This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
默克密理博中国
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
产品类型 :
抗体
产品名称 :
酪氨酸羟化酶抗体
目录 :
AB1542
规格 :
100微升
克隆性 :
多克隆
宿主 :
家羊
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, domestic rabbit
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片
文章摘录数: 38
出版应用/物种/样本/稀释参考文献
  • 免疫组化-自由浮动切片; 小鼠; 1:1000; 图 1c
Ito H, Sales A, Fry C, Kanai A, Drake M, Pickering A. Probabilistic, spinally-gated control of bladder pressure and autonomous micturition by Barrington's nucleus CRH neurons. elife. 2020;9: pubmed 出版商
  • 免疫组化; 小鼠; 1:150-1:300; 图 3b
Zhang B, Ma S, Rachmin I, He M, Baral P, Choi S, et al. Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells. Nature. 2020;577:676-681 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 3i
Popova D, Desai N, Blendy J, Pang Z. Synaptic regulation by OPRM1 variants in reward neurocircuitry. J Neurosci. 2019;: pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 5b
Zeng X, Ye M, Resch J, Jedrychowski M, Hu B, Lowell B, et al. Innervation of thermogenic adipose tissue via a calsyntenin 3β-S100b axis. Nature. 2019;569:229-235 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:400; 图 7a
Poltavski D, Colombier P, Hu J, Duron A, Black B, Makita T. Venous endothelin modulates responsiveness of cardiac sympathetic axons to arterial semaphorin. elife. 2019;8: pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 s8h
Paul A, Chaker Z, Doetsch F. Hypothalamic regulation of regionally distinct adult neural stem cells and neurogenesis. Science. 2017;356:1383-1386 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000; 图 1f
Cha Y, Han M, Cha H, Zoldan J, Burkart A, Jung J, et al. Metabolic control of primed human pluripotent stem cell fate and function by the miR-200c-SIRT2 axis. Nat Cell Biol. 2017;19:445-456 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:500; 图 1a
Evsyukov V, Domanskyi A, Bierhoff H, Gispert S, Mustafa R, Schlaudraff F, et al. Genetic mutations linked to Parkinson's disease differentially control nucleolar activity in pre-symptomatic mouse models. Dis Model Mech. 2017;10:633-643 pubmed 出版商
  • 免疫组化; 小鼠; 1:3000; 图 2b
Wang J, O Sullivan M, Mukherjee D, Punal V, Farsiu S, Kay J. Anatomy and spatial organization of Müller glia in mouse retina. J Comp Neurol. 2017;525:1759-1777 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:100; 图 s23b
Ho Y, Zhou L, Tam K, Too H. Enhanced non-viral gene delivery by coordinated endosomal release and inhibition of β-tubulin deactylase. Nucleic Acids Res. 2017;45:e38 pubmed 出版商
  • 免疫组化; 小鼠; 1:800; 图 8
Carnevale D, Perrotta M, Pallante F, Fardella V, Iacobucci R, Fardella S, et al. A cholinergic-sympathetic pathway primes immunity in hypertension and mediates brain-to-spleen communication. Nat Commun. 2016;7:13035 pubmed 出版商
  • 免疫细胞化学; domestic rabbit; 1:800; 图 3
Inokaitis H, Pauziene N, Rysevaite Kyguoliene K, Pauza D. Innervation of sinoatrial nodal cells in the rabbit. Ann Anat. 2016;205:113-21 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:1000; 图 2
  • 免疫组化; 小鼠; 1:1000; 图 1
Srinivasan R, Henley B, Henderson B, Indersmitten T, Cohen B, Kim C, et al. Smoking-Relevant Nicotine Concentration Attenuates the Unfolded Protein Response in Dopaminergic Neurons. J Neurosci. 2016;36:65-79 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:1000; 图 11
