, Robbins S, et al. Chk2*1100delC Acts in synergy with the Ron receptor tyrosine kinase to accelerate mammary tumorigenesis in mice. Cancer Lett. 2010;296:186-93 pubmed 出版商 |
| Arora S, Kothandapani A, Tillison K, Kalman Maltese V, Patrick S. Downregulation of XPF-ERCC1 enhances cisplatin efficacy in cancer cells. DNA Repair (Amst). 2010;9:745-53 pubmed 出版商 |
| Mukhopadhyay A, Elattar A, Cerbinskaite A, Wilkinson S, Drew Y, Kyle S, et al. Development of a functional assay for homologous recombination status in primary cultures of epithelial ovarian tumor and correlation with sensitivity to poly(ADP-ribose) polymerase inhibitors. Clin Cancer Res. 2010;16:2344-51 pubmed 出版商 |
| Adams B, Golding S, Rao R, Valerie K. Dynamic dependence on ATR and ATM for double-strand break repair in human embryonic stem cells and neural descendants. PLoS ONE. 2010;5:e10001 pubmed 出版商 |
| Le O, Rodier F, Fontaine F, Coppe J, Campisi J, DeGregori J, et al. Ionizing radiation-induced long-term expression of senescence markers in mice is independent of p53 and immune status. Aging Cell. 2010;9:398-409 pubmed 出版商 |
| Sakasai R, Teraoka H, Takagi M, Tibbetts R. Transcription-dependent activation of ataxia telangiectasia mutated prevents DNA-dependent protein kinase-mediated cell death in response to topoisomerase I poison. J Biol Chem. 2010;285:15201-8 pubmed 出版商 |
| Mitchell J, Choudhuri R, Fabre K, Sowers A, Citrin D, Zabludoff S, et al. In vitro and in vivo radiation sensitization of human tumor cells by a novel checkpoint kinase inhibitor, AZD7762. Clin Cancer Res. 2010;16:2076-84 pubmed 出版商 |
| Orsburn B, Escudero B, Prakash M, Gesheva S, Liu G, Huso D, et al. Differential requirement for H2AX and 53BP1 in organismal development and genome maintenance in the absence of poly(ADP)ribosyl polymerase 1. Mol Cell Biol. 2010;30:2341-52 pubmed 出版商 |
| Legendre A, Froment P, Desmots S, Lecomte A, Habert R, Lemazurier E. An engineered 3D blood-testis barrier model for the assessment of reproductive toxicity potential. Biomaterials. 2010;31:4492-505 pubmed 出版商 |
| Mandriota S, Buser R, Lesne L, Stouder C, Favaudon V, Maechler P, et al. Ataxia telangiectasia mutated (ATM) inhibition transforms human mammary gland epithelial cells. J Biol Chem. 2010;285:13092-106 pubmed 出版商 |
| McNeely S, Conti C, Sheikh T, Patel H, Zabludoff S, Pommier Y, et al. Chk1 inhibition after replicative stress activates a double strand break response mediated by ATM and DNA-dependent protein kinase. Cell Cycle. 2010;9:995-1004 pubmed |
| Soule B, Simone N, DeGraff W, Choudhuri R, Cook J, Mitchell J. Loratadine dysregulates cell cycle progression and enhances the effect of radiation in human tumor cell lines. Radiat Oncol. 2010;5:8 pubmed 出版商 |
| Glauser D, Seyffert M, Strasser R, Franchini M, Laimbacher A, Dresch C, et al. Inhibition of herpes simplex virus type 1 replication by adeno-associated virus rep proteins depends on their combined DNA-binding and ATPase/helicase activities. J Virol. 2010;84:3808-24 pubmed 出版商 |
| Belzile J, Richard J, Rougeau N, Xiao Y, Cohen E. HIV-1 Vpr induces the K48-linked polyubiquitination and proteasomal degradation of target cellular proteins to activate ATR and promote G2 arrest. J Virol. 2010;84:3320-30 pubmed 出版商 |