Geerling J, Kim M, Mahoney C, Abbott S, Agostinelli L, Garfield A, et al. Genetic identity of thermosensory relay neurons in the lateral parabrachial nucleus. Am J Physiol Regul Integr Comp Physiol. 2016;310:R41-54 pubmed 出版商
Lavin T, Jin L, Lea N, Wickersham I. Monosynaptic Tracing Success Depends Critically on Helper Virus Concentrations. Front Synaptic Neurosci. 2020;12:6 pubmed 出版商
Yan Y, Beckley N, Kim V, Drenan R. Differential Nicotinic Modulation of Glutamatergic and GABAergic VTA Microcircuits. Eneuro. 2019;6: pubmed 出版商
Paixão S, Loschek L, Gaitanos L, Alcalà Morales P, Goulding M, Klein R. Identification of Spinal Neurons Contributing to the Dorsal Column Projection Mediating Fine Touch and Corrective Motor Movements. Neuron. 2019;104:749-764.e6 pubmed 出版商
Berger J, Singh P, Khrimian L, Morgan D, Chowdhury S, Arteaga Solis E, et al. Mediation of the Acute Stress Response by the Skeleton. Cell Metab. 2019;30:890-902.e8 pubmed 出版商
Miyamoto Y, Nagayoshi I, Nishi A, Fukuda T. Three divisions of the mouse caudal striatum differ in the proportions of dopamine D1 and D2 receptor-expressing cells, distribution of dopaminergic axons, and composition of cholinergic and GABAergic interneurons. Brain Struct Funct. 2019;224:2703-2716 pubmed 出版商
Rajendran P, Challis R, Fowlkes C, Hanna P, Tompkins J, Jordan M, et al. Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies. Nat Commun. 2019;10:1944 pubmed 出版商
Pristerá A, Blomeley C, Lopes E, Threlfell S, Merlini E, Burdakov D, et al. Dopamine neuron-derived IGF-1 controls dopamine neuron firing, skill learning, and exploration. Proc Natl Acad Sci U S A. 2019;116:3817-3826 pubmed 出版商
Pérez Fernández V, Milosavljevic N, Allen A, Vessey K, Jobling A, Fletcher E, et al. Rod Photoreceptor Activation Alone Defines the Release of Dopamine in the Retina. Curr Biol. 2019;: pubmed 出版商
McWilliams T, Barini E, Pohjolan Pirhonen R, Brooks S, Singh F, Burel S, et al. Phosphorylation of Parkin at serine 65 is essential for its activation in vivo. Open Biol. 2018;8: pubmed 出版商
Kremer M, Yalcin I, Goumon Y, Wurtz X, Nexon L, Daniel D, et al. A Dual Noradrenergic Mechanism for the Relief of Neuropathic Allodynia by the Antidepressant Drugs Duloxetine and Amitriptyline. J Neurosci. 2018;38:9934-9954 pubmed 出版商
Sharma S, Kim L, Mayr K, Elliott D, Whelan P. Parallel descending dopaminergic connectivity of A13 cells to the brainstem locomotor centers. Sci Rep. 2018;8:7972 pubmed 出版商
Henrich M, Geibl F, Lee B, Chiu W, Koprich J, Brotchie J, et al. A53T-α-synuclein overexpression in murine locus coeruleus induces Parkinson's disease-like pathology in neurons and glia. Acta Neuropathol Commun. 2018;6:39 pubmed 出版商
Dawes J, Weir G, Middleton S, Patel R, Chisholm K, Pettingill P, et al. Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability. Neuron. 2018;97:806-822.e10 pubmed 出版商
McWilliams T, Prescott A, Montava Garriga L, Ball G, Singh F, Barini E, et al. Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand. Cell Metab. 2018;27:439-449.e5 pubmed 出版商
Burnham N, Thiele T. Voluntary Binge-like Ethanol Consumption Site-specifically Increases c-Fos Immunoexpression in Male C57BL6/J Mice. Neuroscience. 2017;367:159-168 pubmed 出版商