| Hicks J, Chute C, Paulsen M, Ragland R, Howlett N, Gueranger Q, et al. Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links. Mol Cell Biol. 2010;30:1217-30 pubmed 出版商 |
| Lee J, Kang Y, Khare V, Jin Z, Kang M, Yoon Y, et al. The p53-inducible gene 3 (PIG3) contributes to early cellular response to DNA damage. Oncogene. 2010;29:1431-50 pubmed 出版商 |
| Fan Y, Boivin G, Knudsen E, Nebert D, Xia Y, Puga A. The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis. Cancer Res. 2010;70:212-20 pubmed 出版商 |
| Kibe T, Osawa G, Keegan C, de Lange T. Telomere protection by TPP1 is mediated by POT1a and POT1b. Mol Cell Biol. 2010;30:1059-66 pubmed 出版商 |
| Lizé M, Pilarski S, Dobbelstein M. E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosis. Cell Death Differ. 2010;17:452-8 pubmed 出版商 |
| Pospelova T, Demidenko Z, Bukreeva E, Pospelov V, Gudkov A, Blagosklonny M. Pseudo-DNA damage response in senescent cells. Cell Cycle. 2009;8:4112-8 pubmed |
| Wang Y, Liu L, Pazhanisamy S, Li H, Meng A, Zhou D. Total body irradiation causes residual bone marrow injury by induction of persistent oxidative stress in murine hematopoietic stem cells. Free Radic Biol Med. 2010;48:348-56 pubmed 出版商 |
| Bauerschmidt C, Arrichiello C, Burdak Rothkamm S, Woodcock M, Hill M, Stevens D, et al. Cohesin promotes the repair of ionizing radiation-induced DNA double-strand breaks in replicated chromatin. Nucleic Acids Res. 2010;38:477-87 pubmed 出版商 |
| Wilson P, Nham P, Urbin S, Hinz J, Jones I, Thompson L. Inter-individual variation in DNA double-strand break repair in human fibroblasts before and after exposure to low doses of ionizing radiation. Mutat Res. 2010;683:91-7 pubmed 出版商 |
| Britton S, Frit P, Biard D, Salles B, Calsou P. ARTEMIS nuclease facilitates apoptotic chromatin cleavage. Cancer Res. 2009;69:8120-6 pubmed 出版商 |
| Ciccia A, Bredemeyer A, Sowa M, Terret M, Jallepalli P, Harper J, et al. The SIOD disorder protein SMARCAL1 is an RPA-interacting protein involved in replication fork restart. Genes Dev. 2009;23:2415-25 pubmed 出版商 |
| Wu S, Hu Y, Liu H, Shi Y. Loss of YY1 impacts the heterochromatic state and meiotic double-strand breaks during mouse spermatogenesis. Mol Cell Biol. 2009;29:6245-56 pubmed 出版商 |
| Msiska Z, Pacurari M, Mishra A, Leonard S, Castranova V, Vallyathan V. DNA double-strand breaks by asbestos, silica, and titanium dioxide: possible biomarker of carcinogenic potential?. Am J Respir Cell Mol Biol. 2010;43:210-9 pubmed 出版商 |
| Li S, Kuhne W, Kulharya A, Hudson F, Ha K, Cao Z, et al. Involvement of p54(nrb), a PSF partner protein, in DNA double-strand break repair and radioresistance. Nucleic Acids Res. 2009;37:6746-53 pubmed 出版商 |
| Pegoraro G, Kubben N, Wickert U, Göhler H, Hoffmann K, Misteli T. Ageing-related chromatin defects through loss of the NURD complex. Nat Cell Biol. 2009;11:1261-7 pubmed 出版商 |
| Cook J, Choudhuri R, DeGraff W, Gamson J, Mitchell J. Halofuginone enhances the radiation sensitivity of human tumor cell lines. Cancer Lett. 2010;289:119-26 pubmed 出版商 |