Ruiz de Azua I, Mancini G, Srivastava R, Rey A, Cardinal P, Tedesco L, et al. Adipocyte cannabinoid receptor CB1 regulates energy homeostasis and alternatively activated macrophages. J Clin Invest. 2017;127:4148-4162 pubmed 出版商
McWilliams T, Howard L, Wyatt S, Davies A. TNF superfamily member APRIL enhances midbrain dopaminergic axon growth and contributes to the nigrostriatal projection in vivo. Exp Neurol. 2017;298:97-103 pubmed 出版商
Gao L, Bonilla Henao V, García Flores P, Arias Mayenco I, Ortega Saenz P, Lopez Barneo J. Gene expression analyses reveal metabolic specifications in acute O2 -sensing chemoreceptor cells. J Physiol. 2017;595:6091-6120 pubmed 出版商
García González D, Khodosevich K, Watanabe Y, Rollenhagen A, Lübke J, Monyer H. Serotonergic Projections Govern Postnatal Neuroblast Migration. Neuron. 2017;94:534-549.e9 pubmed 出版商
Mesman S, van Hooft J, Smidt M. Mest/Peg1 Is Essential for the Development and Maintenance of a SNc Neuronal Subset. Front Mol Neurosci. 2016;9:166 pubmed 出版商
Doucet Beaupré H, Gilbert C, Profes M, Chabrat A, Pacelli C, Giguère N, et al. Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons. Proc Natl Acad Sci U S A. 2016;113:E4387-96 pubmed 出版商
Bandrowski A, Brush M, Grethe J, Haendel M, Kennedy D, Hill S, et al. The Resource Identification Initiative: a cultural shift in publishing. Brain Behav. 2016;6:e00417 pubmed 出版商
Lelos M, Morgan R, Kelly C, Torres E, Rosser A, Dunnett S. Amelioration of non-motor dysfunctions after transplantation of human dopamine neurons in a model of Parkinson's disease. Exp Neurol. 2016;278:54-61 pubmed 出版商
Root D, Hoffman A, Good C, Zhang S, Gigante E, Lupica C, et al. Norepinephrine activates dopamine D4 receptors in the rat lateral habenula. J Neurosci. 2015;35:3460-9 pubmed 出版商
产品信息
目录代码 :
AB1542
亚类别 :
神经科学
产品名称 :
抗酪氨酸羟化酶抗体
产品类型 :
抗体
克隆性 :
多克隆抗体
基因编号 :
P07101
宿主名称 :
抗原 :
酪氨酸羟化酶
共轭标签 :
亲和纯化
产品描述 :
抗酪氨酸羟化酶抗体
交叉活性 :
哺乳动物;大鼠;小鼠
背景 :
Tyrosine hydroxylase plays an important role in the physiology of adrenergic neurons. It is the first and rate-limiting enzyme involved in the biosynthesis of the catecholamines Dopamine and Norepinephrine from tyrosine. TH is, therefore, a useful marker for dopaminergic and noradrenergic neurons. The enzymatic activity of TH requires ferrous ions as cofactors and is believed to be regulated by phosphorylation. At least four isoforms of human TH have been identified which result from alternative splicing.
别名 :
Tyrosine 3-hydroxylase;Tyrosine 3-hydroxylase;tyrosine hydroxylase
免疫原 :
Native tyrosine hydroxylase from rat pheochromocytoma (J. Biol. Chem.,1982, 257:9416-9423).
特异性 :
Tyrosine Hydroxylase (TH, Tyrosine Monooxygenase). Cross-reacts with all mammalian forms tested to date and some non-mammalian forms.
包装尺寸 :
100微升
用途 :
免疫组化;免疫印迹
储存 :
Stable for 6 months at -20 to -80°C in undiluted aliquots from date of receipt. Store in a NON-self-defrosting freezer. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variabillity in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
公司信息
默克密理博中国
上海市浦东张江高科技园区晨晖路88号2号楼2楼
asiatechserv@millipore.com
http://www.millipore.com/china/wwcn/cnhome
400-889-1988
公司总部: 美国
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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