| Rapisarda A, Hollingshead M, Uranchimeg B, Bonomi C, Borgel S, Carter J, et al. Increased antitumor activity of bevacizumab in combination with hypoxia inducible factor-1 inhibition. Mol Cancer Ther. 2009;8:1867-77 pubmed 出版商 |
| Alajez N, Shi W, Hui A, Yue S, Ng R, Lo K, et al. Targeted depletion of BMI1 sensitizes tumor cells to P53-mediated apoptosis in response to radiation therapy. Cell Death Differ. 2009;16:1469-79 pubmed 出版商 |
| Rusin M, Zajkowicz A, Butkiewicz D. Resveratrol induces senescence-like growth inhibition of U-2 OS cells associated with the instability of telomeric DNA and upregulation of BRCA1. Mech Ageing Dev. 2009;130:528-37 pubmed 出版商 |
| Liontos M, Niforou K, Velimezi G, Vougas K, Evangelou K, Apostolopoulou K, et al. Modulation of the E2F1-driven cancer cell fate by the DNA damage response machinery and potential novel E2F1 targets in osteosarcomas. Am J Pathol. 2009;175:376-91 pubmed 出版商 |
| Simonnet A, Nehme J, Vaigot P, Barroca V, Leboulch P, Tronik Le Roux D. Phenotypic and functional changes induced in hematopoietic stem/progenitor cells after gamma-ray radiation exposure. Stem Cells. 2009;27:1400-9 pubmed 出版商 |
| Zarebski M, Wiernasz E, Dobrucki J. Recruitment of heterochromatin protein 1 to DNA repair sites. Cytometry A. 2009;75:619-25 pubmed 出版商 |
| Huda N, Tanaka H, Mendonca M, Gilley D. DNA damage-induced phosphorylation of TRF2 is required for the fast pathway of DNA double-strand break repair. Mol Cell Biol. 2009;29:3597-604 pubmed 出版商 |
| Golding S, Morgan R, Adams B, Hawkins A, Povirk L, Valerie K. Pro-survival AKT and ERK signaling from EGFR and mutant EGFRvIII enhances DNA double-strand break repair in human glioma cells. Cancer Biol Ther. 2009;8:730-8 pubmed |
| Diermeier Daucher S, Clarke S, Hill D, Vollmann Zwerenz A, Bradford J, Brockhoff G. Cell type specific applicability of 5-ethynyl-2'-deoxyuridine (EdU) for dynamic proliferation assessment in flow cytometry. Cytometry A. 2009;75:535-46 pubmed 出版商 |
| Thaler S, Hähnel P, Schad A, Dammann R, Schuler M. RASSF1A mediates p21Cip1/Waf1-dependent cell cycle arrest and senescence through modulation of the Raf-MEK-ERK pathway and inhibition of Akt. Cancer Res. 2009;69:1748-57 pubmed 出版商 |
| Parsels L, Morgan M, Tanska D, Parsels J, Palmer B, Booth R, et al. Gemcitabine sensitization by checkpoint kinase 1 inhibition correlates with inhibition of a Rad51 DNA damage response in pancreatic cancer cells. Mol Cancer Ther. 2009;8:45-54 pubmed 出版商 |
| Kasten Pisula U, Menegakis A, Brammer I, Borgmann K, Mansour W, Degenhardt S, et al. The extreme radiosensitivity of the squamous cell carcinoma SKX is due to a defect in double-strand break repair. Radiother Oncol. 2009;90:257-64 pubmed 出版商 |
| Perotti C, Liu R, Parusel C, Böcher N, Schultz J, Bork P, et al. Heat shock protein-90-alpha, a prolactin-STAT5 target gene identified in breast cancer cells, is involved in apoptosis regulation. Breast Cancer Res. 2008;10:R94 pubmed 出版商 |
| Schmid U, Stopper H, Schweda F, Queisser N, Schupp N. Angiotensin II induces DNA damage in the kidney. Cancer Res. 2008;68:9239-46 pubmed 出版商 |
| Hein J, Boichuk S, Wu J, Cheng Y, Freire R, Jat P, et al. Simian virus 40 large T antigen disrupts genome integrity and activates a DNA damage response via Bub1 binding. J Virol. 2009;83:117-27 pubmed 出版商 |
| Tabori U, Wong V, Ma J, Shago M, Alon N, Rutka J, et al. Telomere maintenance and dysfunction predict recurrence in paediatric ependymoma. Br J Cancer. 2008;99:1129-35 pubmed 出版商 |
| Enokido Y, Yoshitake A, Ito H, Okazawa H. Age-dependent change of HMGB1 and DNA double-strand break accumulation in mouse brain. Biochem Biophys Res Commun. 2008;376:128-33 pubmed 出版商 |
| Dann C, Alvarado A, Molyneux L, Denard B, Garbers D, Porteus M. Spermatogonial stem cell self-renewal requires OCT4, a factor downregulated during retinoic acid-induced differentiation. Stem Cells. 2008;26:2928-37 pubmed 出版商 |
| Cardaci S, Filomeni G, Rotilio G, Ciriolo M. Reactive oxygen species mediate p53 activation and apoptosis induced by sodium nitroprusside in SH-SY5Y cells. Mol Pharmacol. 2008;74:1234-45 pubmed 出版商 |
| Tsai Y, Lee K, Huang J, Liu Y, Juo S, Kuo W, et al. Arecoline, a major alkaloid of areca nut, inhibits p53, represses DNA repair, and triggers DNA damage response in human epithelial cells. Toxicology. 2008;249:230-7 pubmed 出版商 |
| Burgess D, Doles J, Zender L, Xue W, Ma B, McCombie W, et al. Topoisomerase levels determine chemotherapy response in vitro and in vivo. Proc Natl Acad Sci U S A. 2008;105:9053-8 pubmed 出版商 |
| Barrientos K, Kendellen M, Freibaum B, Armbruster B, Etheridge K, Counter C. Distinct functions of POT1 at telomeres. Mol Cell Biol. 2008;28:5251-64 pubmed 出版商 |
| Vuyyuri S, Hamstra D, Khanna D, Hamilton C, Markwart S, Campbell K, et al. Evaluation of D-methionine as a novel oral radiation protector for prevention of mucositis. Clin Cancer Res. 2008;14:2161-70 pubmed 出版商 |
| Sakasai R, Tibbetts R. RNF8-dependent and RNF8-independent regulation of 53BP1 in response to DNA damage. J Biol Chem. 2008;283:13549-55 pubmed 出版商 |
| Al Ejeh F, Darby J, Brown M. The La autoantigen is a malignancy-associated cell death target that is induced by DNA-damaging drugs. Clin Cancer Res. 2007;13:5509s-5518s pubmed |
| Wu P, Frit P, Malivert L, Revy P, Biard D, Salles B, et al. Interplay between Cernunnos-XLF and nonhomologous end-joining proteins at DNA ends in the cell. J Biol Chem. 2007;282:31937-43 pubmed |
| Marusyk A, Wheeler L, Mathews C, DeGregori J. p53 mediates senescence-like arrest induced by chronic replicational stress. Mol Cell Biol. 2007;27:5336-51 pubmed |
| Kotsopoulos J, Chen Z, Vallis K, Poll A, Ainsworth P, Narod S. DNA repair capacity as a possible biomarker of breast cancer risk in female BRCA1 mutation carriers. Br J Cancer. 2007;96:118-25 pubmed |
| Mallette F, Gaumont Leclerc M, Ferbeyre G. The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence. Genes Dev. 2007;21:43-8 pubmed |
| Rose J, Reeves K, Likhotvorik R, Hoyt D. Base excision repair proteins are required for integrin-mediated suppression of bleomycin-induced DNA breakage in murine lung endothelial cells. J Pharmacol Exp Ther. 2007;321:318-26 pubmed |
| Puc J, Parsons R. PTEN loss inhibits CHK1 to cause double stranded-DNA breaks in cells. Cell Cycle. 2005;4:927-9 pubmed |
